Biomarkers May Predict Aggressiveness of Prostate Cancer
Cancer expert is wary of finding, however
TUESDAY, May 5 (HealthDay News) --Three molecules associated with prostate cancer might provide the long-sought markers that could discern which tumors are life-threatening and need aggressive treatment, a new study indicates.
The currently ...
New biomarker may predict leukemia aggressiveness
Scientists at the University of California, San Diego and the Moores UCSD Cancer Center have evidence of a potential new biomarker to predict the aggressiveness
of an often difficult-to-treat form of leukemia. They found that high levels of a particular enzyme in the blood are an indicator that ch...
Cartoons to Indicate Aggressiveness in Urban School Girls
Researchers working closely with African American inner city schoolgirls have been developing culturally sensitive drawings of problematic social incidents to help measure// which children are likely to take offense and react aggressively.
"The girls preferred the cartoons over traditional wr...
Predicting the return of prostate cancer: New Johns Hopkins study betters the odds of success
...tion method comprises the length of time it takes for PSA (prostate-specific antigen) to double, Gleason score (a numeric indicator of prostate cancer aggressiveness
as seen under the microscope), and the interval between surgical removal of the prostate and the first detectable PSA level. According to Johns Hopki...
DFG establishes nine new collaborative research centers
...cularisation and substrate transport, will also be addressed. Furthermore, the representation of cytobiological signals will be used for assessing the aggressiveness
of a tumour. Tracer and optical methods will then aid in transferring the molecular imaging from animal experiments to the clinical situation. (Host u...
Gene Mutation May Up Risks of Endometrial Cancer
... Marker indicates aggressiveness
of the disease, study finds,, ,,
WEDNESDAY, May 27 (HealthDay News) -- A genetic marker for aggressive endometrial cancer has been identif...
Research reveals molecular pathway behind invasive prostate cancers
...to determine if their findings were applicable in humans as well.
"Theoretically, this new knowledge could be used to better categorize a tumor's aggressiveness
by measuring the levels of PTEN and Par-4 expressed in a tissue biopsy," adds Diaz-Meco. "That would help clinicians make tough decisions about how ag...
NYU Langone Medical Center's tip sheet to the 45th Annual Meeting of ASCO
...s identified in the study can help predict the likelihood of surviving 18 months after cancer recurrence and whether these miRNAS may help predict the aggressiveness
of the disease in earlier stages of melanoma.
Abstract # 9044, 8 a.m. to noon on Monday, June 1, 2009
Blood-based marker may be tied to poor me...
What killed Naval hero John Paul Jones?
...ccomplishments, Dr. Bogle says he was not well accepted by other officers of his time because of his exaggerated sense of personal honor, over-the-top aggressiveness
and what some said was a poor leadership style. "His need for fame and personal honor, not unusual for officers of his day, drove him to see his men a...
Statins Guard Against Prostate Cancer
...ssive prostate cancer.
In a third report, researchers led by Dr. Stacy Loeb, from Johns Hopkins University, found statins may help in reducing the aggressiveness
of prostate cancer. "Our results suggest that the use of statins may be associated with more favorable pathological features at radical prostatectomy,...
Aggressiveness in Medical Technology
Ipsogen Expands its US Market Presence Through Licensing Agreement With ARUP Laboratories for the Commercialization of JAK2 Molecular Diagnostic Assays
...tests, developed in close cooperation with highly specialized
clinical centres, provide information on the type of disease (diagnosis,
screening), the aggressiveness
of cancer (prognosis), the efficacy of
proposed targeted therapies (companion diagnosis) and the course of the
cancer being treated (monitoring).
Freezing Prostate Cancer Does a Man's Body Good
...results of the prostate-specific antigen (PSA) blood test (which looks for a protein produced by the prostate gland and can help detect cancer), tumor aggressiveness
and the clinical stage of the tumor.
About the Society of Interventional Radiology
Interventional radiologists are physicians who specializ...
Lilly and Deciphera Pharmaceuticals Announce Licensing and Collaboration Agreement
...common in malignant
melanomas, colon, and thyroid cancers. The V600E mutant form of BRAF kinase
in particular has been associated with increased tumor aggressiveness
decreased survival rates in many types of cancers. Deciphera is pursuing
two distinct strategies centered on BRAF inhibition. The first strategy
AviaraDx Confirms That Combination of Two Molecular Biomarkers Improves Prediction of Disease Recurrence in Early Stage Breast Cancer Patients
... are involved in invasive tumor
growth. This assay assists pathologists and oncologists by improving the
accuracy of tumor grading.
To predict tumor aggressiveness
and a potential response to
chemotherapy, pathologists traditionally evaluate a breast cancer biopsy by
light microscopy and assign a tumor grade. Pat...
Karmanos Physician-Scientists Examine Racial Disparities in
Patients with Gynecologic Cancer
...os Cancer Institute, Wayne State University, two
studies were conducted to determine if this stems from the
molecular composition of the tumor, or the aggressiveness
treatment plan. Dr. Schimp's presentation, Outcomes of Endometrial
and Ovarian Cancer Treatment and Ethnicity, was part of the
Molecular Insight Pharmaceuticals, Inc. Presents Preclinical Data
on Molecular Imaging Pharmaceutical for Prostate Cancer
...on the company's products and technologies to be presented at the
"Accurate diagnosis and the ability to properly assess the true
extent and aggressiveness
of prostate cancer are fundamental to
appropriate therapeutic management of the disease," said John W.
Babich, Ph.D., President and Chief Scientific O...
Aggressiveness in Biological News
Changing length of days reverses how estrogen affects aggressiveness in mice
New research shows how simply varying the length of daylight to which mice are exposed to can change how aggressively they react to other mice.
The study found that in the short days of winter, the class of hormones called estrogens acts to increase aggression in males of a particular type of mo...
2 reproductive factors are important predictors of death from ovarian cancer
... in Philadelphia, said these results raise the question "can the amount and/or duration of reproductive hormones to which women are exposed affect the aggressiveness
of ovarian cancer and/or its resistance to treatment, and if so, by what mechanism?"
"The significance of this paper is in suggesting new researc...
Tracking down the causes of multiple sclerosis
New understanding - possible treatments
"Such doubly or even triply activated T cells could be the reason for the significantly greater aggressiveness
of these cells", suggests Hartmut Wekerle, the head of the study. And, of course, he is already thinking one step ahead: "We must now find a way of id...
Tumor growth and chemo response may be predicted by mathematical model
... The aggressiveness
of tumors and their susceptibility to chemotherapy may become easier to predict based on a mathematical model developed at The University of Texas Hea...
Agent Orange exposure increases veterans' risk of aggressive recurrence of prostate cancer
...ime of surgery. And, their cancer came back with a vengeance: the time it took the prostate specific antigen, or PSA, level to double an indicator of aggressiveness
was eight months versus more than 18 months in non-exposed veterans.
"There is something about the biology of these cancers that are associated wi...
CSHL team develops mouse models of leukemia that predict response to chemotherapy
...udy traces the intracellular network controlled by the p53 gene, a linchpin of the cell's anti-tumor defense response, as the key determinant of AML's aggressiveness
and response to therapy.
Most patients with AML receive the same standardized treatment an initial phase of intense chemotherapy followed by addi...
Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment
...ad to other organs or not." says the Georgia Cancer Coalition Distinguished Cancer Scholar. "We want to find clinical markers that supplement PSA."
is a major factor in prostate cancer treatment. In fact some men with slow growing disease likely won't even need treatment. So he wants to provide a ...
U-M researchers ID gene involved in pancreatic cancer
...the group in which ATDC was not expressed, only minimal signs of tumor growth were seen after 60 days.
"This particular gene promotes the biologic aggressiveness
of the cancer," says Simeone, who is also Lazar J. Greenfield Professor of Surgery and Molecular & Integrative Physiology at the U-M Medical School.
Stroma genomic signature predicts resistance to anthracyclin-based chemotherapy in breast cancer
...nd computational biologists combined their effort to address a very puzzling question: Why breast tumors that have very similar conditions in terms of aggressiveness
(grade), invasiveness (node status) and hormone dependency (ER status), respond differently to the same kind of chemotherapy treatment.
Dense tissue promotes aggressive cancers
...sed risk for both developing breast cancer and having breast cancers with invasive characteristics.
This connection between breast density and cancer aggressiveness
has begged the question of which comes first. Is the tissue denser because the tumor is more aggressive (and recruits cells that "lay down" more matri...
Aggressiveness in Biological Technology
Aggressiveness in Biological Definition
...om these children, it is also difficult to determine what the survival rate or prognosis would be for the condition if they were treated with the same aggressiveness
as their genetically 'normal' peers.
The rate of occurance for Edward's Syndrome is ~ 1:3000 conceptions and 1:6000 livebirths, as 50% of those diag...
... was not Jewish), and Tobach.
Science and sociobiology
Twin studies suggest that behavioural traits such as creativity , extroversion and aggressiveness
are between 45% to 75% genetic. Intelligence is said by some to be about 80% genetic after one matures. Others, such as R. C Lewontin, reject the i...