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abciximab in Medical News

The Benefits of abciximab with clopidogrel for percutaneous coronary intervention Questioned

Primary findings from the Intracoronary Stenting and Antithrombotic Regimen-Rapid// Early Action for Coronary Treatment Trial (ISAR-REACT) has indicated that abciximab use in patients undergoing percutaneous coronary intervention (PCI) after pretreatment with 600 mg clopidogrel for less than 2 hour...

The future of interventional cardiology presented at TCT 2008

...l Infarction Undergoing Primary Percutaneous Coronary Intervention After Thienopyridine Loading FATA: A Prospective Randomized Trial of Tirofiban and abciximab in Patients with Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention HORIZONS-AMI: A Prospective Randomized Trial of Pa...

TCT update: press conference schedule announced for TCT

...l Infarction Undergoing Primary Percutaneous Coronary Intervention After Thienopyridine Loading FATA: A Prospective Randomized Trial of Tirofiban and abciximab in Patients with Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention HORIZONS-AMI: A Prospective Randomized Trial of Pa...

Anticoagulant Drugs Had Similar Outcomes After Angioplasty

...ients who had angioplasty, the anticoagulant drugs abciximab and tirofiban produced similar outcomes for certai...ear in the April 16 print issue. Treatment with abciximab and implantation of an uncoated stent is a treatme...sn't been clear whether using tirofiban instead of abciximab would provide similar benefits. They added that th...

Comparison of anticoagulants for angioplasty show similar outcomes

...lasty following a heart attack, the anticoagulants abciximab and tirofiban had similar outcomes for some cardia...d in the April 16 issue of JAMA. Infusion with abciximab and implantation of an uncoated-stent is a treatme...whether there may be similar benefits in replacing abciximab with tirofiban, which could have clinical and econ...

New Anti-Clotting Drug Shows Promise in Heart Patients

...he heart in patients undergoing PCI. "Preliminary clinical events did not show any differences, therefore eptifibatide seems a valid alternative to abciximab in patients with primary PCI," said Uwe Zeymer, lead author of the study, which was conducted out of Ludwigshafen, Germany, and funded by GlaxoSmithKl...
abciximab in Medical Technology

BRAVE-3 Questions Value of Abciximab in PCI for Heart Attack

With high-dose clopidogrel, the intravenous anti-platelet drug appears unnecessary CHICAGO, March 30 /PRNewswire/ -- Over the years, interventional cardiologists have made many improvements in percutaneous coronary intervention (PCI) for patients with heart attack...

Drug-Eluting Stents Outperform Bare Stents in Heart Attack

...onale for high-dose tirofiban as an alternative to abciximab in patients with STEMI," said Marco Valgimigli, MD... Patients were randomly assigned to an infusion of abciximab or high-dose tirofiban (25 microgram/kg) and, in a... equivalent in the two groups (83.6 percent in the abciximab group vs. 85.3 percent in the tirofiban group). In...

Positive Aggrastat Results Featured in the Journal of the American College of Cardiology

...RATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus abciximab and Bare Metal Stent In Acute Myocardial Infarction) study were published i...STRATEGY (Multicentre Evaluation of Single High-Dose Bolus Tirofiban Versus abciximab and Sirolimus-Eluting Stent Versus Base Metal Stent in Acute Myocardial Inf...
abciximab in Medical Products

VerifyNow IIb/IIIa Assay

Description:...e instrument uses light transmittance to measure the rate at which this clearing occurs. If the GP IIb/IIIa receptors on the platelet are inhibited by abciximab or eptifibatide, there will be minimal binding of the microbeads with activated platelets, since the GP IIb/IIIa receptor sites are blocked by the dru...
Company:Accumetrics

VerifyNow System

Description:...d a result in minutes. VerifyNow IIb/IIIa, the first assay developed for use on the system is to assess GP IIb/IIIa platelet inhibition in response to abciximab or eptifibatide. VerifyNow Aspirin, the second assay developed for use on the system is to aid in the detection of platelet dysfunction due to aspirin...
Company:Accumetrics
abciximab in Biological News

UCSD researchers create roadmap to integrin activation

... integrin on the cell's surface to get sticky. Direct inhibitors of GPIIb-IIIa binding include antithrombotics such as eptifibatide (Integrelin), abciximab (Reopro), and tirofiban (Aggrestat), drugs that reduce thrombosis, or formation of blood clots, by binding to the receptors and completely blocking th...
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