New, automated tool successfully classifies and relates proteins in unprecedented way
For the first time, researchers haveautomatically grouped fluorescently tagged proteins fromhigh-resolution images of cells. This technical feat opens a new way toidentify disease proteins and drug targets by helping to show whichproteins cluster together inside a cell.The approach, developed by Carnegie Mellon University, outperformsexisting visual methods to localize proteins inside cells...Newly-discovered class of genes determines ?and restricts ?stem cell fate
Research on adult stem cells found in the skin hints at a new class of genes, according to a study from investigators at the University of Pennsylvania School of Medicine. These genes ?dubbed pangenes ?can both govern a stem cell's fate and put a hold on future differentiation until the time is right. Understanding the molecular control of these genes has implications for therapies that involve t...An entropy-based gene selection method for cancer classification using microarray data
Accurate diagnosis of cancer subtypes remains a challenging problem. Building classifiers based on gene expression data is a promising approach; yet the selection of non-redundant but relevant genes is difficult. The selected gene set should be small enough to allow diagnosis even in regular clinical laboratories and ideally identify genes involved in cancer-specific regulatory pathways. Here an...PANTHER Protein Classification System Database 5.0
PANTHER, a protein classification system fromApplied Biosystems, got updated to version 5.0. Proteins are classifiedby family, molecular and biological function (GO ontology) and knownpathways. Its main use is probably microarray analysis - it incorporateautomated GO surrepresentation analysis with graphical output. Best ofall, its available f...Towards precise classification of cancers based on robust gene functional expression profiles
Chemists say they have identified a gene that appears to play a key role in the development of type 1 diabetes, also known as insulin-dependent or juvenile diabetes, a disease that affects about one million people in the U.S. and is on the rise worldwide. They described their findings, which they say could lead to new drug interventions and possibly gene therapy, today at the 229th national meeti...Mouse Anti-Human HLA Class 1 A25 Monoclonal Antibody, Unconjugated, Clone 4i97 from Abcam
Description:Mouse monoclonal [4i97] to HLA Class 1 A25 ( P18462...MSC.12 class II safety cabinet (Type A1) - CE Marked (120V / 60Hz) from Thermo Scientific
Description:The Jouan MSC series of Class II Biological Safety Cabinets provides comfortable working conditions and certification to the world's highest safety standards. Fully automatic regulation ensures that the cabinets cannot be adjusted out of safe working conditions. Natural lighting, low noise and arm rest ensure safety through comfort....'Clickers' let professors quiz big classes instantly
Handheld devices that resemble TV remotes are catching on in large University of Wisconsin-Madison lecture halls, a professor says. But that doesn't mean students are kicking back and watching Comedy Central the 'clickers,' which usually have about a dozen buttons, let them respond instantly to multiple-choice questions posed by their professor. The anonymity is an encouragement to some...The Creative Class from my perspective
Rich Florida has taken a lot of crap from the academic community for the theory he vetted in his best-seller, The Rise of the Creative Class. To summarize, Dr. Florida says that a citys predisposition for Talent, Tolerance and Technology are indicators of economic boomtowns. Some of Richs indexes are controversial. For example, Rich shows that the higher a citys concentration of gays, t...RNase Activity in Mouse Tissue: Classification, Hierarchy, and Methods for Control
RNase activity varies dramatically across different tissues. A comparison of total RNase activities for 8 different mouse tissues showed that total RNase activity spans a 181,000-fold range from pancreas to brain (Figure 1), which highlights the level of RNase control required for succ...Screening and classifying hazardous waste samples
Timely and accurate analysis of hazardous materials is fundamental to environmental protection. In addition to the obvious necessity of identifying a suspected contaminant, a detailed analytical profile can help trace the source of a dangerous material and contribute to selecting the best containment and cleanup strategy. <P>A substantia...Latest Tumor Classification More Informative
Clinicians say information about the genetic make-up of tumors help them decide on the most effective course of treatment for patients with cancer. To be most helpful these molecular data must be incorporated into a tumor classification // that includes morphological and clinical information. Specialists say, "The latest classification is simple (reducing the complexity of information r...Ultrasound may mean end to classic stethoscope
Handheld ultrasound is the tool of choice for some doctors who think it's time to replace the stethoscope, which has seen little change since a French physician invented it in the early 1800s. "The stethoscope is based on sound, and the sound qualities //don't always allow you to distinguish between a heart that is beating well, and one that isn't," say some doctors. "Sometimes the hear...Self-Applied Acupressure May Reduce Sleepiness And Increase Alertness During Class Hours
Whether it's triggered by the monotone of an instructor or insufficient rest the night before, students at all ages and grade levels sometimes have trouble staying awake in class. Researchers have now found a way to combat the sleepiness // and to keep students awake during class, and it doesn't have anything to do with caffeine or high-sugar snacks. Students can increase alertness by...Madhya Pradesh Cops to attend Yoga classes to reduce stress and weight
Madhya Pradesh Police will have to reduce their weight and stress by undergoing Yoga following survey reports showing that most of the police personnel’s in a district in Madhya Pradesh were too much obese and had stress at work. // Highly feared bandit gang operate in parts of Madhya Pradesh mainly in the districts of Shivpuri which forms part of the Chambal ravines in northern and cen...Appendicitis: Evolving Tools to Diagnose a Classic Disease
Contributing Editor Appendicitis is a common, potentially lethal condition that affects 7% of individuals sometime in their lives. The condition occurs when the appendix, a blind pouch of intestine at the proximal colon, becomes obstructed by mucus, stool, or lymphatic tissue. Infection ensues, which can rapidly evol...Lpath Demonstrates 'First-in-Class' AMD Results With Its Lead Drug Candidate, Sphingomab
Sphingomab Shows Near-Complete Mitigation of ChoroidalNeovascularization (CNV) in an AMD Model SAN DIEGO, May 22, 2007 /PRNewswire-FirstCall/ -- Lpath, Inc. ,the category leader in therapeutic agents against bioactive lipids,reported compelling proof-of-concept data in a standard animalmodel of human age-related macular degeneration (AMD). The results were presented at the annual me...FDA Re-Inspection Results in Positive Re-Classification of Guayama Facility
MADISON, N.J., May 9 /PRNewswire-FirstCall/ -- Wyeth (NYSE: WYE)today announced that the U.S. Food and Drug Administration's (FDA)San Juan District Office has informed the Company that the recentFDA re-inspection of its Guayama, Puerto Rico manufacturingfacility has resulted in a positive re- classification of the site.The new classification means that any issues found by the FDA haveeit...