Genetic pathway responsible for link between body clock disturbance and worsening arthritis
Copenhagen, Denmark, Wednesday 10 June 2009: The genes that regulate human circadian rhythm, or 'the body clock', are significantly disturbed in individuals with arthritis, according to the results of a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rhe...Internal Clock and Metabolism May Be Linked
Discovery in mice could offer clues to effects of aging, experts say THURSDAY, March 19 (HealthDay News) -- A compound that plays an important role in coordinating people's circadian clocks and metabolism has been identified by U.S. researchers. The circadian clock governs daily c...UNC study supports role of circadian clock in response to chemotherapy
CHAPEL HILL For years, research has hinted that the time of day that cancer patients receive chemotherapy can impact their chances of survival. But the lack of a clear scientific explanation for this finding has kept clinicians from considering timing as a factor in treatment. Now, a new stud...Body clock linked to diabetes and high blood sugar in new study
Diabetes and high levels of blood sugar may be linked to abnormalities in a person's body clock and sleep patterns, according to a genome-wide association study published today in the journal Nature Genetics . The research suggests that diabetes and higher than normal blood sugar levels could...Turning back the Clock in Inherited Anemias
Reawakening a dormant gene could ease sickle-cell disease and thalassemia (Vocus) December 4, 2008 -- Researchers at Children's Hospital Boston ( www.childrenshospital.org ) and Dana-Farber Cancer Institute have identified a way to get red blood cells to produce a form ...Cephalon Announces Positive Results from a Phase Three Study of NUVIGIL in Jet Lag Disorder
...time. Circadian rhythm sleep disorders are disruptions in a person's internal body clock, which controls sleep patterns. When the internal body clock is disrupted, certain symptoms may develop affecting a person's ability to sleep, stay awake and function normally. Circadian rhythm sleep disorders c...IDM Pharma Announces Updated Data From Mifamurtide (L-MTP-PE) Compassionate Access Program
... a possible clinical benefit in terms of survival and granted the Company a clock stop, or time extension. The clock stop allows the Company additional time to respond to all the remaining que...IDM Pharma Announces Availability of Mifamurtide (L-MTP-PE) Through Compassionate Access Study
... a possible clinical benefit in terms of survival and granted the Company a clock stop, or time extension. The clock stop will allow the Company additional time to respond to all the remaining...Missing piece of plant clock found
Biologists at the University of California, San Diego have identified a key protein that links the morning and evening components of the daily biological clock of plants. Their discovery, detailed in the March 13 issue of Science , solves a longstanding puzzle about the underlying biochemical ...UNC study: Tinkering with the circadian clock can suppress cancer growth
CHAPEL HILL Researchers at the University of North Carolina at Chapel Hill have shown that disruption of the circadian clock the internal time-keeping mechanism that keeps the body running on a 24-hour cycle can slow the progression of cancer. The study disputes some of the most recent rese...How your body clock avoids hitting the snooze button
Scientists from Queen Mary, University of London have discovered a new part of the mechanism which allows our bodyclocks to reset themselves on a molecular level. Circadian clocks regulate the daily fluctuations of many physiological and behavioural aspects in life, and are synchronised with o...Circadian clock may be critical for remembering what you learn, Stanford researchers say
The circadian rhythm that quietly pulses inside us all, guiding our daily cycle from sleep to wakefulness and back to sleep again, may be doing much more than just that simple metronomic task, according to Stanford researchers. Working with Siberian hamsters, biologist Norman Ruby has shown tha...A mammalian clock protein responds directly to light
We all know that light effects the growth and development of plants, but what effect does light have on humans and animals? A new paper by Nathalie Hoang et al., published in PLoS Biology this week, explores this question by examining cryptochromes in flies, mice, and humans. In plants, cryptoch...Turning back the clock for Schwann cells
Myelin-making Schwann cells have an ability every aging Hollywood star would envy: they can become young again. According to a study appearing in the May 19 issue of the Journal of Cell Biology , David B. Parkinson (University College London, London, UK) and collogues have pinned down a protein t...deCODE Study Shows Complex Interplay of the Human Biological Clock With Height, Weight and Disease
Reykjavik, ICELAND, May 17 /PRNewswire-FirstCall/ -- In a paper published today in the online edition of Nature Genetics, scientists from deCODE genetics (Nasdaq: DCGN ) and academic colleagues from Iceland, Denmark and the Netherlands present the discovery of single letter variations in the ...Genetic clock makers at UC San Diego publish their 'timepiece' in Nature
UC San Diego bioengineers have created the first stable, fast and programmable genetic clock that reliably keeps time by the blinking of fluorescent proteins inside E. coli cells. The clock's blink rate changes when the temperature, energy source or other environmental conditions change, a fact ...Bacteria pack their own demise
... Brussel (VUB) were able to determine the structure and operating mechanism of the proteins involved. This clears the road for finding ways to set the clock on this internal time bomb and, hopefully, in the process developing a new class of antibiotics. The research was accepted for publication by top jo...Video shows nanotube spins as it grows
...by-frame analysis of the video showed that the rotation proceeded in discrete steps -- much like the halting motion of the second hand on a mechanical clock -- with about 24 steps per rotation. "The results support our predictions of how nanotubes grow," Yakobson said. "The video shows rotational moveme...Time Clocks Technology Catches Up With Crooks
...uck in traffic? Clocking on with a mechanical time clock where you grab your clock card from the rack and punch or time stamp it made...e no employees can give their finger to a buddy to clock on for them, fingerprint time clocks mean no more ...Neutral theory of molecular evolution
...s all species. Thus, the neutral theory is the foundation of the molecular clock technique, which evolutionary molecular biologists use to measure how muc...ion rate is no longer considered a constant, diverse and more sophisticated clock techniques have emerged. Many molecular biologists and population ge...