Cytoplasm affects the number of vertebrae in carp-goldfish clones
The March 2005 issue of Biology of Reproduction contains a report of some intriguing findings in cloned offspring created when nuclei from one genus of fish were transplanted to enucleated eggs of another genus of fish. The seven offspring, cloned from nuclei of common carp and egg cytoplasm of goldfish, were virtually identical to the nuclear donor species, Cyprinus carpio, in appearance...Cloned stem cells prove identical to fertilized stem cells
Scientists generally agree that all cloned animals are biologically flawed. But they don't agree about what that means for stem cells derived from cloned embryos, the basis for therapeutic cloning. Also known as somatic cell nuclear transfer, therapeutic cloning is a promising approach to create individually customized cellular therapies for treating certain disorders. Demonstrated in mic...Cloned mice created from fully differentiated cells, a milestone in cloning research
New research dismisses the notion that adult stem cells are necessary for successful animal cloning, proving instead that cells that have completely evolved to a specific type not only can be used for cloning purposes, but they may be a better and more efficient starting point. As proof, researchers report they created two mouse pups from a type of blood cell that itself is incapable of dividing...Scientists clone mice from adult skin stem cells
For cells that hold so much promise, stem cells' potential has so far gone largely untapped. But new research from Rockefeller University and Howard Hughes Medical Institute scientists now shows that adult stem cells taken from skin can be used to clone mice using a procedure called nuclear transfer. The findings are reported in the Feb. 12 online edition of the Proceedings of the National Academ...Mouse Anti-Amodiaquine Monoclonal Antibody, Unconjugated, Clone 6D10 from AntibodyShop A/S
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Description:The JNK (c-Jun NH2-terminal kinase) signal transduction cascade is one of three identified MAP kinase pathways in mammals. JNK pathway activation occurs in response to environmental stress, is associated with the nuclear accumulation of JNK itself, and is implicated in the immune response, cellular proliferation, oncogenic transformation, morphogenesis, and apoptosis.JIP1 (JNK-interacting protein...Low Abundance cDNA Cloned Using Stratagenes Human Universal cDNA Library
Department of Cell Biology, Clevela...High-Throughput Cultivation of Bacterial Clones
Stratagene The tempest thermoshaker and a 96-deep-well round-bottom plate were used to cultivate bacterial clones in a...Sciclone ALH Bulk Dispense Precision Testing
Caliper Life Sciences Inc., Applications Laboratory, Hopkinton, Massachusetts, USA The ability to continuously dispense reagents across multi-well plates and into individual columns (secondary dispensing) is of great importance to high throughput laboratories. Equally important,...96 Well Pipetting Precision Testing Using the Sciclone ALH with a 384 Fixed-Cannula Array
The purpose of this...Endangered species may be successfully cloned in another animal's womb
Scientists for the first time have found a way for the survival of endangered animal species of the world. In a major breakthrough a Massachusetts scientists who engineered the feat has managed to clone cells from an endangered animal (Asian Gaur) and successfully impregnated an Iowa cow with the clone. The scientific journal Cloning has reported in its upcoming edition that...Organs made from cloned embryos
Using building material from cloned cow embryos, scientists say they have constructed miniature kidneys that appear to function similar to genuine organs. Embryos contain master cells called stem cells that have the potential to grow into any tissue in the body.// In this case, they grew the embryos to the stage where they could identify cells destined to become kidney cells. While it is still un...Rat joins list of cloned animals
Cloning will aid in the development of genetically modified rat models of greater predictability and quality. Scientific results obtained from these models will contribute to the development of innovative therapeutics for major pathologies such as cardiovascular diseases, //cancers, obesity, diabetes and neurological disorders. Rats and mice used in labs are inbred or genetically...Phase I Results for ImClone Pipeline Anti-IGF-1R Monoclonal Antibody IMC-A12 Presented at ASCO
NEW YORK--(BUSINESS WIRE)--Jun 5, 2007 - First-in-human results forIMC-A12, a monoclonal antibody developed by ImClone SystemsIncorporated (NASDAQ: IMCL) and targeted to IGF-1R (insulin-likegrowth factor type 1 receptor), were presented at the annualmeeting of the American Society of Clinical Oncology in Chicago.The IGF-IR is expressed on the cell surface of must human cancersand transmits...SciClone and Sigma-Tau Report Thymalfasin Meets Primary Endpoint in Phase 2 Malignant Melanoma Trial
-- Data Presented at Annual Meeting of the American Society ofClinical Oncology -- SAN MATEO, Calif. -- June 4, 2007 -- SciClone Pharmaceuticals,Inc. (Nasdaq:SCLN) and Sigma-Tau S.p.A today announced thatSciClone's lead product candidate thymalfasin (ZADAXIN(r), thymosinalpha 1) achieved its primary endpoint in a phase 2 clinical trialtreating patients diagnosed with stage IV malig...SciClone Announces ZADAXIN and SCV-07 Abstracts Accepted at ASCO
SAN MATEO, CA — April 27, 2007 — SciClonePharmaceuticals, Inc. (NASDAQ: SCLN) today announced that thefollowing abstracts have been accepted for the Annual Meeting ofthe American Society of Clinical Oncology in Chicago, Illinois onJune 1-5, 2007: ZADAXIN® (thymalfasin, thymosin alpha 1) PosterPresentation A large first-line, randomized, dose-finding, ph...ImClone Systems Showcases Extensive Research and Development Program at the AACR Annual Meeting
NEW YORK--(BUSINESS WIRE)--Apr 19, 2007 - IgG1 monoclonalantibodies developed by ImClone Systems Incorporated (NASDAQ: IMCL)were the focus of 44 total presentations at the recently concluded98th Annual Meeting of the American Association for Cancer Research(AACR), including seven oral presentations and 37 posters. Important ERBITUX(R) (cetuximab) clinical data were the focus oftwo back-to...