Genetic Breakthrough Spells Hope for Lung Fibrosis Patients
... disease. The researchers found no evidence that infection or inflammation was the cause of accelerated IPF. They did find signs that the cells of the alveolar
epithelium, the tissue that covers the surface of the lung's air sacs, were rapidly dying.
"That could mean that drugs that are used to protect the...
Over half of people with rheumatoid arthritis have periodontitis
...o modulate the inflammatory process in the periodontium (the tissues investing and supporting the teeth, including the cementum, periodontal ligament, alveolar
bone, and gingival / gums).
Dr Codrina Ancuta of the Grigore T Popa University of Medicine and Pharmacy, Rehabilitation Hospital, Iasi, Romania, who...
Targeting the more lethal form of the cancer rhabdomyosarcoma
...domyosarcoma (RMS) is an aggressive muscle cancer that mostly affects children. The most common forms of RMS are embryonal rhabdomyosarcoma (ERMS) and alveolar
rhabdomyosarcoma (ARMS). Although ARMS is less common than ERMS, it is associated with a much higher rate of mortality. A therapy tailored to the ARMS...
U.S. Department of Defense Exercises $2.0 Million Option to Fund Cethromycin Development
...n at 75 mg/kg over 21 days offered 100% protection from tularemia infection. USAMRIID concluded that cethromycin's preferential accumulation in the alveolar
cells of the lungs, combined with the oral bioavailability and once a day dosing make cethromycin an attractive candidate for use in tularemia therapy...
Coalition for Pulmonary Fibrosis and American Thoracic Society Announce Recipients of 2009-10 Research Awards
... "Contribution of Epithelial Mesenchymal Transition (EMT) to Pulmonary Fibrosis." EMT is induced by transforming growth factor beta signaling in the alveolar
epithelium and plays a pivotal role in determining whether the response to tissue injury leads to normal repair or lung fibrosis. Dr. Tanjore's study...
Frost & Sullivan Recognizes Neotropix's Approach to the Treatment of Small Cell Lung Cancer and Neuroendocrine Cancers
...cancer and carcinoid cancer. It can also potentially treat children with neuroblastoma, Wilms' tumor, Retinoblastoma, Ewing's sarcoma, Rhabdoid tumor, alveolar
rhabdomyosarcoma, and glioblastoma.
This virus, through a receptor-mediated process, selectively targets neuroendocrine tumor cells that express ...
Study sheds light on deadly lung disease
...de insight into extreme vulnerability to fibrosis associated with injury to alveolar
epithelial cells (AECs)cells that line the tiny air sacs in the lungsaggrav...eomycin was found independent of inflammation, but associated with impaired alveolar
epithelial repair. ...
Kristin Chenoweth to Perform Benefit Concert for 3 Angels Memorial Fund titled, 'Kristin Chenoweth, This One's Personal: A Concert to Stop ACD'
seven weeks old to a disease called ACD. This is the third child Craig has
lost to the disease, making it nothing short of a genetic mystery.
Capillary Dysplasia (ACD) is a thought to be rare genetic lung
disease that has killed every baby known to be diagnosed with it. Prior to
Reconstructing mandibular defects with bioengineered tooth and bone
... formation of not only the tooth crowns but also tooth root and surrounding alveolar
bone was observed. However, since the omentum offers an environment quite d...econstructions in humans. This model is currently being modified to improve alveolar
bone formation, regenerated dental tissue orientation, tooth root developme...
HPV, periodontitis work in tandem to increase risk of tongue cancer
...te for whom data was available on both periodontitis and tumor HPV status. Cumulative history of periodontitis was determined by assessing the loss of alveolar
bone, the bones that underlie and support the teeth, via X-ray.
Tumor status was identified from paraffin-embedded tumor samples analyzed by polymer...
alveolar in Medical Technology
alveolar in Medical Products
Description:... Enzyme immunoassay for the quantitative determination of IgG autoantibodies against type IV collagen of glomerular or alveolar
basement membrane (GBM) in serum and plasma....
Company:DLD Diagnostika GmbH
Irri-Cath® Suction Systems
Description:... Irri-Cath® catheters help decrease the need for frequent suctioning and provide an alternative to fiber-optic bronchoscope for bronchial alveolar
lavage as a diagnostic aid in opportunistic infections.
All Portex® Irri-Cath® suction systems are latex-free.
The Irri-Cath® suct...
alveolar in Medical Definition
High Frequency Ventilation
...ion, atelectatic regions will inflate, however the alveoli will be unstable and will collapse during the expiratory phase of the breath. This repeated alveolar
collapse and expansion (RACE) will cause VILI. By opening the lung and keeping the lung open RACE (and VILI) is reduced.
Types of High Freque...
... corneal dystrophy
Cutaneous lichen amyloidosis
Corneal lactoferrin amyloidosis
Surfactant protein C (SP-C)
Critical illness myopathy (CIM)
Hyperproteolytic state of myosin ubiquitination
alveolar in Medical Dictionary
...nia in... Pneumonia is an inflammatory illness of the lung. Frequently, it is described as lung parenchyma/alveolar inflammation and abnormal alveolar
filling with fluid . Pneumonia is a lung infection that can be caused by different types of germs, ... Wheezing may be more common in viral ...
..."http://en.wikipedia.org /wiki/ Surfactant " ... Pulmonary surfactant is a surface-active lipoprotein complex formed by type II alveolar
cells. The proteins and lipids that surfactant comprises have both a hydrophilic region and a hydrophobic region. By adsorbing to the... A surf...
...ncerous) tumors that can develop from fat, muscle, nerve, ... types of soft tissue tumors is important. ... Soft Tissue Sarcoma Key Terms: alveolar
rhabdomyosarcoma , Brachytherapy , Cytogenetics , Dermatofibrosarcoma protuberans , Embryonal rhabdomyosarcoma Many soft tissue sarcomas are...
...ers resources on the cancer and its treatment. Rhabdomyosarcoma and alveolar
rhabdomyosarcoma treatment, for a rare soft-tissue cancer at Mayo Clini... rhabdomyosarcoma is increased in children with the genetic disorder ... alveolar
rhabdomyosarcoma cells usually have a rearrangement of chromosomes 2 .....
... Respiratory alkalosis results from increased alveolar
respiration leading to decreased plasma carbon dioxide concentration. This leads to decreased hydrogen ion and freely ionized blood calcium ...
...e respiratory acidosis can be life threatening when a sudden and sharp ... Overview: Respiratory acidosis is a clinical disturbance due to alveolar
hypoventilation. ... Acute respiratory acidosis is present when an abrupt failure of ... Respiratory acidosis is a condition in which a bu...
...... Pulmonary Edema . WHAT YOU SHOULD KNOW ... INTRODUCTION Neurogenic pulmonary edema (NPE) is an increase in pulmonary interstitial and alveolar
fluid due to, and usually developing rapidly after, acute central ... Pulmonary edema . Symptoms: Heart Failure. in heart failure. see also...
... disease (ILD), also known as diffuse parenchymal lung disease (DPLD), refers to a group of lung diseases affecting the interstitium . It concerns alveolar
epithelium, pulmonary capillary endothelium,... Idiopathic pulmonary fibrosis (IPF), formerly known as cryptogenic fibrosing alveolitis, is a ...
... Pneumonia is an inflammatory illness of the lung. Frequently, it is described as lung parenchyma/alveolar inflammation and abnormal alveolar
filling with fluid . Comprehensive overview of the respiratory disease, symptoms, causes, diagnosis, and treatment. Explains about the infe...
...atory diseases affecting the periodontium — that is, the tissues that surround and support the teeth. Periodontitis involves progressive loss of the alveolar
bone around the teeth,... Periodontitis — Comprehensive overview covers symptoms, causes, treatment, prevention of this ... Periodontitis ca...
alveolar in Biological News
Heat-shock protein vaccine reduces alveolar bone loss
Heat-shock protein (HSP) can be utilized as a vaccine to cross-protect against multiple pathogenic species. Investigators from Pusan National University (South Korea) today presented the findings of a study they performed to evaluate the bacterium Porphyromonas gingivalis heat-shock protein (HSP) 6...
Pitt team first to profile genes in acutely ill idiopathic pulmonary fibrosis patients
... was no evidence that infection or inflammation was the cause of disease acceleration, he noted. Instead, there were indications that the cells of the alveolar
epithelium, which is the tissue that covers the surface of the air sacs, were rapidly dying.
"That could mean that drugs that are used to protect ...
Harvard scientists solve mystery about why HIV patients are more susceptible to TB infection
...ecimens from the HIV-positive patients and found increased levels of a molecule called IL-10, which elevated the amount of a protein called "BCL-3" in alveolar
macrophages and that reduced their ability to ward off TB infection.
"HIV and TB represent two of the most significant health challenges in human...
Dual role in breast tissue for a protein involved in leukemia
...trogen receptor was over-expressed, Stat5a collaborated with it to promote growth of a type of precancerous lesion of the breast termed a hyperplastic alveolar
"Our studies in in vivo mouse models illustrate a dual role for the Stat5a protein in breast tissue. While it can contribute to the growth o...
Gene therapy appears safe to regenerate gum tissue
...stages for these studies will commence in the next year.
The paper, called "Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered to alveolar
Bone Defects Exhibits Safety and Biodistribution Profiles Favorable for Clinical Use," is partially available online. It's scheduled to appear in the ...
Study: Fluid buildup in lungs is part of the damage done by the flu
...only half as effective as fluid clearance from the lungs of uninfected mice.
Lung infections have been known to cause problems with what is called alveolar
fluid clearance, but the effects of the flu on the lungs had not been tested before, Davis said. The alveoli are air spaces deep inside the lungs wher...
Shades of 1918? New study compares avian flu with a notorious killer from the past
...unch to the host's ability to recover from the infectious siege. The researchers observed that within 24 hours, H5N1 had caused severe bronchiolar and alveolar
lesions in lung tissue.
H5N1's penchant for infecting type II rather than type I pneumocytes is due to the receptor preference found in avian viru...
Inherited genetic cause, possible treatment found for complex lung disorder
...enetic mutation that causes an inherited form of the lung disease Pulmonary alveolar
Reporting their results in the Nov. 24 Journal of Ex... where patients do not exhibit obvious symptoms, according to the Pulmonary alveolar
Proteinosis Foundation. The researchers in this report were intrigued by th...
Immunotherapy in high-risk pediatric sarcomas shows promising response
... also found that survival in these patients was at the higher end of what is generally seen with recurrent and/or metastatic Ewing's sarcoma (ESFT) or alveolar
rhabdomyosarcoma (AR) the two sarcomas tested in this single arm study. The 22 enrolled patients who did not receive immunotherapy had a 31 percent f...
Translational research patented first experimental treatment against idiopathic pulmonary fibrosis
...s to type 1 pneumocytes in alveoli, cells recovering the inner walls of the alveolar
cavity. Occupying the same spaces, there are also type II pneumocytes, precursor cells that repair the damaged alveolar
tissue. When idiopathic pulmonary fibrosis appears, this regeneration proce...
alveolar in Biological Technology
Cardium Announces New Orthobiologics Product Initiative Extending Gene Activated Matrix Technology to Deliver Bone Growth Factors
...l Transduction, (Lin, et al., J Periodont Res , 2008; 43: 440-449); and (4) Adenovirus Encoding Human Platelet-Derived Growth Factor-B Delivered to alveolar
Bone Defects Exhibits Safety and Biodistribution Profiles Favorable for Clinical Use, (Chang, et al., Human Gene Therapy , 2009 May; 20: 486-496). T...
Depth of MedImmune's Respiratory Disease Research Program Highlighted at Annual Meeting of the American Thoracic Society
...:15 p.m., Metro Toronto Convention Centre, Area B.
-- Monocytes and Macrophages in Inflammation, Immunity and Injury (Poster Session: Role for alveolar
Macrophages in Limiting Primary RSV Immunopathology, publication page A623) - Tuesday, May 20 from 8:15 a.m. - 4:15 p.m., Metro Toronto Conven...
Enzyme Immunoassay for Studying Intracellular Levels of cAMP
...tion to Jurkat cells, AC toxin has also been
shown to elevate cAMP in monocyte macrophages, 10 polymorphonuclear
leukocytes and alveolar
macrophages, 11 natural killer cells 12
and HL-60 promyelocytic leukemia cells. 13
The EIA cAMP Kit is a nonradioact...
alveolar in Biological Products
Goat Anti-PAX3 Polyclonal Antibody, Unconjugated from GeneTex
Description:...ociated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar
rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar
rhabdomyosarcoma. Alternative splicing results in transcripts encoding isof...
alveolar in Biological Dictionary
...ds do not have a maxilla in the strict... The alveolar
process is the thickened ridge of bone that contai...nes that bear teeth. It is also referred to as the alveolar
bone. In humans, the tooth-bearing bones are the maxilla and the mandible. The mineral content of alveolar
bone is mostly... Lifestyle, fitness & he...
...of a lobe. ... ... lobule from Webster's New World College Dictionary. Meaning of lobule . ... Branches within the primary lobule give rise to alveolar
ducts, ... lobule usage ... Within each lobule , hepatocytes are arranged into hepatic cords separated by ... The Liver Lobule , from Blue Hi...
...on of Interstitial cells in the Online Dictionary. Meaning of Interstitial cells . ... In the lungs, scattered interstitial cells and a few alveolar
... Definition of interstitial cell in the Online Dictionary. Meaning of interstitial cell . ... Interstitial Cell Stimulating Hormone. ...
... : Cell Sample Size Colors Shape Alive or Dead. Cork ... Cork is a natural product. Each cell contains an air-like gas the cell walls ... alveolar
cell structure but from openings – pores – in the cork tissue, called ... ...
... bronchi and bronchioles with secondary infection, usually involving ... ... in the membranous and respiratory bronchioles and rupture of the alveolar
... At least 50 bronchioles were examined per animal, and the injury score (IS) was ... ...
...y? Breathing! ... There are about 600 million alveoli in your lungs and if ... Now that's a load of alveoli ! ... Along the distal end of an alveolar
duct, the alveoli are arranged into grape-like clusters. ... routes to and from the alveoli if an obstruction occurs. ... The alveoli are sma...