beta2

An Increase in the Diagnosed Prevalent Population Will Drive Growth of Nearly $4.3 Billion in the Chronic Obstructive Pulmonary Disease Market

...patients but will remain vigilant in monitoring the safety of these drugs in their patients who receive them. The report finds that as new long-acting beta2 agonist (LABA)/inhaled corticosteroid (ICS) combinations, long-acting muscarinic antagonists (LAMAs), and LABA/LAMA products emerge from clinical deve...

Advair's Patient Share in Newly Diagnosed Asthma Patients is Declining

...ily inhaled corticosteroids (ICSs) with more favorable side-effect profiles in patients with less-severe disease prior to progressing to a long-acting beta2 agonist (LABA)/ICS combination; and physician movement towards using AstraZeneca's newly launched Symbicort as an alternative to Advair in later lines...

Emerging Combination Therapies, Including Drugs from Novartis/Schering-Plough and GlaxoSmithKline/Theravance Will Drive the COPD Drug Market to More Than $11 Billion in 2017

...eading research and advisory firms for pharmaceutical and healthcare issues, finds that the launches of emerging therapies, especially the long-acting beta2 agonist/inhaled corticosteroid combination drug class, will drive sales in the chronic obstructive pulmonary disease (COPD) drug market to more than $...

Alzheimers Disease Enzyme may Interfere With Brain Function

...that release amyloid-beta from APP also act on the beta2 subunit of neuronal sodium channels. The current s...was designed to examine how this processing of the beta2 subunit may alter neuronal function. Lead ... Kim, PhD, and colleagues first confirmed that the beta2 subunit, similar to APP, can be acted on by BACE a...

Alzheimer's-associated Enzyme Linked to Seizures

... BACE and gamma-secretase enzymes also work on the beta2 subunit of neuronal sodium channels. Sodiu...rt of the study, to test how the processing of the beta2 subunit modify neuronal function, researchers cond...om Alzheimer's patients after making sure that the beta2 subunit, similar to APP, can be acted on by BACE a...

beta2 in Biological News

Laminin builds the neuromuscular synapse

...art of the sheath that covers muscle, the laminin protein has different domains called alpha, beta, and gamma chains. Previous work had shown that the beta2 chain of laminin spurs differentiation of the nerve terminal. The team has now found evidence that the alpha chains of laminin influence post-synaptic...

beta2 in Biological Technology

Novartis/Schering-Plough's Drug Will Replace AstraZeneca's Symbicort as Decision Resources' Clinical Gold Standard by 2012 for the Treatment of Asthma

...e none of the therapies projected to launch within the next ten years are expected to offer advantages in efficacy over currently marketed long-acting beta2 agonist (LABA)/inhaled corticosteroid (ICS) combinations, Decision Resources' gold standard will be determined by incremental advantages in delivery, ...

Circassia Acquires North American and Japanese Rights to Dopexamine

...y quicker, staying in hospital for 17.5 days on average compared with 29.5 days (p = 0.001) for those who received standard therapy. Dopexamine is a beta2 adrenoceptor and dopamine receptor agonist, which is approved in Europe in indications related to heart failure. Dopexamine is not approved for use cu...