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antiobesity in Biological News

Weight control protein may yield antiobesity drugs

A weight control protein with a key role in the brain's ability to monitor body fat content may yield new approaches for treating obesity and type 2 diabetes, according to a new report in the August issue of Cell Metabolism. The findings in mice further suggest that particular variants of the prote...

In obesity, brain becomes 'unaware' of fat

...in critical brain regions is a cause of obesity induced by diet, the researchers concluded. The results also “strongly validate?SOCS-3 as a target for antiobesity drug development. ...

New player in commitment to life as a fat cell

...bolism, published by Cell Press. Drugs that block some activities of the enzyme, known as xanthine oxidoreductase (XOR), might therefore offer a novel antiobesity therapy designed to fight fat before it even forms, the researchers said. Known for its role in producing the metabolic byproduct uric acid, XOR had...

Machinery of the 'marijuana munchies'

... signaling regulates the excitability of neurons on appetite-related circuits." They also wrote that "the cellular mechanisms of recently developed antiobesity drugs, such as rimonabant, may include decreased endocannabinoid signaling and hence decreased excitability of LH circuits related to appetite, even i...
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