Molecular machine may lead to new drugs to combat human diseases
The crystallized form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients. Purdue University researchers froze one of these molecular machines, which are chemical complexes known as a Group I intron, at mid-point in its work cycle. When frozen...A bacterial genome reveals new targets to combat infectious disease
More than a billion people are at risk for infection with filarial nematodes, parasites that cause elephantiasis, African river blindness, and other debilitating diseases in more than 150 million people worldwide. The nematodes themselves play host to bacteria that live within their cells, but in this case, the relationship is classic mutualism, with each benefiting from the other. Indeed, the Wo...Light therapy may combat fungal infections, new evidence suggests
A newly discovered mechanism by which an infectious fungus perceives light also plays an important role in its virulence, according to Howard Hughes Medical Institute investigators at Duke University Medical Center. The findings suggest that changes in light following fungal invasion of the human body may be an important and previously overlooked cue that sparks infection, the researchers said.</...New polysaccharide may help combat multidrug resistance in cancer
In a recent study published in the Journal of Biological Chemistry, scientists report that a molecule previously thought to play a purely structural and inert role in cells is actually involved in multidrug resistance in cancer. Using antagonists for this molecule, the researchers were able to sensitize drug resistant breast cancer cells to chemotherapeutic drug treatment. The research ap...Male Combat Veterans Rank High In Heart Disease Risk
Men who fought in World War II, the Korean War, and the Vietnam War are more likely to be heavy drinkers, heavy smokers and obese than men who are non-combat veterans or non-veterans, according to a study presented at the American Heart Association's 45th annual Conference of Cardiovascular Disease, Epidemiology and Prevention. "Combat veterans were four times more likely to be heavy drin...Combat RNase Contamination in the Lab
Trace amounts of ribonuclease (RNase) contamination can sabotage experiments. Since RNases are ubiquitous in the laboratory environment--on your skin, in the air, on anything touched by bare hands or on anything left open to the air--it is important to make an effort to prevent...While schools combat low tech enrollment, are businesses contributing to IT workforce woes?
Judging by the growing number of technology activ...Thompson's HHS legacy will include efforts to combat disease in Africa
Even if former Wisconsin Gov. Tommy Thompson skips a second term i...Mirus receives $1.26 million SBIR grant to combat anemia
, a gene therapy researcher, announced on Wednesday that it will receive a $1.26 million Phase II Small Business Innovation Research grant from the National Institutes...NameProtect and MasterCard unite to combat online fraud, phishing
MADISON, Wis. Under the arrangement, NameProtect...New Vaccines To Combat Rotavirus
Rotavirus which causes severe diarrhea can be combated with two new vaccines, according to clinical trials. The New England Journal of Medicine has published this report.// The symptoms can be reduced by as much as by between 85% to 100%. The affliction affects children in large numbers. Experts say the unqualified success of two drugs in these larger trials, without negative side ef...ICMR to Set up Laboratories to Combat Bird Flu
The Director General of The Indian Council of Medical Research has announced the installation of three US-funded bio-safety level laboratories by ICMR in Chennai// , New Delhi, Kolkata and Pune to efficiently combat any avian flu outbreak An international consultancy firm will be in charge of setting up the centers at costs beginning from Rs 15 crores to Rs 20 crores, with an action pl...