Change in gene may be underlying molecular defect in some colorectal cancers
Inactivation of a DNA repair gene may be an early step in the development of sporadic
colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for
colorectal cancer, according to a new study in the September 21 issue of the Cancers can arise from a region of cells with a "field...
Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers
Cancer researchers are working toward a future in which each patient's tumor will act like a crystal ball, revealing how oncologists should treat the cancer to obtain the best outcome. Currently, physicians cannot predict which patients with prostate cancer should receive extra therapy after surgery - or whether some of these patients have an indolent disease that does not even require su...
Scientists identify a gene that may suppress colorectal cancer
In today’s online edition of , a husband-and-wife research team from Thomas Jefferson University report the discovery of a gene that, when mutated, may suppress
colorectal cancer. To conduct the study, the researchers used a strain of mice that develop polyps, or small growths of tissue, in the digestive tract—the harbingers of cancer. When these mice possessed one copy of...
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Detecting Colorectal Cancer
An innovative test to detect
colorectal cancer may be certain and more comfortable than current methods. Researchers in Boston, have developed a new technique that identifies a specific protein in a patient's stool that is only present in cancerous
colorectal cells. Researchers say the screening method may prove more reliable// than the standard tests, colonoscopy and fecal-blood assessment, in d...
Colorectal Cancer Can Be Detected By a Simple Test
The immunochemical faecal occult blood test (FOBT) is a simpler way of identifying individuals who might have
colorectal cancer, researchers claim in an article published online in The Lancet Oncology.// Conventionally, guaiac FOBT is used to screen individuals who might be having this cancer, but this new test "could decrease substantially the number of false positives in a screening programme f...
Early detection of colorectal cancer may be hindered by coloured toilet disinfectants
A new study published in the British Medical Journal has argued that the cause of failure in detecting
colorectal cancers at an early stage could be attributed to coloured toilet disinfectants. Researchers claimed that nine out of ten bowel and colon cancers detected early can be successfully treated and that once the cancer has spread cure rates drop dramatically. The National programme// for de...
Preventing Colorectal Cancer
New research shows taking vitamin D and consuming a diet high in fiber may reduce the risk of polyps, or tumors, that can lead to colon cancer.// Researchers from 13 Veterans Affairs medical centers studied more than 3,100 patients between ages 50 and 75. Results of their study show men who consume more than four grams of cereal fiber per day and more than 645 international units of v...
Screening Test For Early Diagnosis Of Colorectal Cancer
Colorectal cancer is the second leading cause of cancer death in the United States, partly because it is often detected at advanced stages. // Screening reduces death by detecting cancers earlier when they are more curable. A new study shows primary care providers do not screen all eligible patients for
colorectal cancer. Researchers attribute the limited use of these tests to four fact...
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Pocket Guide to Colorectal Cancer Drugs and Treatment
Description:Focuses primarily on the drugs used for treatment and symptom management for
colorectal cancer....
Company:Skyscape, Inc.
Microsatellite Instability (MSI) for Hereditary Nonpolyposis Colorectal Cancer
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories
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Merck at ASCO 2007: Spectrum of Studies Reinforces Promise of
Erbitux for Colorectal and Head and Neck Cancer Patients
CHICAGO, DARMSTADT, Germany, June 5, 2007 – Thisyear’s American Society of Clinical Oncology (ASCO) meetingin Chicago sees a wealth of promising new data presented regardingMerck KGaA’s targeted cancer therapy Erbitux®(cetuximab), further demonstrating the consistent efficacy andversatility of this agent in both first-line and subsequenttreatment of metastatic color...
Merck at ASCO 2007: New Data Demonstrate the Value of UFT as an
Important Treatment Option for Patients With Metastatic Colorectal
Cancer
CHICAGO/DARMSTADT, Germany, June 4, 2007 – Data presentedtoday at this year’s American Society of Clinical Oncology(ASCO) meeting in Chicago show that a novel combination regimenbased on Merck KGaA’s oral 5-fluorouracil (5-FU) therapy UFT(tegafur–uracil) plus leucovorin (LV) has shown an excellentresponse rate in the first-line treatment of metastatic
colorectalca...
Repeated Radioimmunotherapy With 131I-Labetuzumab Appears Safe and
Effective in Colorectal Cancer with Liver Metastases
- Initial Phase II Study Results Presented at Society of NuclearMedicine Annual Meeting - WASHINGTON, June 04, 2007 /PRNewswire-FirstCall/ --Immunomedics, Inc. , a biopharmaceutical company focused ondeveloping monoclonal antibodies to treat cancer and other seriousdiseases, today announced that its anti-carcinoembryonic antigen(CEA) antibody, labetuzumab, labeled with the radioisotope,i...
Eloxatin (oxaliplatin injection)-Based Chemotherapy Sets New
Treatment Benchmark in Patients With Metastatic Colorectal Cancer
FOLFOX4 Chemotherapy Results in Improved Long-term [Five-years]Overall Survival for these Seriously Ill Patients CHICAGO, June 04, 2007 /PRNewswire-FirstCall/ -- FOLFOX4, anEloxatin(R)-based chemotherapy regimen, provided significantimprovements in long-term [five- years] overall survival (OS) andtime to disease progression (TTP) - a longer period of stabledisease - in patients with metas...
The Eloxatin-Based Regimen (FOLFOX4) Significantly Improved
Progression Free Survival When Given Before and After Surgery in
Patients With Resectable Liver Metastases From Colorectal Cancer
Presentation at ASCO Plenary Session Reports EORTC 40983 (EPOC)Intergroup Study Results CHICAGO, June 04, 2007 /PRNewswire-FirstCall/ -- Results of therandomized phase III EORTC 40983 Intergroup study, or EPOC study,demonstrate for the first time that peri-operative (pre and postsurgery) FOLFOX4 (Eloxatin(R) (oxaliplatin injection) incombination with a standard chemotherapy regimen for co...
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Colorectal at Medicine Dictionary
Colorectal polyps
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Colorectal Cancer
become abnormal and divide without normal control or order, forming a mass...