Compounds

First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers

Two compounds that zero in on cancer cells spreading throughout the body, while ignoring primary tumor cells, could someday give doctors a whole new weapon in the fight against tough-to-treat metastatic disease, according to Weill Medical College of Cornell University researchers. The compounds, called synthetic migrastatin analogues, prevented 91 to 99 percent of metastatic breast cancer...

Researchers discover chemical compounds that affect plant growth

A team of biologists from the University of California, Riverside has used chemical genomics to identify novel compounds that affect the ability of plants to alter their direction of growth in response to gravity, a phenomenon known as gravitropism. The researchers screened a library of 10,000 small molecules, the practice is known as chemical genomics, to identify those that could positiv...

Compounds in plastic packaging act as environmental estrogens altering breast genes

Compounds found in plastic products used to wrap or contain food and beverages have aroused concerns as possible cancer-causing agents because they can sometimes leach out of the plastic and migrate into the food, especially after heating or when the plastic is old or scratched. In two studies funded by the National Institute of Environmental Health Sciences, researchers at Fox Chase Cancer Cente...

Bacterial genome sheds light on synthesizing cancer-fighting compounds

Sea squirts around the world are breathing a sigh of relief, as they no longer run the risk of being harvested for their natural disease-fighting substances. Scientists recently discovered that the bacterium Prochloron didemnii, which lives symbiotically inside the sea squirt, actually produces the desired patellamides, compounds that may one day be used in cancer treatment. Despite decade...

Scientists discover the body's marijuana-like compounds are crucial for stress-induced pain relief

new study shows, for the first time, that the release of the body's own marijuana-like compounds is crucial to stress-induced analgesia ?the body's way of initially shielding pain after a serious injury. The work, led by scientists at the University of Georgia and the University of California, Irvine, may yield a target for new drug therapies that will completely bypass the current argume...

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Isolation and Characterization of Anti-Viral Nucleoside Compounds from the Chinese Herb Taraxacum Mongolicum

Characterization of nucleotide and nucleoside analogs from Taraxacum mongolicum, a Chinese medicinal herb was achieved for the first time using liquid chromatography tandem mass spectrometry (LC/MS/MS). The active ingredients in the herb were characterized using nucleotide and nucleoside standards with product and precursor scans of tandem mass spectrometry. The nucleoside analogs wer...

TSKgel ODS-100Z and TSKgel ODS-100V column series provides a universal solution for the analysis of samples containing acidic, basic, polar & non-polar compounds

Using high purity Type B silica, Tosoh has introduced two new columns with differing surface treatment procedures and carbon content levels to provide unique selectivities for a wide range of sample types. In recent years, many new octad...

Compounds at Medicine News

Five New Anti-Inflammatory Compounds Produced By Indian Scientists

Five new anti-inflammatory compounds (fight against inflammation) that are 10, 000 times more potent than the most commonly used drugs such as nimusulide and aspirin have been developed and patented by Indian researchers.// Researchers from the All India Institute of Medical Sciences (AIIMS), situated in New Delhi, India, have carried out the work. "These compounds are about 10,000 ti...

Brain cells protected by new compounds

Pharmacists have made compounds that can terminate the natural death of brain cells and could treat an extent of neurodegenerative diseases. The protein p53 plays// an important role in getting damaged cells to kill themselves. Its known to be important in cancer - where defective p53 genes allow cancer cells to grow, instead of dying off. Now researchers at the National Institutes of Health are...

Breathing Cancer Causing Compounds During Pregnancy Found To Affect Offspring

Based on findings of a recent study researchers have linked breathing cancer-causing compounds during pregnancy // to an increased risk of childhood cancer among offspring. They also believe that nearly all childhood cancers can probably be traced back to a mother’s inhalation of noxious substances. The study compared a chemical emissions map with all children age 15 and younger who died...

Body compounds can protect you against pain

The human body can release chemical compounds like marijuana that can help the body to kill its own pain in case of pain from severe trauma // like accidents. Scientists have always known that sudden shock, like wounds from gun shot, or accidents causing severe damage to body, delays the body’s pain due to the trauma. This is known as stress-induced analgesia, or body’s reaction to sh...

Compounds Found In The Vegetable Broccoli Could Have Anti-Cancer Properties

Studies in the past have shown that certain compounds in the vegetable broccoli, are known to halt the growth of breast, prostate, colon and stomach cancer cells and also appear to slow the progress of bladder cancer. In a more recent study researchers //say they have identified that isothiocyanates hindered the growth of bladder cancer cells in the lab, with the most profound effect on the most...

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Six Abstracts Featuring Exelixis Compounds Accepted At ASCO Conference

- Phase I data from XL880, Phase II data from XL999 studiesscheduled for presentation during oral, poster sessions - SOUTH SAN FRANCISCO, May 30, 2007 /PRNewswire-FirstCall/ --Exelixis, Inc. announced today that data from clinical trials ofthe company's investigational compounds XL880 and XL999 will bepresented at the 2007 American Society of Clinical Oncology AnnualMeeting (ASCO), which...

ImmunoGen, Inc. Announces Clinical Findings for Three TAP Compounds for Solid Tumors Are to be Reported at ASCO

CAMBRIDGE, Mass.--(BUSINESS WIRE)--May 24, 2007 - ImmunoGen, Inc.(Nasdaq: IMGN), a biopharmaceutical company that develops targetedanticancer therapeutics using its Tumor-Activated Prodrug (TAP)technology, today announced that clinical findings for threedifferent TAP compounds for the treatment of solid tumors are to bereported at the 43rd American Society of Clinical Oncology (ASCO)Annual...

Pharmacyclics Announces Presentations on Its Novel and Selective HDAC and Bruton's Tyrosine Kinase Inhibitor Compounds

SUNNYVALE, Calif., April 11, 2007 /PRNewswire-FirstCall/ --Pharmacyclics, Inc. announced today multiple presentationsregarding its novel histone deacetylase (HDAC) inhibitor andBruton's tyrosine kinase inhibitor compounds. The presentationswill take place at the American Association for Cancer Research(AACR) 2007 Annual Meeting being held April 14-18, 2007, at the LosAngeles Convention C...

Scientific Results Presented At ECCMID Demonstrate Well- Differentiated Profile of Basilea's Two Phase III Anti- infective Compounds

BASEL, Switzerland, April 3, 2007 (PRIME NEWSWIRE) -- New datapresented at ECCMID highlight the microbiological andpharmacokinetic profiles of Basilea's (SWX:BSLN) two late-stagedrug candidates ceftobiprole and isavuconazole. Studies reportedboth for ceftobiprole, the first anti-MRSA broad-spectrumcephalosporin in late-stage development, and for isavuconazole, anovel azole for the treatm...

EntreMed Presents Mechanism Data for Its Three Lead Oncology Compounds

Multiple Mechanisms for Panzem NCD, MKC-1, and ENMD-1198Highlighted at Oncology Drug Discovery Conference ROCKVILLE, Md., March 26, 2007 /PRNewswire-FirstCall/ --EntreMed, Inc., a clinical-stage pharmaceutical company developingtherapeutics for the treatment of cancer and inflammatory diseases,today announced the presentation of comparative mechanism of actiondata for its three lead clini...