An entropy-based gene selection method for cancer classification using microarray data
Accurate diagnosis of cancer subtypes remains a challenging problem. Building classifiers based on gene expression data is a promising approach; yet the selection of non-redundant but relevant genes is difficult. The selected gene set should be small enough to allow diagnosis even in regular clinical laboratories and ideally identify genes involved in cancer-specific regulatory pathways. Here an...PANTHER Protein Classification System Database 5.0
PANTHER, a protein classification system fromApplied Biosystems, got updated to version 5.0. Proteins are classifiedby family, molecular and biological function (GO ontology) and knownpathways. Its main use is probably microarray analysis - it incorporateautomated GO surrepresentation analysis with graphical output. Best ofall, its available f...Towards precise classification of cancers based on robust gene functional expression profiles
Chemists say they have identified a gene that appears to play a key role in the development of type 1 diabetes, also known as insulin-dependent or juvenile diabetes, a disease that affects about one million people in the U.S. and is on the rise worldwide. They described their findings, which they say could lead to new drug interventions and possibly gene therapy, today at the 229th national meeti...Lipids get new comprehensive classification system
In response to the growing number of lipids expected to be discovered through lipidomics and in anticipation of the massive amounts of data that will be generated by the lipid community, an international group of scientists has developed a comprehensive classification, nomenclature, and chemical representation system for lipids. The details of the system appear in the May issue of the Journal of...New book expands biological classifications to account for 'alien' life
What would you call an alien if you encountered it on the street tomorrow? What if that alien didn't come from another world but rather was created in a laboratory right here on Earth and functioned differently from other Earth life? Either way, Peter Ward has the beginnings of an answer. In a new book, the University of Washington paleontologist puts forth an expanded "tree of life," or b...RNase Activity in Mouse Tissue: Classification, Hierarchy, and Methods for Control
RNase activity varies dramatically across different tissues. A comparison of total RNase activities for 8 different mouse tissues showed that total RNase activity spans a 181,000-fold range from pancreas to brain (Figure 1), which highlights the level of RNase control required for succ...Latest Tumor Classification More Informative
Clinicians say information about the genetic make-up of tumors help them decide on the most effective course of treatment for patients with cancer. To be most helpful these molecular data must be incorporated into a tumor classification // that includes morphological and clinical information. Specialists say, "The latest classification is simple (reducing the complexity of information r...Campaigners Say No To Cannabis Reclassification
There will be confusion if cannabis were to be reclassified again, according to campaigners. The UK’s Advisory Council on the Misuse of Drugs has reported that the drug //is connected to mental disorders. This may result in a reclassification of the drug again in less than three years. It had been classified as a Class C substance in the year 2003. An education campaign with regard to the...ICD-9-CM International Classification of Diseases, Ninth Revision, Clinical Modification
Description:The ICD-9-CM contains the numerical list of disease and code numbers in a format for your Palm or Pocket PC PDA or Smartphone. The International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) is based on the World Health Organization's Ninth Revision, International Classification of Diseases (ICD-9). ICD-9-CM is the official system of assigning codes to diagnoses and...FDA Re-Inspection Results in Positive Re-Classification of Guayama Facility
MADISON, N.J., May 9 /PRNewswire-FirstCall/ -- Wyeth (NYSE: WYE)today announced that the U.S. Food and Drug Administration's (FDA)San Juan District Office has informed the Company that the recentFDA re-inspection of its Guayama, Puerto Rico manufacturingfacility has resulted in a positive re- classification of the site.The new classification means that any issues found by the FDA haveeit...