analyses

Expression Project for Oncology (expO) completes first phase of standardized gene expression analyses

The International Genomics Consortium’s (IGC) Expression Project for Oncology (expO) has released clinically annotated gene expression profiles for 60 tumor specimens, completing the initial phase of the nation’s first and eventually largest public database dedicated to standardized gene expression data. The clinically annotated dataset is available in the public domain through the National Cente...

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Critical factors for successful microarray and real-time PCR analyses

QIAGEN GmbH, Hilden, Germany Gene expression profiling at the RNA level has been significantly facilitated by microarray analysis and quantitative real-time RT-PCR. Microarray analysis offers the advantage of profiling expression levels of hundreds or thousands...

Isolation to Functional Analyses

While the microRNA (miRNA) field is rapidly expanding, these small, non-poly(A) tailed molecules still pose challenges for research. Most RNA analysis techniques have been optimized for longer molecules, not small 21-23 nt RNAs. Their small size precludes standard RT-PCR analy...

Use of On-line Size Exclusion Chromatography (SEC) for Sample Clean-up in LC/MS Analyses

Use of LC/MS has experienced a dramatic increase in applications throughout the drug discovery and development process, from high-throughput screening...

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Using Body Mass Index Skews Analyses on Obesity Rates

When researchers use percent of body fat data to assess obesity rather than body mass index (BMI), the huge gap in obesity rates between African-American //and white women, for example, is cut in half, and white men are found to have a much higher risk of obesity than African-American men. While the medical literature has long showed that percent of body fat is a more accurate measure...

A New Study Analyses Benefits Of Statin Drug

A new Canadian-led review on statin drug concluded that the drug has the potential to reduce the risk of heart attack and stroke in people with no history of cardiovascular// diseases. But the reduce in the risk of death cannot be assured by this cholesterol-lowering drug. Statins, the best selling and widely used among the family of drugs, help the patients in lowering levels of arter...

UAE Analyses HIV Policies to Plan National Strategy

The United Arab Emirates (UAE) is analysing its HIV/AIDS policies to develop a five-year national strategy concerning the killer disease, Gulf News// reported Thursday. Officials from governmental agencies as well as international organisations, including the Red Crescent Authority, UNAIDS and UNDP, discussed the HIV/AIDS situation in the country at a workshop. The worksho...

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New Study Analyses Confirm Once-Daily Seroquel XR Extended-Release Tablets as Effective Treatment for Schizophrenia

--Study Used To Support FDA Approval of SEROQUEL XR-- WILMINGTON, Del., May 22, 2007 /PRNewswire-FirstCall/ --AstraZeneca today announced that two analyses from a large-scalestudy that investigated the efficacy of SEROQUEL XR(TM) (quetiapinefumarate) Extended-Release Tablets, a once-daily medicine for thetreatment of schizophrenia in adult patients, were presented todayat the annual meeti...

New Long-Term Data Analyses for Bifeprunox Show Favorable Effects Versus Placebo in Stabilized Patients with Schizophrenia

Six-Month Data Show Bifeprunox Maintained StabilitySignificantly Longer than Placebo and had a Favorable Weight andLipid Profile Comparable with Placebo MARIETTA, Ga. and COLLEGEVILLE, Pa., May 22, 2007 - SolvayPharmaceuticals, Inc., Wyeth Pharmaceuticals, a division of Wyeth(NYSE:WYE), and Lundbeck A/S presented clinical study results onbifeprunox, an investigational treatment for...

Medivation Announces Presentation of New Subset Analyses From Dimebon Phase 2 Alzheimer's Disease Trial at American Academy of Neurology Annual Meeting

Company Conference Call Scheduled for Friday, May 4, at 9:00 a.m.Eastern Time to Discuss Data SAN FRANCISCO, May 03, 2007 /PRNewswire-FirstCall/ --Medivation, Inc. today announced that new data from the mild andmoderate subgroups of Alzheimer's disease patients in the Company'ssix-month Phase 2 efficacy study of Dimebon showed that bothsubgroups were improved compared with placebo-treated...

Data Analyses Outline Efficacy and Safety of Mircera for the Treatment of Renal Anemia Associated With Chronic Kidney Disease

ORLANDO, Fla. and NUTLEY, N.J., April 12, 2007/PRNewswire-FirstCall/ -- Data analyses from the largest initialregistration clinical trial program ever undertaken in the renalanemia arena provide efficacy and safety information on theinvestigational anemia therapy MIRCERA(TM) for the treatment ofrenal anemia associated with chronic kidney disease (CKD) inpatients on dialysis and not on di...

Safety Analyses of Clinical Data for Bifeprunox in Patients with Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar to Placebo

COLLEGEVILLE, Pa., March 30, 2007 /PRNewswire-FirstCall/ --Wyeth Pharmaceuticals, a division of Wyeth , SolvayPharmaceuticals, Inc. and Lundbeck A/S presented clinical studyresults on bifeprunox at an international medical congress thisweek. Safety analyses suggest bifeprunox, an investigationaltreatment for adult patients diagnosed with schizophrenia, wasassociated with a favorable weig...

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