Team led by Scripps Scientists increases understanding of two types of blindness
...it the unique characteristics of Mller glia to develop a better form of gene therapy delivery. The researchers were able to safely inject into the vitreous cavity, rather than the retina itself, viral particles loaded with the genetic sequence that codes for a protein called neurotrophin 4, which promotes...From outer space to the eye clinic: New cataract early detection technique
...ists in looking at long-term lens changes due to aging, smoking, diabetes, LASIK surgery, eye drops for treating glaucoma, and surgical removal of the vitreous gel within the eye, a procedure known to cause cataracts within six months to one year. It may also help in the early diagnosis of Alzheimer's disease...Ophthalmology highlights Jan. 2009
...levels of four inflammatory factors and one anti-inflammatory factor in the vitreous gel, which fills the eye between the lens and the retina, in 53 patients wi...atory factors were significantly higher and PEDF significantly lower in the vitreous of in patients with DME compared with the two other patient groups. VEGF an...Conference report highlights new research into drug delivery to treat eye disease
...ometers into the cornea or sclera to deliver drugs. A safer alternative to direct intravitreous injections might be transscleral delivery into the vitreous using subconjunctival injections, said Michael Robinson, MD, adding that researchers needed a clear understanding of the dynamic barriers for the tech...Pilot Study to Assess Safety and Efficacy of Medidur(TM) FA in AMD Patients Treated With Lucentis(R)
...(DME) in the FAME Phase III clinical trial. Using a proprietary 25 gauge injector system, an eye care professional injects the Medidur insert into the vitreous through a minimally invasive procedure in an outpatient setting. About Alimera Sciences Inc. Alimera Sciences Inc. is singularly focused on the de...Photo: KFC Colonel Original and Look-a-Like Share Eye Treatment Success Story
... back," said Baxley. "The Colonel" had extensive vitreous cloudiness in both eyes. "I could no longer safely...in the film. "We developed the term Degenerative vitreous Syndrome, or DVS," said Dr. Morris, "to describe extensive vitreous cloudiness, and we defined it as the spontaneous o...DSMB Supports Continuation of the Phase 3 Clinical Trial of Medidur(TM) FA for the Treatment of DME
...treatment for diabetic macular edema (DME). Using a proprietary 25 gauge injector system, an eye care professional injects the Medidur insert into the vitreous through a minimally invasive procedure in an outpatient setting. Currently, there are no FDA approved drug treatments for DME. "We are very pleased t...Vision Loss Can Be Prevented in People With Diabetes
...ss. Blood sugar fluctuations can also promote growth of new, fragile blood vessels on the retina, which can easily break and leak blood into the vitreous (the clear, jelly-like substance that fills the center of the eye). This can blur vision and lead to permanent blindness. In its earliest stages ...Eye could reveal serious health disorder
..., reported online edition of Daily Mail. The new eye test by an upgraded 'ophthalmoscope' a traditional instrument used to examine the retina and vitreous takes only three minutes and can help doctors diagnose life-threatening disease, it said. The eye is very much an early warning post since its bl...Tiny Cup Attached to Eye Improves Drug Delivery For Retinal Diseases
...re effective method for the sustained delivery of medicines for retinal and vitreous diseases, according to a new report by A. Linn Murphree, M.D, director of t...d macular degeneration, require frequent out-patient visits and can lead to vitreous hemorrhage and retinal detachment. Eye drops are also generally ineffective...ThromboGenics' Microplasmin Phase III Program Progressing According to Schedule
...III microplasmin trials is the non-surgical treatment of focal vitreomacular adhesion. Focal vitreomacular adhesion is a condition in which the vitreous gel, in the center of the eye, has an abnormally strong adhesion to the retina at the back of the eye. These adhesions can cause vessel and retinal di...ESBATech's Antibody Fragment Enters Phase Ib/IIa in Ophthalmology
... as eye drops to both anterior and posterior segment of the eye. In particular, topical administration of ESBA105 results in significant levels in the vitreous body which is of significant importance for many ocular diseases. In addition, only very low systemic exposure is observed, adding to the excellent sa...NeoVista Unveils 18-month Data on Novel Wet AMD Therapy at Retina Society Meeting
... Most of the limited number of adverse events were related to the vitrectomy procedure (retinal tear, retinal detachment, subretinal hemorrhage, and vitreous hemorrhage), rather than the epiretinal brachytherapy. To date, no instances of radiation toxicity have been reported by the Doheny reading center. ...ESBATech's Lead Antibody Fragment Enters Clinical Development for Ophthalmic Indications
...ack) segments of the eye, the latter including the vitreous humor, retina and choroid. Peter Lichtlen, M.D.,...apeutic levels are reached in both the aqueous and vitreous humor after only a couple of hours following initi...d half-life of 25 hours in the vitreous. Thus, the vitreous acts as a natural depot compartment for ESBA105, a...NeoVista Presents One Year Data on Novel Wet AMD Therapy at Macula Society
...stin throughout the year. Most adverse events were related to the vitrectomy procedure (retinal tear, retinal detachment, subretinal hemorrhage, and vitreous hemorrhage). No events related to radiation toxicity have been reported to date. Jeffrey S. Heier, MD, a retinal specialist, partner at Ophthalmic C...Maumenee Vitreous Aspirating Cannula
Description: Maumenee vitreous aspirating cannula, 18 gauge....Healon Vitreous Aspirating Cannula
Description: Healon vitreous aspirating cannula, 21 gauge....Wilson Vitreous Foreign Body Forceps
Description: Three 2 mm prongs with 0.1 mm angled tips. 20 gauge (.89 mm) diameter shaft. Lightweight Wilson style squeeze handle with dull finish. Most popular size or model....Maumenee-Barraquer Vitreous Sweep Spatula - Left
Description: 10 mm angled tip with indentation on side and gently curved blade. Round knurled handle with polished finish. Indentation: left side....Maumenee-Barraquer Vitreous Sweep Spatula - Right
Description: 10 mm angled tip with indentation on side and gently curved blade. Round knurled handle with polished finish. Indentation: right side....Researchers describe protease inhibitor that may aid in diabetic retinopathy treatment
... blood vessels grow along the retina. However, these fragile vessels can hemorrhage easily, and blood may leak into the retina and the clear, gel-like vitreous that fills inside of the eye. Unless quickly treated, this can result in spots, floaters, flashes, blurred vision, vision loss, and even temporary bli...American Chemical Societys Weekly PressPac -- May 7, 2008
... lead to new insights into disease mechanisms and new treatments, the article states. MTS ARTICLE #1 FOR IMMEDIATE RELEASE Characterization of the vitreous Proteome in Diabetes without Diabetic Retinopathy and Diabetes with Proliferative Diabetic Retinopathy DOWNLOAD FULL TEXT ARTICLE http://dx.doi.or...Zooming in on the protein-conducting channel
...chers immersed the PCC-containing complex in water and then abruptly froze it in supercold liquid ethane. The rapid freezing imprisoned the complex in vitreous ice, a glassy non-crystalline form of ice, thus preserving its native structure. Using an electron microscope with a low-intensity beam to avoid damag...ThromboGenics NV: Business Update
... these Phase III microplasmin trials is the non-surgical treatment of focal vitreomacular adhesion. Vitreomacular adhesion is a condition in which the vitreous has an abnormally strong adhesion to the retina at the back of the eye. These adhesions can cause vessel and retinal distortion which results in deter...First oral uveitis drug reduces both inflammation and recurrence in potentially blinding eye disease
...kg BID dose fully met the primary endpoint of superiority to placebo at both weeks 16 (p=0.008) and week 24 (p=0.027) for mean change from baseline in vitreous haze, a validated measure of inflammation of the posterior segment of the eye. The magnitude of the effect was >1 step change from baseline, demonstra...ThromboGenics N.V.: Business Update
... program was in part based on the positive results from the Phase IIb MIVI III trial announced in late June. The MIVI III (MIVI III - Microplasmin for vitreous Injection) trial showed that the most effective dose of microplasmin studied (125 (micro)g) was able to resolve the underlying disease in approximatel...Beaumont Doctor's Invention Improves Cataract Surgery Outcomes
...illion people worldwide have cataract surgery. Elements of the eye, such as vitreous body or the lens capsule, can shift as the cataract is removed. vitreous body, a clear gel that fills the eyeball behind the lens, can move into the...ThromboGenics N.V. - Business Update
... eye diseases such as retinal detachment, diabetic vitreous hemorrhage and macular hole. It is estimated that ...ldwide. Vitrectomy is used to induce a posterior vitreous detachment (PVD), which involves removing the vitreous from the eye. As microplasmin is a proteolytic enz...ThromboGenics Announces 2007 Full Year Results
...ones with microplasmin for ophthalmic indications. Initiation of a Phase IIb clinical trial of microplasmin in vitrectomy (MIVI III - Microplasmin for vitreous Injection) in the United States, as well as the initiation of two Phase IIa clinical trials of microplasmin in Europe, for vitreomacular traction and ...ThromboGenics - Business Update and Interim Results for the Seven Month Period Ending 30 June 2007
...plasmin in vitrectomy (MIVI III - Microplasmin for vitreous Injection) in the United States, as well as the in...ts undergoing vitrectomy (surgery that removes the vitreous to induce posterior vitreous detachment, or PVD). Vitrectomy is an increasingly...