FDA Approves Duramed's Synthetic Conjugated Estrogens-A Vaginal Cream

- First Local Estrogen Therapy Indicated for the Treatment of Both Moderate to Severe Vaginal Dryness and Pain With Intercourse - Symptoms of Vulvar and Vaginal Atrophy Due to Menopause - Further Expands Company's Hormone Therapy Product Line MONTVALE, N.J., Dec. 1 /PRNewswire-...

Duramed Launches New Indication for ENJUVIA(TM) (Synthetic Conjugated Estrogens, B) at North American Menopause Society Annual Meeting

WOODCLIFF LAKE, N.J., Oct. 2 /PRNewswire-FirstCall/ -- Duramed Pharmaceuticals, Inc., a subsidiary of Barr Pharmaceuticals, Inc. (NYSE: BRL), announced today the launch of its marketing campaign for ENJUVIA(TM) for the treatment of moderate-to-severe vaginal dryness and pain with intercourse, ...

Dietary Oils May Help Some Fight Fat

...tary oil supplements could help ward off unwanted fat, according to a new study. Obese older women with type 2 diabetes who added safflower oil or conjugated linoleic acid (CLA) supplements to their diet either decreased their body mass index or boosted their muscle mass, researchers found. "I don't thin...

Hormone Therapy Increases Odds of Ovarian Cancer

...the type of hormone preparation they took. However, Wyeth, maker of two conjugated estrogens -- Premarin and Prempro -- said the study didn't have enough women taking conjugated estrogens to determine actual risk for that type of hormone therapy. "T...

Wyeth's Prevenar 13* Receives First Approval

...up to one million deaths in children each year. Prevenar 13, which builds on the scientific foundation of Prevenar* (Pneumococcal Saccharide conjugated Vaccine, Adsorbed), is designed to provide the broadest serotype coverage of any pneumococcal conjugate vaccine. Prevenar 13 contains 13 serotypes, s...

Study Evaluating Efficacy and Safety of Two Low-dose Regimens of PREMARIN Vaginal Cream for the Treatment of Moderate to Severe Vaginal Atrophy Now Published

...erate-to-severe vulvar and vaginal atrophy, including painful intercourse (dyspareunia). This study evaluated the efficacy of two low-dose regimens of conjugated estrogens (CE) cream (0.5 g daily and twice weekly) using a double-blind, placebo-controlled study design for 12 weeks followed by a 40-week open-labe...

conjugated in Medical Technology

TWO NEW KLRI PEER-REVIEWED PUBLICATIONS: Hormone Therapy May Reduce Atherosclerosis in Women Close to Menopause; Growth Hormone May Increase Risk of Diabetes, Improve Lipid Profile in Men

...d Dr. S. Mitchell Harman, M.D., Ph.D., KLRI's Director and President. The Postmenopausal Estrogen/Progestin Interventions (PEPI) trial compared conjugated equine estrogen (CEE) with three different CEE-progestin combinations and placebo in 875 healthy, postmenopausal women, aged 45 to 64. KLRI has found ...

Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms

... was designed to explore the hypothesis that bazedoxifene, when paired with conjugated estrogens, may have the potential to eliminate the need for progestin in me...complex) as it combines a selective estrogen receptor modulator (SERM) with conjugated estrogens. Across the SMART-1 trial, the incidence of treatment-eme...

Raptor Pharmaceuticals Receives Notices of Allowance for Two NeuroTrans(TM) Patent Applications

...rain comprising administering receptor-associated protein ("RAP") fragments conjugated to active agents ." (Logo: http://www.newscom.com/cgi-bin/prnh/200710...ns across the endothelial membrane in the BBB. NeuroTrans(TM) has also been conjugated to a variety of protein drugs, including enzymes and growth factors, withou...

First Candidate from Esperance's Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept

...sive cancers known to be resistant to the current standards of care." Study results : EP-100 consists of an LHRH receptor-targeting ligand conjugated to a novel membrane-disrupting peptide called CLIP 71. The drug candidate was tested in vitro and in vivo for activity in LHRH receptor over-expre...

Immunomedics Announces Preclinical Therapy Results of SN-38 Immunoconjugate for Colorectal Cancer

...DF/PR03202008.pdf ). In this study, the therapeutic efficacy of SN-38 conjugated to labetuzumab was evaluated in two animal models of human colon cancer. L...d antibodies that can be used either alone in unlabeled or "naked" form, or conjugated with radioactive isotopes, chemotherapeutics or toxins, in each case to cre...

Wyeth Submits European Marketing Authorization Application for its 13-Valent Vaccine for the Prevention of Pneumococcal Disease in Infants and Young Children

...neumococcal serotypes associated with serious PD. Seven of these (4, 6B, 9V, 14, 18C, 19F and 23F) are included in Prevenar* (Pneumococcal saccharide conjugated vaccine, adsorbed) - - the current global standard in PD prevention in infants and young children. The six additional serotypes (1, 3, 5, 6A, 7F and 1...

conjugated in Medical Products

Bio-Adembeads Magnetic Beads Conjugated To Streptavidin

Description: Ademtechs Magnetic Beads are produced by encapsulation of a magnetic oil (patented technology). The magnetic content, uniform particle size, mono-dispersion properties, and the high surface area allow the use of 200-500 nm magnetic beads....
Company:BioCat GmbH

Goat Anti-Rabbit IgG Antibody, Gold Conjugated

Description: Colloidal Gold Conjugated, Goat anti-rabbit IgG (H&L) - 12 OD...
Company:BioAssay Works, L.L.C.

Goat Anti-Mouse IgG Antibody, Gold Conjugated

Description: Colloidal Gold Conjugated, Goat anti-mouse IgG (H&L) - 12 OD...
Company:BioAssay Works, L.L.C.

Goat Anti-Human IgM Antibody, Gold Conjugated

Description: Colloidal Gold Conjugated, Goat anti-human IgM (Mu Chain) - 12 OD...
Company:BioAssay Works, L.L.C.

Goat Anti-Human IgG Antibody, Gold Conjugated

Description: Colloidal Gold Conjugated, Goat anti-human IgG (H&L) - 12 OD...
Company:BioAssay Works, L.L.C.

Goat Anti-Goat IgG Antibody, Gold Conjugated

Description: Colloidal Gold Conjugated, Rabbit anti-goat IgG (H&L) - 12 OD...
Company:BioAssay Works, L.L.C.

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conjugated in Biological News

Foods high in conjugated linoleic acids can enrich breast milk

Philadelphia, PA, July 28, 2008 Have a cookie before breast-feeding, mom? Eating special cookies enriched with conjugated linoleic acid (CLA) can increase the level of these potentially healthful fatty acids in breast milk, reports a recent study in the journal Nutrition Research . Led by At...

Two dietary oils, two sets of benefits for older women with diabetes

...tes. The two oils compared were safflower oil, a common cooking oil, and conjugated linoleic acid (CLA), a compound naturally found in some meat and dairy prod...ered blood sugar and increased muscle tissue in the women participants. conjugated linoleic acid supplementation for the same length of time, on the other han...

A new way to assemble cells into 3-D microtissues

...natural sugar biosynthesis limits the kinds of cells that we can use in microtissue construction," she says. "There are other ways in which DNA can be conjugated to cells, independent of their sugar metabolic pathways, and we intend to explore those avenues." ...

American Chemical Society's Weekly PressPac -- Dec. 17, 2008

...other healthful food proteins into useful drugs, the researchers note. MTS ARTICLE #4 FOR IMMEDIATE RELEASE "Development of Poly(ethylene glycol) conjugated Lactoferrin for Oral Administration" DOWNLOAD FULL TEXT ARTICLE http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/bc800258v CONTACT: At...

Using live fish, new tool a sentinel for environmental contamination

...ut there are plans to make the tool more versatile. Porterfield also said he thinks the technology could have diverse uses. He imagines it could be conjugated with tumor cells to screen potential cancer drugs or help find new therapeutic targets. During the study the technology detected four of five commo...

Using carbon nanotubes to seek and destroy anthrax toxin and other harmful proteins

... study at Rensselaer is the first to remotely control the activity of these conjugated nanotubes. Details of the project are outlined in the article Nanotube-Assi...ctivate specific proteins or toxins in the human body. Shining light on the conjugated carbon nanotubes creates free radicals, called reactive oxygen species. It ...

conjugated in Biological Technology

New Phase 3 Data Continue to Indicate that Wyeth's Investigational 13-valent Vaccine Has the Potential to Broaden Coverage Against Pneumococcal Disease

...y regions around the world." Prevenar 13 includes the seven serotypes (4, 6B, 9V, 14, 18C, 19F and 23F) in Prevenar* (Pneumococcal Polysaccharide conjugated Vaccine, [Adsorbed]) -- the current global standard in PD prevention in infants and young children as well as six additional serotypes (1, 3, 5, 6A, 7...

Assay Designs(TM), Inc. Announces Release of First Available Product for Multiplex Analysis of Heat Shock Proteins

...ssay utilizes monoclonal antibodies or antigen affinity purified polyclonal antibodies covalently coupled to latex beads. The detection antibodies are conjugated to biotin followed by a streptavidin-PE conjugate and analyzed on a dual-laser flow cytometer. The HSP/Chaperone panel provides a sensitive, rapid an...

Mersana Reports Preliminary Phase 1 Results of XMT-1001 in Patients with Advanced Solid Tumors

...ed at American Society of Clinical Oncology (ASCO) Meeting Show Fleximer(R) conjugated Drug Is Well Tolerated with Favorable Pharmacokinetics and Prolonged Stable...ando. XMT-1001 is a broad-spectrum cytotoxic, based on camptothecin (CPT), conjugated to Mersana's biodegradable polymer platform, Fleximer(R). Ten of 37 e...

AACR 100th Annual Meeting Highlights Superior Ability of InNexus' DXL-Modified Anti-CD20 Antibody to Attach and Kill NHL With Safety Comparable to Approved Antibody Therapies in Preclinical Studies

...t affect safety even at doses 100 times that normally required for efficacy. "We have confirmed that the dose of maximally effective DXL-peptide conjugated anti-CD20 DXL625 retains the impressive safety historically seen with therapeutic anti-CD20 antibodies," Dr. Thomas Kindt, Chief Scientific Officer of...

GlycoVaxyn AG Raises CHF 25 Million in Financing Led by Edmond de Rothschild Investment Partners

...Index Ventures and Sofinnova Partners, expressed their commitment to the future of the company through significant participation in this round. conjugated vaccines provide protection against a growing range of life-threatening bacterial infections. GlycoVaxyn has developed a proprietary technology that a...

U of T chemistry discovery brings organic solar cells a step closer

...r advantage of that fact -- looked specifically at conjugated polymers which are believed to be one of the most ...es for building efficient organic solar cells. conjugated polymers are very long organic molecules that poss...scientists used ultrashort laser pulses to put the conjugated polymer into a quantum-mechanical state, whereby i...

conjugated in Biological Products

Rabbit Anti-L-isoleucine conjugated L-isoleucine Polyclonal Antibody, Unconjugated from Cell Sciences

Description: Amino-acids and Derivatives Rabbit Anti-conjugated L-isoleucine Polyclonal Antibody...
Company:Cell Sciences

Mouse Anti-Human Kappa / CD19 Antibody, FITC, PE Conjugated from Raybiotech, Inc.

Description: Dual Color Mouse anti-Human Anti-Kappa FITC/CD19 PE Class: Antibody Product Group: Immunogluobulin...
Company:Raybiotech, Inc.

Rabbit Anti-DDDDK Tag Antibody, Agarose Conjugated from MBL International

Description: Anti-DDDDK-Tag (Enterokinase Cleavage Site), Agarose Conjugate Research Focus: tag Storage: 4C Shipping Temperature: 4C...
Company:MBL International

Goat Anti-DDDDK tag Polyclonal Antibody, Fluorescein Conjugated from Abcam

Description: Goat polyclonal to DDDDK tag (FITC) ( Abpromise for all tested applications)....
Company:Abcam

Goat Anti-Human Nebraska Calf Diarrhea Virus Polyclonal Antibody, FITC Conjugated from Abcam

Description: Goat polyclonal to Nebraska Calf Diarrhea Virus (FITC) ( Abpromise for all tested applications). Antigen: Bovine (Nebraska Calf Diarrhea Virus)....
Company:Abcam

Anti-CD69 / CD3 Monoclonal Antibody, PE, PerCP Conjugated from BD Biosciences - Immunocytometry Systems

Description: CD69/CD3 50 tests...
Company:BD Biosciences - Immunocytometry Systems

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conjugated in Biological Definition

Flavin

... Riboflavin Flavin is a tricyclic heteronuclear organic ring whose biochemical source is the vitamin riboflavin . The flavin moiety is often conjugated with an adenosine diphosphate to form flavin adenine dinucleotide ( FAD ), and in other circumstances, is found as flavin mononucleotide (or FM...

Flavin

... Riboflavin Flavin is a tricyclic heteronuclear organic ring whose biochemical source is the vitamin riboflavin . The flavin moiety is often conjugated with an adenosine diphosphate to form flavin adenine dinucleotide ( FAD ), and in other circumstances, is found as flavin mononucleotide (or FM...

Immunology

...has made it an excellent tool in the detection of substances in a variety of diagnostic techniques. Antibodies specific for a desired antigen can be conjugated with a radiolabel, fluorescent label, or color-forming enzyme and are used as a "probe" to detect it. Well known applications of this include immuno...

conjugated in Biological Dictionary

Ubiquitin

...asome system, and renal diseases. ... Mouse protein-coding gene Ubc. Represented by 2568 ESTs from 329 cDNA libraries. ... Ubiquitin , becomes conjugated to proteins, marking them for selective ... Ubiquitons and Zomes ( Ubiquitin and Proteasome) ... Ubiquitin -like Proteins and Derivatives. Ubiqu...

Streptavidin

...tetramer was prepared by Richard Dixon from the ... Streptavidin -HRP - Streptavidin binds to biotin with high affinity. ... Streptavidin is conjugated with HRPC under optimal conditions. ... Streptavidin - Streptavidin antibodies from Biolegend. BioLegend develops and ... Streptavidin -FITC...

Protein array

... The array is a piece of glass on which different molecules of protein or ... on the array 's surface the conjugated ... Biomarker Discovery using Protein Arrays ... Cell-free protein array technology produces protein microarrays by performing in vitro ...

Phosphatase

...uman IgG - H&L Pre-adsorbed Polyclonal antibody, Alkaline phosphatase conjugated ... 2 Fragment Polyclonal Antibody, Alkaline Phosphatase conjugated ... Alkaline phosphatase is a broad term associated with non-specific ...

Glycoprotein

...g cassette sub-family B member 1, MDR1, and PGY1. P- glycoprotein has also recently been designated CD243 .... glycoprotein n. Any of a group of conjugated proteins having a carbohydrate as the nonprotein ... Structure of Glycoprotein and Carbohydrate Chain - Home Page ... P-glycoprotein edit ATP...

Estrogen

.... Estriol is considered the "good estrogen . ... Estrogen replacement for menopausal women has been available for more than 50 ... Premarin® and conjugated oral estrogen are the most prescribed hormonal (ERT) ... estrogen also oestrogen n. Any of several steroid hormones produced chiefly by the...