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Elusive HIV shape change revealed; Key clue to how virus infects cells

Structural biologists at Children's Hospital Boston and Harvard Medical School have shown how a key part of the human immunodeficiency virus (HIV) changes shape, triggering other changes that allow the AIDS virus to enter and infect cells. Their findings, published in the Feb. 24 issue of the journal Nature, offer clues that will help guide vaccine and treatment approaches. Researchers led...

Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine

Scientists at St. Jude Children's ResearchHospital have discovered that the shape of a protein on the surface ofpneumonia bacteria helps these germs invade the human bloodstream. Thisfinding, published Dec. 16 online by the EMBO Journal, could helpscientists develop a vaccine that is significantly more effective atprotecting children against the disease. The St. Jude researchersdetermined t...

Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site

The National Library of Medicine, a part of the National Institutes of Health, is proud to present an extensive selection from the papers of one of the twentieth century’s greatest scientists, Francis Crick, on its Profiles in Science Web site. Don't miss Crick's This la...

The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures

The Protein Structure Initiative (PSI), a national program aimed at determining the three-dimensional shapes of a wide range of proteins, has now determined more than 1,000 different structures. These structures will shed light on how proteins function in many life processes and could lead to targets for the development of new medicines. The PSI is a 10-year, approximately $600 million pr...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

New research on prions, the infectious proteins behind "mad cow" disease and Creutzfeld-Jakob disease in humans, suggests that the ability of prions in one species to infect other species depends on the shape of the toxic threadlike fibers produced by the prion. Two studies on the topic appear in the 8 April issue of the journal Cell. Although research suggests that prions from one specie...

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CORNING SPATULA, TAPERED BLADE/SPOON, STERILE from Sigma-Aldrich

Description:Corning single use spatulas have been designed to save time and provide contamination-free samples. They are for those interested in eliminating the recycling and resterilizing necessary with reusable spatulas. Each spatula is individually packaged, RNase/DNase free, non-pyrogenic and antistatic. Linkage: This CLS number is a new product number, created to easily match Cornings product number....
Company:Sigma-Aldrich

CORNING CELL SCRAPER, SMALL ,STERILE from Sigma-Aldrich

Description:Useful for the mechanical harvesting of cells • Blade design minimizes cell damage and ensures even contact with the growth surface • Designed for use in 25 and 75cm flasks • Individually wrapped • Sterilized by gamma radiation and certified nonpyrogenic Linkage: This CLS number is a new product number, created to easily match Cornings product number. If showing no availabi...
Company:Sigma-Aldrich

CORNING CELL SCRAPER, LARGE, STERILE from Sigma-Aldrich

Description:Useful for the mechanical harvesting of cells • Blade design minimizes cell damage and ensures even contact with the growth surface • Designed for use in 25 and 75cm flasks • Individually wrapped • Sterilized by gamma radiation and certified nonpyrogenic Linkage: This CLS number is a new product number, created to easily match Cornings product number. If showing no availabi...
Company:Sigma-Aldrich

RapidVUE® Particle Shape and Size Analyzer from Beckman Coulter

Description:The RapidVUE is a particle shape and size analyzer offering a wide dynamic range. It has been designed with the utmost simplicity in mind. It is comprised of a chemically compatible sample delivery module and an optical bench. The system is completely computer controlled. The modular design allows for easy upgrade for different applications such as dry or where smaller volumes are required. Simpl...
Company:Beckman Coulter

Telomerase Gel-based assay Assay Kit, TRAPeze from CHEMICON

Description:...
Company:CHEMICON

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Reducing brightness to make a better paper

The federal government annually buys s...

New Cape Clear president is UW business alum

Joe Voica, whose MBA and undergraduate degree were minted at the University of Wisconsin, has been named president of Cape Clear Software's North American operations, the company said on Wednesday. He has 20 years of management experience. Cape Clear, headquartered in Massachusetts, provides "enterprise service bus" technology to a list of clients that includes the State of Wisconsin Dep...

Biologist who cloned Dolly the sheep believes therapeutic cloning will gain acceptance

Wilmut, a biologist with the <a href="http://www.re...

Early Stage, Step 9: Raising capital in the securities landscape

- The idea is developed. Lawyers and accountants are on board. The intellectual property has been protected. The entity is formed. The name...

Emergence of Internet video is changing the regulatory landscape

This homegrown series may not be Stars...

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Fitness landscape

success. It is assumed...

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Stapes

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Chaperone Proteins

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Chaperone protein

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Adaptive landscape

for each combination plotted in the thir...

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Drink grape juice for health

Actually, purple grape juice provides far greater antioxidant effects than orange juice. according to a study published in the journal of medicinal food. The study states that, people who are looking to promote their cardiovascular health through increased antioxidant consumption might prefer a glass of purple grape juice in the morning to orange juice," says Joe A. Vinson, professor...

Cipro Has Cheaper Cousins to Treat Anthrax

Cipro, Cipro, Cipro. That's been the mantra of the media as dozens of people exposed to anthrax -- and thousands who weren't -- clamor for the potent antibiotic. But if the supply dwindles, doctors say other cheaper and widely available medications can be used, including a previous generation's wonder drug: penicillin. Although alternatives exist, Cipro is the latest and greatest, so it t...

Shapely sperm-a valuable indicator of fertility

According to a study, shapely sperm is the best indicator of a man's fertility, that rewrites the standards for analyzing semen samples. According to Dr. Dav Guzhik, chairman of obstetrics and gynecology at the University of Cleavland, every treatment for infertility depends upon first establishing what's normal and abnormal. The World Health Organization's widely used standards to class...

Body can reshape heart damage

Using the male chromosome as a marker, researchers studying eight cross-gender heart transplants from New York Medical College have discovered that the body can actively reshape the heart after injury.// The research explodes the long-standing belief that the heart cannot repair itself and the finding has implications for heart disease treatment. The realization that the body works...

Grapes, Melons Implicated in Outbreaks

According to researchers , there is a new study on seedless green grapes which caused a salmonella outbreak that sickened 30 people across six Western states last summer and fall. Researchers were surprised to find that the outbreak of Salmonella serotype senftenberg// most often found in meats and poultry was outwardly spread to people through grapes. Dr.Alicia, at the International C...

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Disposable Bipolar Pencil - 23 Gauge Tapered Tip

Description:18 gauge tapered fine tip. Lightweight design offers precise hemostasis. Pencil design minimizes tissue trauma and induced astigmatism. Knurled handle provides a sure grip and better manipulation....
Company:Bausch & Lomb Storz

Paparella Incudostapedial Joint Knife

Description:0.5 mm wide x 1.5 mm long. Angled 20 degrees. Octagonal handle....
Company:Bausch & Lomb Storz

Guilford-Wright Incudostapedial Knife

Description:1.5 mm long blade. Square handle....
Company:Bausch & Lomb Storz

House Incudostapedial Joint Knife

Description:0.75 mm diameter blade. Angled 60 degrees. Round handle. Designated most popular model or size....
Company:Bausch & Lomb Storz

Wet-Field Hemostatic Eraser Bipolar Tip (20-23 gauge Tapered/Blunt Point, Curved 150)

Description:...
Company:Medtronic Xomed, Inc.

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Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse

In keeping with the recent proliferation of rapid, easy-to-use diagnostic tests, many assays and collection products have entered the marketplace to help clinicians assess dosage appropriateness of therapeutic drugs and to screen for the presence of drugs of abuse. Some of these products require laboratory support while many simple test kits are suitable for point of care use by medical profe...

Cell Therapeutics, Inc. Management to Discuss Today's Announcement of Interim Pixantrone Study Results

SEATTLE, July 11, 2007 /PRNewswire-FirstCall/ -- On Wednesday,July 11, 2007, at 1:30 p.m. Pacific/4:30 p.m. Eastern/10:30 p.m.Central European Time members of Cell Therapeutics, Inc.'s (CTI)management team will host a conference call to discuss today'sannouncement of the interim results of its phase II/III RAPID trialcomparing CHOP-R to CPOP-R, in which pixantrone is substituted fordoxor...

Halozyme Therapeutics' Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society

- Co-Injection of rHuPH20 with Humira Estimated to Increase theMaximal Steady State Subcutaneous Bioavailability from 64% to 100%- SAN DIEGO, July 09, 2007 /PRNewswire-FirstCall/ -- HalozymeTherapeutics, Inc. , a biopharmaceutical company developing andcommercializing recombinant human enzymes, today announced thatfinal results of the Enhanze(TM) Technology clinical trialdemonstrating im...

CV Therapeutics Identifies Potential Anti-Diabetic Mechanism of Action for Ranexa

-- New Preclinical Information May Correlate with Clinical HbA1cReductions Observed in Phase 3 CARISA and MERLIN TIMI-36 ClinicalTrials -- PALO ALTO, Calif., July 9, 2007 /PRNewswire-FirstCall/ -- CVTherapeutics, Inc. announced today that researchers have completedpreliminary preclinical studies showing that ranolazine increasedglucose stimulated insulin secretion in pancreatic beta cells...

GTC Biotherapeutics to Webcast Corporate Presentation at the C.E. Unterberg, Towbin Emerging Growth Life Opportunities Conference

FRAMINGHAM, Mass.--(BUSINESS WIRE)--Jul 5, 2007 - GTCBiotherapeutics, Inc. ("GTC", Nasdaq: GTCB) announced today thatGeoffrey Cox, Ph.D., GTC's Chairman and CEO, is scheduled topresent on Wednesday, July 11, 2007 at 9:00 a.m. during the C.E.Unterberg, Towbin Emerging Growth Life Opportunities Conference.The conference is being held at the Mandarin Oriental Hotel, NewYork, New York from July...

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Therapeutic gene modulation

in that gene modulation seeks to alter the expressi...

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Tapeworm

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Tapeworm Infection

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Diaper rash

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