Conjugate

Pneumococcal conjugate vaccines can improve the lives of HIV-infected children

An international team of experts has published the first comprehensive review of evidence on pneumococcal conjugate vaccination (PCV) for children with HIV infection. Now available in the on-line edition of the journal Lancet Infectious Diseases, the review shows that HIV increases the risk of pne...

Wyeth's Prevenar 13* Receives First Approval

...ency to approve Prevenar 13* Valent, (Pneumococcal conjugate Vaccine 13 Valent (Diphtheria CRM(197) Protein)) f...the broadest serotype coverage of any pneumococcal conjugate vaccine. Prevenar 13 contains 13 serotypes, seven... or Prevenar 13 Valent with any other pneumococcal conjugate vaccine that does not contain protein carrier CRM(...

Hard To Treat Diseases (HTDS.PK) Agreement With 2nd Largest Vaccine Manufacturer in China Yunnan Walvax Biotech Co

...tech Co., Ltd for the Haemophilus influenza type b conjugate vaccine. Yunnan Walvax Biotech Co. Ltd is the seco...ggest manufacturer of Haemophilus influenza type b conjugate vaccine in China. This agreement / arrangement now...national marketing of Haemophilus influenza type b conjugate vaccine in the global market. In other corporate...

Fewer Shots Could Still Protect Kids From Pneumonia

...he pneumococcal vaccine can protect infants against pneumonia and other infections. The current recommended dose schedule for 7-valent pneumococcal conjugate vaccine (PCV-7) consists of three primary doses before the age of 6 months, followed by a booster vaccination in the second year of life (3 + 1-dose s...

Supply of Key Children's Vaccine Almost Back to Normal

...s concerning," Michael Jackson, an epidemiologist with the CDC, said in November. The shortfall was caused by Merck's recall of certain lots of Hib conjugate vaccine, followed by a suspension of production beginning in December 2007. At the time, Merck spokeswoman Amy Rose said that problems with the vaccin...

Hard to Treat Diseases, Inc. (HTDS) Finalizes Agreement with Yunnan Walvax Biotech

...Ltd on the issue of Haemophilus influenza type "B" conjugate vaccine. Under the terms of the agreement Mel...tional marketing of Haemophilus influenza type "B" conjugate vaccine in the global market. HTDS intends to...ggest manufacturer of Haemophilus influenza type b conjugate vaccine in China. Safe Harbor Statement ...

Conjugate in Medical Technology

Wyeth Applauds Six Countries Across Europe, and the Middle East, That Recently Announced the Inclusion of the 7-Valent Pneumococcal Conjugate Vaccine (PCV7) in Their Immunization Schedules

MAIDENHEAD, England, July 8 /PRNewswire-FirstCall/ -- - PREVENAR Vaccine to Help Protect Children Against the Leading Vaccine-Preventable Cause of Death in Young Children Wyeth applauds the countries of Cyprus, Hungary, the Kingdom of Bahrain, Republic of Ireland, Slovak Republic and Swede...

Wyeth Receives FDA Fast Track Designation for its 13-valent Pneumococcal Conjugate Vaccine for Infants and Toddlers

COLLEGEVILLE, Pa., May 29 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to the Company's investigational 13-valent pneumococcal conjugate vaccine for infant...

Semafore's PI3 Kinase Inhibitor SF1126 is a Vascular Targeted Conjugate in Phase I Clinical Trials in Solid Tumors and Multiple Myeloma

SAN DIEGO, April 14 /PRNewswire/ -- Semafore Pharmaceuticals Inc. announced today on the occasion of a poster presentation at the 2008 AACR Annual Meeting that its integrin-targeted PI3 kinase inhibitor, SF1126, was shown to cause significant tumor regression in combination with rapamycin in a...

Nektar Therapeutics Reports Second Quarter 2009 Financial Results

...strategy to focus on developing proprietary drugs with our advanced polymer conjugate technology." Research and development expense was $24.2 million in t...al opioid antagonist that combines Nektar's advanced small molecule polymer conjugate technology platform with naloxol, a derivative of the opioid-antagonist dru...

CuraGen Announces Expansion of CR011-vcMMAE Phase II Trial in Advanced Breast Cancer

...en anticipates presenting updated results from this study during the second half of 2009. About CR011-vcMMAE CR011-vcMMAE is an antibody-drug conjugate (ADC) being developed by CuraGen that consists of a fully-human monoclonal antibody, CR011, linked to a potent cell-killing drug, monomethyl-auristati...

Paclitaxel Poliglumex (OPAXIO(TM)) Added to Cisplatin and Radiation Produces 45% Pathologic Complete Remissions in Patients With Esophageal Cancer

...f 1.5 to 2.0, OPAXIO increases tumor specific radiation cell kill by a factor of 7.2 to 8.4 -fold (Milas Luka et al , Poly(L-glutamic acid)-paclitaxel conjugate is a potent enhancer of tumor radiocurability , Int'l J. Radiat. Oncol. Biol. Phys. 55(3), 707-12 (2003)). The Brown University Oncology Group ...

Conjugate in Medical Products

Androstanediol Glucuronide RIA Test

Description:... Androstanediol glucuronide (3alpha-diol G) is the glucuronide conjugate of 3alpha-androstanediol, a major metabolite of dihydrotestosterone (DHT) [1,2]. 3alpha-diol G has strong androgenic activity estimated at 75% of the ...
Company:Diagnostic Systems Laboratories, Inc.

Androstanediol Glucuronide EIA Test

Description:... Androstanediol glucuronide (3alpha-diol G) is the glucuronide conjugate of 3alpha-androstanediol, a major metabolite of dihydrotestosterone (DHT) [1,2]. 3alpha-diol G has strong androgenic activity estimated at 75% of the ...
Company:Diagnostic Systems Laboratories, Inc.

Salmonella Typhi Antigen - Rapid Test

Description:...Quant S. typhi rapid test is a qualitative one step immunochromatographic assay. The test employs a conation of monoclonal antibody/colloidal gold dye conjugate and a polyclonal antibody immobilized on the solid phase. This will selectively identify S. typhi antigen associated Salmonella typhi (typhoid) infect...
Company:Bio-Quant, Inc.

Quidel CIC-C1q EIA

Description:...ncubation, unbound material is removed in a washing step and a ready to use conjugate (goat anti-human Ig-HRP) is added. After a second incubation, unbound conjugate is washed away....
Company:Quidel Corporation

CIC-C1q ELISA

Description:...and neoplastic diseases. The principle of the assay is based on C1q coated microtiter wells binding CIC from the patients serum or plasma. An enzyme conjugate recognizes the Fc region of the bound complex....
Company:Buhlmann Laboratories AG

Follicle Stimulating Hormone (FSH) Enzyme Immunoassay Test Kit

Description:...s mouse monoclonal anti-FSH for solid phase (microtiter wells) immobilization, and sheep anti-alpha FSH in the antibody-enzyme (horseradish eroxidase) conjugate solution....
Company:BioCheck, Inc.

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Conjugate in Biological News

Biodegradable polymers show promise for improving treatment of acute inflammatory diseases

...loped a method of simply immobilizing the protein on the surface of the microparticles." The researchers incorporated a nitrilotriacetic acid-lipid conjugate into the polyketal. In a one-step procedure, they mixed the microparticles with the proteins and centrifuged them. That immobilized the proteins on th...

AIBS to cohost symposium on evolution, disease and human health

...ty (natural and vaccine induced), antimicrobial agents, and other pressures. A central question in his research is whether widespread use in humans of conjugate vaccines, against a subset of serotypes will result in increased carriage of nonvaccine serotypes (serotype replacement), and if so, what the public h...

'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance

...otential of the basic work done in his lab that he, along with professor of oncology Richard Burgess, started a company called ConjuGon - "because you conjugate and it's gone!" -- to develop the technology and ultimately bring it to human trials, which are currently planned for 2007 or 2008. A patent for his ...

Malaria vaccine prompts victims' immune system to eliminate parasite from mosquitoes

...ademy of Sciences. The vaccine was developed with conjugate technology, which joins or "conjugates" molecules ...immune system can recognize easily. Primed by the conjugate vaccine, the immune system begins making antibodie... the immune system would fail to detect. "With conjugate technology, NIH researchers have developed effecti...

Berkeley researchers lay groundwork for cell version of DNA chip

...rancis and Bertozzi, used the Staudinger ligation to create a phosphine-DNA conjugate that makes it possible for the DNA to adhere to a cell's surface. The phosphine-DNA conjugate provides an outer layer of adhesion that is independent of the cell's natur...

Hospitalizations because of chicken pox down dramatically since implementation of vaccine

...e attributable to varicella. As with other childhood and adolescent vaccines that have recently been recommended (e.g., pneumococcal and meningococcal conjugate vaccines), indirect cost savings with varicella vaccine were expected to be larger than savings in direct medical costs." "To maximize the benefits...

Conjugate in Biological Technology

Cyprus and Ireland Add Wyeth's 7-Valent Pneumococcal Conjugate Vaccine (PCV7) to Their National Immunisation Schedules

MAIDENHEAD, England, September 4 /PRNewswire-FirstCall/ -- - Prevenar Vaccine to Help Protect Children Against the Leading Vaccine-Preventable Cause of Death in Young Children Worldwide Wyeth today announced that Cyprus and the Republic of Ireland have initiated national immunisation progr...

SAFC Supports Potent API Conjugate Manufacturing With New St. Louis Production Suite

ST. LOUIS, Oct. 2 /PRNewswire-FirstCall/ -- SAFC(R), a member of the Sigma-Aldrich(TM) Group (Nasdaq: SIAL ), has announced its plans to begin construction of a new cGMP potent active pharmaceutical ingredients (APIs) conjugation suite at its Pharma sector's St. Louis manufacturing campus. Th...

Nektar Therapeutics to Present at the BMO Capital Markets 9th Annual Focus on Healthcare Conference in New York City

... positive Phase 2 results for Oral NKTR-118, its proprietary novel peripheral opioid antagonist that combines Nektar's advanced small molecule polymer conjugate technology platform with naloxol, a derivative of the opioid-antagonist drug, naloxone. Nektar's technology has been shown to increase oral bioavailab...

Nektar to Announce Financial Results for the Second Quarter of 2009 on Tuesday, August 4, 2009, After Close of U.S.-Based Financial Markets

... positive Phase 2 results for Oral NKTR-118, its proprietary novel peripheral opioid antagonist that combines Nektar's advanced small molecule polymer conjugate technology platform with naloxol, a derivative of the opioid-antagonist drug, naloxone. Nektar's technology has been shown to increase oral bioavailab...

CuraGen Reports Second Quarter 2009 Financial Results

... month periods ended June 30, 2009, respectively. CuraGen is continuing to enroll patients in clinical trials of CR011-vcMMAE, an antibody-drug conjugate that targets GPNMB. "We continue to be very positive about the development opportunities for CR011 in breast cancer and melanoma," commented Dr. Timot...

Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply

... and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b conjugate [Tetanus Toxoid Conjugate] Vaccine) and ActHIB(R) (Haemophilus b conjugate Vaccine [Tetanus Toxoid Conjugate]). "Sanofi Pasteur has accelerated p...

Conjugate in Biological Products

Rabbit Anti-D-TYROSINE CONJUGATE Polyclonal Antibody, Unconjugated from AbD Serotec

Description: RABBIT ANTI D-TYROSINE CONJUGATE...
Company:AbD Serotec

Rabbit Anti-NO-TRYPTOPHAN CONJUGATE Polyclonal Antibody, Unconjugated from AbD Serotec

Description: ANTI NO-TRYPTOPHAN CONJUGATE...
Company:AbD Serotec

Mouse Anti-L-DIHYDROXYPHENYLALANINE (L-DOPA) CONJUGATE Monoclonal Antibody, Unconjugated from AbD Serotec

Description: ANTI L-DOPA...
Company:AbD Serotec

Rabbit Anti-5-HYDROXYTRYPTOPHAN CONJUGATE Polyclonal Antibody, Unconjugated from AbD Serotec

Description: ANTI 5-HYDROXYTRYPTOPHAN CONJ....
Company:AbD Serotec

5x MONO-POLY CONJUGATE DILUENT from AbD Serotec

Description: Form: Concentrated Applications: ELISA...
Company:AbD Serotec

Panomer 9 random oligodeoxynucleotide, Alexa Fluor 647 conjugate from Molecular Probes (Invitrogen)

Description: Panomer 9 oligodeoxynucleotides are random primers that are labeled at the 5' end with our proprietary Alexa Fluor dyes and they are useful for assessing microarray spot morphology, hybridization potential and channel bleedthrough on DNA microarrays....
Company:Molecular Probes (Invitrogen)

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Conjugate in Biological Definition

Amine

...ne CH 3 -CH 2 -CH 2 -CH 2 -NH 2 0.15·10 -10 M Like ammonia, amines act as bases and are reasonably strong (see table for examples of conjugate acid K a values). The nitrogen atom has a lone electron pair available which can accept a H + ion to bond to the nitrogen forming a positive substi...

Monoclonal antibody

... or other active conjugate; it is also possible to design bispecific antibodies that can bind with their Fab regions both to target antigen and to a conjugate or effector cell. In fact every intact antibody can bind to cell receptors or other proteins, however with their Fc region. The picture below shows al...

Vaccine

...ain called " BCG "; it is used in the United States very infrequently. A number of innovative vaccines are also in development and also in use: conjugate - certain bacteria have outer coats that inexperienced immune systems don't recognize. By linking these unknown outer coats to proteins and toxins th...

Conjugate in Biological Dictionary

Reducing agent

...Reducing Agents ... Oxalic acid, on the other hand, is a reducing agent in this reaction. ... Oxidizing Agents and Reducing Agents ... conjugate Oxidizing Agent / Reducing Agent Pairs. Metals act as reducing agents in their chemical reactions. ... Defines oxidation and reduction ...

Phosphate ion

... carries a negative three formal charge and is the conjugate ... In weakly-acid conditions, the dihydrogen ph... carries a negative three formal charge and is the conjugate ... Lithium iron phosphate battery Battery sp... carries a negative three formal charge and is the conjugate ... The phosphate ion carries a negative th...

Hela cell

... Hela Cell tubulin may be used in all situations where previously bovine brain ... HeLa cell tubulin is also available as a biotinylated conjugate for ... GeneXplore the Human Cell Cycle data from Hela cells . Search. Search the complete dataset ... data, and interactively explore the ce...

Conjugation tube

...lament put out a conjugation tube ... directly into the centrifuge tube used previously to collect the. antibody sample. Conjugation ... conjugate in a centrifugation tube (Component L). Do not ... conjugation synonyms. conjugation usage examples and ... conjugation tube . conjugatio...

Buffer

...ution is an aqueous solution consisting of a mixture of a weak acid and its conjugate base or a weak base and its conjugate acid. It has the property that the pH of the solution changes very little w...