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agents in Medical News

While Some New Agents Will Achieve Strong Sales, the Migraine Drug Market Will Decline $1.3 Billion by 2018 as Generic Erosion Takes Toll on Top-Selling Brands

WALTHAM, Mass., Aug. 5 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that although sales of emerging therapies will partially offset losses to generic competitors, the migraine dr...

Generic Erosion of Established Agents Will Offset Growth From Uptake of Emerging Therapies in the Market for Benign Prostatic Hyperplasia and Male Lower Urinary Tract Symptoms

WALTHAM, Mass., Aug. 3 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, from 2013 to 2018, generic erosion of established agents--most notably tamsulosin--will cause a decline of more than eig...

Increasing Diagnosis Rates and Growing Use of Key Agents Such as Pfizer's Lyrica Will Drive Eight Percent Annual Growth in the Fibromyalgia Drug Market Through 2018

WALTHAM, Mass., July 13 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that increased use of key agents such as Pfizer's Lyrica, Eli Lilly/Boehringer Ingelheim's Cymbalta/Xeristar/Ariclaim and Forest Labora...

New oral agents may prevent injury after radiation exposure

(Boston) Researchers from Boston University School of Medicine (BUSM) and collaborators have discovered and analyzed several new compounds, collectively called the ''EUK-400 series,'' which could someday be used to prevent radiation-induced injuries to kidneys, lungs, skin, intestinal tract and b...

Launch of Targeted Agents and Increased Use of Maintenance Therapy Will Drive the Non-Small-Cell Lung Cancer Drug Market to Nearly Triple to Almost $10 Billion in 2018

Emerging Agents from Pfizer, AstraZeneca, GlaxoSmithKline, Bayer/Onyx and Boehringer Ingelheim, and Increased Use of Existing Agents from Eli Lilly and Roche Will Drive Growth, According to a New Report from Decision Resources WALTHAM, Mass., June 29 /PRNewswire/ -- Decision Resources, one of...

New Therapies, Including Novel Biologic Agents from Elan/Wyeth and Eli Lilly, Will Drive Robust 11 Percent Annual Growth In the Alzheimer's Disease Market

Sales of Acetylcholinesterase Inhibitors, Which Currently Dominate the Market, Will Decline by $1 Billion from 2008 to 2018, According to a New Report from Decision Resources WALTHAM, Mass., June 17 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for...
agents in Medical Technology

Responses After Completion of Therapy Increase Pixantrone Complete Remission (CR)/Unconfirmed Complete Remission (CRu) Rate to 24% and Overall Response Rate (ORR) to 40% Compared to 7% and 14% for Comparator Agents in Phase III EXTEND Trial in 3rd Line Th

SEATTLE, June 22 /PRNewswire-FirstCall/ -- Updated follow-up phase III EXTEND (PIX 301) clinical trial data enhances previously reported superior response rates for pixantrone over comparator including in high risk patient subgroups Additional Clinical Studies Also Highlighted at Pan ...

Carbapenems and Other Agents that Provide Broad-Spectrum Activity are Preferred by Surveyed Physicians for the Treatment of Intra-Abdominal Infections

A Drug's Activity Against Anaerobes is the Leading Attribute in Antibiotic Selection, According to a New Report from AMR and Decision Resources MALVERN, Pa. and WALTHAM, Mass. , May 27 /PRNewswire/ -- Arlington Medical Resources (AMR) and Decision Resources find that surveyed physicians will...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

- Combination of R7227, protease inhibitor, and R7128, nucleoside polymerase inhibitor, shows significant potency in reducing viral load in patients with hepatitis C - NUTLEY, N.J., BRISBANE, Calif., and PRINCETON, N.J., April 25 /PRNewswire-FirstCall/ -- Roche, InterMune, Inc. (Nasdaq: IT...

Surveyed Neurologists Anticipate That Less Than 30 Percent of Their Use of Emerging Oral Agents in Multiple Sclerosis Will be in the First Line

Only 39 Percent of Newly Diagnosed Patients Receive a Drug Within One Year of Their First Diagnosis, According to a New Report from Decision Resources WALTHAM, Mass., April 15 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceut...

Pixantrone Increases Progression-Free Survival by 81% Compared to Standard Chemotherapeutic Agents in Phase III Relapsed Aggressive non-Hodgkin's Lymphoma Trial

SEATTLE, Jan. 28 /PRNewswire-FirstCall/ -- Cell Therapeutics (CTI) (Nasdaq and MTA: CTIC) announced today preliminary progression-free survival (PFS) results from its pivotal phase III EXTEND (PIX301) trial of pixantrone that show patients with advanced, relapsed aggressive non-Hodgkin's lymph...

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

SAN FRANCISCO, Dec. 6 /PRNewswire/ -- Researchers today report that after the implementation of Medicare coverage limitations for erythropoiesis-stimulating agents (ESAs), a significantly greater proportion of anemic cancer patients who were on chemotherapy and who received ESAs needed blood trans...
agents in Medical Products

Wampole ISOSTAT/ISOLATOR Microbial System

Description:...a occur yearly in the U.S., with a 40-50% mortality rate. Rapid isolation of the organism and the determination of its susceptibility to antimicrobial agents are essential. The Wampole ISOSTAT/ ISOLATOR Microbial System is a blood culture method based on lysis centrifugation. This technology is used to conc...
Company:Inverness Medical Innovations

Lactic Acid Treatments

Description:... Lactic Acid is a non-irritating rapid exfoliator. Lactic Acid is is recommended for those that are new to peel and exfoliating agents in skin care products, as well as those that have used other exfoliators for a long period and want to improve results. Lactic Acid is a naturally oc...
Company:Natural Skin Shop

Physicians' Cancer Chemotherapy Drug Manual 2005

Description:...provides a comprehensive, easy to use catalog of over 100 drugs both on and off label commonly used in cancer treatment. This new edition includes new agents (recently or about to be FDA approved)....
Company:Skyscape, Inc.

BloodSTOP Hemostatic Gauze

Description:...und from infection. LifeScience PLUS makes two hemostatic gauze products: BloodSTOP and BloodSTOP iX. They are both water-soluble hemostatic agents made from the finest completely natural cellulose. BloodSTOP hemostatic gauze is often used externally because of its cost-effectiveness; it is made o...
Company:LifesciencePlus

TaqScreen West Nile Virus Test

Description:...hours. In addition to its applications in nucleic acid fingerprinting and the diagnosis and monitoring of disease, PCR enables detection of infectious agents in donated blood earlier in the infection cycle, often before symptoms appear. Standard immunoassay testing, in contrast, detects evidence of a bodys ...
Company:Roche Molecular Systems, Inc.

InfusO.R. Pump

Description:... The InfusO.R. Pump is a syringe infusion device that will aid in the administration of many intravenous agents given during anesthetic procedures. It provides for the convenient delivery of narcotics, muscle relaxants, and vasoactive drugs through the SMART LAB...
Company:Baxter Healthcare
agents in Medical Dictionary

Viral Hemorrhagic Fever

...of illnesses ... Some forms of the viral hemorrhagic fever disease are associated with kidney failure. ... Viral hemorrhagic fever agents (VHFs) include numerous zoonotic diseases, all of ... case or suspect, record " Viral . Hemorrhagic Fever " as the disease being ... In most ...

Vas deferens

... However, in rat vas deferens and rat distal colon, cGMP-elevating agents such as ... In rat vas deferens , 5 mM SNP increased cGMP levels (14-fold) and PKG activity ... Definition of vas from the Merriam-Webster On...

Uremia

... Kidney Patients ... Nonetheless, the terms uremia or uremic poisoning have persisted, and now mean ... These drugs are the only therapeutic agents that are truly societal drugs, ... presence of remote infection, uremia , hepatic disease, kidney disease and ... List of 61 causes of Ure...

Toxins

... ... Without the kidneys, waste products and toxins would soon build up in the blood ... Toxins are sometimes classified as chemical warfare agents and sometimes as ... Toxins have been used periodically in warfare. ... At the same time, microbial toxins , being influenced by the vast numbe...

Thrombolytic therapy

...ithrombotic Dosing and Algorithms, Information ... Bleeding is the major complication of thrombolytic therapy . ... INTRODUCTION Thrombolytic agents activate plasminogen to form plasmin, resulting ... The evidence suggests that thrombolytic therapy accelerates clot lysis and is ... Throm...

Surfactant

... Surfactants are wetting agents that ... The term surfactant is a blend of surface acting agent. ... Retrieved from "http://en.wikipedia.org /wiki/ Surfactant " ......
agents in Biological News

Structure of enzyme against chemical warfare agents determined

This release is available in German . The enzyme DFPase from the squid Loligo vulgaris , is able to rapidly and efficiently detoxify chemical warfare agents such as Sarin, which was used in the Tokyo subway attacks in 1995. A detailed understanding of the mechanism by which enzymes ca...

Chemopreventive agents in black raspberries identified

PHILADELPHIA A study published in Cancer Prevention Research , a journal of the American Association for Cancer Research, identifies components of black raspberries with chemopreventive potential. Researchers at the Ohio State Comprehensive Cancer Center found that anthocyanins, a class of fl...

MIT nanotubes sniff out cancer agents in living cells

CAMBRIDGE, Mass.--MIT engineers have developed carbon nanotubes into sensors for cancer drugs and other DNA-damaging agents inside living cells. The sensors, made of carbon nanotubes wrapped in DNA, can detect chemotherapy drugs such as cisplatin as well as environmental toxins and free radical...

Certain anticancer agents could be harmful to patients with heart disease

A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis. The anticancer drugs which go by the strange name of hedgehog antagonists interfere with a biochemical process that ...

Drug aimed at 2 bioterror agents blocks live viral infection, Weill Cornell team reports

NEW YORK (Dec. 19, 2007) -- Two deadly and highly infectious viruses -- both potential bioterror threats -- may have met their match in a new drug developed by scientists at Weill Cornell Medical College in New York City. Hendra and Nipah viruses are related, newly recognized zoonotic viruses t...

New insights into the diversity of Creutzfeldt-Jakob disease agents

Researchers from the United Kingdom and France have identified four separate biochemical subgroups in a selection of cases of Creutzfeldt-Jakob disease. The study, published March 14th in the open-access journal PLoS Pathogens, suggests that these subgroups could represent distinct prion strains i...
agents in Biological Technology

Structure of enzyme against chemical warfare agents determined

This release is available in German . The enzyme DFPase from the squid Loligo vulgaris , is able to rapidly and efficiently detoxify chemical warfare agents such as Sarin, which was used in the Tokyo subway attacks in 1995. A detailed understanding of the mechanism by which enzymes ca...

Structure of enzyme against chemical warfare agents determined

This release is available in German . The enzyme DFPase from the squid Loligo vulgaris , is able to rapidly and efficiently detoxify chemical warfare agents such as Sarin, which was used in the Tokyo subway attacks in 1995. A detailed understanding of the mechanism by which enzymes ca...

Structure of enzyme against chemical warfare agents determined

This release is available in German . The enzyme DFPase from the squid Loligo vulgaris , is able to rapidly and efficiently detoxify chemical warfare agents such as Sarin, which was used in the Tokyo subway attacks in 1995. A detailed understanding of the mechanism by which enzymes ca...

Peramivir Phase 2 Data for the Treatment of Outpatient Influenza to be Presented at the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy

BIRMINGHAM, Ala., Oct. 20 /PRNewswire-FirstCall/ -- BioCryst Pharmaceuticals (Nasdaq: BCRX ) and partner Shionogi & Co., Ltd. (Shionogi) today announced that positive Phase 2 data on peramivir, a potent neuraminidase inhibitor for the treatment of influenza, has been accepted as a late-breaker...

Use of Biologic Agents Continues to Expand Among US Rheumatologists - Can New Agents Shift the Treatment Paradigm in Rheumatoid Arthritis?

EXTON, Pa., Sept. 17 /PRNewswire/ -- BioTrends Research Group, Inc. released its third annual TreatmentTrends(TM): The Use of Biologic Agents in Rheumatology publication, providing insight into the management of Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Ankylosing Spondylitis (...

Study From the University of Texas M.D. Anderson Cancer Center Demonstrates That AHCC(R) is Safe in Combination With Most Chemotherapeutic Agents

Supports safety of AHCC for cancer patients undergoing chemotherapy PURCHASE, N.Y., Nov. 6 /PRNewswire/ -- A recently published study in the Journal of the Society for Integrative Oncology (Vol. 6, No. 3 (Summer), 2008: pp 105-109) by researchers at the University of Texas M.D. Anderson Ca...

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agents in Biological Products

Rosmarinic acid from Biotrend Chemikalien GmbH

Description:...PAC: [R-(+)]-alpha-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid Literature: 1. Van Kessel et al. (1985) agents Actions 17:375; 2. Bult et al. (1985) Br J Pharmacol 84:317; 3. Rampart et al. (1986) Biochem Pharmacol 35:1397; 4. Sahu et al. (1999) Biochem Pharmac...
Company:Biotrend Chemikalien GmbH

ReBlot Plus Kit from CHEMICON

Description:...s, such as Sepharose conjugates, have been reused many times without compromising antigen-antibody reactivity, the need for pH extremes and chaotropic agents has precluded the application of these methods to Western blotting. The CHEMICON Re-Blot Plus Western Blot Mild Antibody Stripping Solution contains ...
Company:CHEMICON

GIBCO Cell Dissociation Buffer enzyme free PBS-based from Invitrogen

Description:...e-filtered isotonic and enzyme-free aqueous formulations of salts chelating agents and cell-conditioning agents in either Ca2+- and Mg2+-free Hanks' balanced salt solution or Ca2+- and M...
Company:Invitrogen

GIBCO Cell Dissociation Buffer enzyme free Hanks'-based from Invitrogen

Description:...e-filtered isotonic and enzyme-free aqueous formulations of salts chelating agents and cell-conditioning agents in either Ca2+- and Mg2+-free Hanks' balanced salt solution or Ca2+- and M...
Company:Invitrogen

microPET Focus 120 from CTI Molecular Imaging, Inc.

Description:...rld are using microPET scanners to Study animal models of human disease Study genetically engineered animals Assess new pharmacological agents in drug development Assess novel drug delivery and gene therapy approaches Develop new molecular imaging assays Develop new radiotracer...
Company:CTI Molecular Imaging, Inc.

microPET R4 from CTI Molecular Imaging, Inc.

Description:...rld are using microPET scanners to Study animal models of human disease Study genetically engineered animals Assess new pharmacological agents in drug development Assess novel drug delivery and gene therapy approaches Develop new molecular imaging assays Develop new radiotracer...
Company:CTI Molecular Imaging, Inc.

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agents in Biological Definition

Computed axial tomography

...r accidents and intracranial hemorrhage is the most frequent reason for a "head CT" or "CT brain". Scanning is done without intravenous contrast agents (contrast may resemble a bleed). CT generally does not exclude infarct in the acute stage, but is useful to exclude a bleed (so anticoagulant medi...

Diabetes mellitus

...ral medications, including high dose glucocorticoids , some chemotherapy agents (especially L-asparaginase), and some of the antipsychotics and mood stabil...n). In addition, the onset and duration of the effects of oral hypoglycemic agents vary from type to type and from patient to patient. A useful test that c...

Ecdysone

...of arthropods but also occur in other invertebrates where they can play different role. Ecdysteroids also appear in many plants mostly as a protection agents (toxins or antifeedants) against herbivore insects. ...

Gel electrophoresis

... tend to fold up into molecules with complex shapes and migrate through the gel in a complicated manner based on their tertiary structure. Therefore, agents that disrupt the hydrogen bonds , such as sodium hydroxide or formamide , are used to renature the nucleic acids and cause them to behave as long ...

Gel electrophoresis

... tend to fold up into molecules with complex shapes and migrate through the gel in a complicated manner based on their tertiary structure. Therefore, agents that disrupt the hydrogen bonds , such as sodium hydroxide or formamide , are used to renature the nucleic acids and cause them to behave as long ...

Photosynthesis

...photosynthetic bacteria. Aside from the cyanobacteria , they use reducing agents such as sulfide or hydrogen , so no oxygen is produced. Others, such a...olated chloroplasts give off oxygen in the presence of unnatural reducing agents like iron oxalate , ferricyanide or benzoquinone after exposure to light...
agents in Biological Dictionary

Alkylating agents

Alkylation is the transfer of an alkyl group from one molecule to another. The alkyl group may be transferred as an alkyl carbocation, a free radical, a carbanion or a carbene . Alkylating agents are widely used in chemistry... An alkylating antineoplastic agent is an alkylating agent us...

Uropod

.... ... The uropod , a protrusion at the rear of amoeboid motile cells such as leukocytes, ... Remodelling of cell shape by uropod -interfering agents disturbs cell migration. ... ...

Topoisomerase

... in Vitro by Bioactive Benzene Metabolites, ... Topoisomerase -interactive agents make up one recently identified class of ... Type I topoisomerase Ty... IA and type IB Topoisomerase inhibitor Topoisomerase inhibitors are agents designed to interfere with the action of topoisomerase enzymes [ 1 ] ...

Synergism

...ergism , in general, may be defined as two or more agents working together to produce a result not obtainable by any of the agents independently. The word synergy or synergism com...gy n. , pl. -gies . The interaction of two or more agents or forces so that their ... Synergism Hypothesis...

Retrovirus

...ules. ... The term "retro" in retrovirus refers to this reversal of ... Popular description of the life cycle of retroviruses . ... HIV-2, the agents that cause AIDS, are retroviruses . ... A typical, "minimal" retrovirus consists of: ... A retrovirus is a type of RNA virus that contains t...

Reducing agent

...he following reaction: Reactions- Reducing agents Other kinds of reductants are hydride transfer .....or polar double bonds, most ... Acidic Reducing agents . If you look at the reducing agents above, you will note ... The Relative Strength...
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(Date:9/30/2014)... 30, 2014 (HealthDay News) -- Sleep apnea is a potential ... points to a possible culprit behind the disorder: a "fat" ... fat deposits are increased in the tongue of obese patients ... co-director of the Sleep Center at the University of Pennsylvania ... , which will publish the findings Oct. 1. Sleep ...
Breaking Medicine News(10 mins):Health News:Indosoft Announces Q-Suite Support For Sangoma Lyra 2Health News:Bob Seger Presale Tickets: QueenBeeTickets.com Delights Fans with Discounted Tickets for All 20 Stops on Seger’s “Ride Out” Tour with The Silver Bullet Band 2Health News:Developing countries should enroll medical and nursing students from rural areas 2Health News:Developing countries should enroll medical and nursing students from rural areas 3Health News:Recessions May Thwart a Woman's Motherhood Plans Forever: Study 2Health News:Recessions May Thwart a Woman's Motherhood Plans Forever: Study 3Health News:Could a 'Fat Tongue' Be a Factor in Sleep Apnea? 2
(Date:9/29/2014)... the exposure to tar tended to be lower for ... Similarly, exposure to nicotine tended to be lower. , ... in several countries around the world. Previous studies have ... the smoke of these cigarettes are lower than those ... in the smoke are not necessarily linked to a ...
(Date:9/29/2014)... Monday, September 29: Between 1970 and 2010 populations ... the globe dropped 52 percent, says the 2014 ... Fund (WWF). This biodiversity loss occurs disproportionately in ... of high-income countries. , In addition to the ... point to other warning signs about the overall ...
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Breaking Biology News(10 mins):Slim cigarette smokers not exposed to more harmful chemicals 2Half of global wildlife lost, says new WWF report 2Chefs move to schools can increase school meal participation and vegetable intake among students 2
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