Cathepsin B increases apoptosis in fulminant hepatic failure
The traditional view is that hepatocyte necrosis is the main feature of fulminant hepatic failure, but increasing evidence implicates a dominant role for hepatocyte apoptosis
in this pathogenesis. It is not known if cathepsin B-mediated hepatocyte apoptosis
is involved in the pathogenesis of fulmi...
Sigma-Aldrich Licenses From NeuroSurvival Technologies a Leading Marker for Molecular Imaging of Apoptosis in Vivo
The marker, Apo-TRACE(TM), offers a breakthrough in advancing
apoptosis-related research in a range of fields in biology and medicine
ST. LOUIS, Feb. 26 /PRNewswire-FirstCall/ -- Sigma-Aldrich(TM) (Nasdaq:
SIAL) and NeuroSurvival Technologies Ltd. (NST) announced today that they
FASgen Diagnostic Tests Identify Ovarian Cancer Progression and Apoptosis
BALTIMORE, March 26 /PRNewswire/ -- FASgen Diagnostics, LLC is pleased
to report that results of studies using the Company's FAS-detect(TM) IHC
and FAS- detect(TM) ELISA research tests were the subject of an address to
Society of Gynecologic Oncologists annual meeting last week in Tampa,
A Combination Of Drugs Used For Anti-Angiogenesis And Apoptosis More Effective
Imantanib is a drug which prevents the growth of new blood vessels, thereby inhibiting the growth of tumour(anti-angiogenesis). //It has been discovered that using Imantanib (Glivec ) and a drug that induces cell death (apoptosis) works better. It was found that the combination was more effectiv...
Citrinin, a fungal toxin, induces apoptosis via mitochondrial pathway
The Mycotoxin citrinin (CTN) is a secondary metabolite produced by several fungal species that belong mainly to the genus Penicillium and Monascus. It is widely considered as a hazard contaminant of foods// and feeds, including corn, wheat, rice, barley and nuts, and is known to be cytotoxic and ge...
Journal of Clinical Oncology Publishes TREANDA Study Demonstrating Significant Improvement in Overall Response and Progression-Free Survival in Chronic Lymphocytic Leukemia
...own, TREANDA may act in two distinct ways to kill cancer cells. Preclinical studies suggest that TREANDA may lead to cell death by a process known as apoptosis
(programmed cell death) as well as by an alternate cell death pathway which disrupts normal cell division known as mitotic catastrophe (a non-apoptoti...
Apoptosis in Medical Technology
Apoptosis in Medical Products
VersaFluor Cuvette Fluorometer
Features:...ble filters Is the only instrument needed to detect and quantitate DNA from PCR amplification, restriction digests, and plasmid preps, to quantitate apoptosis
activity, and to assay the reporter enzymes beta-glucuronidase (GUS) and beta-galactosidase Quantitates DNA at concentrations as low as 10 ng/ml usi...
Presence of an applanation front plate
prevents cutting into the stroma.
Implication of potential better wound healing:
(more stable result).
possibly less pain.
Expected more rapid visual recovery. ...
Apoptosis in Biological News
Study by NTU professors provides important insight into apoptosis or programmed cell death
A study by Nanyang Technological University (NTU)'s Assistant Professor Li Hoi Yeung, Assistant Professor Koh Cheng Gee and their team have made an important contribution to the understanding of the process that cells go through when they die. This process known as 'apoptosis' or programmed cell d...
Novel structure proteins could play a role in apoptosis
Isoforms from Novel Structure Proteins (NSP), a new family of genes discovered by researchers in the Sbarro Institute for Cancer Research and Molecular Medicine in Temple University's College of Science and Technology, could be involved in apoptosis
or programmed cell death.
NSPs were discove...
Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance
When it comes to the deadly skin cancer melanoma, studying functional tissue rather than cell lines may better provide insight into the disease's development, according to new research from a Howard Hughes Medical Institute predoctoral fellow at Stanford University School of Medicine.
Protein that promotes cancer cell growth identified
...r of cell death proteins are missing from human tumors, allowing cancer cells to ignore the cues that keep their growth in check. Cells that can evade apoptosis
have a clear growth advantage. Because Caspase-8 is involved in programmed cell death, it would seem that reducing Caspase-8 in cancer cells would pro...
How mitochondria get their membranes bent
...rage of molecules. Cytochrome c, for example, an important signaling protein in programmed cell death (apoptosis), is stored in this compartment. When apoptosis
is triggered, the pores enlarge and cytochrome c is released into the cytosol. Thus, understanding of how the pore diameter and the shape of the inner...
Cancer: The cost of being smarter than chimps?
...estes, liver, kidneys and heart. They found distinct differences in the way apoptosis
or programmed cell death operates, suggesting that humans do not "self-destroy" cells as effectively as chimpanzees do. apoptosis
is one of the primary mechanisms by which our bodies destroy cancer cells. ...
Apoptosis in Biological Technology
Apoptosis in Biological Products
Apoptosis in Biological Definition
In biology , apoptosis
(from the Greek words apo = from and ptosis = falling, pronounced ap-a-tow'-sis  ) is one of the main types of programmed cell death (PCD). As such, it is a process of deliberate suicide by an unwanted cell in a multicellular organism . In contrast t...
...ass I histocompatibility molecules . If cytotoxic CD8 + T cells recognize them, they begin to secrete different toxins that cause the lysis or apoptosis
of the infected cell. In order to keep the cytotoxic cells from killing cells just for presenting normal proteins, they run through a test cycle (neg...
... with poor prognosis , since those tumor cells are less likely to go into apoptosis
(programmed cell death) when damaged by therapy. There are more mutations ...sarcoma , lymphoma or leukemia , have distinct properties:
unlimited growth potential (immortalitization)
self-sufficiency of ...
Cytotoxic T cell
...expand and eventually lyse . T C also release granzyme , a serine protease , that can enter target cells via the perforin-formed pore and induce apoptosis
Most T C cells have present on the cell surface the protein CD8 , which is attracted to portions of the Class I MHC molecule. This a...
..., which could lead to the specific cloning of organs for medical purposes. Another biologically important process that occurs during development is apoptosis
- cell "suicide". For this reason, many develpmental models are used to delucidate the physiology and molecular basis of this cellular process.
...e pituitary gland , which in turn is directed by the hypothalamus .
Apoptosis in Biological Dictionary
is the process of programmed cell death (PCD) that may occur in multicellular organisms. Programmed cell death involves a series of biochemical events leading to a characteristic cell morphology and death; in more... Outlines the mechanisms of cell suicide. apoptosis
.... The Iodine Source is your source for detoxified iodine. ... 9) Iodine and the Thyroid Gland . 10) Iodine Functions in the Body. 11) Iodine and apoptosis
... What is your thyroid gland ? ... The thyroid gland is located in the middle of the lower neck, below the larynx ... "masses" in their ...
...strated their ... tigate the changes in the Schwann cells found in Golgi tendon ... apoptotic death of these Schwann cells and that this apoptosis
... The Schwann cells are also present, and they closely cover every branch of the neuron. ... This work suggests that signal comes from the ...
...e ... The Ty5 retrotransposon is used as a genetic model to study the architecture and ... Human LINE-1 retrotransposon induces DNA damage and apoptosis
in cancer cells ... Jr, Boeke JD: Human L1 retrotransposon encodes a conserved endonuclease required ... inferred from 33 non-LTR retrotr...
...a biomarkers for Alzheimer's disease" ... Proteome Resources provides enzymes, nucleases and protein expression services to ubiquitin and apoptosis
research scientists in academic, government, ... Proteome Software would like to hear what you have to say about Proteomics, and ... To get the ...
...toplasm and nucleus of all eukaryotic cells that is the site The scientific resource for elucidating the Ubiquitin / Proteasome Pathway. ... apoptosis
meets proteasome , an invaluable therapeutic target of anticancer drugs. ... Ubiquitin and Proteasome Proteasome , signalosome, & TPPII ...