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Zometa in Medical News

Novartis files application with FDA for Zometa

Novartis Pharmaceuticals has submitted an application to the Food and Drug Administration, seeking marketing authorization for Zometa in the treatment of bone complications associated with a broad range of tumor types. These include prostate and lung cancer, for which no bisphosphonate therapy is c...

Osteoporosis Drug Seems to Shrink Breast Tumors

...e in pre-menopausal women with early estrogen- or progesterone-positive tumors. In an analysis of slightly more than 200 women, those who received zometa in addition to chemotherapy had better results than those receiving chemotherapy alone. After compensating for variables such as estrogen receptor sta...

Bone Density Predicts Chances of Breast Cancer

...rent aspects of bone health with breast cancer risk. One study presented at the American Society of Clinical Oncology annual meeting in May found that zometa (zoledronic acid), a drug used to treat osteoporosis, lowered the risk of breast cancer recurrence in premenopausal women. And another study rele...

Bone Drug Lowers Risk of Breast Cancer Recurrence

...ustrian researchers also found that women who took zometa (zoledronic acid) had a 30 percent lower risk of t...akes Zometa. Earlier studies had indicated that zometa can reduce bone loss occurring as a result of canc...llow-up of five years, either hormone therapy plus zometa reduced the risk of relapse by 36 percent compared...

Doctors Hopeful for Elizabeth Edwards

...ant professor of medicine at Harvard Medical School. A group of drugs called bisphosphonates are used to strengthen and heal the bone. The drugs, zometa and Aredia, are similar to drugs taken to combat osteoporosis but are more powerful and are given intravenously rather than orally. "Doctors may a...

Zometa [Novartis Drug] For Treatment Of Paget’s Diseas

...of Auckland in New Zealand has found that the drug zometa manufactured by Novartis treats Paget’s disease// ... in The New England Journal of Medicine found that zometa led to six months of improvement in 96 percent of 176 people tested. Though, the drug zometa can produce mild side effects, flu-like symptoms s...

One IV treatment a year rather than a pill a day

...o treat osteoporosis; one also is available as a once-a-week pill. Novartis said it does not know how much the drug is likely to cost. If a version of zometa is approved for use against osteoporosis, it will probably be given another name. ...
Zometa in Medical Technology

Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)

...al cord compression) compared with those receiving zometa (hazard ratio 0.84, 95 percent CI: 0.71-0.98), whi...eatment was not statistically superior compared to zometa (adjusted p=0.06) (secondary endpoint). The time ...greater but not statistically superior compared to zometa (hazard ratio 0.90, 95 percent CI: 0.77-1.04) (sec...

Denosumab Demonstrates Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Breast Cancer Patients With Bone Metastases

...mized, double-blind study comparing denosumab with zometa in the treatment of bone metastases in patients wi...denosumab subcutaneously every four weeks (Q4W) or zometa administered intravenously at a dose of 4 mg singl...nt was to evaluate if denosumab is non-inferior to zometa with respect to the first on-study SRE in patients...

Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports

... - Adding zometa to post-surgery hormone therapy reduced risk of br...hase III data to substantiate anticancer effect of zometa - zometa is the most widely prescribed drug for prevention ...

More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies

...strategy, Femara vs. tamoxifen - Multiple zometa studies at SABCS to affirm anti-cancer activity in...r 13, 2008; 5:00 - 7:00 PM CST). A total of nine zometa abstracts, of which six will show the potential a...imb pain, chest pain and headache. About zometa Zometa(R) (zoledronic acid) is indicated for ...

FDA Broadens US Indication for Once-Yearly Reclast(R) as Only Osteoporosis Treatment Approved for Prevention of Fractures After a Hip Fracture

...onic acid) Injection 4 mg administered every three to four weeks in certain oncologic indications(6). Patients should not take Reclast if they're on zometa as it contains the same ingredient; if they have low blood calcium, kidney problems, or are allergic to Reclast or Zometa; or they're pregnant, plan t...

Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer

... - zometa when added to hormone therapy, following surgery, ...ogram exploring the direct anticancer effect of zometa in breast, lung and prostate cancer EAST HANOVER...e, early-stage breast cancer. The study found that zometa when added to hormone therapy, following surgery, ...

Strength and Innovation of Novartis Oncology Products and Pipeline With Potential to Improve Patient Treatment Demonstrated by More Than 170 Abstracts at ASCO Annual Meeting

...ults from the CALGB trial 79809, of the effects of zometa on bone mineral density in premenopausal women...CDT). Novartis Oncology Products and Compounds zometa is currently used for the prevention of skeletal-r...lectively disrupts existing tumor blood vessels. zometa Safety Information ...

Study Shows Once-Yearly Reclast Better than Risedronate at Increasing Bone Mass in Patients With Osteoporosis Caused by Glucocorticoids

...the brand name Zometa(R) (zoledronic acid) Injection 4 mg for use in certain oncology indications(7). Patients should not take Reclast if they're on zometa as it contains the same ingredient; if they have low blood calcium, kidney problems, or are allergic to Reclast or Zometa; or they're pregnant, plan t...

First Osteoporosis Study in Hip Fracture Patients Finds Once-Yearly Reclast(R) Prevents Additional Fractures and Improves Survival

...lcium) and those who are allergic to zoledronic acid. Reclast contains the same active ingredient found in Zometa. Patients already being treated with zometa should not be treated with Reclast. Reclast should not be used during pregnancy because of potential harm to the fetus. Reclast is not recommended for...

Reclast(R) Receives US FDA Approval as First and Only Once-Yearly Treatment for Women With Postmenopausal Osteoporosis

...lcium) and those who are allergic to zoledronic acid. Reclast contains the same active ingredient found in Zometa. Patients already being treated with zometa should not be treated with Reclast. Reclast should not be used during pregnancy because of potential harm to the fetus. Reclast is not recommended for...
Zometa in Biological Technology

ASCO Results: Oncologists Rank Genentech Number One

...orectal cancer. -- Erbitux (cetuximab) + platinum-based chemotherapy extends overall survival in NSCLC vs. chemotherapy alone. -- zometa (zoledronic acid) increases survival for premenopausal patients who received adjuvant endocrine therapy for early breast cancer. T...

Reclast(R) Receives US FDA Approval as First and Only Once-Yearly Treatment for Women With Postmenopausal Osteoporosis

...lcium) and those who are allergic to zoledronic acid. Reclast contains the same active ingredient found in Zometa. Patients already being treated with zometa should not be treated with Reclast. Reclast should not be used during pregnancy because of potential harm to the fetus. Reclast is not recommended for...
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