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Cirrhosis in Medical News

Are angiotensins involved in the hemodynamic changes of cirrhosis patients?

Liver cirrhosis has been recently studied in the light of the new view of the renin angiotensin system (RAS). While the angiotensin converting enzyme (ACE)-Ang 2-AT1 receptor arm contributes to liver tissue injury and fibrosis and the maintenance of basal vascular tonus in non-compensated cirrhosi...

Liver Cirrhosis May Also Harm Brain, Heart

Inflammation may be the common link, study shows TUESDAY, Feb. 17 (HealthDay News) -- Increased inflammation caused by cirrhosis of the liver might lead people with this disease to also develop neurological, cognitive and heart rhythm problems, a new study finds. Cirrhosis of the ...

Is sildenafil safe in cirrhosis patients?

Sildenafil is valuable in the treatment of erectile dysfunction and pulmonary hypertension in patients with end-stage liver disease through inhibition of the type-5 phosphodiesterase. The type-5 phosphodiesterase is also present in human mesenteric arteries. The effect of sildenafil on splanchnic ...

Cause of effectiveness discovered for a cirrhosis treatment useful in 40 percent of patients

This release is available in Spanish . Scientists of the Center for Applied Medical Research (CIMA) of the University of Navarra have discovered the molecular mechanism responsible for the effectiveness of an existing treatment for primary biliary cirrhosis, which combines two substances in...

Research Offers Promise for Cirrhosis Treatment

Protein stops liver scarring in mice, study finds THURSDAY, Dec. 27 (HealthDay News) -- New findings about the inner workings of cells may be bringing scientists one step closer to reversing the scarring of the liver known as cirrhosis. Currently, the best treatment for advanced ci...

Amsterdam Molecular Therapeutics Initiates Program for Late Stage Liver Cirrhosis and Reports Strong Progress in AMT-011 With Trial Fully Recruited and European and US Submission On Track for First Half of 2008

Conference Call & Webcast Today at 10:30 CET AMSTERDAM, November 27 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, today announced it has signed an agreement with Digna Biotech/CIMA for the development of A...

Noninvasive tests for cirrhosis may help to avoid liver biopsy

Philadelphia, PA, October 1, 2007 Newer ultrasound and magnetic resonance (MR) imaging tests yield encouraging initial results in diagnosing fibrosis (scarring) and cirrhosis of the liver, according to three studies in the October issue of the journal Clinical Gastroenterology and Hepatology. ...

New research may lead to earlier diagnosis and treatment of primary biliary cirrhosis in families

ROCHESTER, Minn. -- Mayo Clinic researchers have found that first-degree relatives (i.e., parents, siblings, children) of patients with primary biliary cirrhosis (PBC) are more likely to have the biomarker of the disease in their blood. Armed with this new information, physicians could screen and ...

Primary biliary cirrhosis more severe in African-American and Hispanic patients

Non-Caucasian patients seeking medical care for primary biliary cirrhosis have more severe liver disease compared to Caucasian patients, a new study has found. The reasons for this disparity are not clear, say the authors. These findings are in the September issue of Hepatology, a journal publishe...

Alcoholics With Cirrhosis Have More Brain Damage

Genes connected with higher functions are changed by continued abuse, study finds TUESDAY, Aug. 28 (HealthDay News) -- Alcoholics with cirrhosis (scarring and dysfunction) of the liver have more brain function impairment than other alcoholics, according to new research. Researchers examined g...
Cirrhosis in Medical Technology

New Research May Lead to Earlier Diagnosis and Treatment of Primary Biliary Cirrhosis in Families

Study shows one in five sisters of a primary biliary cirrhosis patient has the biomarker of the disease ROCHESTER, Minn., Sept. 10 /PRNewswire-USNewswire/ -- Mayo Clinic researchers have found that first-degree relatives (i.e., parents, siblings, children) of patients with primary biliary ci...

Mayo Researchers Help Discover Genetic Cause for Primary Biliary Cirrhosis

ROCHESTER, Minn., May 27 /PRNewswire-USNewswire/ -- Researchers have discovered a novel molecular path that predisposes patients to develop primary biliary cirrhosis , a disease that mainly affects women and slowly destroys their livers. Primary biliary cirrhosis has no known cause. The fi...

ALP Life Sciences, LLC Announces Nanoveson(TM) Patent Filing and Whitepaper Availability on Proposed Therapy for Non-Alcoholic Fatty Liver Disease (NAFLD) and Comorbid Diseases

...nd other life threatening diseases. NAFLD is known to progress to more advanced liver diseases such as non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis and liver cancer. Nanoveson(TM) is a novel approach to treating and diagnosing liver diseases and comorbid diseases utilizing the principles of ...

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

...Ribavirin (IR) Therapy: Final Results of the EPIC3 cirrhosis Maintenance Trial(1) The large EPIC3 clinical...lion people worldwide. It is the leading cause of cirrhosis and liver cancer, and the number one reason for li...Ribavirin (IR) Therapy: Final Results of the EPIC3 cirrhosis Maintenance Trial. Oral presentation at: 44th Eur...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

...ensated liver disease and histological evidence of cirrhosis (Child-Pugh class A) and patients with HIV disease...ensated liver disease and histological evidence of cirrhosis (Child-Pugh class A). Alpha interferons, in...4. Chronic hepatitis C (CHC) patients with cirrhosis may be at risk of hepatic decompensation and death...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...ensated liver disease and histological evidence of cirrhosis (Child-Pugh class A) and patients with HIV disease...ensated liver disease and histological evidence of cirrhosis (Child-Pugh class A). Alpha interferons, in...4. Chronic hepatitis C (CHC) patients with cirrhosis may be at risk of hepatic decompensation and death...

ANA598 Demonstrates Potent Antiviral Activity at all Dose Levels in Completed Phase Ib Study in Hepatitis C Patients

...ion of the liver, which can lead to fibrosis and cirrhosis, and may ultimately lead to liver failure and/or liver cancer if not successfully treated. cirrhosis of the liver resulting from chronic HCV infection is the leading indication for liver transplantation in the U.S. Due to the asymptomatic nature of H...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

...isease, affecting nearly 5 million people in the United States, 5 million in Europe and some 200 million people worldwide. It is the leading cause of cirrhosis and liver cancer, and the number one reason for liver transplants in the United States and Europe. About PEGINTRON PEGINTRON is indicated f...

MultiCell Technologies Signs Liver Stem Cell R&D Agreement To Develop Products for the Study of Liver Cancer

...ome parts of the world, with more than 1 million new cases diagnosed each year. The NCI also reports that hepatocellular carcinoma is associated with cirrhosis of the liver in 50% to 80% of patients. Primary liver cancer is rarely discovered early, and often does not respond to current treatment. For ex...

FDA Approves an Expanded Indication for Peginterferon-Based Combination Therapy for Patients With Chronic Hepatitis C

...ive trial in which 2,293 adult patients with moderate-to-severe fibrosis or cirrhosis who failed previous treatment with combination alpha interferon/ribavirin w...ly 5 million people in the United States alone. It is the leading cause of cirrhosis and liver cancer, and the number one reason for liver transplants in the Un...
Cirrhosis in Medical Definition

Pathology

... Femoral - Umbilical - Incisional - Diaphragmatic Liver Alcoholic liver disease - Cholestasis - Hepatitis - Liver failure - cirrhosis - NASH - PBC - Budd-Chiari - Hepatocellular carcinoma Accessory digestive Gallbladder / Biliary tree ( Gallstones , Cholecystitis ...
Cirrhosis in Medical Dictionary

Cirrhosis

Cirrhosis is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrous scar tissue as well as regenerative nodules, leading to progressive loss of liver function. Cirrhosis is most... Overview of liver cirrhosis including information ...

Primary Biliary Cirrhosis

Primary biliary cirrhosis is an autoimmune disease of the liver marked by the slow progressive destruction of the small bile ducts within the liver. When these ducts are damaged, bile builds up in the liver (cholestasis) and over time damages the tissue. This can lead... Primary ...

Stool

... A stool analysis is a series of tests done on a stool (feces) sample to help ... Poop Scoop: Stool Color, Shape, Frequency. Are You at Risk for cirrhosis of ... ...

Portacaval shunt

... vein that drains blood from the lower two-thirds of the body. The most common causes of liver disease resulting in portal hypertension are cirrhosis caused by alcohol... In medicine, a shunt is a hole or passage which moves, or allows movement of fluid from one part of the body to another....

Pbc

...ouse accounting to PBC , and have been very happy with... Let PBC manage your company's monthly accounting ... Learn more about Primary Biliary cirrhosis ( PBC ), including a description, scope of the problem, causes, symptoms, risk factors, diagnosis, natural progression ... Green Cleaning Overview...

Liver transplant

...you become an active liver transplant candidate, your name will be placed on ... Who needs a Liver Transplant ? ... Does Every Patient with cirrhosis Need a Liver Transplant ? ... How do Patients get Placed on a Waiting List for Liver Transplant ? ... Qualifying for a Live Donor Liver T...

Liver disorders

...Induced Liver Disease. Chronic Liver Disease / cirrhosis ... When diagnosing liver disease, the phys...Biliary Cirrhosis· Primary ... ... more about cirrhosis of the liver including causes, diagnosis, sympt...ive Disorders Health Center. Font Size. A. A. A. cirrhosis of the Liver ... ... Herbal Liver Disorde...

Liver Diseases

...s the catch-all term that is applied to any medical disorder ... Alcoholic liver disease usually occurs after years of excessive drinking. ... cirrhosis is the final phase of alcoholic liver disease . ... ...

Liver biopsy

...emoved with a special needle to ... A liver biopsy can give valuable information regarding staging, prognosis, and management. ... finding of cirrhosis on liver biopsy will determine the need for ... A liver biopsy is often necessary for people with liver disease, including hepatitis. ....

Liver

...Disease Management & Transplant Program ... Recognizing Fatty Liver : Its Symptoms, Causes and ... Women with chronic liver disease or cirrhosis exhibit a higher risk of fetal ... Treatment involves prompt delivery, whereupon the liver disease quickly reverses. ... Liver cancer —...
Cirrhosis in Biological News

Gene variation may elevate risk of liver tumor in patients with cirrhosis

A particular gene variation appears to significantly increase the risk that individuals with cirrhosis of the liver will go on to develop hepatocellular carcinoma (HCC), a liver tumor that is the third leading cause of cancer death. In the January 2 Journal of the American Medical Association, re...

Double the death rate from cirrhosis for 'blue collar' men

School of Population Health Professors Jake Najman and Gail Williams and Stockholm University's Professor Robin Room examined death rates among Australian men from liver cirrhosis between 1981 and 2002. Their results were published in the May 2007 edition of the prestigious journal, Drug and Alc...

The hepatitis healing power of blueberry leaves

...e Hepatitis C virus, opening up a new avenue for treating chronic HCV infections, which affect 200 million people worldwide and can eventually lead to cirrhosis and liver cancer. Among the areas of especially high Hepatitis C incidence is the Miyazaki prefecture of southern Japan, a trend that led Hiroaki ...

American Chemical Society's weekly PressPac -- May 27, 2009

... as a potential new treatment for liver fibrosis the disease that leads to cirrhosis scientists in Tennessee are reporting. Their study is scheduled for the June 1 issue of ACS' Molecular Pharmaceutics , a bi-monthly journal. cirrhosis is the 12th leading cause of death in the United States. Ram Mahato and ...

Ocera Therapeutics licenses novel treatment for acute hepatic encephalopathy from UCLB

...e treatment of AHE in patients with advanced liver cirrhosis and acute liver failure. The licensing agreeme... Clinical trials in patients with AHE due to cirrhosis and acute liver failure will be carried out at Uni...es. It is estimated that there are up to 1 million cirrhosis patients in the U.S. Acute liver failure is a life...

When acute hepatitis develops into chronic hepatitis

...isease becomes chronic, that is to say, the viruses remain in the liver. If left untreated, chronic hepatitis B can lead to a change in consciousness, cirrhosis and cancer of the liver. Until today scientists have not fully understood the role that the immune system plays in characterising an acute or chronic ...

Preventing a broken heart: Research aims to reduce scarring from heart attacks

... formation may interact. The protein may also be important in treating other diseases resulting in severe fibrosis, adds Greenspan, including liver cirrhosis and interstitial lung disease. ...

Apple or pear shape is not main culprit to heart woes -- it's liver fat

... senior investigator Samuel Klein, M.D., the Danforth Professor of Medicine and Nutritional Science. "That can lead to serious liver disorders such as cirrhosis in extreme cases, but more often it tends to have metabolic consequences." Klein, who heads the Division of Geriatrics and Nutritional Science and ...

Toxic bile damages the liver

... to the toxic components of the bile, resulting in cirrhosis of liver, a transformation of liver cells into con...ion. This could explain some of the cases of liver cirrhosis of unknown origin and open up a new approach for t...atology". Some of the known frequent causes of cirrhosis of the liver are liver inflammation due to a virus...

Resveratrol prevents fat accumulation in livers of 'alcoholic' mice

... rate at which fat within the liver is broken down. Chronic alcohol consumption causes fat to accumulate and can lead to liver diseases, including cirrhosis and fibrosis of the liver. It can also result in liver failure. The study points to resveratrol as a possible treatment for alcoholic fatty liver dise...
Cirrhosis in Biological Technology

Three Rivers Announces Positive Results from Phase 3 DIRECT Trial of Once-Daily INFERGEN(R) with Ribavirin in Hepatitis C Virus Treatment Failures

... drop) with previous treatment and low fibrosis scores F0-F3 had SVRs of 10.7% and 31.6% for the 9 mcg and 15 mcg arms Patients with cirrhosis were less likely to benefit from retreatment with INFERGEN and RBV unless they displayed previous interferon sensitivity of at least 1-log drop in vir...

Study Finds Noninvasive Blood Test for Liver Fibrosis May Alleviate Need for Liver Biopsies for Some Patients with Chronic Hepatitis C

...brosis without conducting a liver biopsy, a painful procedure that can miss cirrhosis in some patients," said Nezam H. Afdhal, M.D., study investigator and direc...most common cause of liver fibrosis, a condition that can progress to liver cirrhosis or cancer. Physicians manage HCV infection based on assessments of the degr...

Ocera Therapeutics Presents Data on AST-120 in Patients With Hepatic Encephalopathy at the European Association for the Study of Liver Disease Annual Meeting

...is, M.D., Ocera's chief medical officer, "Up to 60 percent of patients with cirrhosis have MHE and impaired neurocognitive function, a condition for which no dru...era is developing OCR-002 in hepatic encephalopathy due to complications of cirrhosis and acute liver failure. Ocera has raised $62.5 million dollars in venture...

Aethlon Medical Announces Data Supported Strategy to Increase Hepatitis-C (HCV) Cure Rates

...uals are chronic HCV carriers who are at increased risk of developing liver cirrhosis or liver cancer, approximately 15 million of whom are in the United States,...ients develop some form of chronic liver disease, including, in some cases, cirrhosis or liver cancer. In the United States, the current standard of care fo...

ANA598 Receives Fast Track Designation From the FDA for the Treatment of Chronic Hepatitis C Infection

...ion of the liver, which can lead to fibrosis and cirrhosis, and may ultimately lead to liver failure and/or liver cancer if not successfully treated. cirrhosis of the liver resulting from chronic HCV infection is the leading indication for liver transplantation in the U.S. Due to the asymptomatic nature of H...

Anadys Pharmaceuticals Commences Dosing ANA773 in Hepatitis C Patients

...tion of the liver, which can lead to fibrosis and cirrhosis, and may ultimately lead to liver failure and/or liver cancer if not successfully treated. cirrhosis of the liver resulting from chronic HCV infection is the leading indication for liver transplantation in the United States. Due to the asymptomatic na...

FDA Grants Full Approval of PROCLEIX(R) ULTRIO(R) Blood Screening Assay

...st common serious liver infection in the world and is transmitted through contact with blood and body fluids. HBV infection can lead to liver failure, cirrhosis or cancer. According to the World Health Organization, more than 350 million people worldwide are chronically infected with HBV. More than one million...

Arbios Announces It Has Suspended Operations

...body) liver assist device for blood purification of patients suffering from cirrhosis due to chronic liver disease and who are hospitalized with acute complicati...Hepatic encephalopathy represents one of the most frequent complications of cirrhosis necessitating hospitalization, and SEPET's rapid time to a sustained two-st...

Improved culture system for hepatitis C virus infection

... that, closer to 20 percent, in individuals with liver cirrhosis. It can also cause severe flu-like side effects. Approximately 10,000 deaths due to cirrhosis of the liver and several thousand more from liver cancer are attributed to HCV infection in the United States each year. The HCV life cycle is only...

Beckman Coulter Acquires Rights to Hepatitis C Virus

...n additional 3 to 4 million people are newly infected each year. A hepatitis C infection can cause acute hepatitis and chronic liver disease including cirrhosis and liver cancer. Two thirds of all liver transplants in developed countries are the result of these diseases(1). Scott Garrett, chairman, president...
Cirrhosis in Biological Definition

Albumin

...njugated bilirubin Transports many drugs Competitively binds calcium ions (Ca 2+ ) Buffers pH Causes of albumin deficiency: cirrhosis of the liver (most commonly) Decreased production (as in starvation) Excess excretion by the kidneys (as in nephrotic syndrome ) Excess l...

Hepatitis B

...ction with Hepatitis D increases the risk of liver cirrhosis and subsequently, liver cancer. Hepatitis B infe...o a chronic inflammation of the liver, leading to cirrhosis . This type of infection dramatically increases th...d consuming alcohol as it increases their risk for cirrhosis and hepatocellular carcinoma (liver cancer). Inf...

Liver

...the ligamentum venosum . In the disease state of cirrhosis and portal hypertension , the umbilical vein can...oisons, autoimmunity or hereditary conditions. cirrhosis is the formation of fibrous tissue in the liver, ...e duct , autoimmune in nature. Primary biliary cirrhosis , autoimmune disease of small bile ducts Budd-...
Cirrhosis in Biological Dictionary

Liver

...used by viruses ... The liver then becomes unable ... Learn more about cirrhosis of the liver including causes, diagnosis, symptoms, and treatment. ... Fa.... main types of liver biopsy are percutaneous, ... Overview of liver cirrhosis including information about the causes, symptoms,complications, and treatme...
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