Yield

Research on Worms Yields Clues on Aging

Humanityhas been looking for a "Fontaine de Jouvence" forever; a way to slow orstop aging. While its still nowhere to be found, we are makingprogress; in worms. Researchers found that an epilepsy drug used inhumans had the unexpected effect of prolonging the life span of C.Elegans: A class of anti-seizure medications slows the rate of aging inroundwo...

Genome-wide mouse study yields link to human leukemia

Thanks to a handful of very special mice, scientists have discovered a new tumor suppressor gene and a unique chemical signature implicated in the development of human leukemia, findings that open up a "treasure box" of opportunity and possibility, study authors say. Researchers in The Ohio State University Comprehensive Cancer Center bred a type of mouse that develops acute lymphoblastic...

Spider Venom Could Yield Eco-Friendly Insecticides

Biochemist Glenn King is searching for an alternative to chemical pesticides. King's research on insect-specific neurotoxins focuses on one the world's most efficient insect predators -- spiders. The Blue Mountains funnel-web spider (Hadronyche versuta) -- a large Australian spider with a bite that is deadly to humans and insects -- is an ideal source of venom for King's research. The spider "coo...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

Few things about growing older are asinevitable and obvious as “going gray,?yet scientists have been unableto explain the precise cause of this usually unwelcome transformation.In a report posted today on the Web site of the journal Science,researchers from Dana-Farber Cancer Institute and Children’s HospitalBoston say they have found the cellular cause of graying hair whileinvestigating th...

The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures

The Protein Structure Initiative (PSI), a national program aimed at determining the three-dimensional shapes of a wide range of proteins, has now determined more than 1,000 different structures. These structures will shed light on how proteins function in many life processes and could lead to targets for the development of new medicines. The PSI is a 10-year, approximately $600 million pr...

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Yield at Biology Products

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Yeast Protein Production System Features High Yields and One-Step Purification

The ESP system provides high-yield protein production in a eukaryoticorganism Quinn Lu * Bruce Jerpseth * Tim Sanchez * John C. Bauer * AlanGreener Stratagene Cloning Systems, Inc. provides novel opportunities for rapid, inexpensive and high-yield p...

Efficient Cleavage of Fusion Proteins to Yield Native Amino Termini

Recombinant Enterokinase for highly specific digestion of purifiedproteins or proteins in crude extracts Ed Marsh * Johanna Claycomb * ChaoFeng Zheng * Denise Wyborski* John C. Bauer * Joseph A. Sorge * A.K. Bernardino * Peter Vaillancourt Stratagene Cloning Systems, Inc. Stratagene introduces recombinant Enterokinase, an efficient, sitesp...

Trouble-shooting: Low yield

Here are some troubleshooting hints that we have gathered regarding low yield after PCR reactions: <a href="#Option1">Primer annealing temperature is too high...

Combine High Yield, Great Accuracy and the Prevention of Carry-over Contamination by Using the Novel Expand High FidelityPLUS PCR System

Roche Applied Science pioneered the blending of thermostableDNA polymerases and the associated buffersystems. The well-known Expand High Fidelity andExpand Long Template PCR Systems were the first commerciallyavailable blends to provide amplification offragments up t...

ArrayScript RT: Maximize Yields of Full-length cDNA

Ambion scientists have engineered a mutant form of M-MLV reverse transcriptase to improve production of full-length cDNA. This engineered reverse transcriptase, <A href="http://www.ambion.com/catalog/CatNum.php?2048">ArrayScript (patent pending), produces significantly higher yields o...

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Yield at Medicine News

Chemical in Gila monster's saliva yields Alzheimer drug

Alzheimer's is a degenerative brain disease that usually begins gradually, causing a person to forget recent events or familiar tasks. The disease eventually leads// to confusion, personality and behavior changes and impaired judgment. Communication becomes more difficult as the disease progresses, leaving those affected struggling to find words, finish thoughts or follow directions. Even...

A Reduction In Calories Found To Yield More Benefits

A new study reveals that, cutting calories can drastically reduce the risk of clogged arteries, diabetes, high cholesterol and high blood pressure . // High triglyceride levels can lead to atherosclerosis, or clogged arteries, which can be a precursor to heart attack or stroke. Researchers studied two groups of individuals. The first group consumed a restricted-calorie diet. Particip...

Bone Marrow Cells Could Yield A New Lease of Life

Researchers offer intriguing results from a study involving women with leukemia who died after receiving a bone marrow transplant from a male relative.An analysis of the women’s brains shows evidence of the transplanted // cells up to six years after the initial transplant, suggesting some of the bone marrow cells were actually acting as stem cells -- basic cells capable of developing int...

Operating on a Beating Heart Yields Better Results For Blocked Heart Arteries

According to findings of a recent study researchers say bypass surgery on a beating heart might be an effective option for many patients // with blocked heart arteries . Researchers assigned 400 patients with bypass grafts to undergo either on-pump (work of the heart is shifted to a mechanical pump while heart remains still) or off-pump (the heart is still beating) surgery. Results of th...

Christmas trees to yield key Tamiflu ingredient

Biolyse Pharma Corp., a closely held Canadian company that extracts chemicals from plants, plans to use used Christmas trees to extract the chemical for making Tamiflu, the drug that treat bird flu.// The trees contain shikimic acid in their pine, spruce and fir needles, Ontario-based Biolyse said today in a statement. The acid is used in Roche Holding AG's Tamiflu and is mainly extract...

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Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results

Clinical guidelines from the disciplines of cardiology and laboratory and emergency medicine have all emphasized the importance of cardiac markers in diagnosing or ruling out acute myocardial infarction. The measurement of cardiac troponins is especially useful in the large fraction of patients presenting with acute coronary syndrome (ACS) who have...

Vical's Vaxfectin Adjuvant With Needle-free Delivery Enhances DNA Vaccine Performance; Yields Antibody Responses Comparable to Electroporation Without Tolerability Issues

MALAGA, Spain, May 23, 2007 /PRNewswire-FirstCall/ -- VicalIncorporated today announced that in a recently completed animalstudy, a DNA vaccine formulated with the company's patentedVaxfectin(TM) adjuvant and delivered by needle-free injectionyielded significantly higher antibody responses than anunformulated DNA vaccine delivered by needle and syringe. In aseparate animal study, electro...

Lexicon-Genentech Collaboration Yields Potential Therapeutic Targets

Data Presented at Society for Biomolecular Sciences Conference THE WOODLANDS, Texas, April 18, 2007 /PRNewswire-FirstCall/ --Lexicon Genetics Incorporated announced that data was presentedtoday highlighting potential therapeutic targets related to itscollaboration with Genentech, Inc. at the Society for BiomolecularSciences 13th Annual Conference & Exhibition in Montreal,Canada. These...

Study of Drug Therapy for Compulsive Buying Yields a Puzzle, Stanford Researcher Says

STANFORD, Calif.--(BUSINESS WIRE)--Mar 14, 2007 - Researchers atthe Stanford University School of Medicine say they are puzzled byfindings from their new study indicating that an antidepressant,which previously showed promise in treating a behavioral disorderknown as compulsive buying, did not result in a sustained benefitfor the patients who took it. The medication is escitalopram, a com...