Cancer

Viral DNA sequence a possible trigger for breast cancer

A small sequence of DNA in the envelope (Env) protein of a mouse breast tumor virus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et al. in the February 7 issue of The Journal of Experimental Medicine. The ability of this motif to transform cells single-handedly suggests that viral infection may be an important and previously unrecognized trigger for bre...

Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer

For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...

Jump-starting T Cells In Skin Cancer

Advanced melanoma, the most deadly form of skin cancer, can be successfully treated in some cases by vaccinating patients with tumor proteins. How these vaccines work and why they are only effective in some patients remains unclear. Pierre Coulie and colleagues now show, in two articles in the January 17 issue of the Journal of Experimental Medicine, that these vaccines work by increasing the num...

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. is the system of defenses designed to protect the integrity of the genome. Studies have suggested that deficiency...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

In a finding that broadens our insight intothe cause of certain kinds of UV-induced skin cancer, researchers atErasmus University Medical Center (Rotterdam, The Netherlands) haveemployed an evolutionarily ancient enzyme-repair system to identify theprincipal type of DNA damage responsible for the onset of skin-tumordevelopment. The researchers' findings also suggest that this enzymesystem m...

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Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer

transgenicrodent mutation assay Centre for Environmental Health, University of Victoria, Victoria, BC Canada transgenic rodent mutationassay,* which carries the E. coli lacI transgene in a retrievabl...

Cancer siRNA Oligo Set Version 1.0

This comprehensive siRNA discovery tool allows gene-silencing studies of 139 human cancer-related genes for functional genomics research using RNAi. Cancer-related genes were chosen in collaboration with leading academic cancer researchers (see table below for a list of...

Detection of Mutant K-ras in a Kindred With Hereditary Pancreatic Cancer by DGGE

David A. Crispin,* Ru Chen,* Michael B. Kimmey,** Teresa A. Brentnall** * Departments of Pathology and **Medicine, Division of Gastroenterology, University of Washington, Seattle, Washington. Introduction Pancreatic cancer is the fourth leading cause of cancer death in the U.S....

Detection of p53 Gene in Breast Cancer by Denaturing Gradient Gel Electrophoresis and the DCode System

Tochigi Cancer Center, Tochigi, Japan Introduction Denaturing gradient gel electrophoresis (DGGE) is one of the most consistently used mutation scanning methods. It has evolved enormously over the last decade to be widely used particularly in gene diagnostic l...

Lance Armstrong and the future of cancer care

As many people know, survivors of cancer are much more common today. A recent National Center for Health Sta...

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Cancer at Biology Definition

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Cancer at Medicine News

Fibroids unlikely to Turn Cancerous

Women should get a second medical opinion if they are told to consider a hysterectomy because they have fibroid tumors that could become cancerous.//'It is very, very rare that a fibroid tumor could become cancerous,' said Dr. Nelson Teng, chief of gynecologic oncology at the Stanford University School of Medicine.Fibroids are benign growths in the uterus which sometimes cause discomfort,...

Virus Level could Predict Cervical Cancer Risk

Cervical cancer is one of the most common cancers in women. If it is caught and treated early, it is curable in most cases.// The Pap smear is the standard screening method for the disease. It is used to detect unusual, precancerous changes in cervical cells. Two strains of the human papilloma virus (HPV) are associated with an increased chance of getting the cancer, but not all women who tes...

Cancer Doctors Okays Controversial Prostate Therapy

A controversial treatment for prostate cancer in which radioactive seeds are implanted in the prostate to destroy the tumor received support Friday from doctors writing therapy guidelines for the prestigious 17-hospital National Comprehensive Cancer Network (NCCN) meeting in Ft. Lauderdale, Fla. This type of therapy is known as brachytherapy, the procedure has been performed for years by researc...

Potential New Cancer Gene Identified

A Johns Hopkins University research team has discovered a new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood cancer, Burkitt's lymphoma - as well as lymphoma, leukemia, prostate, ovarian, lung, and breast cancer. Characterized by rapidly growing abdominal tumors, Burkitt's lymp...

Vitamin B12 can help in detecting cancers

In some of the cancer patients the Tumors can't be easily deected. A new procedure being done at Mayo Clinic using vitamin B12 that helps doctors locate hard to find tumors. During the processes a patient is injected with radioactive vitamin B12. After three hours a gamma camera takes pictures of the body. Dr. Collins treated a patient with breast cancer and he says that, "The cancer stands out a...

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Cancer at Medicine Products

Breast Cancer Camera

Description:BCC (Breast Cancer Camera) a digital special purpose scintimammography camera. Offering ultra-high resolution, the ability to image to the edge of the detector and separate the breast from the chest wall, as well as breast containment and stabilization and stereotactic imaging for biopsy and surgery, IS2s breast scintimammography camera is a dedicated system with breast containment and stereotac...
Company:IS2 Medical Systems

Cancer Antigen 125 (Trademark of Fujirebio Diagnostic Inc.)

Description:Abbott offers an array of both in-vitro and molecular diagnostic tests for the detection and monitoring of cancerous conditions in patients....
Company:Abbott Diagnostics

Vysis UroVysion Bladder Cancer Kit

Description:The UroVysion Bladder Cancer Kit (UroVysion Kit) is designed to detect aneuploidy for chromosomes 3, 7, 17, and loss of the 9p21 locus via fluorescence in situ hybridization (FISH) in urine specimens from persons with hematuria suspected of having bladder cancer. Results from the UroVysion Kit are intended for use, in conjunction with and not in lieu of current standard diagnostic procedures, as...
Company:Abbott Diagnostics

Physicians' Cancer Chemotherapy Drug Manual 2005

Description:Completely revised and updated for 2005, this practical handbook is an up-to-date guide to all aspects of cancer chemotherapy. The book provides a comprehensive, easy to use catalog of over 100 drugs both on and off label commonly used in cancer treatment. This new edition includes new agents (recently or about to be FDA approved)....
Company:Skyscape, Inc.

Pocket Guide to Colorectal Cancer Drugs and Treatment

Description:Focuses primarily on the drugs used for treatment and symptom management for colorectal cancer....
Company:Skyscape, Inc.

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Cancer at Medicine Technology

Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy

Contributing Editor With over 200,000 new cases and 40,000 deaths per year, breast cancer undoubtedly qualifies as one of Americas most serious health problems. Recently, efforts to develop early detection methods and more effective therapy have made important progress. This is particularly...

Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer

NEW YORK, July 12, 2007 /PRNewswire-FirstCall/ -- ImCloneSystems Incorporated and Bristol-Myers Squibb Company todayannounced results from an open-label Phase III study of ERBITUX(R)(Cetuximab) plus a taxane and carboplatin in the first-linetreatment for metastatic non-small cell lung cancer (NSCLC). Thestudy did not meet its primary endpoint of progression-freesurvival (PFS) as assessed...

Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs

IRVING, Texas--(BUSINESS WIRE)--Jul 11, 2007 - The Journal of theAmerican Society of Clinical Oncology has published the earlyresults of a clinical study conducted by Dr. Siu-Fun Wong, and hercolleagues, which concluded that the topical gel, Regenecare(R),caused a statistically significant reduction in the pain anditching of a rash that results from the use of anti-cancer drugsknown as EGFR...

Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial

LONDON, 12 July 2007 - Cancer drug developer Antisoma plc(LSE: ASM, US OTC: ATSMY) today announces new data from its phaseII trial of ASA404 in recurrent, platinum-sensitive ovarian cancer.This trial compares patients receiving ASA404 plus chemotherapy(n=37) with patients receiving chemotherapy alone (n=38). The mainfindings are as follows: * There was no advantage in median time t...

Protox Announces Positive Clinical Data from Prostate Cancer Study

VANCOUVER, British Columbia, July 10, 2007 /CNW/ - ProtoxTherapeutics Inc. (TSX-V:PRX) today announced positivetop-line results from its Phase 1 clinical trial evaluating PRX302 in patients with localized, recurrent prostate cancerfollowing radiation failure. The trial results indicate thatPRX302 is safe and well tolerated and shows promising signsof therapeutic activity following a s...

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Cancer at Medicine Definition

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