Viral DNA sequence a possible trigger for breast cancer
A small sequence of DNA in the envelope (Env) protein of a mouse breast tumor virus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et al. in the February 7 issue of The Journal of Experimental Medicine. The ability of this motif to transform cells single-handedly suggests that viral infection may be an important and previously unrecognized trigger for bre...New push for public health, AIDS spending at African Union summit
Activists hope this weekend's African Union (AU) summit will net commitments to boost government spending on public health, helping to curb the spread of AIDS, which killed 2.3 million Africans in 2004. "We are definitely optimistic that this time there will be some movement, that this time there will be not just talk about an HIV strategy for the AU but how to tackle an action-oriented p...Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...Jump-starting T Cells In Skin Cancer
Advanced melanoma, the most deadly form of skin cancer, can be successfully treated in some cases by vaccinating patients with tumor proteins. How these vaccines work and why they are only effective in some patients remains unclear. Pierre Coulie and colleagues now show, in two articles in the January 17 issue of the Journal of Experimental Medicine, that these vaccines work by increasing the num...Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer
Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. is the system of defenses designed to protect the integrity of the genome. Studies have suggested that deficiency...Canine Pancreatic Microsomal Membranes from Promega
Description:Microsomal vesicles are used to study co-translational and initial post-translational processing of proteins. Processing events such as signal peptide cleavage, membrane insertion, translocation and core glycosylation can be examined by the translation of the appropriate mRNA in vitro in the presence of these microsomal membranes. In addition, processing and glycosylation events may be studied by...Canine Endostatin EIA Kit from Neogen Corporation
Description:Detection of Total Canine Endostatin. Canine Cytokine EIA Kits(Competitive Format) Neogens Life Science products include a line of enzyme-linked immunosorbent assay (ELISA) test kits and reagents used for multiple research applications. The line of ELISA test kits are ultra-sensitive, quick and dependable assays. The quantitative test kits detect hormones, steroids, prostaglandins, le...GenePix Autoloader 4200AL Microarray Scanner from Molecular Devices
Description:The GenePix Professional 4200A can be upgraded to the GenePix Autoloader 4200AL. The GenePix Autoloader automatically loads, scans, analyzes, and saves results for up to 36 slides, then notifies you by email when the batch is complete. Line-by-line autofocus ensures superior field uniformity, even for warped slides. GenePix Pro gives you complete flexibility to configure scanning and analysis par...Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer
transgenicrodent mutation assay Centre for Environmental Health, University of Victoria, Victoria, BC Canada transgenic rodent mutationassay,* which carries the E. coli lacI transgene in a retrievabl...Ergonomics and Liquid Handling How can BrinkmannTM Help ?
How can Brinkmann As a laboratory technician, pipetting is a routine laboratory technique that is performed everyday, for a good portion of the day. Pipetting work demands concentration, accuracy and preci...Cancer siRNA Oligo Set Version 1.0
This comprehensive siRNA discovery tool allows gene-silencing studies of 139 human cancer-related genes for functional genomics research using RNAi. Cancer-related genes were chosen in collaboration with leading academic cancer researchers (see table below for a list of...Enhancing Ruggedness and Full-Scan MS Sensitivity Using Ion Sweep Technology
RohanA.Thakur, AndrewW. Guzzetta, and Julie A.Horner The data presented here can be acquired using a Thermo Finnigan LCQ Advantage, LCQ Deca XP, and Deca XP Plus ion trap mass spectrometer....Detection of Mutant K-ras in a Kindred With Hereditary Pancreatic Cancer by DGGE
David A. Crispin,* Ru Chen,* Michael B. Kimmey,** Teresa A. Brentnall** * Departments of Pathology and **Medicine, Division of Gastroenterology, University of Washington, Seattle, Washington. Introduction Pancreatic cancer is the fourth leading cause of cancer death in the U.S....Fibroids unlikely to Turn Cancerous
Women should get a second medical opinion if they are told to consider a hysterectomy because they have fibroid tumors that could become cancerous.//'It is very, very rare that a fibroid tumor could become cancerous,' said Dr. Nelson Teng, chief of gynecologic oncology at the Stanford University School of Medicine.Fibroids are benign growths in the uterus which sometimes cause discomfort,...Virus Level could Predict Cervical Cancer Risk
Cervical cancer is one of the most common cancers in women. If it is caught and treated early, it is curable in most cases.// The Pap smear is the standard screening method for the disease. It is used to detect unusual, precancerous changes in cervical cells. Two strains of the human papilloma virus (HPV) are associated with an increased chance of getting the cancer, but not all women who...Cancer Doctors Okays Controversial Prostate Therapy
A controversial treatment for prostate cancer in which radioactive seeds are implanted in the prostate to destroy the tumor received support Friday from doctors writing therapy guidelines for the prestigious 17-hospital National Comprehensive Cancer Network (NCCN) meeting in Ft. Lauderdale, Fla. This type of therapy is known as brachytherapy, the procedure has been performed for years by...Epileptic Seizures Can Be Duec to Heart Problem
British researchers have said that Many people thought to have epilepsy may have a heart problem instead. In a study, researchers closely examined people diagnosed with epilepsy who did not respond well to medication or had symptoms unusual for the disorder. They found that more than 40% had another medical problem--most often a heart or circulation condition--that could have caused the s...Potential New Cancer Gene Identified
A Johns Hopkins University research team has discovered a new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood cancer, Burkitt's lymphoma - as well as lymphoma, leukemia, prostate, ovarian, lung, and breast cancer. Characterized by rapidly growing abdominal tumors, Burkitt's lymp...Microsurgical Cannula Holder Tray
Description:Anodized aluminum. Durable and lightweight with built-in protection against rust. Security locks ensure against accidental opening. Silicone matting/V-strips and bumper guards hold instruments in place. Sturdy, long wearing, riveted hinges....Vitreoretinal Injection Cannula
Description:20 gauge x 25 mm cannula with 30 degree x 5 mm tip. 30 gauge cannula extends into hub 2 mm from end of hub. 10 per box....Vitreoretinal Injection Cannula - Angled
Description:Angled, 20 gauge x 25 mm cannula with 30 gauge x 5 mm tip. 30 gauge cannula extends into hub 2 mm from end of hub, angled 45 degrees 2.5 mm from tip. 10 per box....Silicone Oil Cannula System - 20 Gauge
Description:20 gauge x 8 mm with 15 cm high pressure extension tube preattached to a 10C ring control syringe. 3 per box....West Nile Virus Screening and Diagnostics Technology Emerges In Step with North American Outbreak
WNVis a positive single-stranded RNA flavivirus of about 11 kb. It primarily infe...Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy
Contributing Editor With over 200,000 new cases and 40,000 deaths per year, breast cancer undoubtedly qualifies as one of Americas most serious health problems. Recently, efforts to develop early detection methods and more effective therapy have made important progress. This is particularly...Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
NEW YORK, July 12, 2007 /PRNewswire-FirstCall/ -- ImCloneSystems Incorporated and Bristol-Myers Squibb Company todayannounced results from an open-label Phase III study of ERBITUX(R)(Cetuximab) plus a taxane and carboplatin in the first-linetreatment for metastatic non-small cell lung cancer (NSCLC). Thestudy did not meet its primary endpoint of progression-freesurvival (PFS) as assessed...Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
LONDON, 12 July 2007 - Cancer drug developer Antisoma plc(LSE: ASM, US OTC: ATSMY) today announces new data from its phaseII trial of ASA404 in recurrent, platinum-sensitive ovarian cancer.This trial compares patients receiving ASA404 plus chemotherapy(n=37) with patients receiving chemotherapy alone (n=38). The mainfindings are as follows: * There was no advantage in median time t...European Prospective Investigation into Cancer and Nutrition
and <a href="/ ?q=...Canadian Health Libraries Association
librarians...