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androstane in Medical News

JCI online early table of contents: Aug. 1, 2008

... had indicated a role for both PXR and CAR. TITLE: A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response AUTHOR CONTACT: Nico Scheer TaconicArtemis, Cologne, Germany. Phone: 49-221-9645343; Fax: 49-221-9645321; E-mail: n.s...

Attenuation of NASH by stimulation of free fatty acid metabolism

... the population. The article describes how administration of a constitutive androstane receptor (CAR) agonist (TCPOBOP) can induce genes involved in fatty acid mi...e metabolism of various biologic compounds. In particular, the constitutive androstane receptor (CAR), which is highly expressed in the liver, is a biosensor for ...
androstane in other areas

androstane: Definition from Answers.com

The constitutive androstane receptor (CAR), also known as NR1I3, is a nuclear hormone receptor with activity similar to that seen in other steroid receptors such as estrogen or progesterone but more similar in form to PPAR, LXR and RXR. CAR functions differently from...

androstane - definition of androstane in the Medical dictionary - by ...

What is androstane? Meaning of androstane medical term. What does androstane mean? ... androstane /an·dro·stane/ (an'dro-stān) the hydrocarbon nucleus, C19H32, from ...

androstane - Definition from the Merriam-Webster Online Dictionary

Definition of androstane from the Merriam-Webster Online Dictionary with audio pronunciations, thesaurus, Word of the Day, and word games.

Pharmacological Profile of the Novel Inotropic Agent (E,Z)-3-((2 ...

... (E,Z)-3-((2-aminoethoxy)imino)androstane-6,17-dione hydrochloride (PST2744) was ... of Na+,K+-ATPase: 17-substituted seco-D-5-androstane as cassaine analogs. ...

Mouse Liver Effects of Cyproconazole, a Triazole Fungicide: Role of the ...

The constitutive androstane receptor (CAR) has been shown to play a significant ... androstane receptor regulate overlapping but distinct sets of genes involved in ...

A Concentration Addition Model for the Activation of the Constitutive ...

The constitutive androstane receptor (CAR) responds to endobiotics and ... Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. ...
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