Agent

New drug shows promise as powerful anticancer agent

Research published in the March issue of the journal Cancer Cell describes a small molecule inhibitor of polo-like kinase1 (Plk1) that could lead to a new avenue for targeted cancer therapy. The compound, ON01910, is a potent inhibitor of human tumors in a mouse model system and has low toxicity. The results of this study have led to clinical evaluation of this compound in phase I clinical trials...

To control germs, scientists deploy tiny agents provocateurs

Aiming to thwart persistent bacterial infections and better control group behaviors of certain microorganisms, scientists are creating artificial chemicals that infiltrate and sabotage bacterial "mobs." Reporting the work here today (March 13) at the 229th national meeting of the American Chemical Society, University of Wisconsin-Madison chemistry professor Helen Blackwell described the o...

'Gadonanotubes' greatly outperform existing MRI contrast agents

Researchers at Rice University, the Baylor College of Medicine, the University of Houston and the Ecole Polytechnique Fédérale de Lausanne in Switzerland have created a new class of magnetic resonance imaging (MRI) contrast agents that are at least 40 times more effective than the best in clinical use. The new agents -- dubbed gadonanotubes -- use the same highly toxic metal, gadolinium, t...

Tiny avalanche photodiodes target bioterrorism agents

After the anthrax attacks in the United States in 2001 the threat of a larger and more deadly bioterrorism attack -- perhaps from smallpox, plague or tularemia -- became very real. But the ability to detect such biological agents and rapidly contain an attack is still being developed. In a significant finding, researchers at Northwestern University's Center for Quantum Devices have demonst...

Software 'agents' could help unmask reality of disease clusters

Concerns over the privacy of patients could be hampering efforts to spot disease clusters and monitor the health effects of environmental pollution, according to researchers in the latest edition of the Data made available to research groups investigating everything from cancer clusters to the risk of living near to hazardous waste sites is often r...

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Agent at Biology Products

Cleland’s Reagent from Calbiochem

Description:Contaminants: Heavy metals: ≤1 ppm.<...
Company:Calbiochem

Cleland’s Reagent, ULTROL^® Grade from Calbiochem

Description:...
Company:Calbiochem

GenomONE-Neo EX HVJ-E 4 vial(s) Transfection Reagents from Cosmo Bio Co., Ltd.

Description:HVJ (hemagglutinating virus of Japan, also named Sendai virus) Envelope VECTOR KIT is a tool for transfection of molecules by means of membrane fusion. Most efficient transfection are for siRNA (RNAi), Protein, Oligo, cDNA, Antibodies, Vector, and Biomolecule in vitro and in vivo. GenomONE-Neo EX has a high fusing capability in short period of time that benetif sensitive primary cells or tissues...
Company:Cosmo Bio Co., Ltd.

Cleland’s Reagent, Molecular Biology Grade from Calbiochem

Description:...
Company:Calbiochem

Cleland’s Reagent from Calbiochem

Description:Contaminants: Heavy metals: ≤1 ppm.<...
Company:Calbiochem

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Agent at Biology Technology

Brilliant Core Reagent Kits for QPCR and QRT-PCR

Economical quantitative PCR (QPCR) reagent kits for use with all types offluorescent probes Stratagene Stratagenes Brilliant quantitative PCR and RT-PCR corereagent kits are compatible with many fluorescent detectiontechnologies. Sever...

A Comparison Study of Lipid Tranfection Reagents in A549, NIH 3T3 and COS-7 Cell Lines

Genetic Applications LLC transfection reagent canbe used for simple and reproducible delivery of foreign DNA into mammaliancells. In this study, we used varying amounts of LipoTAXI transf...

Versatile Transfection Reagent Offers Low Toxicity and Consistent Performance

Stratagene transfection reagent offersimproved, consistent transfections for both adherent cells and cells growing insuspension. In this article, we summarize the results of several experimentsthat characterize the eff...

High-Efficiency Transfections Achieved with New Low-Toxicity Reagent

Nonliposomal formulation yields high efficiencies in a variety oftransfection conditions Stratagene Introducing foreign DNA into eukaryotic cells requires high-potencytransfections, which demand superior quality transfection reagents that areefficient, have low toxicity, and wor...

Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock Gel-Heavy

Phase Lock Gel may be used in conjunction with TRIzol Reagent for the isolation of total RNA from cell and tissue samples. Increased yields are observed using this method, because the entire aqueous phase can be recovered without interphase contamination. Below is a protocol outlining the steps involved in RNA...

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Agent at Biology Dictionary

Reducing agent

Pertaining to the <a href="/ ?q=/ Biology-Diction...

Antimicrobial agent

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Alkylating agents

when the analog is incorporated in replicating the <a href="...

Agent at Medicine News

Effective And Economical Agent For Anthrax

As anthrax and other biological weapons continue to be worrisome threats, common pest control agent called methyl bromide is more effective and cheaper// than current treatments in eradicating deadly bacterial spores from buildings. Tests indicate that the methylbromide - used for more than 50 years to control insect pests in buildings, grain elevators and fresh fruit - is a better option than cu...

New target for antidiabetic agents identified

U.S. researchers have identified a protein that could serve as a new target for drugs designed to treat type II diabetes. The protein, known as TRB3, is actually a homolog of a protein found in the fruit fly Drosophila tribbles, senior author Dr. Marc Montminy, from the Salk Institute for Biological Studies in La Jolla, California, and colleagues note. The focus on TRB3 was the result of a...

Gold Nanoparticles: Agents For Noninvasive Cancer Therapy

Gold nanoparticles are potential and very practical agents in therapeutic applications. Researchers from the University of California, San Francisco and Georgia Institute of Technology, writing Cancer Letters // (Available online 28 September) demonstrate the efficiency of gold nanospheres as photothermal agent by selectively delivering gold nanoparticles to oral carcinoma cells that overexpress...

A potent causative agent of dental flourosis: Fluoride

According to many studies pertaining to dental health a common concern is fluoride which is not stopping cavities and is causing discoloured teeth.// This is a revelation of several studies to be presented at the American Association for Dental Research's annual meeting from March 8, 2006, in Orlando, Florida. Some important findings and studies are as mentioned. A...

Another causative agent of adult onset asthma : Atopy

According to new research, asthma is also caused by hereditary predisposition. Atopy is a determining factor in new cases on adult-onset asthma and that avoiding allergens may help prevent adults from developing asthma.//Journal of Allergy and Clinical Immunology (JACI) has the study “Are atopy and specific IgE to mites and molds important for adult asthma?” cited. The study was condu...

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Agent at Medicine Products

Bilirubin Direct Reagent

Description:Intended for the quantitative determination of direct bilirubin in serum. Modified EvelynMalloy Method. Endpoint Reaction. Wavelength: 555 nm. Linearity: 20 mg/dl (340 mol/l)...
Company:Hemagen Diagnostics, Inc.

Bilirubin Total Reagent

Description:Intended for the quantitative determination of total bilirubin in serum. Modified evelynmalloy method. Endpoint reaction. Wavelength: 555 nm. Linearity: 20 mg/dl (340 mol/l)...
Company:Hemagen Diagnostics, Inc.

Direct Bilirubin Reagent

Description:For the quantitative determination of direct bilirubin in human serum. Linearity: 20 mg/dl...
Company:Teco Diagnostics

Total Bilirubin Reagent

Description:For the quantitative determination of direct bilirubin in human serum. Linearity: 20 mg/dl...
Company:Teco Diagnostics

BUN Liquidplus Reagent

Description:Intended for the quantitative determination of urea nitrogen in serum. Reaction: kinetic. Wavelength: 340 nm. Linearity: 150 mg/dL (53.4 mmol/L urea) at 37C....
Company:Hemagen Diagnostics, Inc.

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Agent at Medicine Technology

Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse

In keeping with the recent proliferation of rapid, easy-to-use diagnostic tests, many assays and collection products have entered the marketplace to help clinicians assess dosage appropriateness of therapeutic drugs and to screen for the presence of drugs of abuse. Some of these products require laboratory support while many simple test kits are suitable for point of care use by medical profe...

Prolexys Pharmaceuticals and Columbia University Researchers Publish Study on Anti-Tumor Properties of a Selective Small Molecule Anti-Tumor Agent With Novel Mechanism of Action

SALT LAKE CITY, June 14, 2007 /PRNewswire/ -- ProlexysPharmaceuticals and announced today a publication describing theproperties of the selective small molecule anti-tumor agent,erastin. Prolexys and Columbia applied the company'schemi-proteomics technology to understand the mechanism of actionof erastin. The results, to be published in the June 14, 2007 issueof the journal Nature reveal...

Sunesis Pharmaceuticals Reports Positive Data From Studies of Two Anti-Cancer Agents, SNS-595 and SNS-032, at the 12th Congress of the European Hematology Association

Interim Data from Phase 1 Clinical Trial of SNS-595 in AcuteLeukemia Demonstrates Additional Clinical Activity SOUTH SAN FRANCISCO, Calif., June 11, 2007/PRNewswire-FirstCall/ -- Sunesis Pharmaceuticals, Inc. presentedpositive data from clinical studies of two of the company'santi-cancer product candidates, SNS-595 and SNS-032, at the 12thCongress of the European Hematology Association (E...

Abraxis BioScience Presents Data from Pre-Clinical Study That Provide Evidence for Chemotherapy-Induced Angiogenesis and Rationale for Combining nab-Paclitaxel (Abraxane) with Anti-Angiogenic Agents to Increase Tumor Response

LOS ANGELES--(BUSINESS WIRE)--Apr 19, 2007 - Abraxis BioScience,Inc. (NASDAQ:ABBI), an integrated, global biopharmaceuticalcompany, discussed results from two pre-clinical studies thatprovide evidence for chemotherapy induced angiogenesis andrationale for combining nab-paclitaxel (ABRAXANE(R) for InjectableSuspension (paclitaxel protein-bound particles for injectablesuspension) (albumin-bou...

Kosan Presents Preclinical Data on Nuclear Export Inhibitors, Novel Anticancer Agents, at AACR

HAYWARD, Calif., April 18, 2007 /PRNewswire-FirstCall/ -- KosanBiosciences Incorporated today presented preclinical data on itsproprietary nuclear export inhibitors (NEI) showing induction ofpotent, fast-acting and long-lasting anticancer activity with ahigh degree of tolerability in multiple human tumor xenograftcancer models. Kosan's NEIs are potent, specific inhibitors of CRM1,...

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Agent at Medicine Definition

Disease causative agent

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