North & South American researchers find architectural abnormalities in T. cruzi ribosome
A Howard Hughes Medical Institute investigator from Albany, New York, and an HHMI international research scholar from Buenos Aires, Argentina have combined their expertise to identify two peculiar features of the protein-making machinery of the parasite that causes Chagas disease. Their findings could help scientists develop a safe and effective drug for the disease, whose cardiac complications k...Model identifies genes that induce normal skin cells to become abnormal
Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body. The model, developed by Mary J. C. Hendrix and colleagues at Children's Memorial Resea...Jefferson scientists identify gene defect leading to abnormal skin development and cancer
For the rats of Hamelin, it was the Pied Piper's tune. For the destructive sea lamprey of the Great Lakes, it's a chemical attractant, or pheromone, released by lamprey larvae living in streambeds. Following the pheromone trail, adults are drawn to streams favorable for spawning. Researchers have long wanted to identify the pheromone so it could be synthesized and used to control the sea lamprey,...Whole-genome study at Johns Hopkins reveals a new gene associated with abnormal heart rhythm
Using a new genomic strategy that has the power to survey the entire human genome and identify genes with common variants that contribute to complex diseases, researchers at Johns Hopkins, together with scientists from Munich, Germany, and the Framingham Heart Study, U.S.A., have identified a gene that may predispose some people to abnormal heart rhythms that lead to sudden cardiac death, a condi...Chromosomal abnormalities in sperm higher after vasectomy reversal
Men who have had a vasectomy reversed have a very much greater rate of chromosomal abnormalities in their sperm than do normal fertile men, a scientist told the 22nd annual conference of the European Society of Human Reproduction and Embryology in Prague, Czech Republic on Wednesday 21 June 2006. Professor Nares Sukchareon, of the Department of Obstetrics and Gynaecology, Chulalongkorn Universi...Dyslexia due to cerebellum abnormality
Dyslexia a most common learning disorder, affects nearly one in 24 people. People with dyslexia often have great difficulty learning to read, write and spell. Dyslexia was found to have been linked to reduced activity in the cerebellum // of the brain that controls movement, co-ordination and balance, scientists have reported. The research, which was led by Professor Roderick Nicolson...Cleft lip and palate are due to abnormality in brain structure
Clefts of the lip and palate are associated with permutation in brain structure that appear to cause cognitive dysfunction, according to a study recently conducted by researchers at the University of Iowa.// Studying 54 adult men with nonsyndromic facial clefts and 54 male control subjects, the researchers used magnetic resonance imaging to study brain volume and tissue composition. T...Early Detection Of Facial Abnormalities in a Fetus
A cleft happens when the tissues of the face fail to fuse during gestation. It is a repairable birth defect. Cleft lip and palate are the most common facial malformation in newborns. It affects about one in 700 babies.//New research shows fetal magnetic resonance imaging may be more accurate at detecting cleft lip and palate than a sonogram. The detection rates when using sonography for...Finger And Toe abnormalities Related to Maternal Smoking
In the largest study ever conducted on the effects of smoking and incidence of birth defects, it has now been found that maternal smoking is associated with an increased risk of finger and toe abnormalities. // The birth defects could range from polydactly (presence of extra digits in either the arms or feet) to webbed (syndactyly) or missing toes and fingers (adactyly). The researche...Abnormal Brain Structure One Of The Reasons For Depression in Adolescents
A new study shows the reason some adolescents experience depression could be abnormal brain structure.// The study states depressed teenagers tend to have a smaller hippocampus -- the part of the brain responsible for memory, learning, emotion and motivation. Researchers sampled nearly 30 adolescents between ages 13 to 18, half of who had been diagnosed with major depressive disorder.Mag...Data Trol™ Abnormal Control Serum
Description:Data Trol™ Abnormal Control Serum is intended for monitoring the accuracy and precision of commonly used clinical chemistry assays. It is for in vitro diagnostic use only. Provided in a 10 x 5ml lyophilized format, the control offers up to ten days stability at 2 8°C once reconstituted. The control is to be used in accordance with the directions accompanying the assay procedure being u...Genomic Microarray Analysis for Constitutional Abnormalities
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...