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50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

Researchers at the University of Chicago have found that a recently discovered biological process known as sumoylation -- until now thought to be active only in the nucleus -- also occurs near the cell's surface where it regulates at least one and possibly many kinds of proteins, providing a novel target for the development of new drugs. The discovery, published in the 8 April 2005 issue o...

Some Brain Cells 'Change Channels' To Fine-tune The Message

Johns Hopkins researchers have identified the proteins that allow specific brain cells to "change channels," a rare ability that tweaks what can come into the cell. The findings, described in the March 24 issue of Neuron, may let researchers harness the process, perhaps one day using it to protect cells that die in Lou Gehrig's disease. Much as turning the television dial changes what come...

Some Brain Cells Change Channels

Johns Hopkins researchers have identified the proteins that allow specific brain cells to "change channels," a rare ability that tweaks what can come into the cell. The findings, described in the March 24 issue of Neuron, might let researchers harness the process, perhaps one day using it to protect cells that die in Lou Gehrig's disease. Much as turning the television dial changes what co...

Cells direct membrane traffic by channel width

For a glycerol molecule, a measly angstrom's difference in diameter is a road-closed sign: You can't squeeze through unless you are a sleek, water-molecule-sized sports car, say scientists at the University of Illinois at Urbana-Champaign. The roadway is in aquaporins, a class of proteins that form trans-membrane channels in cell walls in all forms of life. They allow for water movement be...

Zooming in on the protein-conducting channel

Researchers have gained the most detailed view yet of the heart of the translocon, a channel through which newly constructed proteins are inserted into the cell membrane. The process of transporting proteins across or into membranes is a critical function that occurs in every cell. Howard Hughes Medical Institute investigator Joachim Frank at the Wadsworth Center and his colleagues reporte...

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Channel at Biology Products

Complete 2 channel polarographic oxygen monitoring system from Instech Solomon

Description:The SYS203 is a complete, flexible system designed specifically for oxygen measurement in small samples, as is frequently required in biological research. The system is designed around Instechs miniature Clark-style polarographic electrode. Measuring only 1/8 of an inch in diameter (3.2 mm), it is ideal for metabolic studies of mitochondria, cell suspensions, and enzyme assays....
Company:Instech Solomon

Stand for Multichannel Pipettes from Thermo Scientific

Description:Request Info...
Company:Thermo Scientific

Model 1575 Immunowash and MICROTECH 12-Channel Manifold from Bio-Rad

Description:The Model 1575 immunowash microplate washer 100-240 V, is used for washing 96-well microplates that have flat-, U-, or V-bottom wells. The immunowash microplate washer has programmability of horizontal and vertical needle positions to an accuracy of 0.1 mm for bottom washing, crosswise aspiration, and overflow washing. It can store up to 75 wash sequences for customized protocols and includes a b...
Company:Bio-Rad

Mouse Anti-Calcium Channel alpha 2 delta-2 Monoclonal Antibody, Unconjugated, Clone 42 from BD Biosciences Pharmingen

Description:Calcium Channel alpha , 150 µg Consult technical datasheet for details....
Company:BD Biosciences Pharmingen

Perfusion Pressure Kit - 8 channel from AutoMate Scientific, Inc

Description:0-10 psi precision pressure regulator and pressurized syringe holder for any researcher who needs: Connect to hou...
Company:AutoMate Scientific, Inc

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Channel at Biology Technology

Verifying Multichannel Pipettor Performance with Standard Dispense Solutions in the SpectraMax Plus (MaxLine Application Note #28)

Pipettors often fail to meet the manufacturers stated specifications and pipetting is a major source of laboratory error even when the pipettor is operating properly. Accuracy and precision specifications typically provided by pipettor manufacturers are obtained under ideal conditions. In the laboratory, performan...

Merge eFilm Builds Distribution Channel

MILWAUKEE, WI - - has signed agreements with four European companies to resell or distribute Merge eFilm's FUSION RIS/PACS and eFilm Workstation solutions. These full-service healthcare solution firms will increase the availability of Merge eFilm's products and services throughout European healthcare organisat...

Multichannel Pipetting: How to Choose the Correct Pipettor

by Sari Mannonen, Pasi Nieminen, Jukka Kaasinen and Kati Andersin Multichannel pipettors are widely used in microplate work, includingserological testing, molecular biology, immunology assays, andpolymerase chain reaction (PCR). The explosion of specific markets suchas genome projects and drug discovery has further increased the use ofthe microplate. Because mic...
Channel at Biology Definition

Ion channel

proteins<...
Channel at Biology Dictionary

Ion channel

potential) by allowing the flow of ions down their electrochemical gradient...
Channel at Medicine News

Feeding channel created by malaria parasite - a new target for malaria treatments

Researchers have found pore-like holes in the membranes of red blood cells infected by the deadliest form of the malaria parasite. The parasite, Plasmodium falciparum, apparently uses these holes to supply itself with the nutrients it needs to grow and reproduce. The discovery may lead to the development of new treatments for malaria, a widespread and devastating disease. Mala...

A Call To Open Up The Channel Of Goodwill To Rescue The Dying Hearts

The plight of poor children with congenital heart diseases (CHD) here moved NRIs into donating// $200,000 at a fund-raiser dinner held in the US by a non-profit organization. About 40-50 NRIs have offered to sponsor a child each. Some of them are keen to sponsor a child or two every year According to medical reports, every year, nearly 200,000 children are born in India with CHD. Only...

PharmaVentures Exploits Fastest Growing Media Channel to Launch First Pharmaceutical Business Television Show

PharmaVentures today announces the launch of a brand new internet-based television show//: PharmaVentures Business Review. Dr Fintan Walton, CEO, PharmaVentures, says, ‘This show, the first in a monthly series, provides viewers across the pharmaceutical and biotechnology sectors with insightful analysis and debate covering major transactions and industry trends. It gives exclusive...

New Way to Open Cellular Ion Channels, Implications for Drug Design

Using an enzyme found in the venom of the brown recluse spider, researchers at the University of Pennsylvania School of Medicine have discovered a new way to open// molecular pores, called ion channels, in the membrane of cells. The research team – Zhe Lu, MD, PhD; Yajamana Ramu, PhD; and Yanping Xu, MD, PhD of the Department of Physiology at Penn – screened venoms from over 100 pois...

Altered Sodium Channel Function Linked to Heart Failure

The results of a study, using mice and heart muscle cells from rabbits, by researchers from Georg-August-University G?ttingen, Germany, have provided// a potential molecular explanation for the abnormally rapid heartbeats known as ventricular tachyarrhythmias (VTs) that can cause the sudden death associated with heart failure. Individuals who inherit mutations in genes regulating the...

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Channel at Medicine Products

MEDPOR Miniplate Channel Implant

Description:Medpor Channel Implants, designed to accept rigid fixation plates, provide the surgeon with an excellent reconstructive option for major orbital wall and floor blowout defects. Each design has several channels for placement of one or more rigid fixation plates by the surgeon....
Company:Porex Surgical Products Group

MEDPOR Barrier Miniplate Channel Implant

Description:Medpor Channel Implants, designed to accept rigid fixation plates, provide the surgeon with an excellent reconstructive option for major orbital wall and floor blowout defects. Each design has several channels for placement of one or more rigid fixation plates by the surgeon....
Company:Porex Surgical Products Group

8 Channel Elisa Plate Reader

Description:Plate Reader is an eight channel photometer for the sequential and simultaneous reading of micro-plate strips with 96 wells. High technology, user friendly, powerful and reliable....
Company:Geneq, Inc.

Flexible, steerable endoscope with working channel

Description:The flexible endoscope was mainly developed for the pure neuroendoscopy. Due to the working channel it is ideal suitable for therapeutic indications e.g. subdural hematomas, cysts or intraventricular indications....
Company:B. Braun Medical Inc.

BLF21 Single Channel

Description:Housed in a small lightweight, flame retardant plastic cases, meters are equipped with a convenient multiposition handle/stand. Measure microcirculation in 1 cubic mm of tissue for real-time assessment of perfusion....
Company:Transonic Systems, Inc.

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Channel at Medicine Technology

Calcium Channel Blocker Adalat GITS Offer Additional Benefits

ACTION-trial shows medical and economic advantages of nifedipineGITS therapy LEVERKUSEN, Germany, March 28, 2007 – Two recentlypublished articles in the Journal of Clinical Epidemiology providefurther evidence that the use of the long-acting calcium channelblocker (CCB) nifedipine GITS (Adalat? GITS) has additionalbenefits beyond its blood pressure lowing effec...
Channel at Medicine Dictionary
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(Date:10/11/2008)...ational Transcends Cultural Divides, JOHANNESBURG...can and,international audiences welcome Bishop T.D...ng gathering, which for the first time is being,he...//www.newscom.com/cgi-bin/prnh/20081011/CLSA011 )... with performances by,South Africa,s own multi-awa...
(Date:10/10/2008).../PRNewswire-FirstCall/ -- Synvista,Therapeutics, I...William,(Bill) Federici, 49, to its Board of Direc...ederici joined West Pharmaceutical Services as Vic...of 2003. Under his financial leadership,West Phar... billion from,$300 million. He has more than 20 ye...
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Breaking Medicine News(10 mins):Health News:Bishop T.D. Jakes Electrifies South Africa 2Health News:Synvista Therapeutics Appoints William Federici to its Board of Directors 2Health News:Synvista Therapeutics Appoints William Federici to its Board of Directors 3Health News:Video: Just What the Doctor Ordered: Survey Shows Americans Adopting Healthier Lifestyles 2Health News:Video: Just What the Doctor Ordered: Survey Shows Americans Adopting Healthier Lifestyles 3Health News:Deck of Cards is More Than a Game: Integral in Silverado Hospice Care 2
(Date:10/10/2008)... for Special Surgery researchers have found that s...n who are suffering from pregnancy complications c...g to a study in mice. In this autoimmune syndrome,...ipids, the main components of cell membranes. This...issue of the Journal of Clinical Investigation t...
(Date:10/10/2008)...DIANAPOLIS Investigators from the Herman B Wells ...rsity School of Medicine are focusing on a family ...ecreasing the toxic effects of chemotherapy in chi...help in the development of targeted therapies for ...e blood. , The researchers, led by Kristin T. Ch...
(Date:10/10/2008)...n, Conn. Yale scientists have created nanowire se...cs that are both sensitive and specific enough to ... according to a report in Nano Letters . , The ...pecific antigens signatures of bacteria, viruses ... activated, they produce acid, and generate a tiny...
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Breaking Biology News(10 mins):Statins may prevent miscarriages 2Statins may prevent miscarriages 3On the trail of a targeted therapy for blood cancers 2Sensitive nanowire disease detectors made by Yale scientists 2Synaptics to Report First Quarter Results on October 23 2Kmart Pharmacy Awards Its Transaction Processing Business to eRx Network 25676 1Kmart Pharmacy Awards Its Transaction Processing Business to eRx Network 25676 2FDA Grants Fast Track Designation for OncoGenex Pharmaceuticals Lead Product Candidate OGX 011 7283 1FDA Grants Fast Track Designation for OncoGenex Pharmaceuticals Lead Product Candidate OGX 011 7283 2FDA Grants Fast Track Designation for OncoGenex Pharmaceuticals Lead Product Candidate OGX 011 7283 3FDA Grants Fast Track Designation for OncoGenex Pharmaceuticals Lead Product Candidate OGX 011 7283 4Physician Recruiting Standard Reveals Larger Populations Experiencing Increased Doctor Shortage 25671 1Physician Recruiting Standard Reveals Larger Populations Experiencing Increased Doctor Shortage 25671 2Five Steps for Staying in Financial Control with Long Term Disability 25667 1Five Steps for Staying in Financial Control with Long Term Disability 25667 2Five Steps for Staying in Financial Control with Long Term Disability 25667 3Five Steps for Staying in Financial Control with Long Term Disability 25667 4
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