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FDA Warns About Antipsychotic Drugs and Elderly

The Food and Drug Administration (FDA) today issued a public health advisory to alert health care providers, patients, and patient caregivers to new safety information concerning an unapproved (i.e., "off-label") use of certain drugs called "atypical antipsychotic drugs." These drugs are approved for the treatment of schizophrenia and mania, but clinical studies of these drugs to treat behavioral...

Studies look at how genes affect antipsychotic drug response

Researchers at the University of Illinois at Chicago College of Pharmacy are attempting to discover how genes determine how well an antipsychotic medication works in adults and children and the side effects it will cause. Jeffrey Bishop, assista...
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Femtogram Sensitivity of the Antipsychotic Drugs Raclopride and Ritanserin Using a Varian 1200L LC/MS/MS

Varian, Inc. These two compounds were used to demonstrate low-level sensitivity of...
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Antipsychotic Drug Linked to Pulmonary Embolism

A case study published in the British Medical Journal suggests a common antipsychotic drug might have caused a pulmonary embolism in an otherwise healthy young man.// A pulmonary embolism results when a blood clot that developed elsewhere in the body travels to the lung. The result can be deadly. Antipsychotic drugs have been linked to an increased risk of blood clots in the past. Speci...

FDA warnings against use of antipsychotic drugs for elderly

The Food and Drug Administration (FDA) of US had warned the public and medical professionals against use of //certain drugs broadly called as atypical antipsychotic drugs on elderly patients with dementia. The drugs, aripiprazole, olanzapine, quetiapine, risperidone, clozapine and ziprasidone, are approved for the clinical treatment of schizophrenia and mania. Use of these drugs to tre...

A word of caution issued by the FDA for those using antipsychotic drugs for dementia

The US Food and Drug Administration has issued a public notice regarding the fatal adverse events associated with demented patients// treated with atypical antipsychotic drugs. The notice was issued based on Seventeen controlled studies of elderly demented patients who were treated with the drugs. It was found that they were 1.6 to 1.7 times more likely to die than patients given placebo...

New Antipsychotic Medications have Little Advantage Over Older Drugs

Among patients with schizophrenia whose medication is changed because of ineffectiveness or harmful side effects, second-generation// antipsychotic drugs do not appear to offer significant benefits compared to first-generation antipsychotic drugs, according to a report in the October issue of Archives of General Psychiatry, one of the JAMA/Archives journals. The findings run contrary to...

Antipsychotics – not effective in treating Alzheimer'

According to a major recent countrywide study, antipsychotic drugs that are prescribed for delusions, agitation or aggression have no effect in treating Alzheimer's disease as most of the patients discontinue the drugs due to the side effects. // This study was conducted by Lon Schneider, professor of psychiatry, neurology and gerontology and his team at the Keck School of Medicine of...

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Antipsychotic Iloperidone Results Show Favorable Akathisia Profile

SAN DIEGO, May 22, 2007 /PRNewswire-FirstCall/ -- According tostudy results presented today at the 2007 American PsychiatricAssociation annual meeting, iloperidone, an investigationalatypical antipsychotic, was shown to have a favorable akathisiaprofile. Akathisia -- a debilitating sensation of restlessness thatmanifests as an inability to sit still -- is a frequent side effectof antipsy...

New Data Show Early Non-Response to Antipsychotic Treatment May Be Strong Predictor of Subsequent Non-Response for People with Schizophrenia

Findings indicate early non-responders unlikely to subsequentlyrespond, have substantially more treatment costs, and may benefitfrom earlier change in treatment strategy COLORADO SPRINGS, Colo., April 03, 2007 /PRNewswire-FirstCall/-- New data presented at the 2007 International Congress onSchizophrenia Research (ICOSR) suggest that antipsychotic drugresponse be assessed earlier than is p...
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