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Vitro at Biology News

Human Eggs Can Develop From Ovarian Surface Cells In Vitro

Research has shown for the first time that human eggs may develop directly from cultured ovarian surface epithelium (OSE) cells derived from adult human ovaries. Oocytes derived from the culture of OSE cells developed in vitro into mature eggs suitable for fertilization and development into an embryo. These findings, published today in the Open Access journal Reproductive Biology and Endocrinolog...

Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005

Scientists in Belgium have discovered how to clone human embryos from eggs that have been matured in the laboratory. Their discovery should make it easier for scientists to create embryonic stem cell lines from cloned embryos and develop them to provide eggs and sperm for infertile couples, the 21st annual conference of the European Society of Human Reproduction and Embryology heard today (Monday...

'Accelerated evolution' converts RNA enzyme to DNA enzyme in vitro

This "evolutionary conversion" provides a modern-day snapshot of how life as we understand it may have first evolved out of the earliest primordial mix of RNA-like molecules-sometimes referred to as the "pre-RNA world"-into a more complex form of RNA-based life (or the "RNA world") and eventually to cellular life based on DNA and proteins. Nucleic acids are large complex molecules that store and...

Cyclosporine inhibits hepatitis C virus in vitro

Liver transplant patients with hepatitis C virus (HCV) achieved significantly better long-term viral response when taking the immunosuppressive agent Cyclosporine along with interferon-ribavirin combination therapy. Cyclosporine also showed efficacy against Hepatitis C virus in vitro. The results of this study appear in the January 2006 issue of Liver Transplantation, the official journal...
Vitro at Biology Products

Blasticidin S HCl from Invitrogen

Description:Blasticidin is a nucleoside antibiotic from Streptomyces griseochromogenes. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to blasticidin is conferred by the products of the bsd gene product from Aspergillus terreus....
Company:Invitrogen

EBY100 S. cerevisiae Strain from Invitrogen

Description:The pYD1 Yeast Display Vector is specifically designed to target and display recombinant proteins on the surface of Saccharomyces cerevisiae. Displayed proteins can be analyzed for their ability to interact with known or putative ligands. pYD1 uses the a-agglutinin yeast adhesion receptor which consists of two domains Aga1 and Aga2 to display recombinant protein on the surface of S. cerevisiae. T...
Company:Invitrogen

Anti-JIP 1 / 2 (SH3) Polyclonal Antibody, Unconjugated, Clone ZMD.177 from Invitrogen

Description:The JNK (c-Jun NH2-terminal kinase) signal transduction cascade is one of three identified MAP kinase pathways in mammals. JNK pathway activation occurs in response to environmental stress, is associated with the nuclear accumulation of JNK itself, and is implicated in the immune response, cellular proliferation, oncogenic transformation, morphogenesis, and apoptosis.JIP1 (JNK-interacting protein...
Company:Invitrogen

SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. One mL stains 100 minigels. A 500 µL unit size (S-7564) and a special packaging (S-7586) are available....
Company:Molecular Probes (Invitrogen)

SYBR Green II RNA gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)

Description:is a sensitive nucleic acid gel stain that has bright fluorescence when bound to RNA and low background in gels, making it ideal for use with either formaldehyde/agarose or polyacrylamide gels using laser scanners or standard UV transilluminators. 500 µL stains 50 minigels. A 1 mL unit size (S-7568) and a special packaging (S-7586) are available....
Company:Molecular Probes (Invitrogen)

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Vitro at Biology Technology

GeneChip Sample Cleanup Module for cleanup of cDNA and in vitro transcribed cRNA

A crucial step in gene expression analysis is target labeling. To improve the critical steps in the target-labeling process, QIAGEN has developed the GeneChip Sample Cleanup Module specifically for use with Affymetrix GeneChip expression arrays. The GeneChip Sample Cleanup Module was developed as part of an on...

In-Vitro Metabolism Studies Using Data-Dependent LC/MSn

P.R. Tiller, Thermo Finnigan W.H. Schaefer, D.M. Murphy, SmithKline Beecham Pharmaceuticals Metabolite Characterization The data presented here can be acquired using the Thermo Finnigan LCQ Series of ion trap mass spectrometers....

RNArticles: RNA Amplification Used to Develop a New In Vitro HCMV Assay

Gene arrays can be used to simultaneously measure the expression levels of thousands of genes in a single experiment. One limitation of this technology is that large amounts of RNA may be required for each array hybridization experiment -- typically 10 g of total RNA. This becomes problematic when working with limited sampl...

RNAClean - RNA & cDNA in vitro Reaction Purification

Agencourts RNAClean kit provides a simple, flexible and highly reproducible method for purifying nucleic acid products generated in common enzymatic RT and IVT reactions such as cDNA and cRNA. The kit is formatted for microarray gene expression analysis experiments and is easily performed in manual or automated formats. RNAClean eliminates...

High Throughput siRNA Delivery In Vitro: From Cell Lines to Primary Cells

A variety of siRNA applications, including siRNA library screening, require the efficient delivery of hundreds to thousands of siRNAs to cells. Most published siRNA studies describe performing transfections in 6 well and 24 well formats. Ambion has developed two reagents, siPORT...

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Vitro at Biology Dictionary

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Vitro at Medicine News

Functional Taste Cells Cultured In Vitro

Nancy Rawson, PhD, a cellular biologist who is the principle investigator said that the new technique of in vitro culturing of taste cells would help them to discover molecules that can enhance or block different kinds of tastes.// Researchers from the Monell Chemical Senses Center have succeeded in growing mature taste receptor cells outside the body. They have also been successful in ke...

Alcoholism Drug Vivitrol Approved By FDA

The federal agency announced through its web site, on 14th April, that the US Food and Drug Administration has approved the drug Vivitrol (TM), for the treatment of alcoholism. // According to foodconsumer.org, Vivitrol was developed by Alkermes, Inc., which will be responsible for the manufacturing of the drug while Cephalon will take on the marketing and sales for the drug under an...

Scientists Create Live Birth Using Artificial Sperms Produced In Vitro

Scientists hoping to find a solution for male infertility have in an experiment for the first time ever, produced and used artificial sperms to create a living being// (mice). Professor Karim Nayernia and team, from Georg-August University, Gottingen, Germany, have created artificial sperm in a lab from the mouse embryonic stem cells. Professor Nayernia, who has now moved to the Newc...

China's Neusoft and Trivitron Plan to Set up Medical Equipments Unit

The Neusoft group, China's largest medical technology solutions provider with a turnover of $700 million, is planning a joint venture with the Chennai-based //Trivitron group to set up a medical equipment manufacturing unit, possibly in Bangalore. "The potential joint venture will earmark an initial investment of $5 million and will gradually scale it up to $25 million over a period of...

HPV Could Hamper Success Rates of In Vitro Fertilization

A new study has indicated that the Human papillomavirus (HPV) could upset promising outcomes associated with In Vitro Fertilization (IVF). Human papillomavirus is// associated with the growth of warts, spread by the environment or by mere skin-to-skin contact. Researchers from New York Hospital-Cornell Medical Center discovered that women who tested positive for HPV had only a 50% ch...

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Vitro at Medicine Products

Vitros 950 Chemistry System

Description:The Vitros 950 provides power and efficiency to meet the needs of high volume testing facilities. With fast throughput of up to 900 results per hour, the Vitros 950 can store and perform the full complement of Vitros chemistry assays on a continuous basis....
Company:Ortho-Clinical Diagnostics

Vitros 250 Chemistry System

Description:The Vitros 250 is a flexible system that can meet requirements in multiple environments small hospitals, backup in large hospitals, clinics and satellite locations. The Vitros 250 also features on-board dilution, and can be automated or placed in a workcell....
Company:Ortho-Clinical Diagnostics

Vitros DT60 II Chemistry System

Description:When you need quick, accurate, convenient, and cost-effective diagnostic test results, rely on the compact VITROS DT60 II Chemistry System. This easy-to-use bench top system fits your point-of-care and back-up laboratory testing requirements. And it helps you meet your overall laboratory needs -- better patient outcomes, reduced overall costs, and improved patient satisfaction. The VITROS...
Company:Ortho-Clinical Diagnostics

Vitros Eci

Description:The Vitros ECi brings true automation and continuous random access capabilities to immunodiagnostic testing. Highly sensitive assays for thyroid, anemia, cardiac, reproductive, endocrinology, oncology and bone metabolism testing are currently available, with infectious disease assays under development. The Vitros ECi can simultaneously process 60 accessible samples for a throughput of 90 patient...
Company:Ortho-Clinical Diagnostics

VITROS® Anti-HBs Assay

Description:The VITROS Anti-HBs assay is the firstdiagnostic hepatitis assay approved by theU.S. Food and Drug Administration capableof being run in a random access format onthe VITROS ECi ImmunodiagnosticSystem with Intellicheck. So now youcan run a hepatitis test at any time, inany order.The VITROS Anti-HBs assay is intended forthe qualitative in vitro determination of totalantibody to hepatitis...
Company:Ortho-Clinical Diagnostics

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Vitro at Medicine Technology

In Vitro and In Vivo Data Show Alfacell's Onocanse is Active Against Naive and Chemoresistant Neuroblastoma Cells

Pre-Clinical Results Demonstrate Potential of ONCONASE forTreatment of Neuroblastoma BLOOMFIELD, N.J., June 27, 2007 /PRNewswire-FirstCall/ --Alfacell Corporation today announced that new data show ONCONASE,the company's lead drug candidate, is active against naive andchemoresistant neuroblastoma cells. The pre-clinical in vitro and in vivo data published in CancerLetters (2007; Vo...

Samaritan Announces Positive Data in Nonclinical (IND) In-Vitro Studies for Promising Alzheimer's Drug

Samaritan Announces Positive Data in Nonclinical (IND) In- VitroStudies for Promising Alzheimer's Drug LAS VEGAS, May 3, 2007 (PRIME NEWSWIRE) -- SamaritanPharmaceuticals Inc. (AMEX:LIV), a developer of innovative drugs,is pleased to announce positive results were attained with itslate-stage preclinical/nonclinical testing of Caprospinol (SP-233),with well recognized in-vitro models....

terna Zentaris Discloses First In Vitro Data for its PI3K Inhibitors at the AACR Annual Meeting in Los Angeles

Second generationpyridopyrazine-urea derivative compound series show highlyselective PI3K-inhibition which could be valuable for cancertreatment QUBEC CITY, Canada, April16, 2007 terna Zentaris Inc. (TSX: AEZ; Nasdaq:AEZS), a global, pure play biopharmaceutical company...

AEterna Zentaris Discloses First In Vitro Data for its PI3K Inhibitors at the AACR Annual Meeting in Los Angeles

Second generation pyridopyrazine-urea derivative compound seriesshow highly selective PI3K-inhibition which could be valuable forcancer treatment QUEBEC, April 16, 2007 /PRNewswire-FirstCall/ - AEterna ZentarisInc. , a global, pure play biopharmaceutical company focused onendocrine therapy and oncology, today presented an abstractoutlining first in vitro data on its pyridopyrazine derivat...

AEterna Zentaris To Present First In Vitro Data for PI3K Inhibitors and In Vivo Results for a GHRH Antagonist at the AACR Annual Meeting in Los Angeles

QUEBEC CITY, April 13, 2007 /PRNewswire-FirstCall/ - AEternaZentaris Inc. , a global, pure play biopharmaceutical companyfocused on endocrine therapy and oncology, today announced that itwill present two abstracts outlining first in vitro data on itsPI3K inhibitors as well as in vivo data on its GHRH antagonist,JMR-132, which both may potentially provide new therapeuticapproaches for the...

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