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Variation in women's X chromosomes may explain differences among individuals, between sexes

The first comprehensive survey of gene activity in the X chromosomes of women has revealed an unexpected level of variation among individuals, according to new work by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and Pennsylvania State University. The results may have important implications for understanding the differences in traits among women and...

Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.

Clams, mussels and oysters are important vehicles for the transmission of enteric diseases when consumed raw or undercooked. Vibrio species, including human pathogens, are particularly abundant in bivalve tissues, where they can persist even after cleaning procedures, thus representing a potential risk for human health. Although different environmental factors are well known to affect the persist...

Study reveals dramatic difference between breast cancers in US and Africa

A study comparing, for the first time, breast cancers from Nigeria, Senegal and North America has found that women of African ancestry are more likely to be diagnosed with a more virulent form of the disease than women of European ancestry. Researchers from the University of Chicago, working with colleagues at the University of Calabar in Nigeria and the University of North Carolina, foun...

Molecular fossils uncover link between viruses and the immune system

Researchers from the Viikki Biocenter, University of Helsinki, show that atomic structures can reveal evolutionary history of viruses in a similar fashion as fossils did for the dinosaurs and reptiles. Their article is published in the April 15 issue of Molecular Cell. These "molecular fossils" also revealed that viruses and proteins of immune system share the same structure. One plausibl...

Research may provide new link between soft drinks and weight gain

A University of Cincinnati (UC) study provides new evidence that drinking large amounts of beverages containing fructose adds body fat, and might explain why sweetening with fructose could be even worse than using other sweeteners. Researchers allowed mice to freely consume either water, fructose sweetened water or soft drinks. They found increased body fat in the mice that drank the fruct...

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PCR Performance Comparisons Between pfuturbo and Taq DNA Polymerases

pfuturbo DNA polymerase is the superior choice for robusthigh-fidelity PCR amplification Stratagene In this update, we compare the PCR performances of pfuturbo DNApolymerase * ,</...

Japan, Midwest Biotechnology Industry Leaders Identify Steps for Greater Collaboration Between Countries

CHICAGO,IL--Top industry, government and academic leaders in the biotech and life science industries from the Midwest U.S. and Japan gathered Wednesday in Chicago as part of the JETRO Midwest-Japan Biotechnology Summit. The topics covered similarity of challenges faced by Midwest Biotech companies and their counterparts in Japan. The goal was to foster discussion and lay down specific p...

Quantitative Measurement of Cell Proliferation Using the BrdU ELISA: A Comparison Between Colorimetric and Chemiluminescent Detection

Quantitative determination of DNA synthesis in cellcultures is now a routine procedure in many laboratories.Protocols are available for various applications,especially in cell culture systems. The effects of growthfactors, inhibition of cell division by exogenous factor...

Monitoring fluorescence resonance energy transfer (FRET) between GFP fusions in lysates of the yeast Saccharomyces cerevisiae using the Varian Cary Eclipse

fusions in lysates of the yeast Saccharomyces cerevisiae using the Varian Cary Eclipse Department of Biochemistry and Molecular Biol...

Comparison of Performance between the AlphaQuest - HTS and the Fusion α Multilabel Reader for Detection of cAMP

Kelly Carter-Allen and Loraine Upham PerkinElmer Life Sciences, Inc. technology is a highly sensitive, non-isotopic homogenous assay method developed for assay development and high throughput screening applications. PerkinElmer Life Sc...

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CDC reveals relationship between prepregnant weight and heart defects in infants

Keeping fit and in to be in shape is not only good for the individuals themselves but also for their siblings. Over weight, which is of course the predisposer of majority of the illness such as diabetes, heart disease, hypertension etc., is now being studied in depth, the reason is to attain the destination of disease free environment, that are preventable.// Researchers from the US Cent...

Link between Constipation and Parkinson's Disease

Researhers have found from a long-term study that men who suffer from constipation are nearly three times more likely to eventually develop Parkinson's disease. According to Robert Frank, Professor of Biostatistics and Statistics at the University of Texas School of Medicine, the connection between constipation and Parkinson's was noted almost 2 centuries back from a clinical study.<...

The Link Between Hepatitis B Vaccine And Multiple Sclerosis Questioned

A recent study by Harvard researchers suggests a link between the hepatitis B vaccination and multiple sclerosis. In their study, people who received the vaccine were three-times more likely to develop MS // over the next three years than those who were not vaccinated. While this finding is disturbing, the investigators emphasize the overall effect of the vaccine on the development of MS...

The Link Between Pregnancy and Restless Legs Syndrome

New research shows that pregnant women are at a higher risk of developing restless legs syndrome. Restless legs syndrome is marked by // an urge to move the legs and is generally accompanied by unpleasant numbness, tingling or burning sensations. Patients also report an increase in symptoms during rest, a partial, temporary relief from symptoms through activity, and a worsening of symptom...

The Link Between Pregnancy and Restless Legs Syndrome

New research shows that pregnant women are at a higher risk of developing restless legs syndrome. Restless legs syndrome is marked by // an urge to move the legs and is generally accompanied by unpleasant numbness, tingling or burning sensations. Patients also report an increase in symptoms during rest, a partial, temporary relief from symptoms through activity, and a worsening of symptom...

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Interim Data From RECORD Study Show No Significant Difference Between Avandia and Standard Therapy in Risk of Cardiovascular Hospitalization or Death

"Patients and physicians should find these data reassuring" PHILADELPHIA, June 05, 2007 /PRNewswire-FirstCall/ --GlaxoSmithKline said today that findings from an interim analysisof RECORD (Rosiglitazone Evaluated for Cardiac Outcomes andRegulation of glycemia in Diabetes), a prospective clinical trialdesigned specifically to determine cardiovascular outcomes in morethan 4,400 patients wit...

Topline Results of Phase III Study in Acute Ischemic Stroke (Dias-2) Do Not Demonstrate Difference Between Desmoteplase and Placebo

NEW YORK, May 31, 2007 /PRNewswire-FirstCall/ -- ForestLaboratories, Inc. and PAION AG today announced topline results ofthe DIAS-2 (Desmoteplase In Acute Ischemic Stroke) study with thecompound Desmoteplase. The Phase III study was designed toinvestigate the improvement of clinical outcome in patients withacute ischemic stroke treated with Desmoteplase within 3 to 9 hoursafter onset of...

Top Line Results of Phase III Study in Acute Ischemic Stroke (DIAS-2) Do Not Demonstrate Difference Between Desmoteplase and Placebo

PAION AG and US Partner Forest Laboratories, Inc. TodayAnnounced the Top Line Results of the DIAS-2 (Desmoteplase In AcuteIschemic Stroke) Study with the Compound Desmoteplase Aachen (Germany), May 31st, 2007 - PAION AG (Frankfurt StockExchange, Prime Standard: PA8) and its US partner ForestLaboratories, Inc. (NYSE: FRX) today announced topline results ofthe DIAS-2 (Desmoteplase In...

Ties Between Physicians and Drug Companies Still Too Strong: the Prescription Project Offers Solutions to Prevent Conflicts of Interest

BOSTON--(BUSINESS WIRE)--Apr 26, 2007 - A new study published todayin the New England Journal of Medicine ("A National Survey ofPhysician-Industry Relationships") on the extent of doctor andpharmaceutical company relationships, highlights the need forprofession-wide and public policy reforms promoted by ThePrescription Project. The article concludes that the existing,voluntary PhRMA (Pharma...

New Data from the US and Japan Support: No Established Causal Link Between Neuropsychiatric Symptoms and Treatment with Tamiflu US Databases Indicate Psychiatric Symptoms Lower in Influenza Patients Taking Tamiflu Versus Those Not Taking Tamiflu

BASEL, Switzerland, March 20, 2007 -- Clinical studies haveshown (1) similar rates of neurologic and psychiatric events inpediatric influenza patients being treated with Tamiflu compared tothose receiving no treatment for their influenza. Furthermore,recent data derived from US health insurance records (2) between1999-2006 of over 101,000 influenza patients treated with Tamifluand over 2...