Viral DNA sequence a possible trigger for breast cancer
A small sequence of DNA in the envelope (Env) protein of a mouse breast tumor virus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et al. in the February 7 issue of The Journal of Experimental Medicine. The ability of this motif to transform cells single-handedly suggests that viral infection may be an important and previously unrecognized trigger for bre...New binding target for oncogenic viral protein
The DNA tumor virus simian virus 40 produces the Large T antigen which inactivates two of the cell's most important cancer-preventing proteins, p53 and pRb. In a study published in the Journal of Biological Chemistry, researchers at the Fred Hutchinson Cancer Research Center report the discovery of an additional target for T antigen--a protein called Fbw7. The Fbw7 gene is located in a ch...Novel antiviral technology inhibits RSV infection in mice
A novel antiviral treatment combiningnanoparticle and gene silencing technologies thwarts attacks ofrespiratory syncytial virus (RSV) -- a virus associated with severebronchitis and asthma, an animal study by University of South Floridaresearchers found. The study was reported in the January 2005 issue ofthe journal Nature Medicine.RSV infects lung cells and can be life-threatening in very...NYU Study Reveals How Brain's Immune System Fights Viral Encephalitis
New York University biologists have uncovered how the innate immune system in mice's brains fights viral infection of neurons. The findings, published as the cover study in the latest issue of Virology, show that proteins in neurons fight the virus at multiple stages--by preventing the formation of viral RNA and proteins, and blocking the virus' release, which could infect other cells in the brai...NYU study reveals how brain's immune system fights viral encephalitis
New York University biologists have uncovered how the innate immune system in mice's brains fights viral infection of neurons. The findings, published as the cover study in the latest issue of Virology, show that proteins in neurons fight the virus at multiple stages--by preventing the formation of viral RNA and proteins, and blocking the virus' release, which could infect other cells in the brai...ViraPower Lentiviral Packaging Mix from Invitrogen
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Retroviral libraries with high-titer efficiency and larger insertpotential ViraPort Retroviral cDNA Expression Libraries Katherine Felts Kim Zaharee Latha Sundar JamieLimjoco Anna Waesche Peter Vaillancourt Stratagene We introduce a set of human cDNA expression li...Versatile Reporter Vectors for Monitoring Viral Transduction
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Faster, easier screening for difficult transfections when using thecomplete control kit Stratagene We describe the vector pFB-ERV, an MMLV-based replication-defectiveretroviral vector for delivery of the ecdysone receptor proteins RXR and VgEcR.In stable cell lines infected with an estima...High-Titer Retroviral Vectors for Gene Delivery
High-TiterRetroviral Vectors for Gene Delivery Stratagene The high-titer retroviral vectors pFB and pFB-Neo can be used with anyMoloney Murine L...FDA panel refuses anti-viral cold remedy
An advisory panel voted unanimously against recommending FDA approval for the first antiviral cold medication, dashing company hopes of having the drug on the market in time for this year's cold season. The FDA's Antiviral Drugs Advisory Committee cited safety concerns of the drug pleconaril, which it said were not balanced by the drug's "modest" benefits in treating an illness that is not life-t...New oral antiviral treatment of cold sores approved
A supplemental new drug application (sNDA) for Valtrex (valacyclovir HCl) caplets has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of cold sores in healthy adults. This was announced by GlaxoSmithKline which also added that this new application for Valtrex// makes it the first one-day, oral antiviral medication proven to shorten the duration of a cold sore outbre...Viral encephalitis can cause more damage than already known
A study of patients with viral encephalitis by researchers at the ClevelandClinic, Ohio has revealed that the condition could cause seriouys movementproblems. The investigators studied a group of patients with the condition, fiveof whom had West Nile virus. They found that 11 of the victims were admitted toneurological intensive care, while four developed severe movement disorders liket...Gene-Nanoparticle Gene Transfer Is Better Than Viral Vector Transfer System
Nanoparticles can be used in gene therapy to transfer therapeutic genes in to brain cells //and helps in studying genetic mechanism of brain diseases. Gene-nanoparticle complexes developed by scientists at the University of Buffalo, has proved to deliver therapeutic genes directly into the brains of living mice, the transfer rate is comparatively higher to transfer rates of viral vecto...Therapeutic Genes Transferred By Viral Vector Through T Cell Masking
Dr. Richard Vile, Mayo Clinic Molecular Immunologist and his team has found a new virus based gene therapy delivery system for the treatment of cancer, inflammation and autoimmune diseases. The new delivery system acts as a “T // cell Therapeutic hitchhiker”, by which the Therapeutic virus containing the required genes are transferred into the T cells in the immune system, as the T cells are the...EBV Antibody to Viral Capsid Antigen, IgA
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Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...EBV Antibody To Viral Capsid Antigen, IgG
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...HCSMC700 HME w/bacterial viral filter w/CO2
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NEW YORK--(BUSINESS WIRE)--May 15, 2007 - SIGA Technologies, Inc.(NASDAQ: SIGA) announced today the successful results of a proof ofconcept guinea pig trial of its lead Lassa fever virus drug,ST-193. This study was conducted under Biosafety Level 4 conditions atthe U.S. Army Medical Research Institute of Infectious Diseases(USAMRIID) by Dr. Kathleen Cashman under the supervision of Dr.Ma...