Blocking

UCSD study clarifies insulin's role in blocking release of energy in patients with type II diabetes

Chronically high levels of insulin, as is found in many people with obesity and Type II diabetes, may block specific hormones that trigger energy release into the body, according to researchers at the University of California, San Diego (UCSD) School of Medicine. Their findings, which may point to new approaches to developing improved treatment options for the disease, will be published in the Se...

Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke

Researchers at Johns Hopkins have discovered how to block a molecular switch that triggers brain damage caused by the lack of oxygen during a stroke. The Hopkins study, conducted on mice, is believed to be the first to demonstrate that a protein on the surface of nerve cells called the EP1 receptor is the switch, and that a specific compound, known as ONO-8713, turns it off. The finding...

Selectively blocking inflammatory signals may protect mice from MS

A new way to preserve the cells that surround and protect nerves could lead to new treatments for demyelinating diseases such a multiple sclerosis, a research team reports in the May 10, 2006, issue of the Journal of Neuroscience. The approach grew out of a novel explanation, quickly gaining followers, for the mechanism of nerve damage caused by multiple sclerosis. Instead of concentratin...

Signal protein shows promise for blocking tumor promoters in skin cells

A protein with the ironic name "Srcasm" can counteract the effects of tumor-promoting molecules in skin cells, according to new research by investigators at the University of Pennsylvania School of Medicine. Using animal models, the researchers discovered that Srcasm acts like a brake in epithelial cells, preventing uncontrolled cell growth caused by a family of proteins called Src kinases. This...

Blocking immune cell action increases Alzheimer's-associated protein deposits

The immune system's response against amyloid-beta, the protein that forms plaques in the brains of patients with Alzheimer's disease, appears to protect the brain from damage in early stages of the devastating neurological disorder. A report from Massachusetts General Hospital (MGH) researchers finds that lack of a protein required for recruitment of the brain's primary immune cell led to increa...

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Blocking at Biology Products

BlockAid blocking solution *for use with microspheres* from Molecular Probes (Invitrogen)

Description:Molecular Probes intensely fluorescent and highly photostable FluoSpheres microspheres have enormous potential for use in a variety of applications requiring probes that can deliver a strong signal. Unfortunately, protein- and other macromolecule-labeled microspheres have hydrophobic regions that may cause them to bind to non-target surfaces in some applications. This nonspecific binding can be r...
Company:Molecular Probes (Invitrogen)

Guanylate Cyclase Blocking Peptide from Cayman Chemical

Description:To be used in conjunction with Cayman's guanylate cyclase polyclonal antiserum (Catalog No. 160890) to block protein-antibody complex formation during analysis for guanylate cyclase....
Company:Cayman Chemical

EP1 Receptor Blocking Peptide from Cayman Chemical

Description:Each vial contains 200 g of lyophilized peptide derived from the human EP1 receptor sequence (C-terminal amino acids 380-402; GLTPSAWEASSLRSSRHSGLSHF. This peptide was used as an antigen for production of Cayman's EP1 receptor polyclonal antibody (Catalog No. 101740) and can be used in conjunction with this antibody to block protein-antibody complex formation during analysis for the EP1 rece...
Company:Cayman Chemical

COX-1 Blocking Peptide from Cayman Chemical

Description:To be used in conjunction with Cayman's COX-1 (ovine) polyclonal antiserum (Catalog No. 160108) to block protein-antibody complex formation during analysis for COX-1....
Company:Cayman Chemical

Blocking Reagent, TBS with 1% BSA from Bethyl Laboratories

Description:Request Info...
Company:Bethyl Laboratories

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Blocking Pain Found To Slow Down The Healing Process

Researchers say standard post-operative pain medications widely prescribed for rotator cuff surgery may actually delay healing .// The rotator cuff is composed of the muscles and tendons that surround the top of the upper arm bone and hold it to the shoulder joint. The research involved 180 rats that received acute rotator cuff repair surgery. One-third of the rats were treated with ind...

HIV blocking protein in Monkey

Scientists at the Dana-Farber Cancer Institute have identified a protein that essentially blocks HIV replication, in monkey cells. Humans have a similar protein, although it is not as effective at stopping HIV, say the researchers whose work //is published in this week's issue of Nature. The team, headed by Joseph Sodroski, is supported by the NIH's National Institute of Allergy and Infectious Di...

Improving The Survival Of Lung Cancer Patients By Blocking The Effects Of Estrogen

Stopping or slowing the spread of lung cancer may depend on the addition of drugs that block the effects of estrogen, // say researchers according to a recent study . For the study researchers evaluated the effects of three different treatments that block the action of estrogen in human lung tumors grafted in mice. They studied the effectiveness of an estrogen receptor-blocking drug (ful...

Protein Fragments Blocking Cures Alzheimer's Disease

Professor Yadong Huang and his team from Gladstone Institute of Neurological Disease have found that the protein apolipoprotein E (apoE) is responsible for causing Alzheimer's disease //that acts by inactivating the conversion of glucose into energy in Mitochondirial cells due to the protein fragments released from apoE. The apoE protein is found to be responsible for causing Alzheime...

Multiple Sclerosis Can Be Treated By Blocking Fat Hormone

The blocking of the leptin hormone which is mostly produced in fats cells has a good effect with regard to multiple sclerosis (MS), according to// Italian researchers. Giuseppe Matarese and colleagues from Università di Napoli "Federico II" suggest that leptin neutralization may be a possible way to both prevent and treat MS. Leptin is known to play a critical role in the regulation...

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Blocking at Medicine Products

Dorsal Blocking Splint

Description:The RCAI Dorsal Blocking Splint is constructed of a durable heat moldable thermoplastic for patient customization. The DBS protects the flexor tendons of the hand and fingers from stress following injury, and prevents scar tissue development in the later stages of the healing process. The DBS rest dorsally on the hand and positions the wrist at 30° of flexion, the MCP joints at 70&d...
Company:Restorative Care of America

Acetylcholine Receptor (AChR) Blocking Autoantibody RIA

Description:RIA kit for the determination of blocking autoantibodies to the acetylcholine receptor (AChR) in serum...
Company:KRONUS

Acetylcholine Receptor Blocking Antibody

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Intrinsic Factor Blocking Antibody

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Blocking at Medicine Technology

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