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Zonisamide in Medical News

Ranbaxy Ties Up With US Co For Mktg Zonisamide Capsules

Pharma major Ranbaxy Laboratories Ltd has entered into a strategic partnership with US-based Invagen Pharmaceuticals Inc for marketing Zonisamide Capsules // , which are used for the treatment of epilepsy, in the US market. Under the agreement products would be developed and submitted for appr...

FDA Adds Suicide Warning to Epilepsy Drugs

...); methosuximide (Celontin); oxcarbazepine (Trileptal); pregabalin (Lyrica); primidone (Mysoline); tiagabine (Gabitril); trimethadione (Tridione), and zonisamide (Zonegran). Some of these drugs are also available as generics. According to the FDA, antiepileptic drugs are used to treat epilepsy, bipolar disor...

FDA Advisers Don't Back 'Black Box' Warning for Epilepsy Drugs

...d as Lyrica), Tiagabine (marketed as Gabitril), Topiramate (marketed as Topamax), Valproate (marketed as Depakote, Depakote ER, Depakene, Depacon) and zonisamide (marketed as Zonegran). Some of these drugs are also available as generics. According to the FDA, antiepileptic drugs are used to treat epilepsy, b...

FDA Advisers Don't Back Epilepsy Drug Warnings

...d as Lyrica), Tiagabine (marketed as Gabitril), Topiramate (marketed as Topamax), Valproate (marketed as Depakote, Depakote ER, Depakene, Depacon) and zonisamide (marketed as Zonegran). Some of these drugs are also available as generics. According to the FDA, antiepileptic drugs are used to treat epilepsy, b...

Epilepsy Drugs Can Cause Suicidal Tendencies, FDA Panel Finds

...d as Lyrica), Tiagabine (marketed as Gabitril), Topiramate (marketed as Topamax), Valproate (marketed as Depakote, Depakote ER, Depakene, Depacon) and zonisamide (marketed as Zonegran). Some of these drugs are also available as generics. According to the FDA, antiepileptic drugs are used to treat epilepsy, b...

FDA Warns Epilepsy Drugs May Raise Suicide Risk

...d as Lyrica), Tiagabine (marketed as Gabitril), Topiramate (marketed as Topamax), Valproate (marketed as Depakote, Depakote ER, Depakene, Depacon) and zonisamide (marketed as Zonegran). Some of these drugs are also available as generics. According to the FDA, antiepileptic drugs are used to treat epilepsy, b...

Pipeline for New Obesity Therapies is Focus of New Report

...s), LH-21 (Instituto de Quimica Medica), Qnexa (phentermine / topiramate; Vivus), Contrave (bupropion / naltrexone; Orexigen), Empatic (bupropion SR + zonisamide SR; Orexigen), Meridia (sibutramine; Abbott), lorcaserin (APD356; Arena), Byetta (exenatide; Amylin/Lilly), exenatide LAR (Lilly/Amylin/Alkermes), exe...
Zonisamide in Medical Technology

Orexigen(R) Therapeutics Presents Data on Its Proprietary Formulation of Naltrexone Sustained Release (SR) Used in Contrave(R)

...ic(TM) Empatic is a fixed dose combination of bupropion SR with our proprietary sustained release formulation of zonisamide. Research indicates that zonisamide inhibits AgRP, a system associated with increasing appetite while bupropion increases metabolism. Based on the strength of these results and the uniqu...

Orexigen(R) Initiates Second Phase IIb Empatic(TM) Trial on Schedule

...o exceed $100 billion annually. Empatic combines zonisamide and bupropion, two existing drugs that have been i... proprietary sustained release (SR) formulation of zonisamide that has demonstrated a better tolerability profil.... The efficacy of Empatic will be compared against zonisamide monotherapy, bupropion monotherapy and placebo. Tr...

OREXIGEN Therapeutics Announces Sustained-Release Formulation of Zonisamide Shows Improved Tolerability When Compared to Immediate Release Formulation

... Orexigen(TM) is evaluating zonisamide SR as a novel component in EMPATIC(TM) Phase IIb o...of zonisamide. In the study, the SR formulation of zonisamide achieved a significant reduction in the incidence ... to an immediate release (IR), legacy formulation. zonisamide SR is a key component in the Company's obesity pro...
Zonisamide in Biological Technology

Novel Once Daily Anti-Epileptic Zebinix(R) Approved in the European Union

...Bial towards bringing to patients such a promising new treatment for epilepsy. Zebinix(R) joins our existing family of anti-epileptics, which includes zonisamide and rufinamide and a new molecule currently entering phase three clinical development studies. When launched, Zebinix(R) will help us to fulfil our Co...

Orexigen(R) Therapeutics Announces Third Quarter 2008 Financial Results

... proprietary sustained release (SR) formulation of zonisamide plus olanzapine. The Phase 2a clinical trial, OZ-1.... 7,425,571 providing broad coverage of the use of zonisamide either alone or in combination with other drugs fo...ued U.S. Patent No. 7,429,580 which broadly covers zonisamide in combination with various marketed atypical anti...

Orexigen(R) Therapeutics Initiates First Clinical Trial of OREX-003 for the Mitigation of Antipsychotic-Associated Weight Gain

... - Two Milestones Reached in zonisamide Patent Portfolio - SAN DIEGO, Oct. 2 /PRNewswire...03, a proprietary sustained release formulation of zonisamide plus olanzapine. The Phase 2a clinical trial, OZ-1.... 7,425,571 providing broad coverage of the use of zonisamide either alone or in combination with other drugs fo...

Orexigen Therapeutics Announces Multiple Data Presentations at The Obesity Society Annual Scientific Meeting

...m Weight Loss from a Dose Optimization Study with zonisamide SR and Bupropion SR" Time: 11:00-11:15 a.m. MT ... Improvements from a Dose Optimization Study with zonisamide SR and Bupropion SR" Time: 12:45-2:45 p.m. MT P...ng of Response from a Dose Optimization Study with zonisamide SR and Bupropion SR" Time: 12:45-2:45 p.m. MT ...

OREXIGEN(R) Therapeutics Receives Notice of Allowance for U.S. Patent Covering the Composition of Matter in OREX-003

...broad coverage for a pharmaceutical composition of zonisamide in combination with a series of marketed atypical ...ed blood glucose associated with olanzapine alone. zonisamide appears to reverse the olanzapine effects on appet...l trials. If issued, this patent will also cover zonisamide in combination with other atypical antipsychotics,...
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(Date:9/30/2014)... New England Journal of Medicine reports positive results ... crizotinib against the subset of lung cancer marked by ... of 50 patients with advanced non-small cell lung cancer ... was 72 percent, with 3 complete responses and 33 ... takes for the disease to resume its growth after ...
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(Date:9/30/2014)... is available in German . ... behavioural response to risky situations such as exposure to ... now found in a long-term study on different populations ... metabolic rate and ambient temperature. High metabolic rates and ... in these scenarios birds were more likely to approach ...
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