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American Biotech Labs(R) Obtains FDA Approval for New Wound Care Gel Product

...tates. The FDA approval letter confirms that abl may market ASAP Wound Dressing Gel "for the topica...hted with the FDA's decision to grant approval for abl to broadly market our ASAP Wound Dressing Gel," sa...uct, and it is a tremendous validation for us that abl products have now received approval from the FDA a...

Scientists uncover indicator that warns leukemia is progressing to more dangerous form

...ociate and co-first author Annelie Abrahamsson. In CML, an enzyme called abl goes in overdrive because of a chromosomal mix-up that occurs during blood cell development. The genes abl and BCR fuse and produce a hybrid BCR-ABL enzyme that drives the excessive ...

Therapeutic DNA Vaccine Company Inovio Biomedical Reports Second Quarter 2008 Financial Results

...widespread protection against such viruses. In addition, we entered into a license agreement with Advanced BioScience Laboratories, Inc. (ABL) so that abl may conduct certain internal research on DNA vaccines delivered using electroporation and to offer electroporation delivery of DNA vaccines as a servi...

MicroRNA controls expression of oncogenes

...lumbres. "This may be particularly beneficial for patients who are resistant to small molecule kinase inhibitors like Gleevec as resistant isoforms of abl and BCR-ABL should contain the target site for miR-203 and are likely to respond to restored miR-203 function." ...

Study finds unique HIV vaccine formula elicits strong immune responses

...t scientific article in which a DNA prime-protein boost combination vaccination method is tested in humans for HIV vaccine development. Scientists at abl and UMMS and their collaborators discovered that this combination approach is highly effective in inducing strong antibody and cell-mediated immune re...

Early Phase II results show bosutinib safe, effective for CML

...the low grade and frequency of side effects is probably a result of the drug's specificity in the proteins that it targets. Bosutinib inhibits SRC and abl proteins but does not affect platelet derived growth factor receptor or C-Kit, two similar kinases that are affected by other CML drugs. CML is cau...

Light Drinkers Tend to Shirk Work Often

...ent drinkers to consume alcohol excessively. As the drinker gets older he/ she reduced the number of sick leaves. Paul Ritchie, spokesperson of abl State Chamber, a business group said that even problem drinkers had showed effects at work because of impairment of their overall perfomance. KOM...

"Miracle" Cancer Drug Gleevec Can be Toxic to the Heart

...e cancerous and multiply. In CML, an enzyme called abl goes in overdrive because of a chromosomal mix-up ...at occurs during blood cell development. The genes abl and BCR become fused and produce a hybrid BCR-ABL ...then we can say, for example, if there are 10 more abl inhibitors coming on line soon, and if the problem...

Mouse Models To Determine The Cause Of Aggressive Leukemia

...al Academy of Sciences. The Bcr-Abl oncogene is formed when a fragment of the Bcr gene from one chromosome switches over to fuse with a portion of the abl gene from the other chromosome. Bcr-Abl encodes for an enzyme called a tyrosine Kinase. This causes the abnormal, uncontrolled multiplication of leuke...

Gene Fusion Test to screen children’s with Acute Lymphoblastic Leukemi

...e which helps to provide more effective and specialised treatment options. The gene test detects gene fusion of gene etv6 with runx1, bcr joining with abl and a gene called mill that can fuse with several different partners. A complete epidemiological study involving more than By looking at more th...

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