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It's not all genetic: Common epigenetic problem doubles cancer risk in mice

In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there. Roughly 10 percent of people have this double protein dose as well. In...

Researchers find how protein allows insects to detect and respond to pheromones

University of Washington TechTransferrecently licensed software that will give scientists a huge advantagein the fight against disease.The software, known as Rosetta, predicts how proteins fold, informationthat is highly valuable to biological and biomedical researchers.UW Tech Transfer's Digital Ventures licensed Rosetta software withoutcharge to the Institute for Systems Biology (ISB), a...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

In a new study, researchers present a “cautionary tale?about what may go wrong when using the fledgling science of proteomics to devise a diagnostic test for cancer. In the February 16 issue of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an experimental test intended to identify early ovarian cancer from a...

Inflammatory molecules released by pollen trigger allergies

How do pollen particles provoke allergic reactions? A new study in the February 21 issue of The Journal of Experimental Medicine puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immune cells and cause them to launch a typical allergy-promoting immune response. Pollen from plants exposed to air pollutants produce more of these allergy-provoking c...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

A molecule designed to block cat allergies successfully prevented allergic reactions in laboratory mice, as well as in human cells in a test tube, University of California, Los Angeles (UCLA) researchers report in the April issue of Nature Medicine, available online now. In the future, the investigators say, these promising results could lead to a new therapy not only for human cat allergies, but...

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Imaging Mass Spectrometry for Small Molecule Localization from Protein Discovery, Inc.

Description:ions and aligns them with histological images so you can localize drugs and metabolites prior to synthesizing radiolabeled c...
Company:Protein Discovery, Inc.

Small Non-coding RNA Discovery Microarray - Comprehensive Service from LC Sciences

Description:LC Sciences provides a comprehensive microarray service for systematic discovery of small regulatory/functional RNA embedded within non-coding RNAs (ncRNAs) using a novel Paraflo technology and proprietary probe design, which enables highly sensitive and specific direct detection of small RNAs (1). This comprehensive service includes custom probe design (according to submitted target RNA sequence...
Company:LC Sciences

Plasmid DNA Preparation (Small Scale) from Nature Technology Corporation

Description:Highly-purified, endotoxin-free plasmid DNA preparations are prepared from customers high-copy (pUC) plasmids in quantities from 1mg to multi-gram scales. Small-scale (1-100mg) as well as large-scale (100mg-multi-gram) preparations are made according to customer specifications. Each preparation is formulated according to customer needs, and glycerol stocks are maintained to facilitate future or...
Company:Nature Technology Corporation

HIV-1 p24 ELISA Kit, Alliance (480 Tests) from PerkinElmer

Description:The PerkinElmer kit provides reagents for immune complex disruption (ICD) of antigen/antibody complexes in serum and plasma samples using a combination of low pH and heat. The samples are then neutralized and transferred to microplate wells which are coated with a highly specific mouse monoclonal antibody to HIV-1 p24. The immobilized monoclonal antibody captures both free HIV-1 p24 and that whic...
Company:PerkinElmer

CORNING CELL SCRAPER, SMALL ,STERILE from Sigma-Aldrich

Description:Useful for the mechanical harvesting of cells • Blade design minimizes cell damage and ensures even contact with the growth surface • Designed for use in 25 and 75cm flasks • Individually wrapped • Sterilized by gamma radiation and certified nonpyrogenic Linkage: This CLS number is a new product number, created to easily match Cornings product number. If showing no availabi...
Company:Sigma-Aldrich

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New Kit Generates Exceptionally Pure Total RNA for RT-PCR

RT-PCR miniprep kit Stratagene Stratagene has determined that standard RNA purification kits are not satisfactory for reverse transcribed PCR (RT-PCR) applications. We...

A Versatile Power Supply for All Electrophoresis Applications

Douglas Drake Michelle Cayouette Lisa Filippone Bob LeSchofs Stratagene 4000 Power Supply Stratagene has developed the new SmartPower...

Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits

Allelic discrimination kits with excellent specificity, sensitivity, andassay throughput Stratagene Because of their unique hairpin conformation, molecular beacon probes canrecognize single base differences, making them ideal for mutation detection andallelic discrimination. Base...

High-Level Expression of Peanut Allergens Affected by Rare Codon Usage

Biochemical & Molecular Allergology, Research Center Borstel, Germany By using Stratagenes BL21-CodonPlus(DE3)-RIL cells * withextra copies of E. coli, argU, ileY, and leuW tRNA genes,it is possible to attain high-level expression...

The Best Enzyme for the Toughest PCR Challenges Improved with New Hot-Start Feature

DNA pol...

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X-ray crystallography

in a <a href="/ ?q=/ Biology-Definition/ Cr...

Sewall Wright

which led to the <a href="/ ?q=/ Biology-...

Parallel evolution

occurs when two independent species evolve together at the same time in the same ecospace and acquire similar characteristics. is the contemporaneous evolution of the <a href="/ ?q=...

Allostery

. Changes...

Allele frequency

, or equivalently the richness of its <a href="/ ?q=/ Biology-Defi...

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Thallus

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Small nuclear RNA

s are involved in <a...

Small intestine

The . Coils and folding plus villi give this 3m tube the surface area of a 500-600m <a href=...

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Parallel evolution

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Asthma may actually be prevented by Dust and Dirt

National Jewish Medical and Research Center researchers in USA say that a little dust and dirt in the home may help prevent asthma later in life. Environmental endotoxin may have an allergy-protective effect in some infants whose homes have high levels of the bacteria by-product. "Endotoxin seems to drive the immune system to produce cytokines that inhibit certain processes in the body th...

Homeopathic preparation better than placebo in perennial allergic

A homeopathic preparation for perennial allergic rhinitis appears to be more effective than placebo. A multicenter team studied 50 patients with perennial allergic rhinitis. The subjects were randomized to receive either 30cc of a homeopathic preparation of principal inhalent allergen or placebo. In the third and fourth week after the start of treatment, the group compared changes in nasa...

Pancreatitis: Minimially Invasive Procedure Offers Long-Term Pain Relief

Many more patients with chronic pancreatitis can safely turn to a minimally invasive operation for long-term pain relief, according to a new study by Johns Hopkins University physicians. Endoscopic therapy is an effective alternative to more invasive surgery or drugs, says Anthony N. Kalloo, MD, director of GI endoscopy at Hopkins and lead author of the study that appeared in the July...

New vaccine helps allergy and asthma patients

Allergy and asthma patients can now breathe easy. Literally. A new vaccine called grass pollen vaccine has been shown to be effective in improving the quality of life and has also reduced medication requirements in these patients. These and other findings of this study are reported in the latest issue of the Journal of Allergy and Clinical Immunology Samantha M. Walker, PhD, of the Imperi...

New vaccine helps allergy and asthma patients

Allergy and asthma patients can now breathe easy. Literally. A new vaccine called grass pollen vaccine has been shown to be effective in improving the quality of life and has also reduced medication requirements in these patients. These and other findings of this study are reported in the latest issue of the Journal of Allergy and Clinical Immunology Samantha M. Walker, PhD, of the Imper...

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Jameson Muscle Hook - Small

Description:Small bulbous tip with flat sides. Flat serrated handle with polished finish. Overall length: 5.1 inches....
Company:Bausch & Lomb Storz

Symblepharon Ring - Small

Description:Size: Small. 20.50 mm by 22.00 mm. Clear lucite. Supplied sterile....
Company:Bausch & Lomb Storz

Mallory-Head Acetabular Cups

Description:The cementless acetabular shells form part of the Mallory head range of femoral and acetabular implants....
Company:Biomet Orthopedics, Inc

Welch Allyn PanOptic Ophthalmoscope with Cobalt-Blue Filter and Corneal Viewing Lens

Description:The Panoptic ophthalmoscope incorporates an innovative and patented new optical design called axial Pointsource optics. This enabling technology makes it easier to enter small pupils and provides a dramatically wider, more panoramic view of the fundus that's 5X larger than ever before achieved with a standard ophthalmoscope in an undilated eye....
Company:Welch Allyn Medical Products

Welch Allyn PanOptic Ophthalmoscope

Description:The Panoptic ophthalmoscope incorporates an innovative and patented new optical design called axial Pointsource optics. This enabling technology makes it easier to enter small pupils and provides a dramatically wider, more panoramic view of the fundus that's 5X larger than ever before achieved with a standard ophthalmoscope in an undilated eye....
Company:Welch Allyn Medical Products

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New Advances in Gastric Diagnostics: Smaller is Better

In recent years, miniaturization has opened up exciting possibilities in the area of gastric diagnostics. New technology may make routine GI diagnostic procedures as simple as swallowing a vitamin pill-sized encapsulated unit in the not-too-far future, and the present reality is that these units are becoming valuable adjuncts to traditional diagnostics. Capsule endoscopy (enteroscopy...

Bench-Top Centrifuges--Basic Tools for the Small Lab

No matter how elementary or advanced, every clinical laboratory possesses one essential devicea centrifuge. It may be a bench-top or floor model, refrigerated or non-cooled, but this apparatus, because of its unique ability to fractionate liquid specimens by creating spin-induced high g-forces, has long been a standard tool for both diagnosis and research applications. For all this utility, t...

Prothrombin Time Comes in Small (CLIA-Waived) Packages

Determining prothombin levels is necessary to plan or evaluate anticoagulant therapy, to diagnose various inherited conditions, such as hyperhomocystinemia, elevated factor VIII levels, dysfibrinogenemia, factor XII deficiency and disorders of plasmin generation, and to assess acquired conditions, such as pregnancy, postoperative state, antiphospholipid syndrome, hyperhomocystinemia, among ot...

Rapid Flu Tests May Prove Especially Helpful This Season

On October 5, Chiron Corporation notified the CDC that none of its influenza vaccine (Fluvirin) would be available for distribution in the United States for the current influenza season. In the wake of this sudden removal of nearly half of the anticipated American vaccine supply, medical officials and the general public have grown increasingly alarmed about the scarcity of vaccine and the ris...

Low-Density Cholesterol Subfractions: Not all LDL-C Particles are Created Equal

Medical conventions are challenged every day. Already in the new year, the effectiveness of cold medicine and the gold standard in breast cancer treatment have been challenged. Standards in cholesterol testing are the latest casualty of medical innovation. For years, cholesterol has been measured by a simple panel o...

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Goodsall's rule

to its internal opening. Fistulas can be described as anterior or posterior relating to a line drawn in the coronal plane across the anus. Anterior fistulas will have a direct track into the anal canal. Posterior fistulas will have a curved track with t...

Allopathic medicine

as the treatment of disease using conventional medical therapies...

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Walleye

is looking at Rondon (London) and the other is looking at Pari (Paris)...

Valley fever

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Tetralogy of Fallot

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Swallowing pain

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