Ancient olfaction protein is shared by many bugs, offering new pest control target
In the battle against insect pests, new research indicates that it may all come down to the sense of smell. A group of Rockefeller University scientists who had previously identified a key gene essential for the sense of smell in fruit flies now shows that this gene's function appears to be evolutionarily conserved across very different insect species. Research by Leslie Vosshall's laborat...Gene variations explain drug dose required to control seizures
Determining which variants of particular genes patients with epilepsy carry might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University College London. Patients often undergo a lengthy process of trial and error to find the dose of ant...U-M scientists find genes that control growth of common skin cancer
Scientists at the University of Michigan'sComprehensive Cancer Center and the National Cancer Institute haveidentified genes that promote the growth and recurrence of skin cancer.Andrzej Dlugosz, M.D., a professor of dermatology in the U-M MedicalSchool, and colleagues at the University of Michigan and the NationalCancer Institute examined the functions of the Hedgehog (Hh) signalingpathway...UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections
A team led by Johns Hopkins scientists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability to recognize and respond to a milliondifferent proteins might have originated from a family of genes whoseonly apparent function is to jump around in genetic material. essentially cut...Unexpressed But Indispensable -- The DNA Sequences That Control Development
Amidst the hoopla over the exact number of genes we have in our genome—more than a fruitfly, fewer than a rice plant—a more fundamental genetic truth has often been obscured. The expression of 20,000?0,000 genes is under the control of an uncounted host of non-coding sequences, which bind transcription factors and thereby regulate when and where genes are expressed. Unlike coding sequences, whose...pMIR-mU6-Luc, Mouse U6 Luciferase Control Vector from Mirus Bio Corporation
Description:The potential applications for the use of small interfering RNA (siRNA) molecules to silence gene expression via the RNA interference (RNAi) pathway have generated tremendous interest in the cellular and molecular biology fields. siRNA for experimental use can be synthesized in vitro, either chemically or enzymatically, and then transfected into the target cells in vitro or in vivo. A convenient...pMIR-hU6-Luc, Human U6 Luciferase Control Vector from Mirus Bio Corporation
Description:The potential applications for the use of small interfering RNA (siRNA) molecules to silence gene expression via the RNA interference (RNAi) pathway have generated tremendous interest in the cellular and molecular biology fields. siRNA for experimental use can be synthesized in vitro, either chemically or enzymatically, and then transfected into the target cells in vitro or in vivo. A convenient...LabLinx from Hudson Control Group, Inc.
Description:LabLinx is the next step in the evolution of laboratory automation. A high-speed, modular, expandable track system that delivers labware to multiple laboratory instruments, LabLinx gives users up to 10 times the throughput of ordinary microplate robots. It allows the user to setup a variety of configurations to meet any labs specific automation needs, from simple, automated workcells to full-scal...RSH-4000 from Hudson Control Group, Inc.
Description:The RSH-4000 is the only microplate sealer with an integrated in-line plate stacker. It offers long walkaway times with a variety of configurations and sealing capabilities. Features: Fully automated with integrated stacker and 240-plate storage capacity Integrated with Hudsons PlateCrane EX for use in small workcells Handles all SBS microplates and tube racks Variety...micro 1 from Hudson Control Group, Inc.
Description:The micro 1 is a dramatic breakthrough in accurate, small-volume bulk dispensing. Dispensing precise volumes from 1mL with 10nL resolution, the micro 1 has unique advantages not found in any other benchtop dispenser. And, the micro 1 never needs re-calibration as do other 1mL dispensers. Features: Touch Screen programming on an LCD Display Graphical Row Selection 96-,384-...Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance
Stratagene We introduce six pairs of control RT-PCR primers that are designed todetect specific human gene transcripts with various expression levels. Theseprimer sets provide insight into whether cDNA synthesis has been effective forall ab...Versatile Vectors for Ponasterone A- Inducible Control of Gene Expression in Mammalian Cells
Stratagene mammalian expressionsystem allows tightc...Rapid PCR* Using Active Tube Temperature Control On Thermo's PCR Machines
Solutions Note The time taken to complete a standard PCRprotocol is becoming increasingly important forresearchers today. Whilst many manufacturers ofthermal cyclers focus on pushing the limits of ramprates, in this article we highlight how Thermo's approach of focussing on ach...Housekeeping Genes: Universal Positive Controls in siRNA Knockdown Experiments
RNA interference is a powerful technique for geneknockdown experiments in academic research and animportant tool for target identification and target validationin therapeutic research. A growing number of different cell lines are us...FDA's control is inherently weak
The Food and Drug Administration has few details about the dramatic rise in overseas drug testing and reforms are needed to protect both foreign patients taking experimental medicines and Americans who buy products based on their results. The number of pharmaceutical researchers working outside the United States who voluntarily report their experiments to the FDA increased 16-fold from...FDA Approves Birth Control Skin Patch
For the first time, the US Food and Drug Administration (FDA) has approved a contraceptive skin patch for weekly use. Ortho Evra, made by New Jersey-based Johnson & Johnson, is a one-and-three-quarter-inch patch containing the hormones norelgestromin and ethinyl estradiol, designed to be an alternative to birth control pills. // The patch delivers the hormones through the skin for a 1...Drugs control and industry departments to share a common e-platform
The drugs control, health and industry departments in Andhra Pradesh are to have a common e-platform which is both informative and interactive at the same time with the inauguration of www.aponline.gov.in, the state government's latest initiative to integrate all the activities of all its departments under one umbrella. The portal is being developed by Tata Consultancy Services (TCS) as part of a...Endoalpha Centralized O.R. Control System
Description:Olympus' new generation Endoalpha is a centralized O.R. control system that empowers both the surgeon and the nurse by giving them better control, better information and greater efficiencies. Endoalpha provides protection against obsolescence, as future enhancements will mainly require software upgrades rather than the purchase of an entirely new system. Endoalpha is unique in providing superior...US Autoflow Single Chamber Stackable Water-Jacketed CO2 Inc.w/ Humidity Display and Control
Description:US Autoflow Single Chamber Stackable Water-Jacketed CO2 Inc.w/ Humidity Display and Control...Tight Glycemic Control in the ICU
The outcome of many illnesses for which patients are treated in intensive care units (ICUs) has not improved dramatically over the past decades, despite the development of high-tech monitors and sophisticated mechanical and pharmacological support of vital organ systems. Indeed, critically ill patients requiring intensive care for more than five day...New Quality Control Systems for Every Laboratory Application
Quality Control (QC) materials and procedures are key to meeting the needs of doctors and patients by verifying accuracy and precision of analytical methods. Vendors of these systems can be a valuable resource, designing customized QC materials and protocols to help lab managers ensure that analytical error st...Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control
According to the American Diabetes Association, the total annual economic cost of diabetes in 2002 was estimated to be $132 billion, or one out of every 10 health care dollars spent in the United States. A chronic disease with no cure, diabetes is a group of diseases (including Type 1, Type 2, and gestational) marked by...Optimizing Quality Control Data Management
Automation continues to gain importance in modern clinical laboratories in step with increasing test consolidation, rising demands from clinicians for rapid turnaround times, and an ever-mounting shortage of licensed medical technologists. Ultimately, the laboratories that implement high-quality automation solutions are better equipped to meet these modern demands....