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acetylated in Medical Technology

ChemGenex Reports Successful Personalized Dosing of Quinamed at ASCO

...alized dosing and improved drug tolerance. -- Patients with rapid and intermediate acetylator genotypes (who more rapidly metabolize the drug to the acetylated derivative associated with side effects) achieved a maximum tolerated dose (MTD) of 320 mg/m2 of Quinamed weekly, whilst patients with slow acetylator...

ChemGenex Reports Successful Personalized Dosing of Quinamed at ASCO

...sonalized dosing and improved drug tolerance. Patients with rapid and intermediate acetylator genotypes (who more rapidly metabolize the drug to the acetylated derivative associated with side effects) achieved a maximum tolerated dose (MTD) of 320 mg/m2 of Quinamed weekly, whilst patients with slow acetylator...
acetylated in Biological News

A simple feedback resistor switch keeps latent HIV from awakening

...n the cell, Tat deacetylation occurs at a much faster rate than acetylation. Deacetylated (inactive) Tat can take one of two paths--reconversion in to acetylated (active) Tat, or destruction of the protein by cellular machinery. When the appropriate conversion and destruction rates were fed into their model, ac...

Researchers find protein that silences genes

...ss, Ph.D., Washington University professor of chemistry, helped define the precise locations of the acetyl groups that HDA6 can remove, down to which acetylated amino acids are involved. "The bottom line is that HDA6 has very broad specificity. It can remove the acetyl groups from multiple histones and fr...

Novel Enzyme Shows Potential As An Anti-HIV Target

... TAR, and leads to transcription. Tat acetylation dissociates Tat from CyclinT1 and TAR, and transfers Tat to the elongating polymerase complex. Since acetylated Tat can’t recruit CyclinT1 and CDK-9, the authors explain, a new round of transcription requires that new, unacetylated Tats are produced or existing ...
acetylated in Biological Technology

Laser Capture Microdissection (LCM) for the Analysis of Macrophage Gene Expression from Atherosclerotic Lesions

...#9674; RnaseOut RNase inhibitor (Invitrogen, Cat. #10777-019) ◊ acetylated BSA (1g/ml) (Promega, Cat. #R9646A) ◊ 50X 5-carboxy-X-rhodamin...ptase enzyme, 2.5U Taq DNA polymerase, 40U RnaseOut RNase inhibitor,0.625 g acetylated BSA, and 1X 5-carboxy-X-rhodamine internal reference dye (Invitrogen Life T...

Transfection Reagent Selector Kit Handbook

... In the common CAT assay, cell lysates prepared from transfected cells are incubated with 14C-labeled chloramphenicol. The resulting acetylated and unacetylated forms of chloramphenicol are separated by thin-layer chromatography. A qualitative estimate of CAT activity can be ...

Genetic Reporter Systems

...e CAT assay, the CAT-containing lysates of transfected cells are incubated with 14 C-chloramphenicol, which is then acetylated. acetylated and non-acetylated 14 C-chloramphenicol is then separated using thin-layer chromatography and visualized by autoradiography. If necessary,...

Genetic Reporter Systems

...e CAT assay, the CAT-containing lysates of transfected cells are incubated with 14 C-chloramphenicol, which is then acetylated. acetylated and non-acetylated 14 C-chloramphenicol is then separated using thin-layer chromatography and visualized by autoradiography. If necessary,...

Enzyme Immunoassay for Studying Intracellular Levels of cAMP

...itivity is increased to the picomolar range with acetylated cAMP. Cyclic adenosine monophosphate (cAMP) pl... 2 ), standards and prepared samples can be acetylated by treatment with acetic anhydride in t... 1 Picomolar detection is possible for acetylated cAMP, whereas nonacetylated cAMP levels...
acetylated in Biological Products

Rabbit Anti-Human Histone H3, acetyl Polyclonal Antibody, Unconjugated from Lake Placid Biologicals

Description:... Antibody specific for histone H3 acetylated at any of the five N-terminal lysine residues. Rabbit polyclonal serum. Antigen: Synthetic peptide derived from histone H3 N-terminal region, muli...
Company:Lake Placid Biologicals
acetylated in Biological Dictionary

Histone

... Lys 12 acetylation is affected by ... Description: The Acetyl- Histone H3 Antibody Sampler Kit provides a fast and ... Histone H3 is primarily acetylated at Lys9, 14, 18 and 23. Acetylation of H3 at ... The Methyl- Histone H3 Antibody Sampler Kit provides a fast and economical means ... Histone m...
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