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Arthritis at Biology News

Disabling gene defuses rheumatoid arthritis in mice

Scientists studying mice have identified a gene that allows immune cells known as neutrophils to protect themselves from the inflammatory chemicals they secrete. Researchers at Washington University School of Medicine in St. Louis showed that knocking the gene out in mice prevented the development of an arthritis-like disorder by making the neutrophils victims of their own damaging secret...

Enzyme's newly discovered role may make it target for arthritis treatment

Scientists have found a new role for a previously identified enzyme that may make it a target for anti-inflammatory treatments. The finding by researchers at Washington University School of Medicine in St. Louis shows that an enzyme known as cathepsin G regulates the ability of immune cells known as neutrophils to secrete chemicals that attract other immune cells and start the local infla...

Arthritis: What Wnt wrong?

The cellular signaling protein Wnt, which is involved in embryonic development and cancer, contributes to disease progression of both rheumatoid arthritis and osteoarthritis. The article by Nakamura et al., "Expression profiles and functional analyses of Wnt-related genes in human joint disorders," appears in the July issue of The American Journal of Pathology and is accompanied by a commentary.<...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

Gene therapy for arthritis and other non-terminal, debilitating conditions and diseases is both feasible and safe, report researchers who conducted the world's first such test on the approach in patients with advanced rheumatoid arthritis. The results, published in this week's online edition of the Proceedings of the National Academy of Sciences (PNAS), indicate that introducing a new gene has th...

Synthetic Protein Eases Arthritis Symptoms in Mice

A lab-made version of a human protein alleviates symptoms of both acute and chronic arthritis in mice and could be the basis for a new arthritis drug for people, report scientists from the National Institute of Allergy and Infectious Disease (NIAID), part of the National Institutes of Health (NIH). The protein prevents the assembly of a cell surface receptor, thus blocking transmission of chemica...

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Another ray of hope for Arthritis Sufferers

Arthritis causes inflammation of a joint or joints and the surrounding tissues and affects millions of people all over the world. Anti-arthritic drugs can cause side effects and surgery can be expensive, however there is hope from a natural product liquid glucosamine and chondroitin sulfates. Some excellent results with an approach based on a combination of the two supplements have been reported...

Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis

A novel modification of a new technology born of genetic engineering, and known as naked DNA vaccination, holds the potential of overcoming autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. The vaccine is currently being successfully tested in animals. In multiple sclerosis (MS) and rheumatoid arthritis (RA), the body essentially attacks itself, caus...

Vedic vibration technology- the new cure for arthritis

One of the primary disabling ailments in the world has found a new treatment - Vedic vibration technology. A study, titled 'A double-blind randomised controlled trial of Maharishi Vedic Vibration Technology in subjects with arthritis,' revealed that scientists succeeded in achieving 100 per cent relief from painful arthritis in 36 per cent of the patients treated and at least 60 per cent...

B Vitamin protects and lowers toxicity of Arthritis Drug

Rheumatoid arthritis is an autoimmune disease that most often affects women in their 30s and 40s, especially women.The illness causes the immune system to attack the joints, which can cause pain, inflammation and joint destruction. Methotrexate is the standard drug used to treat the condition, but one third of the patients discontinue treatment early due to toxicity.//...

Tai chi helps arthritis

Researchers in Texas find that a tai chi programme improves pain and daily living activities in people with arthritis. Tai chi is an ancient Chinese system of gentle exercise which has been long held to have a wide range of health benefits. Now researchers at University in Texas report on one of the first studies of the effects of tai chi in osteoarthritis. Seventeen patients, average...

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Arthritis at Medicine Products
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Actemra (tocilizumab) Third Phase III Study Results Show Significant Improvement in Symptoms of Patients with Rheumatoid Arthritis

- Multinational Phase III Study Meets Primary Endpoint inRheumatoid Arthritis Patients Who Failed to Respond to Anti-tumorNecrosis Factor Treatments - NUTLEY, N.J., July 10, 2007 /PRNewswire/ -- Roche todayannounced that results from the Actemra Radiate (RheumAtoiDArthritIs Study in Anti-TNF FailurEs) trial successfully met itsprimary endpoint in patients with moderate to severe rheumatoi...

Anesiva Announces Phase 2 Data Showing Substantial, Long-Term Pain Reductions with Adlea(TM) (formerly 4975) in Osteoarthritis of the Knee

- Pain Reductions Observed at Eight Weeks Sustained up to 12 Weeksand Drug Remains Very Well Tolerated - SOUTH SAN FRANCISCO, Calif., July 02, 2007/PRNewswire-FirstCall/ -- Anesiva, Inc. today announced preliminarylonger-term, follow-up results from a Phase 2 study showing that a1mg treatment with Adlea(TM) (formerly 4975) in patients withmoderate-to-severe osteoarthritis of the knee prod...

Three Studies Suggest Abbott's Humira (adalimumab) May Improve Work Productivity in Patients with Rheumatoid Arthritis

One Groundbreaking Study Showed 11 Percent Fewer RA PatientsReported Job Loss When Treated With HUMIRA Combination TherapyCompared to Methotrexate Alone BARCELONA, Spain, June 15, 2007 /PRNewswire-FirstCall/ --Rheumatoid arthritis (RA) is one of the most common causes ofdisability in the Western world. New data released today show thatrheumatoid arthritis (RA) patients treated with Abbott...

Prexige Study Shows Significantly Less Impact on Blood Pressure Than Ibuprofen in Osteoarthritis Patients with Controlled Hypertension

* New data from 741-patient trial show those treated withPrexige experienced significantly smaller impact on blood pressurecompared to ibuprofen[1] * Many patients with osteoarthritis also have high bloodpressure; even small changes in blood pressure can impactcardiovascular risk[2],[3] * Prexige approved in more than 50 countries and currently underreview in US for use in o...

GlaxoSmithKline and Genmab Present Positive Phase II Results With ofatumumab in Patients With Rheumatoid Arthritis (RA)

New Data to be Presented at the European League Against Rheumatism(EULAR) Congress Demonstrates the Potential Benefit of ofatumumabin Patients With Rheumatoid Arthritis LONDON, England; PHILADELPHIA, Pennsylvania and COPENHAGEN,Denmark, June 15, 2007 /PRNewswire-FirstCall/ -- GlaxoSmithKline(GSK) and Genmab A/S (CSE: GEN) announced today positive primaryefficacy data (evaluated at 24 Week...

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Arthritis at Medicine Dictionary

Viral arthritis

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Rheumatoid Arthritis

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Psoriatic arthritis

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Osteoarthritis

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Juvenile Rheumatoid Arthritis

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