New Clues Add 40,000 Years to Age of Human Species
Nearly 40 years after an historic anthropology expedition to Ethiopia's Lake Turkana basin, researchers have uncovered evidence suggesting human bones found at that time are roughly 195,000 years old. The researchers believe the findings may bolster the “Out-of-Africa?hypothesis that suggests we all trace to an ancient line that first evolved in Africa and then displaced other hominids as recent...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
First-of-its-kind analysis published in the Feb. 8 PNAS supports the concept of a basic wiring diagram for all eukaryotes. Researchers in California, Israel, and Germany have compared three distantly related species ?baker's yeast, a worm, and the fruit fly ?and reported that protein "wiring" connections in one species are often conserved in all three. This first-of-its-kind analysis of t...Artifical cornea lets woman blind 20 years see
A severe allergic reaction to a medication robbed Elma Phifer of her vision two decades ago when she was 39. The reaction scarred her corneas and reduced the ability of her eyes to soothe their damaged surfaces by remaining moist. She came to rely upon family and friends to help her do many of the activities people with normal vision sometimes take for granted. Now, twenty years and severa...50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel
Researchers at the University of Chicago have found that a recently discovered biological process known as sumoylation -- until now thought to be active only in the nucleus -- also occurs near the cell's surface where it regulates at least one and possibly many kinds of proteins, providing a novel target for the development of new drugs. The discovery, published in the 8 April 2005 issue o...Navigating an integrated yeast network
Scientists have for the first time mapped multiple complex biological interactions in a yeast cell in a simple graphical form, enhancing our understanding of how the networks of interaction by which components of a cell influence one another. New research published in the Open Access journal Journal of Biology shows that such maps can also reveal cryptic interactions and enable accurate predictio...Baker's yeast (S. cerevisiae) Phosphoglucose isomerase from Sigma-Aldrich
Description:Physical form: Essentially sulfate-free, powder containing carbohydrate and citrate buffer salts Chem comp: Protein ~ 50% (modified Warburg-Christian)...Baker's yeast (S. cerevisiae) S-Acetyl-coenzyme A synthetase from Sigma-Aldrich
Description:Acetate: CoA ligase (AMP forming), Acetate thiokinase Preparation Unit Definition: One unit will form 1.0 mol of S-acetyl coenzyme A from acetate, ATP and coenzyme A per min at pH 7.5 at 37C....Enolase from baker's yeast (S. cerevisiae) from Sigma-Aldrich
Description:Physical form: Lyophilized powder containing Tris buffer salts Physical Form: lyophilized powder...Baker's yeast (S. cerevisiae) Hexokinase and glucose-6-phosphate dehydrogenase from Sigma-Aldrich
Description:Useful for determination of glucose and ATP. -glucose per min at pH 7.6 at 25C....S. cerevisiae yeast Whole Genome from Agilent Technologies
Description:The Yeast Whole Genome ChIP-on-chip Microarray is specifically designed for location analysis of yeast (S. cerevisiae) DNA binding proteins by pairing chromatin immunoprecipitation (ChIP) with Agilent DNA microarrays. This set delivers robust hybridization and reliable binding data with greater true binding events and fewer false positives. In addition, Agilent provides flexibility by offering bo...Epitope-Tagging Vectors for Functional Analysis in Yeast
Stratagene Stratagene has developed a series of epitope-tagging vectors to expressand functionally analyze eukaryotic genes in the budding yeast Saccharomyce...New Yeast Cloning System for Producing Proteins with Native Amino Acid Sequences
Stratagene Cloning Systems, Inc. The ESP LIC cloning and expression system features rapid and high-yieldproduction of recombinant proteins in yeast. This system usesligation-independent cloning (LIC) for efficient and dire...Yeast Protein Production System Features High Yields and One-Step Purification
The ESP system provides high-yield protein production in a eukaryoticorganism Quinn Lu * Bruce Jerpseth * Tim Sanchez * John C. Bauer * AlanGreener Stratagene Cloning Systems, Inc. provides novel opportunities for rapid, inexpensive and high-yield p...Biotech industry reaches midpoint in 50-year maturation cycle
An interesting article in ) on March 1 states unequivocally that most industry cycles run about 50 years until they mature. If this...Electroporation of Yeast Artificial Chromosomes
Maren Bell and Robert Mortimer, Human Genome Center, Divisionof Cell and Molecular Biology, Lawrence Berkeley Laboratory,Berkeley, California 94720 Transformation of yeast with yeast artificial chromosomes (YACs) has traditionally been performed by a PEG-spheroplast procedure. However, the...Diagnosis of Alzheimer's years before clinical signs emerge
Brain researchers are developing tests that can identify the beginnings of Alzheimers years before the first clinical signs of the disease emerge. The researchers, who presented their results on 14 // November at the annual meeting of the Society for Neuroscience in Washington DC, say the tests allowed them to single out people who went on to develop the condition. If those results ar...New Test Can Detect Breast Cancer 8 Years Earlier
There is a new test some doctors say could change the way we treat breast cancer. The new Halo Pap Test for the breast is now available to help doctors identify breast disease // up to eight years earlier than a lesion might be found on a mammogram. Breast pap patient Amy Rhoades is taking a screening test that could potentially predict her risk for breast cancer up to eight years in ad...Fraudulent Dentist Jailed For Three Years
A dentist who was accused of defrauding the NHS of more than £600,000 has been sentenced to three years in jail. 45-year-old Michael Semeniuk of Willerby, near Hull carried on// this fraud for more than six years during which he filed around 3,500 cases of false claims for payment. The Hull Crown Court was told that the claims were filed for treating dead patients or for work, which was...One IV treatment a year rather than a pill a day
One IV treatment a year may prevent osteoporosis. The research involves a drug called zoledronic acid, which is approved for use in cancer patients to treat a condition in which calcium seeps from the bones. The drug was found to slow the rate of bone less and increase bone density, and the effect persisted for at least a year after treatment, long after the medication had disappeared fro...Test tube babies, 25 years later
Considered a pioneering fertility treatment 25 years ago, IVF has now been responsible for an estimated 114,000 babies born in the United States alone, according to the American Society for Reproductive Medicine. IVF is a procedure that involves retrieving the eggs from the mother and mixing them in the lab with sperm from the father. The resulting embryo is then placed back into the moth...DryEase® Mini-Gel Drying Frame
Description:The DryEase Mini-Gel Drying System is a simple easy-to-use kit which dries gels evenly using passive evaporation. The kit allows gels to be assembled on a base between two open frames so both outer surfaces of the gels are exposed to air. Consequently drying is even and cracking is minimized. The proprietary Gel-Dry™ Drying Solution modulates the rate of water release to ensure crack-free g...Antimicrobial Susceptibility-Yeast Susceptibility
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...