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Insight into DNA's 'weakest links' may yield clues to cancer biology

The chromosomes of mammals, including humans, contain regions that are particularly prone to breaking under conditions of stress and in cancer. Now, new research by geneticists at Duke University Medical Center finds that yeast cells also contain such weak links in DNA and begins to reveal the molecular characteristics of these links that might help to explain them. The findings, publishe...

Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage

The immune system is a marvel of versatility, creating a variety of cells that develop in different ways to protect the body. To carry out these tasks, immune cells follow a career path that forks at various points in their development. In a report in the May 2005 issue of Immunity, Fox Chase Cancer Center scientists led by immunologists David L. Wiest, Ph.D. and Dietmar J. Kappes, Ph.D., show th...

Depression gene may weaken mood-regulating circuit

A brain scan study suggests that a suspect gene may increase susceptibility to anxiety and depression* by weakening a circuit for processing negative emotion. People with the depression-linked gene variant showed less gray matter and weaker connections in the mood-regulating circuit. How well the circuit was connected accounted for nearly 30 percent of their anxious temperament, researchers at th...

MicroRNA tweaks protein that controls early heart development

Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA ?a chemical cousin of DNA ?helps fine tune the production of a key protein involved in the early development of heart muscle. The findings, available in the online edition of the journal Nature, may aid scientists in their understanding of how a progenitor cell, or stem cell, decides...

Aggression-related gene weakens brain's impulse control circuits

A version of a gene previously linked to impulsive violence appears to weaken brain circuits that regulate impulses, emotional memory and thinking in humans, researchers at the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) have found. Brain scans revealed that people with this version ?especially males ?tended to have relatively smaller emotion-related brain str...

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Professors want to tweak, not overhaul, patent law

, the landmark law that gave universities...

Is Wisconsin's economy stronger, weaker, or just changing?

"Plant buyouts hit home: GM, Delphi workers take buyouts" "About 260 at Briggs & Stratton to retire to secure health deal" "Walworth County loses bid as Honda picks Indiana site for plant." But if you read these news stories,...

California group says ruling weakens WARF's stem cell patent

regarding its stem cell patent, but a spokesman for the Wisconsin foundation said its recent $1 million jury reward in the Xenon Pharmaceuticals case demonstrates its ability t...

Though Weakening, Biotech IPO Market Still Viable, Burril & Co. Says

These lists allow me to arrange information into tidy boxes in some meaningful order for others (or at least to make better sense out of the information for myself). While my list propensity didnt come from David Letterman, his show enlightened me about how li...

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Old are not weak

According to a study, loss of muscle is not an inevitable consequence of ageing. As you age, your body cannot make new muscle protein fast enough and thereby lose muscle strength. Meanwhile a new study from the University of California shows that muscle protein is made as quickly as it is broken down in men over 70. In fact there is no difference in muscle protein turnover between older m...

Novel Biological Pacemaker Under Construction for Weak Hearts

Johns Hopkins scientists have developed a natural or rather biological pacemaker by fusing connective tissue cells of guinea pigs with heart muscle cells. The newly developed pacemaker can fire on it’s own and regulate the rhythm // of the heart in a more physiological way. Two sets of tiny electroactive 'pacing cells' (SA node) give rise to the heart’s normal rhythm by stimulating oth...

FDA's control is inherently weak

The Food and Drug Administration has few details about the dramatic rise in overseas drug testing and reforms are needed to protect both foreign patients taking experimental medicines and Americans who buy products based on their results. The number of pharmaceutical researchers working outside the United States who voluntarily report their experiments to the FDA increased 16-fold from...

Ibuprofen weakens aspirin's effect

Many heart patients regularly take aspirin because it thins the blood and prevents the clots that cause heart attacks. Ibuprofen belongs to a widely used class of pain relievers known as nonsteroidal anti-inflammatory drugs.// Ibuprofen is widely used for arthritis and other aches and pains. The popular pain reliever ibuprofen blocks the heart-protecting effects of aspirin, according to a...

Severe stress weakens immunity

People undergoing oppressive stress have measurable anomalies in their immune system that make them more vulnerable to illness. It's widely believed that stress may impair health, although the underlying// mechanisms are not clear. Now researchers at Washington University in the US reveal that exposure to chronic stress has a specific effect on immunity. When an inflammatory response...

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Mackool Cataract Support System (CSS) for Weak Zonule

Description:The Mackool Cataract Support System (CSS) provides absolutely reliable support to the lens capsule and enclosed nucleus, thereby permitting routine phacoemulsification regardless of zonular status. Insertion is extremely easy (similar to disposable iris retractors), and removal is accomplished in seconds. Unlike and endocapsular rin...
Company:IMPEX Surgical, Inc.

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