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Colorectal in Medical News

Cost-effectiveness of cetuximab in metastatic colorectal cancer

From a health-care system perspective, it may be more efficient to use the drug cetuximab only in colorectal cancer patients whose tumors have a wild-type KRAS gene, according to a study published online August 7 in the Journal of the National Cancer Institute . Earlier, patients whose tumors ...

Genetic testing may be valuable in treating colorectal cancer

NEW YORK (July 27, 2009) -- For the 29,000 patients in the United States with metastatic colorectal cancer, chemotherapy with irinotecan is a standard treatment that has been shown to improve survival. But for more than one in 10 of these patients, a variation in their DNA means that this treatmen...

New piece found in colorectal cancer puzzle

Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the expression of inhibitors of the enzyme with malignant cellular beh...

Study Finds Possible Genetic Indicator of Colorectal Cancer

If perfected, screening method could make disease detection easier, experts say THURSDAY, June 18 (HealthDay News) -- Scientists say they may be moving closer to developing a genetic test for colorectal cancer that could indicate who needs a more advanced colonoscopy screening. In a...

Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer

Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute . In the study, Manon van Engeland, Ph.D., of...

New American College of Surgeons risk calculator determines colorectal surgery risk

CHICAGO (June 11, 2009) New research published in the June issue of the Journal of the American College of Surgeons shows that a risk calculator developed by the American College of Surgeons (ACS) can help surgeons provide patients with more detailed and accurate preoperative information about ...

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Colorectal in Medical Technology

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

THOUSAND OAKS, Calif., Aug. 6 /PRNewswire-FirstCall/ -- Amgen (Nasdaq: AMGN ) today announced that Vectibix((R)) (panitumumab), administered in combination with FOLFOX (an oxaliplatin-based chemotherapy), significantly prolonged progression-free survival (PFS) compared with F...

ARUP Laboratories Applauds FDA's Decision on the Value of KRAS-Mutation Testing in Colorectal Cancer

SALT LAKE CITY, Aug. 4 /PRNewswire/ -- ARUP Laboratories , a national clinical and anatomic pathology reference laboratory and a leader in innovative laboratory research and development, supports the U.S. Food and Drug Administration's (FDA) decision to put KRAS on the label of...

Poniard Pharmaceuticals Announces Progression-Free Survival Data From Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer

- New Progression-Free Survival, Disease Control and Neurotoxicity Data To Be Presented at 2009 ASCO Annual Meeting Continue to Support Picoplatin as a Neuropathy-Sparing Alternative to Oxaliplatin for First-Line Treatment of Colorectal Cancer - - Poniard Management Team to Host Analyst and I...

Clinical Genomics Continues Progress in Developing Biomarker Portfolio for Colorectal Cancer Testing

SYDNEY, April 29 /PRNewswire/ -- Clinical Genomics Pty Ltd, an Australian biotechnology company, announced today that Quest Diagnostics Incorporated, the world's leading provider of diagnostic testing, information and services, has agreed to provide milestone payments over the next two years t...

Micromet Presents Preclinical Data Showing Activity of Erbitux and Vectibix Based BiTE Antibodies against KRAS- and BRAF-mutated Human Colorectal Cancer Cells

Study Presented at 2009 AACR Meeting Highlights Potential Therapeutic Approach to Treat Patients Unresponsive to Erbitux and Vectibix DENVER, April 22 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI ), a biopharmaceutical company developing novel, proprietary antibodies for the treat...

Micromet Has Started a New Phase 2 Trial with Adecatumumab in Colorectal Cancer Patients

Randomized, Controlled, Multicenter Trial Will Test Ability of Adecatumumab to Prolong Disease Free Survival in High Risk Patients with Liver Metastases BETHESDA, Md., March 23 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI ), a biopharmaceutical company developing novel, propriet...

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Colorectal in Medical Products

Microsatellite Instability (MSI) for Hereditary Nonpolyposis Colorectal Cancer

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Pocket Guide to Colorectal Cancer Drugs and Treatment

Description: Focuses primarily on the drugs used for treatment and symptom management for colorectal cancer....
Company:Skyscape, Inc.

Hemoccult ICT

Description:...nd polyps than traditional guaiac-based FOBTs. Because of its superior specificity for lower GI bleeding, Hemoccult ICT is an ideal screening tool for colorectal cancer (CRC), and this specificity also reduces the number of false positive test results. Safe and non-invasive, Hemoccult ICT is very patient friend...
Company:Beckman Coulter, Inc.

Hemoccult ICT Fecal Occult Blood Test

Description:...nd polyps than traditional guaiac-based FOBTs. Because of its superior specificity for lower GI bleeding, Hemoccult ICT is an ideal screening tool for colorectal cancer (CRC), and this specificity also reduces the number of false positive test results. Safe and non-invasive, Hemoccult ICT is very patient friend...
Company:Beckman Coulter, Inc

VALTRAC™ Sizer Device

Description:...r Device for use with VALTRAC™ Devices (Single Use Biofragmentable Anastomosis Ring). The Purstring™ Device is indicated in intestinal, colorectal and esophageal surgery for the placement of purse string sutures and is intended for use with VALTRAC™ and EEA™ Instruments....
Company:Autosuture

VALTRAC™ Reusable Purstring Device

Description:...g Device for use with VALTRAC™ Devices (Single Use Biofragmentable Anastomosis Ring). The Purstring™ Device is indicated in intestinal, colorectal and esophageal surgery for the placement of purse string sutures and is intended for use with VALTRAC™ and EEA™ Instruments....
Company:Autosuture
Colorectal in Medical Definition

European Prospective Investigation into Cancer and Nutrition

... analyses are focusing particularly on stomach , colorectal , breast , prostate and lung cancers. The dif...ion of fibre, fish, milk and cheese reduce risk of colorectal cancer, while red and processed meat increase risk... al . Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation i...

Full-body scan

...er JA, Puckett ML, Hildebrandt HA, Wong RK, Nugent PA, Mysliwiec PA, Schindler WR. (Mar 2003). "Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults.". New England Journal of Medicine 349 (23): 2191 - 2200. PMID 14657426 . ^ Lauenstein TC, Semelka RC...

Pathology

... Colon Diarrhea - Appendicitis - Diverticulitis - Diverticulosis - IBD ( Crohn's , Ulcerative colitis ) - IBS - Constipation - colorectal cancer - Hirschsprung's - Pseudomembranous colitis Hernia Inguinal - Femoral - Umbilical - Incisional - Diaphragmatic ...
Colorectal in Medical Dictionary

Colorectal polyps

... A colorectal polyp is a polyp (fleshy growth) occurring on the lining of the colon or rectum. Untreated colorectal polyps can develop into colorectal cancer. A ...

Vitamin D

... from both deficiency and large doses. Vitamin D3: Higher Doses Reduce Risk of Common Health Concerns. By ... Optimal Vitamin D status for colorectal cancer prevention: a quantitative meta analysis. ... Krispin Sullivan, CN, describes the miraculous health benefits of adequate Vitamin D in...

Sigmoidoscopy

... A brief description of sigmoidoscopy , a procedure used to screen for colorectal cancer. ... Sigmoidoscopy (SIG-moy-DAH-skuh-pee) enables the physician ...r a short and rigid ... Sigmoidoscopy is used most often in screening for colorectal cancer or to ... SIGMOIDOSCOPY OVERVIEW A flexible sigmoidoscopy ...

Rectal cancer

... colorectal cancer , also called colon cancer or large b...he risk of rectal cancer . ... Get in-depth colorectal cancer information here on including ... Rectal...ng. 11. Ileostomy. 12. Barium Enema. Understanding colorectal Cancer - Symptoms ... More about Rectal C...

Rectal abscess

...Prolapse ... An abscess may be deep in the rectum or close to the opening of the anus. ... Offering Comprehensive Proctology, Colon, Rectal , colorectal & Anal Services. ... Anal Rectal Abscess & Fistula. Anal Abscess (Anorectal Abscess ) ... A rectal abscess is caused by a bact...

Radiation enteritis

...ts only a short time, it is called acute radiation enteritis . ... colorectal cancer - The Cleveland Clinic Digestive Disease Center; colorectal surgery, gastroenterology, stomach disorders and other digestive diseases...
Colorectal in Biological News

Study finds colorectal cancer rates increasing worldwide

ATLANTAJune 9, 2009A new study finds colorectal cancer incidence rates for both males and females increased in 27 of 51 countries worldwide between 1983 and 2002, and points to increasing Westernization as being a likely culprit. The rise was seen primarily in economically transitioning countries ...

Rural areas able to increase screening capacity for colorectal cancer

CAREFREE, A.Z. - Arizona has the ability to expand colorectal cancer screening capacity; this potential increase was more pronounced in rural as compared to urban regions, according to data presented at the American Association for Cancer Research conference on the Science of Cancer Health Dispari...

Hormone therapy associated with reduced colorectal cancer risk

PHILADELPHIA The combination of estrogen plus progestin, which women stopped taking in droves following the news that it may increase their risk of breast cancer, may decrease their risk of colorectal cancer, according to a report published in the January issue of Cancer Epidemiology, Biomarkers...

Scientists discover major genetic cause of colorectal cancer

CHICAGO -- About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases. Scientists at Northwestern University's Feinberg School of Medicine and colleagues have ...

Curry-derived molecules might be too spicy for colorectal cancers

SINGAPORE -- Curcumin, the yellowish component of turmeric that gives curry its flavor, has long been noted for its potential anti-cancer properties. Researchers from Tohoku University in Sendai, Japan, report on an apparent improvement upon nature: two molecular analogues of curcumin that demon...

Interleukin-8, key marker for colorectal cancer treatment

Colorectal cancer (CRC) is currently one of the three most frequent malignancies in Western industrial nations. Although the 5-year survival rate for patients with early stage and local CRC approaches nearly 90%, survival is dramatically decreased by local recurrence and the development of distant...
Colorectal in Biological Technology

Laboratory Test May Predict Effectiveness of ERBITUX(R) for Individual Colorectal Cancer Patients

Data Presented Today at American Society of Clinical Oncology ORLANDO, Fla., June 1 /PRNewswire/ -- Precision Therapeutics, Inc. today presented data demonstrating the use of ChemoFX(R), a chemosensitivity assay, to predict the effectiveness of cetuximab (ERBITUX(R)) on the colorectal cancer ...

Agendia to Present Multiple Predictive and Prognostic Studies on Breast and Colorectal Cancers at ASCO Annual Meeting

HUNTINGTON BEACH, California and AMSTERDAM, May 21 /PRNewswire/ -- Agendia, a world leader in molecular cancer diagnostics, today announced that leading researchers from Agendia, the University of California San Francisco and the Netherlands Cancer Institute will present data from multiple s...

Beyond associations: Colorectal cancer culprit found

Genetics plays a key role in determining risk for colorectal cancer, the second leading cause of cancer-related deaths in the United States. Several common genetic markers have been found to be associated with the disease, but finding the biological events that lead to cancer can be much more dif...

Micromet Presents Data at AACR Meeting Showing Elimination of Colorectal Cancer Stem Cells by BiTE Antibody MT110

DENVER , April 22 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI ), a biopharmaceutical company developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases, yesterday presented data at the annual meeting of the American Association for Canc...

Poniard Pharmaceuticals Presents Final Results of Phase 1 Study of Picoplatin in Patients with Metastatic Colorectal Cancer

- Safety and Tumor Response Data from Dose-Escalation Study Presented at American Association for Cancer Research's 100th Annual Meeting 2009 - SOUTH SAN FRANCISCO, Calif. and DENVER, April 21 /PRNewswire-FirstCall/ -- Poniard Pharmaceuticals, Inc. (Nasdaq: PARD ), a biopharmaceutical com...

ScreenCancer Adds InSure(R) FIT(TM) Colorectal Cancer Screening Test to European Cancer Screening Program

OSLO, Norway, February 26 /PRNewswire/ -- ScreenCancer AS, a Norwegian company offering cancer screening management services to employers, insurance companies and individuals, today announced that it has added the InSure(R) FIT(TM) take-at-home colorectal cancer screening test to its European ...
Colorectal in Biological Products

Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex

Description:...CDX2-88 reacts with a conserved epitope of the 40kD CDX2 protein localized in the nucleus. It exclusively marks nuclei of colonic epithelial cells and colorectal cancers on formalin-fixed, paraffin-embedded tissue sections. Therefore clone CDX2-88 may be used in identifying metastatic colon carcinoma....
Company:BioGenex

microRNA Expression Profiling - Comprehensive Service from LC Sciences

Description:...s, J.M., He, Y., Leary, R.J., Pagliarini, R., Diaz, L.A., Jr., Sjoblom, T., Barad, O., Bentwich, Z., Szafranska, A.E., Labourier, E. et al. (2006) The colorectal microRNAome. Proc Natl Acad Sci USA 103, 3687-3692....
Company:LC Sciences

Human / Mouse / Rat Blood Vessels (CD31 / Von Willebrand Factor (vWF)) IHC staining Kit from CHEMICON

Description:...le for the identification of angiogenesis in several types of malignancies such as lung (Giatromanolaki et al., 1996), breast (Horak et al., 1992) and colorectal cancer (Takebayashi et al., 1996). CHEMICONs monoclonal antibody to CD31 is very specific for the staining of vascular endothelial cells in normal and...
Company:CHEMICON
Colorectal in Biological Definition

Cancer

...a , multiple myeloma , brain tumor , breast cancer , cervical cancer , colorectal cancer - in the colon , rectum , anus , or appendix , esophageal canc... test the following: acupuncture to reduce the symptoms of advanced colorectal cancer , combination chemotherapy plus radiation therapy with or wit...
Colorectal in Biological Dictionary

Wildtype

...ffering from the wildtype . ... Findings from three studies demonstrate the increased efficacy of Erbitux® (cetuximab) in patients with metastatic colorectal cancer (mCRC) who have a wild-type ... Britannica online encyclopedia article on wild type (genetics), ...code. ... Aspects of the topic wil...

Small intestine

...l bowel, is a cancer of the small intestine . It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer and colorectal cancer. The small intestine is a long coiled tube located in the abdominal cavity. ... In the small intestine , the epithelial cells cov...

Serosa

...ore characters, a list of up to 10 suggestions will ... serosa (seh-ROH-suh) ... ... blue into the mucosa or serosa immediately adjacent to a colorectal cancer ... isosulfan blue into peritumor serosa upon intraoperative identification of the ... In anatomy, a serous membrane (or serosa ) is a ...

Screening

...ert-reviewed information summary about tests used to detect or screen for colorectal cancer. ... Studies show that screening for colorectal cancer helps ... ... Online background screening investigation for ....

Rectum

... colorectal cancer, also called colon cancer or large bowel cancer, includes cancerous growths in the colon, rectum and appendix. With 655,000 deaths worldw...

Post-meiotic segregation

...t rely on a post - meiotic mechanism. ... PMS2 ( post meiotic segregation increased 2) is a DNA mismatch repair protein ... nonpolyposis colorectal cancer type 4, PMSL2, postmeiotic segregation like 2. ... Sperm meiotic segregation studies performed in ... Meiotic segregation ... ab...
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(Date:4/23/2014)... Oncotarget , explored tumour heterogeneity where ... DNA signatures within the same cancer. Such differences ... treatment strategies. , Firstly they confirmed the mutual ... KRAS or BRAF mutation. Secondly, they found that ... have that specific mutation present uniformly throughout the ...
(Date:4/23/2014)... of endogenous neural precursor cells cannot alone compensate ... the perspective of neural plasticity, Dr. Yun Xiang ... observed the effects of functional electrical stimulation treatment ... of basic fibroblast growth factor and epidermal growth ... side. The researchers found that functional electrical stimulation ...
(Date:4/22/2014)... the United States with 1 million participants annually. A ... Injury Research and Policy at Nationwide Children,s Hospital is ... distribution patterns of basketball-related injuries treated in emergency departments ... and teens. , The study, published online in the ... to adolescents 13-19 years of age who were treated ...
(Date:4/22/2014)... recently FDA-approved device has been shown to reduce seizures ... 50 percent. When coupled with an innovative electrode placement ... facilitated the complete elimination of seizures in nearly half ... clinical trials. , That,s good news for a large ... living with epilepsy whose seizures can,t be controlled with ...
(Date:4/22/2014)... that can provide primary care for low-income patients ... and insurance companies while improving patient health, researchers ... suggests that health clinics that avoid costs associated ... by lowering hospital admission rates and emergency room ... Penn State Altoona. , The researchers estimated ...
Breaking Medicine News(10 mins):Health News:Non-uniform genetic mutations identified in lung cancers could lead to targeted treatment 2Health News:New study finds 2.5 million basketball injuries to high school athletes in 6 seasons 2Health News:New study finds 2.5 million basketball injuries to high school athletes in 6 seasons 3Health News:Newly approved brain stimulator offers hope for individuals with uncontrolled epilepsy 2Health News:Clinics not bogged down by red tape can ease health cost burdens 2
(Date:4/22/2014)... Consortium Ltd.,s nanotechnology expert will present a poster ... at the 7th International Nanotoxicology Congress to ... , Dr. Monita Sharma will outline a strategy consistent ... of Sciences, " Toxicity Testing in the 21st Century: ... of non-animal methods involving human cells and cell lines ...
(Date:4/22/2014)... for Experimental Biology (FASEB) has released updated factsheets ... from the National Institutes of Health (NIH) benefits each ... is pleased to make these factsheets available to help ... their state," said FASEB President, Margaret K. Offermann, MD, ... research funding, investing $29.2 billion in FY 2013 ...
(Date:4/22/2014)... of breeding bird surveys sent in by citizen scientists ... years, wildlife researchers report that most of the 40 ... higher elevation in response to climate change, but did ... previous studies of potential climate change impacts on wildlife ... have likely underestimated the effects of environmental warming, say ...
Breaking Biology News(10 mins):Wildlife response to climate change is likely underestimated, experts warn 2
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