50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel
Researchers at the University of Chicago have found that a recently discovered biological process known as sumoylation -- until now thought to be active only in the nucleus -- also occurs near the cell's surface where it regulates at least one and possibly many kinds of proteins, providing a novel target for the development of new drugs. The discovery, published in the 8 April 2005 issue o...Some Brain Cells 'Change Channels' To Fine-tune The Message
Johns Hopkins researchers have identified the proteins that allow specific brain cells to "change channels," a rare ability that tweaks what can come into the cell. The findings, described in the March 24 issue of Neuron, may let researchers harness the process, perhaps one day using it to protect cells that die in Lou Gehrig's disease. Much as turning the television dial changes what come...Some Brain Cells Change Channels
Johns Hopkins researchers have identified the proteins that allow specific brain cells to "change channels," a rare ability that tweaks what can come into the cell. The findings, described in the March 24 issue of Neuron, might let researchers harness the process, perhaps one day using it to protect cells that die in Lou Gehrig's disease. Much as turning the television dial changes what co...Cells direct membrane traffic by channel width
For a glycerol molecule, a measly angstrom's difference in diameter is a road-closed sign: You can't squeeze through unless you are a sleek, water-molecule-sized sports car, say scientists at the University of Illinois at Urbana-Champaign. The roadway is in aquaporins, a class of proteins that form trans-membrane channels in cell walls in all forms of life. They allow for water movement be...Zooming in on the protein-conducting channel
Researchers have gained the most detailed view yet of the heart of the translocon, a channel through which newly constructed proteins are inserted into the cell membrane. The process of transporting proteins across or into membranes is a critical function that occurs in every cell. Howard Hughes Medical Institute investigator Joachim Frank at the Wadsworth Center and his colleagues reporte...Complete 2 channel polarographic oxygen monitoring system from Instech Solomon
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Description:0-10 psi precision pressure regulator and pressurized syringe holder for any researcher who needs: Connect to hou...Merge eFilm Builds Distribution Channel
MILWAUKEE, WI - - has signed agreements with four European companies to resell or distribute Merge eFilm's FUSION RIS/PACS and eFilm Workstation solutions. These full-service healthcare solution firms will increase the availability of Merge eFilm's products and services throughout European healthcare organisat...Multichannel Pipetting: How to Choose the Correct Pipettor
by Sari Mannonen, Pasi Nieminen, Jukka Kaasinen and Kati Andersin Multichannel pipettors are widely used in microplate work, includingserological testing, molecular biology, immunology assays, andpolymerase chain reaction (PCR). The explosion of specific markets suchas genome projects and drug discovery has further increased the use ofthe microplate. Because mic...Feeding channel created by malaria parasite - a new target for malaria treatments
Researchers have found pore-like holes in the membranes of red blood cells infected by the deadliest form of the malaria parasite. The parasite, Plasmodium falciparum, apparently uses these holes to supply itself with the nutrients it needs to grow and reproduce. The discovery may lead to the development of new treatments for malaria, a widespread and devastating disease. Mala...A Call To Open Up The Channel Of Goodwill To Rescue The Dying Hearts
The plight of poor children with congenital heart diseases (CHD) here moved NRIs into donating// $200,000 at a fund-raiser dinner held in the US by a non-profit organization. About 40-50 NRIs have offered to sponsor a child each. Some of them are keen to sponsor a child or two every year According to medical reports, every year, nearly 200,000 children are born in India with CHD. Only...New Way to Open Cellular Ion Channels, Implications for Drug Design
Using an enzyme found in the venom of the brown recluse spider, researchers at the University of Pennsylvania School of Medicine have discovered a new way to open// molecular pores, called ion channels, in the membrane of cells. The research team – Zhe Lu, MD, PhD; Yajamana Ramu, PhD; and Yanping Xu, MD, PhD of the Department of Physiology at Penn – screened venoms from over 100 pois...Altered Sodium Channel Function Linked to Heart Failure
The results of a study, using mice and heart muscle cells from rabbits, by researchers from Georg-August-University G?ttingen, Germany, have provided// a potential molecular explanation for the abnormally rapid heartbeats known as ventricular tachyarrhythmias (VTs) that can cause the sudden death associated with heart failure. Individuals who inherit mutations in genes regulating the...MEDPOR Miniplate Channel Implant
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ACTION-trial shows medical and economic advantages of nifedipineGITS therapy LEVERKUSEN, Germany, March 28, 2007 – Two recentlypublished articles in the Journal of Clinical Epidemiology providefurther evidence that the use of the long-acting calcium channelblocker (CCB) nifedipine GITS (Adalat? GITS) has additionalbenefits beyond its blood pressure lowing effec...