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Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. is the system of defenses designed to protect the integrity of the genome. Studies have suggested that deficiency...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

A team led by Johns Hopkins scientists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability to recognize and respond to a milliondifferent proteins might have originated from a family of genes whoseonly apparent function is to jump around in genetic material. essentially cut...

MetaChip provides quick, efficient toxicity screening of potential drugs

A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the U...

Hydrogen and methane provide raw energy for life at 'Lost City'

The hydrothermal vents were miles from where anyone could have imagined. One massive seafloor vent was an unheard of 18 stories tall. And all were creamy white and gray, suggesting a very different composition than vent systems studied since the 1970s. Scientists who named the spot Lost City knew they were looking at something never seen before when the field was serendipitously discovere...

Agilent Technologies introduces high-capacity human protein removal system for proteomics research

The fossilized skeleton of a small crocodile relative excavated last year at Petrified Forest National Park in Arizona throws a wrench into theories of how and where the dinosaurs arose more than 210 million years ago at the end of the Triassic Period. The animal, one of many creatures from the Late Triassic known only from their teeth, was thought to be an ancestor of the plant-eating or...

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Total antioxidant capacity Colorimetric Assay Kit from Neogen Corporation

Description:It has been demonstrated that oxidative stress is involved in atherosclerosis, chronic inflammatory disease, and cancer. Oxidative stress is the condition in which an imbalance between oxidant stimuli and physiological antioxidants exist leading to the damage of a cell. The bodys physiological response to oxidative stress is through several antioxidant systems4 that include enzymes and varying si...
Company:Neogen Corporation

8 Channel Syringe Dispenser, 20 cc Capacity from Biosearch Technologies

Description:Request Info...
Company:Biosearch Technologies

In Vitro Toxicity Testing Protocols, Vol 43 from Promega

Description:S. O'Hare & C.K. Atterwill • In vitro toxicity techniques for regular lab use. Ex vivo techniques are also covered with the aim of reducing and refining the use of animals in the future....
Company:Promega

Cytotoxicity Fluorometric (green / red) Assay Kit, LIVE/DEAD® from Molecular Probes (Invitrogen)

Description:LIVE/DEAD® Cell-Mediated Cytotoxicity Kit *for animal cells* *2000 assays*...
Company:Molecular Probes (Invitrogen)

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Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice or Rats

Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice orRats Precise and cost-effective micronucleus analysis made easy with theicroFlow Micronucleus Analysis Kit Litron Laboratories, Rochester, NY Mark J. Dycaico<br...

Greater Amplification Specificity with New Hot Start PCR Enzyme

Taq DNA polymerase makes hot start simple and efficient Jonathan Eads Frances Bai Ronda Allen Holly Hogrefe <p align="...

Versatile Transfection Reagent Offers Low Toxicity and Consistent Performance

Stratagene transfection reagent offersimproved, consistent transfections for both adherent cells and cells growing insuspension. In this article, we summarize the results of several experimentsthat characterize the eff...

Low-Toxicity, Lipid-Mediated Transfection of Mammalian Cells

Stratagene Cloning Systems Clonetics Corporation, Walkersville, Maryland LipoTAXI transfection reagent is a novel liposome reagent that offerslow cellular toxicity and high transfection efficiencies for adhe...

Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer

transgenicrodent mutation assay Centre for Environmental Health, University of Victoria, Victoria, BC Canada transgenic rodent mutationassay,* which carries the E. coli lacI transgene in a retrievabl...

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Carrying capacity

size neithe...

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B Vitamin protects and lowers toxicity of Arthritis Drug

Rheumatoid arthritis is an autoimmune disease that most often affects women in their 30s and 40s, especially women.The illness causes the immune system to attack the joints, which can cause pain, inflammation and joint destruction. Methotrexate is the standard drug used to treat the condition, but one third of the patients discontinue treatment early due to toxicity.//...

Andhra Pradesh to set up 'Pharma City'

After establishing a ‘Cyber City’ in Hyderabad, Andhra Pradesh chief minister Chandrababu Naidu has set into motion a plan to set up a ‘Pharma City’ in the port town of Vishakhapatnam. By providing world-class infrastructure in the ‘Pharma City’, the state government hopes to attract global pharmaceutical companies to the city for outsourcing about 400 drugs in the post-patent regime by 2...

Attacking therapy with electricity

The holes in the cell membranes which is being punched by electrical pulses could give better delivery of drugs. The effectiveness of many potentially powerful treatments //including cancer therapy and gene therapy are limited by the difficulty of getting drug molecules in through cell membranes. Researchers in San Diego, California, have been developing a new way of delivering drugs cal...

Toxin injections support stroke associated spasticity

Researchers have found that injections of botulinum toxin eases hand spasticity among stroke survivors. Spasticity in the limbs is a common after effect of stroke, and it causes much disability,// because it interferes with activities like getting dressed and eating. Previous research has shown that botulinum toxin - a substance that relieves muscle tightness - may help with this problem....

Melanoma caused by low DNA repair capacity

Melanoma is the deadliest form of skin cancer and it has been shown through previous research studies that the risk is increased by exposure to sunlight, whose UV rays cause damage to DNA that triggers cancer. However, it has not been clear why some people are more prone than others to melanoma. Researchers have now found out through a study involving a group of 312 people with melanoma t...

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Centricity Cardiology- Image Management and Archive

Description:GE's complex Cath Lab solution enhances your productivity and workflow efficiency across your department, your facility and your entire enterprise....
Company:GE Healthcare

Bx Velocity Rx

Description:Rapid Exchange Stent Delivery System...
Company:Cordis Corporation

Bx Velocity Hepacoat

Description:Bx VELOCITY Coronary Stent with HEPACOAT...
Company:Cordis Corporation

Bx Velocity Rx with Hepacoat

Description:Rapid Exchange Stent Delivery System with Hepacoat...
Company:Cordis Corporation

Centricity® Physician Office - Practice Management (PM)

Description:Millbrook Practice Manager® is now known as Centricity® Physician Office - Practice Management (PM). Centricity Physician Office - PM is designed to fit your current processes, size, and structure, providing an easily adaptable solution as individual as your practice. Thousands of physician offices of every specialty and size - have switched from yesterday's Unix and DOS-based systems to...
Company:GE Healthcare

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City at Medicine Technology

Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone

Interim results in a randomized phase II/III clinical trialanticipated later this year SEATTLE, June 26, 2007 /PRNewswire-FirstCall/ -- CellTherapeutics, Inc. (CTI) announced the publication of preclinicalstudies, which demonstrate that treatment with pixantrone (BBR2778) resulted in minimal or no significant cardiotoxicity, whiledoxorubicin and mitoxantrone induced significant cardiac da...

GlaxoSmithKline’s Hib-MenCY-TT Combination Vaccine Meets Phase II Study Endpoints of Immunogenicity and Safety Compared to Licensed Vaccines

Investigational vaccine could offer protectionfor infants against type b andmeningococcal disease — GlaxoSmithKline (GSK) announced results from aPhase II vaccine clinical study presented this week at thePediatri...

Study Supports Cost-Effectiveness of Medtronic's Spasticity Treatment for Children with Cerebral Palsy

MINNEAPOLIS--(BUSINESS WIRE)--Apr 26, 2007 - A new study publishedin the current issue of the Journal of Child Neurology indicatesthat a treatment from Medtronic, Inc. (NYSE:MDT), for spasticity inchildren with cerebral palsy improves their quality of life and iscost-effective compared to other established cost-effectivetreatments. The findings of this Medtronic-sponsored study shouldexpand...

Intercell AG: Novel tuberculosis Vaccine Shows Promising Immunogenicity and Safety Profile

The Danish Statens Serum Institut (SSI) and Intercell from a phase I clinicaltrial with a tuberculosis (TB) subunit vaccine The vaccine is produced by SSI and contains Intercell’sadjuvant IC31™...

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Spasticity

CINDY IVANHOE, MD: injury</ a...

Digitalis toxicity

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