Inside Myanmar: California Relief Organization Bypasses Bureaucratic Barriers, Has Aid Workers in Myanmar

NEVADA CITY, Calif., May 11 /PRNewswire/ -- The Myanmar Relief Fund ( http://www.MyanmarReliefFund.org ) is a coalition of private American and Myanmar citizens that have the know-how to get aid in and directly to the victims bypassing bureaucratic barriers. Teams of doctors are treating the i...

Screening bypasses radical breast surgery

According to researchers at the Britain University, breast screening is linked with a fall of almost half in the number of mastectomies. A team working for the leading charity Cancer Research UK// has analyzed data from a group of 55,000 women in Florence, Italy, aged between 55 and 65. They find t...

Older Men Surviving Coronary Bypasses

The survival rate for older men undergoing coronary artery bypass surgery is rising, even though more patients than ever are undergoing the procedure.// Coronary artery bypass surgery uses a blood vessel from another part of the body to reroute blood around narrowed or clogged arteries in the heart...

Eliminating Cell Receptor Prevents Infections in Animal Study

...s in humans or animals, but without binding to the cellular receptors identified in cultured cells. For instance, adenovirus infects the liver, but it bypasses identified adenovirus receptors in that organ. Instead the virus engages in complicated interactions with blood proteins and unidentified molecules in...

Vein Removal Method Linked to Bypass Results

...ry, which requires a much longer incision, is used in the other 30 percent of cases. Endoscopic harvesting is popular among surgeons and people having bypasses because it virtually eliminates the risk of infection, excess bleeding and other complications associated with conventional removal. The journal re...

DNA-damaged cells communicate with neighbors to let them know they're in trouble

...that there's a problem," said Rodier. He added that scientists were also surprised to discover that the damage-induced communication signaling pathway bypasses a powerful tumor suppressor gene known as p53. That finding gives scientists a target to shut down the inflammatory process without hampering the acti...

Watson Launches GELNIQUE(TM) (oxybutynin chloride) Gel 10%, First and Only Topical Gel for Overactive Bladder (OAB)

... Because the active ingredient in GELNIQUE is delivered transdermally, it is not metabolized in the same way as orally administered oxybutynin. It bypasses fist-pass metabolism, which reduces the formation of the N-desethyloxybutynin metabolite (N-DEO), which may be linked to unwanted side effects such as...

Old diabetes drug teaches experts new tricks

...abetes in the 1950s, up until now was believed to work by making the liver more sensitive to insulin. The Hopkins study shows, however, that metformin bypasses the stumbling block in communication and works directly in the liver cells. "Rather than an interpreter of insulin-liver communication, metformin ...

New Data Presented at AUA's Annual Conference Prove GELNIQUE(TM) (oxybutynin chloride) 10% gel is an Effective, Safe Option for Female Overactive Bladder (OAB) Patients

... Because the active ingredient in GELNIQUE is delivered transdermally, it is not metabolized in the same way as orally administered oxybutynin. It bypasses fist-pass metabolism, which reduces the formation of the N-desethyloxybutynin metabolite (N-DEO), which may be linked to unwanted side effects such as...

FDA Fails to Consider Risks of Over-the-Counter Plan B

...n with medical professionals is a major screening and defense mechanism for victims of sexual abuse. The availability of Plan B over-the-counter also bypasses the necessary routine medical care of sexually active girls and women, which is important for the screening of health conditions, and for providing sc...

bypasses in Medical Technology

Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology

...rd Jacob, Ph.D. Director of the Human and Molecular Genetics Center at the Medical College of Wisconsin. "This study demonstrates that ZFN technology bypasses the current need to conduct cumbersome experiments involving nuclear transfer (cloning) or embryonic stem cells and allows rapid creation of new anima...

Novel Vaccine Approach Offers Hope in Fight Against HIV

...wire/ -- A research team may have broken the stubborn impasse that has frustrated the invention of an effective HIV vaccine, by using an approach that bypasses the usual path followed by vaccine developers. By using gene transfer technology that produces molecules that block infection, the scientists protecte...

ADVENTRX Announces CoFactor(R) Phase 2b Clinical Trial Overall Survival Results

...l). Compared to leucovorin, CoFactor creates more stable binding between the active form of 5-FU and the target enzyme, thymidylate synthase. CoFactor bypasses the metabolic pathway required by leucovorin to deliver the active form of folate, potentially allowing 5-FU to work more effectively. About ADVENTR...

ADVENTRX Presents CoFactor Data at the 2008 Annual Meeting of the American Society of Clinical Oncology (ASCO)

...l). Compared to leucovorin, CoFactor creates more stable binding between the active form of 5-FU and the target enzyme, thymidylate synthase. CoFactor bypasses the metabolic pathway required by leucovorin to deliver the active form of folate, potentially allowing 5-FU to work more effectively. About ADVENTR...

ADVENTRX to Present CoFactor Phase 2 Breast Cancer Data at the 2008 Annual Meeting of the American Society of Clinical Oncology (ASCO)

...l). Compared to leucovorin, CoFactor creates more stable binding between the active form of 5-FU and the target enzyme, thymidylate synthase. CoFactor bypasses the metabolic pathway required by leucovorin to deliver the active form of folate, potentially allowing 5-FU to work more effectively. About ADVENTR...

ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer

...In comparison to leucovorin, CoFactor creates more stable binding of the active form of 5-FU to the target enzyme, thymidylate synthase (TS). CoFactor bypasses the metabolic pathway required by leucovorin to deliver the active form of folate, allowing 5-FU to work more effectively. CoFactor is in Phase 3 and ...

ADVENTRX to Present CoFactor Multiagent Therapy Data at AACR Annual Meeting

...omparison to leucovorin, CoFactor creates more stable binding of the active form of 5-FU to the target enzyme, thymidylate synthase (TS). CoFactor bypasses the metabolic pathway required by leucovorin to deliver the active form of folate, allowing 5-FU to work more effectively. CoFactor is in Phase ...

Adventrx Announces Positive Data From Multidrug Therapy With CoFactor

...In comparison to leucovorin, CoFactor creates more stable binding of the active form of 5-FU to the target enzyme, thymidylate synthase (TS). CoFactor bypasses the metabolic pathway required by leucovorin to deliver the active form of folate, allowing 5-FU to work more effectively. CoFactor is in Phase 3 and ...

Study Supports Cost-Effectiveness of Medtronic's Spasticity Treatment for Children with Cerebral Palsy

...argeting the spinal cord, ITB Therapy reduces spasticity with smaller amounts of medication than would be required orally. Intrathecal infusion, which bypasses the body's blood-brain barrier, also minimizes systemic side-effects. ITB Therapy drug side effects are usually temporary and manageable by adjustin...

Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy

...A). ELISA is also available to quantify Her-2/neu expression. In contrast to IHC and FISH, ELISA can detect Her-2/neu as a serum marker. This bypasses the need for a tissue specimen and may allow earlier Her-2/neu detection. The Her-2/neu ELISA (Bayer Diagnostics Oncogene Science) is a sandwich-type...

bypasses in Biological News

New route for heredity bypasses DNA

A group of scientists in Princeton's Department of Ecology and Evolutionary Biology has uncovered a new biological mechanism that could provide a clearer window into a cell's inner workings. What's more, this mechanism could represent an "epigenetic" pathway -- a route that bypasses an organis...

Spinal cord bridge bypasses injury to restore mobility

The body's spinal cord is like a super highway of nerves. When an injury occurs, the body's policing defenses put up a roadblock in the form of a scar to prevent further injury, but it stops all neural traffic from moving forward. Researchers from Case Western Reserve University, Drexel Univ...

Probiotics help gastric-bypass patients lose weight more quickly, Stanford study shows

...students at the Surgery Center for Outcomes Research and Evaluation in Stanford's Department of Surgery. Morton has performed more than 1,000 of these bypasses at Stanford Hospital & Clinics. The researchers followed 44 patients on whom Morton had performed the procedure from 2006 to 2007. Patients were ra...

Study finds DNA barcoding requires caution without closer examination

... The goal of DNA barcoding is to find a simple, cheap, and rapid DNA assay that can be converted to a readily accessible technical skill that bypasses the need to rely on highly trained taxonomic specialists for identifications of the world's biota. This is driven by a desire to open taxonomic identi...

Novel vaccine approach offers hope in fight against HIV

... A research team may have broken the stubborn impasse that has frustrated the invention of an effective HIV vaccine, by using an approach that bypasses the usual path followed by vaccine developers. By using gene transfer technology that produces molecules that block infection, the scientists protecte...

CSHL researchers pinpoint structure-building role for 2 non-coding RNAs

...-made RNAs in the paraspeckles and releasing them during times of need speeds the cell's response to stress by about 25 minutes, in certain cases, and bypasses the cell's need to prepare the RNA from scratch. "Paraspeckles might be part of the cell's rapid response mechanism to stress," says Spector. "It ...

Similar survival rates for Pacific salmon in Fraser, Columbia Rivers raises new questions

... team to gather data on salmon smolts in the Fraser River. Before that, it was only possible to measure juvenile survival where salmon gathered in dam bypasses like those in the Columbia and Snake Rivers. The lower Columbia and lower Snake Rivers currently have eight major hydroelectric dams combined. Duri...

Normal-looking sperm may have serious damage; scientists urge more care in selection

... Sperm biology has received less attention since the introduction and success of the ICSI technique, say the researchers. "While the ICSI procedure bypasses the natural sperm selection, we believe that the deleterious effects of injecting a DNA-fragmented sperm should and can be avoided. Further research i...

New twist on life's power source

... has solved the iron problem, at least in part, by short-circuiting the standard photosynthetic process, says Grossman. Much of the time this organism bypasses stages in photosynthesis that require the most iron. As it turns out, these are also the stages in which carbon dioxide is taken from the atmosphere....

'Generalist bacteria' discovered in coastal waters may be more flexible than known before

...tremely difficult. New methods, however, are making such studies easier. One of them, which formed the basis for this research, is metagenomics, which bypasses the culturing step entirely by directly sequencing the mixture of bacterial genomes in seawater. Understanding more about the genomes of bacteria ...

bypasses in Biological Technology

Results From Neurotech's NT-501 Phase 2 Retinitis Pigmentosa Studies Demonstrate Consistent Biological Effect on Photoreceptors

...back of the eye in a controlled, continuous basis by means of the Company's proprietary Encapsulated Cell Technology (ECT) platform. Delivery via ECT bypasses the blood-retinal barrier and overcomes a major obstacle in the treatment of retinal disease. The two Phase 2 studies were multi-centered, rando...

Towards zero training for brain-computer interfacing

... ONE , on August 13, a new study by Matthias Krauledat and colleagues at the Berlin Institute of Technology suggests a novel data analysis method that bypasses the need for the time-consuming calibration for long-term BCI users and may reduce the calibration time from 20?? minutes to one minute. This is achie...

Super-resolution X-ray microscopy

...on images, but usually only for the surface of the specimen, and the samples must be kept in vacuum. The Swiss team's new super-resolution microscope bypasses these requirements, meaning that scientists will now be able to look deeply into semiconductors or biological samples without altering them. It can be...

PTC124 Featured at Third Annual Congress of Myology

...brosis (CF), are caused by genetic alterations, known as mutations. By targeting a specific type of genetic alteration -- nonsense mutations -- PTC124 bypasses the defect and leads to the restoration of a functional protein. The company has catalogued over 2,400 distinct genetic disorders for which nonsense m...

Fate Therapeutics Created by Leading Stem Cell Scientists to Pursue New Approaches to Stem Cell Therapies

...ersity of Washington, the Scripps Research Institute, and Massachusetts General Hospital partner with top investor groups Technology bypasses current debate on ethical use of embryonic stem cells by using pharmaceutical medicines to modulate stem cells inside the body and via the...

Sigma-Aldrich Introduces N-TER Nanoparticle siRNA Transfection System for Delivery of siRNA Into Difficult-to-Transfect Cell Types

... Fleming, Director of Global Commercial Marketing at Sigma-Aldrich. "Our goal is to introduce a reagent into the scientific community that effectively bypasses these historic limitations and enables siRNA transfection to be performed in a wider variety of model systems." The N-TER Nanoparticle siRNA Transfec...

ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer

...In comparison to leucovorin, CoFactor creates more stable binding of the active form of 5-FU to the target enzyme, thymidylate synthase (TS). CoFactor bypasses the metabolic pathway required by leucovorin to deliver the active form of folate, allowing 5-FU to work more effectively. CoFactor is in Phase 3 and ...

Polymer grid technology a boon for bridges

...k replacement. "The idea is, if you have to do a deck replacement on a busy road like I-90, you want to do it as quickly as possible so you don't have bypasses that are dangerous, or detours, which are even worse," says Bank. The FRP grid system is the first of its kind installed anywhere, thanks to fundi...

Cancer-fighting agent heads for clinical trials

... tumor cell resistance to gallium nitrate is not well understood, but Chitambar's research has found gallium maltolate to be a unique formulation that bypasses the cellular pathways involved in gallium resistance. It is able to deliver gallium to molecules within the cell that are involved in inducing cell de...

Optimizing siRNA Transfection for RNAi

...ls, much like procedures used for transfecting suspension cells. This method is easier and faster because it bypasses several steps of the traditional procedure. This article summarizes the use of reverse transfection to maximize ...

bypasses in Biological Definition

Outbreak

... Virus outbreaks occur when a virus bypasses infection control measures and a relatively high number of infections are observed where no cases or sporadic cases occurred in the past. The study o...

bypasses in Biological Dictionary

Shotgun sequencing

...ing : Sample Submission Requirements ... Brief and Straightforward Guide: What is Shotgun Sequencing ? ... Whole genome shotgun sequencing bypasses the creation and mapping of BACs and ... Shotgun sequencing summary with 7 pages of encyclopedia entries, essays, summaries, research informa...