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Active Vaccine Prevents Mice From Developing Prion Disease

NYU School of Medicine scientists have created the first active vaccine that can significantly delay and possibly prevent the onset of a brain disease in mice that is similar to mad cow disease. The new findings, published online this week in the journal Neuroscience, could provide a platform for the development of a vaccine to prevent a group of fatal brain diseases caused by unusual infectious...

Unlike other mammals, newborn dolphins and orcas stay active 24/7 during first months of development

If you thought the sleep-deprived months with your newborn were tough, pity the poor mother dolphin or killer whale. Reporting in the June 30 edition of the peer-reviewed journal Nature, UCLA/Veterans Affairs neuroscientists report a developmental pattern in bottlenose dolphins and killer whales that is unique from other mammals, with calves of both species active 24 hours a day during th...

Interactive 3-D atlas of mouse brain now available on web

Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have just launched a web-based 3-D digital atlas browser and database of the brain of a popular laboratory mouse (see "Neuroscientists around the world can now download these extremely accurate anatomical templates and use them to map ot...

Attractive birds more immune against bird flu

A research team at Uppsala University, Sweden has shown in a new study, published in the journal Acta Zoologica, that the size of the spot on a male collared flycatcher's forehead reflects how well the immune defence system combats viruses such as avian influenza. The white spot is also attractive to female birds searching for a mate. Evolutionary biologists have long attempted to explain...

Bioactive cement scaffold may improve bone grafts

A new technology for implants that may improve construction or repair of bones in the face, skull and jaw, has been developed by researchers from the American Dental Association Foundation (ADAF) and the National Institute of Standards and Technology (NIST). Described in recent and upcoming journal articles,* the new technology provides a method for making scaffolds for bone tissue. The s...

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Fragment Library I: Large Volume with mixtures from ActiveSight

Description:Individual compounds are dissolved in DMSO at ca. 200 mM, mixtures of 4 are at ca. 50 mM. Supplied in 5 96-well trays. Dilute library with protein c...
Company:ActiveSight

Bioactive Peptide synthesis from Primm Biotech, Inc.

Description:Custom design The Bioactive peptides are molecules of peptidic nature or origin which display a biological behaviour or activity which can be developed at the industrial level for pharmaceutical, diagnostic, chemical and agro-food applications. In this way it is possible to obtain modified peptides with superior properties for therapeutic applications. Primm offers a design strategy for devel...
Company:Primm Biotech, Inc.

Fragment-based Screening Services from ActiveSight

Description:ActiveSight, the leading provider of X-ray crystallography services for structure-based drug design, offers fragment-based screening services to its pharmaceutical and biotechnology clients. Fragment-based screening involves the binding of drug-like fragments to the active sites of crystallized protein drug targets, allowing scientists to develop novel, high-affinity inhibitors. Relying on state-...
Company:ActiveSight

Anti-GLP-1 (7-36) (Glucagon-like peptide-1), C-terminus amide-reactive Polyclonal Antibody, Unconjugated from CHEMICON

Description:Glucagon-like peptide-1(7-36) amide (GLP-1), C-terminal reactive. Cross-reacts fully with GLP-1(1-36) amide but shows <0.1% cross reactivity with the unamidated forms GLP-1(7-37) and GLP-1(1-37) or other related peptides such as hGLP-2, glucagon, hGIP and VIP.SPECIES REACTIVITIES: Most mammalian species. GLP-1 is identical in all mammalian species studied except guinea pig and presumably its S...
Company:CHEMICON

Adept HPLC System 9, Isocratic Refractive Index from Cecil Instruments Ltd.

Description:The excellent isocratic refractive index chromatography system, uses the CE 4700. Data processing is provided by the CE 4900 interface and software. Solvent delivery is by the high pressure CE 4100 dual piston pump. A column heater can be supplied. The system can be upgraded to provide binary or ternary gradient separations. The supplied an...
Company:Cecil Instruments Ltd.

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Production of Full-Length, Biologically Active MEK1WT and MEK1CA

Stratagene Cloning Systems, Inc. Stratagene has successfully expressed and purified recombinant, wild-typehuman MEK1 )using the ESP yeast pro...

Highly Active and Removable AffinityTagged Lambda Phosphatase

Dualspecificity Lambda Phosphatase useful for dephosphorylation serine,threonine or tyrosine residues Stratagene Cloning Systems, Inc. Stratagene's recombinant Lambda Phosphatase is a dualspecificity proteinphosphatase that has been produced as a fusion to Stratagene's novel affinitytag, the calmodulin...

Madison start-up bets on interactive future for reading education

The company...

Icon Interactive creates new Web monitoring tool

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Improved software makes direct mail an attractive option

EAU CLAIRE, WI - Many businesses, large and small, view direct mailing as a hit-or-miss attempt to reach potential customers and grab their attention. Postalsoft Business Edition 7.32c is a software system designed to give organizations more control over the direct mail process, and to make this form of marketing a more affordable option for mid to large-volume mailers. The newly-improv...

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Radioactive Seeds used in Prostate Cancer treatment can migrate with the body

In a shocking disclosure, Dr. Murali Ankem, a resident in Urology at the Robert Wood Johnnson Medical Centre of the University of New Jersey Medical and Dental School, New Brunswick, has said that radiactive seeds used in prostate cancer treatment can migrate to other parts of the body including the lungs. In a procedure called Brachytherapy, tiny metal pellets are implanted in and aroun...

Quicker healing with active bandages

According to researchers, new bandages developed by US researchers take an active part in the healing process. Experiments in mice show that hydrogel bandages speed up healing.They look like thin clear plastic when dry, but expand six times and become pliable when wet.// Unlike regular bandages, which just keep moisture in and germs out, the hydrogel dressings actually penetrate the wound and enh...

Overcoming actively may help in breast cancer

According to new review proposes that having a good coping style helps women to deal positively with breast cancer. There is much debate over whether mental attitude makes a difference in the fight against cancer. Researchers in the US have been looking// at several studies and they conclude that stress, mental outlook and coping style are all relevant to key biological factors like immune functi...

Glaucoma & Ocular Hypertension more likely in patients with refractive errors

A study which appeared in the clinical journal of Ophthalmology concludes that farsightedness appears to be associated with a five-year risk of ocular hypertension, and nearsightedness is associated with a significantly increased prevalence// of glaucoma, in Caucasians. The study was conducted with nearly 5000 participants, aged between 43 to 84, who received baseline assessments of refractive er...

Untreated Scoliosis patients found to lead productive and active lives

Adults who have late-onset idiopathic scoliosis(LIS), a curvature of the spine diagnosed after the age ten, have been found to lead normal, productive lives, contrary to earlier belief that the condition increases mortality rates in general or from cardiac or pulmonary conditions potentially related to the curvature. Researchers from the University of Iowa in a 50-year study have found that adult...

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Slade Refractive Spatula

Description:Smooth, blunt round spatula for manipulations of the corneal flap. Ideal for placement under the flap to expose the stromal interface....
Company:Bausch & Lomb Storz

Slade Refractive Speculum

Description:Designed to provide open approaches of the keratome to the cornea for either the left or right eye. Lightweight wire design adds to the comfort of the instrument when in place....
Company:Bausch & Lomb Storz

OPD-Scan Refractive Power / Corneal Analyzer

Description:Both corneal topography and refractive error data are measured together in a single step to minimize alignment errors. Objective autorefractometry and autokeratometric readings of sphere, cylinder and axis values are simultaneously determined....
Company:NIDEK, Inc.

OPD-Scan II Refractive Power / Corneal Analyzer

Description:The NIDEK OPD-Scan II provides information on corneal topography, wavefront, autorefraction, keratometry and pupillometry in one unit, utilizing state-of-the-art imaging and analysis technology developed specifically to measure normal to highly aberrated eyes. The system offers a variety of data maps to provide information on the total refractive error, wavefront, corneal shape, internal...
Company:NIDEK, Inc.

RCRP high sensitivity C-Reactive Protein (hsCRP)

Description:The High Sensitivity C-Reactive Protein (RCRP) Flex reagent cartridge is an in vitro diagnostic test intended for the quantitative determination of CRP in serum and plasma. This assay is not available for use on the Dimension ES...
Company:Dade Behring, Inc.

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Controlling the Spread of Healthcare Associated Methicillin Resistant Staphylococcus aureus Requires Active Surveillance

Both methicillin sensitive and methicillin resistant Staphylococcus aureus (MSSA, MRSA) can cause invasive and life-threatening infections such as osteomyelitis, septicemia, endocarditis, and pneumonia. Healthcare associated MRSA is of particular clinical importance because it is not only predictably cross resistant to all penicillins and cephalosporins, but is also typically resistant to mu...

Near-Patient Testing: The Advantages of C-Reactive Protein in Hematological Testing

C-reactive protein (CRP) is an acute-phase protein that has long been recognized as a marker of systemic inflammation. CRP measurement can complement a range of diagnostic markers to monitor infection and direct treatment. However, as economic rationalization...

Gentium's Defibrotide Seen as Active in Multiple Myeloma

NEW YORK--(BUSINESS WIRE)--Jun 27, 2007 - Gentium S.p.A. (Nasdaq:GENT) announced the presentation of both clinical and preclinicaldata that support the safety, activity, synergy and potentialmechanism of action of Defibrotide in combination with anticancertherapy in multiple myeloma. Investigators presented both an updatefrom the Company's ongoing Phase I/II clinical trial for patientswith...

In Vitro and In Vivo Data Show Alfacell's Onocanse is Active Against Naive and Chemoresistant Neuroblastoma Cells

Pre-Clinical Results Demonstrate Potential of ONCONASE forTreatment of Neuroblastoma BLOOMFIELD, N.J., June 27, 2007 /PRNewswire-FirstCall/ --Alfacell Corporation today announced that new data show ONCONASE,the company's lead drug candidate, is active against naive andchemoresistant neuroblastoma cells. The pre-clinical in vitro and in vivo data published in CancerLetters (2007; Vo...

Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone

Interim results in a randomized phase II/III clinical trialanticipated later this year SEATTLE, June 26, 2007 /PRNewswire-FirstCall/ -- CellTherapeutics, Inc. (CTI) announced the publication of preclinicalstudies, which demonstrate that treatment with pixantrone (BBR2778) resulted in minimal or no significant cardiotoxicity, whiledoxorubicin and mitoxantrone induced significant cardiac da...

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C-reactive protein

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