A protein that triggers aggressive breast cancer
...B1 into otherwise nonmetastatic breast cancer cells, invasive tumors can be induced in mice; conversely, removing SATB1 from metastatic cells not only abolishes metastasis and tumor growth in mice but also returns cells to their normal appearance in vitro. The researchers have published these and other finding...Receptor for H.pylori Identified in Stomach
...protein as a receptor and that it can increase expression of this receptor in gastric epithelial cells,’ says Peek. ‘Further, absence of this receptor abolishes the inflammatory response that H. pylori induces in infected mice, suggesting that this receptor mediates H. pylori-induced injury in the stomach.’ ...SuperGen to Highlight Oncology Pipeline Data in Multiple Presentations at AACR
... receptor tyrosine 18 kinases of PDGFR and Poster EGFR abolishes Section 20 prostate cancer cell growth in culture and ...How does the opioid system control pain, reward and addictive behavior?
...u-opioid receptors are a key molecular switch triggering brain reward systems and potentially initiating addictive behaviors. The lack of mu-receptors abolishes the analgesic effect of morphine, as well as place-preference activity and physical dependence. This receptor therefore mediates therapeutic (analgesi...Researchers shed light on shrinking of chromosomes
...ue separation defects.” The EMBL researchers found that an enzyme called Aurora kinase is crucially involved in this process. Blocking this enzyme abolishes late condensation of chromosomes. They now hope to uncover the detailed molecular mechanism underlying the late shortening of chromosomes. This could ...Stomach receptor for H. pylori discovered
...protein as a receptor and that it can increase expression of this receptor in gastric epithelial cells," says Peek. "Further, absence of this receptor abolishes the inflammatory response that H. pylori induces in infected mice, suggesting that this receptor mediates H. pylori-induced injury in the stomach." ...Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
...nsor for fat. They show that lingual stimulation of CD36 by fatty acids influences behavioral and digestive physiology. CD36 gene inactivation fully abolishes both the spontaneous preference for fat and the changes in gastrointenstinal secretions mediated by oral delivery of lipids. These findings unveil one...Anti-Glycine Transporter 2, Neuronal (GLYT2) Polyclonal Antibody, Unconjugated from CHEMICON
Description:...with probes to GLYT2 mRNA and to what has been described for glycinergic neurons. Preabsorption of the antiserum with the immunogen peptide completely abolishes the immunostaining....