Male Sex Chromosome on Its Way Out: Study
But researchers believe a replacement will take over
FRIDAY, July 17 (HealthDay News) -- Rapid evolution of the male sex chromosome
could result in its disappearance within a few million years. But that won't mean the end of males, say U.S. scientists.
Penn State researchers found t...
International Collaboration led by Dr. Pablo V. Gejman,Researcher At NorthShore University HealthSystem's Research Institute, Finds Genetic Association of Schizophrenia to Chromosome 6p Variant
The July 1, 2009 advance online edition of the journal Nature includes three companion papers describing the results of genome-wide association studies (GWAS) of schizophrenia. Schizophrenia is an elusive and severe psychiatric disorder that affects up to 70 million people worldwide. The causes o...
UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage
UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome
damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.
Researchers found that lo...
RevGenetics Releases Its New Science-Based Telomere Health Supplement Formulation for DNA and Chromosome Health
Astral Fruit, a new health supplements product, helps slow and repair some of the natural telomere DNA shortening that happens as we age
MIAMI, May 18 /PRNewswire/ -- RevGenetics announces the update and release of its latest science-based telomere health supplements , Astral Fruit. To...
Molecule tracking reveals mechanism of chromosome separation in dividing cells
University of Washington (UW) researchers are helping to write the operating manual for the nano-scale machine that separates chromosomes before cell division. The apparatus is called a spindle because it looks like a tiny wool-spinner with thin strands of microtubules or spindle fibers sticking o...
CSHL scientists discover link between control of chromosome duplication and segregation
Cold Spring Harbor, N.Y. Before a cell can divide into two, first it must duplicate its genetic material--the DNA packed in its chromosomes. The two new sets of chromosomes then have to be separated from one another and correctly distributed to the resulting "daughter" cells, so that both daughte...
Chromosome in Medical Technology
Quest Diagnostics Introduces ClariSure(TM) Test for Identifying Chromosome Abnormalities Associated With 85 Developmental Disorders in Children
First commercial test available nationally
LYNDHURST, N.J., Aug. 30 /PRNewswire-FirstCall/ -- A molecular
diagnostic test that detects chromosome
abnormalities associated with 85
developmental disorders affecting children now is commercially available
from a national diagnostic ...
deCODE Discovers Second Common Genetic Risk Factor for Atrial Fibrillation and Stroke
...ed monitoring for AF. The study is published online today in Nature
Genetics at http://www.nature.com/ng .
The new SNP is in the ZFHX3 gene on chromosome
16q22, and the more than
one third of people of European descent who carry one copy are at
approximately 20% greater risk of AF and cardioembolic stro...
deCODE-led Megastudy Finds New Genetic Clues to Causes of Schizophrenia
...schizophrenics. Another SNP is in the transcription factor 4
(TCF4) gene on chromosome
18, which is involved in brain development. Five of
the SNPs are located very closely together in the Major Histocompatibility
Complex, a region on chromosome
6 densely packed with genes regulating immune
response. This lends support ...
Gene Findings Unlocking Reasons for Neuroblastoma Risk
...ch of DNA -- along a structurally weak location on chromosome
1 plays an important role in the development of ne...iladelphia, found that an inherited CNV located at chromosome
1q21.1 is associated with neuroblastoma. The chromosome
region contains a large family of genes that are i...
Celladon Provides MYDICAR(R) Program Update of First-In-Human Trial for Advanced Heart Failure at American Society of Gene Therapy Annual Meeting
...er agents, and are derived from components of a non-replicating, non-pathogenic, commonly occurring human virus. AAV vectors do not integrate into the chromosome
and are considered non-mutagenic. In addition, they have not been associated with the types of inflammatory reactions observed in trials involving ade...
Autism Genes Discovered; Help Shape Connections Among Brain Cells
...e strongly influenced by genetics. Previous studies have implicated several chromosome
regions harboring rare variants in raising the risk of ASDs, but until now,...ikely than healthy controls to have gene variants on a particular region of chromosome
5. That region is located between two genes, cadherin 9 (CDH9 ) and cadher...
Chromosome in Medical Products
Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
MIS/AMH ELISA Test
Description:...regulation of tissue growth and differentiation. The human gene coding for MIS/AMH has been sequenced and isolated, and is located on the short arm of chromosome
19 (3). The structure of a specific receptor for MIS/AMH has also been isolated and characterized (4).
MIS/AMH is produced by the Sertoli cells of t...
Company:Diagnostic Systems Laboratories, Inc.
Baby Gender Mentor Home DNA Genter Test
Description:... from maternal DNA is if the baby is a boy and has a Y chromosome. If the Y chromosome
DNA is present in your maternal blood sample, it's a boy; if the Y chromosome
DNA is not present, you're having a girl....
Company:Acu-Gen Biolab, Inc.
HER2 FISH pharmDx Kit
Description:...en the number of signals from the hybridization of the HER2 gene probe (red signals) and the number of signals from the hybridization of the reference chromosome
17 probe (green signals)....
Company:DakoCytomation California Inc.
Vysis UroVysion Bladder Cancer Kit
Description:...9, and 17. The UroVysion probe mixture consists of chromosome
Enumeration Probe (CEP) CEP 3 SpectrumRed, CEP 7 S...nd visualized, these probes provide information on chromosome
copy number for chromosome
Description:...ives have been designed especially for qualitative and quantitative analyses of ion movements and for particularly critical fluorescence methods (e.g. chromosome
studies in human and cytogenetics)....
Company:Carl Zeiss MicroImaging, Inc.
Chromosome in Medical Definition
...y renal carcinoma
v • d • e
Pathology : chromosome
abnormalities ( Q90-Q99 )
Down syndrome (...nefelter's syndrome , XYY syndrome
, Burkitt's lymphoma
Sexual orientation and medicine
^ Hamer, Hu, Magnuson, Hu and Pattatucci (1993) A linkage between DNA markers on the X chromosome
and male sexual orientation. Science 261(5119): pp. 321-7.
^ Healthy People 2010, 2nd ed. "A Systematic Approach to Health Improvement" http://...
Chromosome in Medical Dictionary
Fact sheet on chromosome
microdissection, published by the National Human Genome Research Institute. ... Fact Sheets Chromosome
Microdissection Fact Sheet ... Each chromosome
has a distinct ... This method of mapping a gene to a particular band of the chromosome
is called cytogenetic ...
... by 20 ... Yawning is commonly ... Online Medical Dictionary and glossary with medical ... Yawn . Yawning . Yaws. yd. Yeast. Yeast artificial chromosome
(YAC) Yeast diaper rash. Yeast genome ... Why do we yawn ... A part of the brain that plays an important role in yawning is the hypothalamus....
...n Hippel - Lindau (VHL) disease, von Hippel - Lindau syndrome, is a rare ... The von Hippel - Lindau gene is located on the short arm of chromosome
3 (3p26-p25) ... Overview: von Hippel - Lindau disease (or von Hippel disease) exhibits the ... von Hippel - Lindau disease usual...
.... About the ... Velo - cardio - facial syndrome (VCFS) is a genetic condition that is related to DiGeorge syndrome and involves a similar chromosome
abnormality as DiGeorge syndrome . What is velo - cardio - facial syndrome (VCFS)? Velo - cardio - facial syndrome (VCFS) is a genetic ...
...essive manner. ... Article describes tyrosinemia type I, its symptoms, diagnosis, and treatment. ... Tyrosinemia is an inherited disorder of chromosome
15 which affects males and ... ...
...bout 30 percent of people with Turner syndrome have extra folds of skin on the ... Learn about Turner syndrome , an abnormality in the X chromosome
of females that ... Turner syndrome is a chromosomal condition that alters development in females. ... Offers an information resource for tho...
Chromosome in Biological News
Double success for Instituto Gulbenkian de Ciencia scientists working on chromosome segregation
Lars Jansen's work on the formation of the centromere, a key cellular structure in powering and controlling chromosome
segregation and accurate cell division, has just earned him a paper in Nature Cell Biology and a prestigious EMBO installation grant, of 50,000 euro per year, for a maximum of f...
Y chromosome and surname study challenges infidelity 'myth'
Our surnames and genetic information are often strongly connected, according to a study funded by the Wellcome Trust. The research, published this week in the journal Molecular Biology and Evolution , may help genealogists create more accurate family trees even when records are missing. It also s...
Mayo: Variants in gene on X chromosome associated with increased susceptibility to Alzheimer's
JACKSONVILLE, Fla. Researchers at Mayo Clinic have discovered the first gender-linked susceptibility gene for late-onset Alzheimer's disease.
In the Jan. 11 online edition of Nature Genetics , they report the results of their two-stage genome-wide association study of patients with Alzheimer...
How chromosomes meet in the dark -- Switch that turns on X chromosome matchmaking
A research group lead by scientists at the University of Warwick has discovered the trigger that pulls together X chromosomes in female cells at a crucial stage of embryo development. Their discovery could also provide new insights into how other similar chromosomes spontaneously recognize each ot...
Aberrations in region of chromosome 1q21.1 associated with broad range of disorders in children
Researchers have discovered a submicroscopic aberration in a particular region of human chromosome
1q21.1 that appears to be associated with a variety of developmental disorders in children. The aberration can manifest itself as unexplained mild or moderate mental retardation, growth retardation, ...
Y chromosome study sheds light on Athapaskan migration to southwest US
A large-scale genetic study of native North Americans offers new insights into the migration of a small group of Athapaskan natives from their subarctic home in northwest North America to the southwestern United States. The migration, which left no known archaeological trace, is believed to have o...
Chromosome in Biological Technology
New Initiative Has Shocking Effect: Thousands of Missourians with Abnormal Chromosome Structures Are Not Human
ST. LOUIS, Aug. 27 /PRNewswire-USNewswire/ -- Missouri Coalition for
Lifesaving Cures revealed today a consequence of the deceptive and far-
reaching initiative petition filed last week by opponents of embryonic stem
cell research: It is so poorly worded and scientifically unsound that it
It's Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer
...ure. One of these, in the keratin 5 (KRT5) gene on chromosome
12, leads to a subtle but potentially damaging alt...0% greater risk. Another of the SNPs is located on chromosome
9p21, the same region of the genome that deCODE ha...eland to demonstrate that a third risk variant, on chromosome
7q32, confers greater risk if inherited from the f...
deCODE Discovers a Gene Linked to Risk of Kidney Stones and Osteoporosis
...tones and decreased bone mineral
density (BMD). About 60% of the population carry two copies of a
single-letter variation in the human genome (SNP) on chromosome
them at roughly 65% greater likelihood of developing kidney stones than those
who carry no copies. This single variant may thus account fo...
Fallopian tubes offer new stem cell source
...l stem cells could be easily isolated and expanded in vitro, and are able to differentiate into muscle, fat, cartilage and bone cell lines. The cells' chromosome
complement showed no abnormalities, suggesting chromosomal stability. Jazedje comments, "In addition to providing an additional potential source for r...
Matrix Genomics, Elizabeth Corder, PhD - Gene Variation in the LRRK2 Gene and High Risk for Parkinson's Disease
...the general population. The signature is found in the LRRK2 gene located on chromosome
12. The work was led by Elizabeth Corder, PhD, Scientific director at Matri...the general population. The signature is found in the LRRK2 gene located on chromosome
12. The work was led by Elizabeth H. Corder , PhD, Scientific Director at ...
deCODE genetics Announces First Quarter 2009 Financial Results
...pe 2 diabetes (T2D). The markers include
SNPs discovered by deCODE on chromosome
9p21 linked to increased risk
of heart attack and types of aneurysm, on chromosome
risk of AF and stroke, and in the TCF7L2 gene linked ...
Chromosome in Biological Products
Chicken Anti-G4-1 (Hypothetical protein FLJ20644, likely ortholog of mouse phosphatase subunit gene g4-1) Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.
Description:...FLJ20644, likely ortholog of mouse phosphatase subunit gene g4-1 Protein Accession #: NP_060387.1 gi number query: 8923600 Genbank Definition: chromosome
14 open reading frame 10; likely ortholog of mouse phosphatase subunit gene g4-1 [Homo sapiens] Locus ID: 55012 calcium ion binding,...
Company:GenWay Biotech, Inc.
SPoT-Light EGFR Probe from Invitrogen
Description:... Intended to qualitatively detect EGFR gene amplification in formalin-fixed, paraffin-embedded (FFPE) tissue sections, metaphase chromosome
spreads, and cell preparations, using Chromogenic In Situ Hybridization (CISH). Fluorescent In Situ Hybridization (FISH) may also be used....
Rabbit Anti-Human ALS2CR2 Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.
Description:... amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 2...
Company:Proteintech Group, Inc.
* Quick & Easy E. coli Gene Deletion Kit from Gene Bridges GmbH
Description:... This kit is designed to knockout or alter genes on the E.coli chromosome
in less than one week. Red/ET recombination allows the exchange of genetic information in a base pair precise, specific, and faithful manner. An FRT-f...
Company:Gene Bridges GmbH
Mouse Anti-Human ALS2CR8 Polyclonal Antibody, Unconjugated from Novus Biologicals
Description:... Mouse polyclonal antibody to ALS2CR8 - amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 8...
BacMagic™ DNA Kit from Novagen
Description:...que purification. The BacMagic DNA is an AcNPV genome with a portion of the essential open reading frame (ORF) 1629 deleted and a bacterial artificial chromosome
(BAC) in place of the polyhedrin (polh) coding region. This combination prevents nonrecombinant virus from replicating in insect cells, yet allows the...
Chromosome in Biological Definition
For information about chromosomes in genetic algorithms , see Chromosome
(genetic algorithm) .
Figure 1: Chromosome. (1) Chromatid . One of the two identical parts of the chromosome
after S phase . (2) Centromere . The point where the two chromatids touch, and where the microtu...
The X chromosome
is one of the two sex chromosomes in humans and other animals (the other is the Y chromosome
). It is a part of the XY sex-determination system .
2 Role in disease
2.1 Numerical abnormalities
The Y chromosome
is one of the two sex chromosomes in humans (the other is the X chromosome
). The sex chromosomes are one of the 23 pairs of human chromosomes. The Y chromosome
spans about 50 million base pairs (the building material of DNA ) and represents between 1.5 and 2 percent of the ...
... An allele is any one of a number of alternative forms of the same gene occupying a given locus (position) on a chromosome
. An example is the gene for blossom color in many species of flower - a single gene controls the color of the petals, but there may be several diff...
...versity of a species population , or equivalently the richness of its gene pool . Allele frequency is defined as follows:
Given a) a particular chromosome
locus , b) a gene occupying that locus, c) a population of individuals carrying n loci in each of their somatic cells (e.g. two loci in the ce...
...contrast yeast and certain protozoa use anaphase B as the main means of chromosome
separation and can extend the spindle to up to 15 times its metaphase lengt... cytokinesis
Chromosome in Biological Dictionary
is an organized structure of DNA and protein that is found in cells. It is a single piece of coiled DNA containing many genes, regulatory elements and other nucleotide sequences. Chromosomes also contain... chromosome
( ) n. A threadlike linear strand of DNA and associat...
The Y chromosome
is the sex-determining chromosome
in most mammals, including humans. In mammals, it contains the gene SRY, which triggers testis development, thus determining sex. The human Y chromosome
is composed of about... The Y chromosome
spans about 58 million base pai...
The X chromosome
was named for its unique properties by early researchers, and ... The X chromosome
carries a couple thousand genes but few, if any, of these have ... The X chromosome
spans about 155 million base pairs (the building blocks of DNA) ... Genes on the X chromosome
A sex -determination system is a biological system that determines the development of sexual characteristics in an organism. Most sexual organisms have two sexes. In many cases, sex determination is genetic: males and females have different alleles or even different... The XY sex -dete...
Homologous chromosomes are chromosomes in a biological cell that pair (synapse) during meiosis. The pair are non-identical chromosomes that both contain information for the same biological features and contain the same genes at the same loci but possibly each have different alleles at t...
Cell division is a process by which a cell, called the parent cell, divides into two or more cells, called daughter cells. Cell division is usually a small segment of a larger cell cycle. This type of cell division in... ... centromere, becoming two individual daughter chromosom...