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Vesicular in Medical News

Virus evolution topic of Darwin talk at UH April 2

... pathogens evolve. Turner often performs basic research on non-dangerous viruses that serve as models for important pathogens. An example is the vesicular stomatitis virus that does not cause disease in humans but provides an excellent model for the sometimes deadly Dengue virus and other viruses transmi...

Neurocrine Biosciences Reports Fourth Quarter and Year-End 2008 Results

...n-GLP studies. The favorable results of these studies should allow urocortin 2 to be infused for periods up to two weeks in duration in humans. vesicular Monoamine Transporter 2 Inhibitor (VMAT2 ) VMAT2 is a protein concentrated in the human brain that is essential for the transmission of nerv...

Zebrafish Journal Publishes Skin Pigmentation Studies That Shed Light on the Evolution of Race

...its of the guppy, the link between pigment and fish behavior, and pigment dilution mutants in fish models connected to lysosome-related organelles and vesicular traffic genes. Zebrafish is an authoritative peer-reviewed journal published quarterly in print and online. This is the only peer-reviewed jo...

Tumor-killing virus selectively targets diseased brain cells

...e cells they target, conducted by senior author Anthony van den Pol, PhD, and his team at Yale University School of Medicine. They set out to test the vesicular stomatis virus, which was selected for its ability to attack brain tumors and leave healthy tissue largely uninfected. Tumor cells from brain cance...

Deafness and seizures result when mysterious protein deleted in mice

...ry perception, learning and memory. The missing protein is a particular vesicular neurotransmitter transporter, a machine within nerve cells that ferries che...aspects of behavior. Scientists have known for several years about two vesicular glutamate transporters, VGLUT1 and VGLUT2. As would be predicted, they are ...

Researchers train the immune system to deliver virus that destroys cancer in lab models

...cancer recurrence. The study appeared in the Dec. 9 online issue of Nature Medicine. The technology combines infection-fighting T-cells with the vesicular stomatitis virus that targets and destroys cancer cells while leaving normal cells unharmed. The study, which has not yet been replicated in humans, i...

Protein-dependent 'switch' regulates intracellular trafficking in epithelial cells

...g sickness not only of cells but of the organ of which those cells are a part," Dr. Kreitzer explains. Scientists have spent decades investigating vesicular trafficking. But the exact role for each of the 41 members of the kinesin family has remained unclear. In their study, Dr. Kreitzer's team focused ...

Study Revises Dynamin's Role in Nerve Cell Function

...icle recycling process,' Dr. Ryan explains. 'Essentially, the enzyme undergoes a chemical change whereby it physically squeezes off a piece of the old vesicular membrane creating a brand new vesicle poised to take on a new load of neurotransmitter.' Based on this work in fruit flies, neuroscientists h...

FMD tests at abattoir

...tted to the Institute for Animal Health.” Ms Reynolds said today: “Further negative laboratory test results for foot and mouth disease and swine vesicular disease mean that restrictions have been lifted on the slaughterhouse and the farm the pigs originated from.” YT ...

Hope for Marburg treatment: vaccine successful in primates

...that is said to be more effective as it is required in small doses and is easier to produce. The vaccine is med from the virus that causes the disease vesicular stomatitis in the farm animals. After genetically modifying the virus to make it harmless, inoculations of the live virus makes the human bodies to id...
Vesicular in Medical Technology

Epiphany Biosciences to Continue Phase 2 Shingles Study After Interim Analysis; Plans Follow-On Clinical Trial Studying Post-Herpetic Neuralgia (PHN)

...at sites throughout North America and uses an active comparator, valacyclovir. Outcomes assessed include various efficacy parameters including time to vesicular resolution and safety data collection. In addition to the Phase 2b zoster study, valomaciclovir will also be studied in a separate Phase 2 clinical ...

Avid Announces Results of AV-1 Molecular Imaging Agent for Alzheimer's Disease Presented at AD/PD Meeting

...id molecular imaging agents; two of which have now entered IND studies. Avid has also initiated an IND study of a new 18F-PET compound for imaging the vesicular monoamine transporter (VMAT-2) which is implicated in diseases involving dopaminergic degeneration such as Parkinson's disease (PD) and Dementia with ...
Vesicular in Medical Dictionary

Varicella

...ox or chicken pox is a highly contagious illness caused by primary infection with varicella zoster virus (VZV). It generally starts with a vesicular skin rash appearing in two or three waves, mainly on the body and... In the UK, varicella antibodies are measured as part of the routine o...

Stomatitis

...and ... Canker sores" - aphthous stomatitis or aphthous ulcers ... vesicular stomatitis is a sporadic, reemerging viral disease characterized by ... The incubation period for vesicular stomatitis ranges from 2 to 8 days. ... ... about the causes of stom...

Dyshidrotic eczema

...ecause of the risk of infection. ... Pompholyx ( dyshidrotic eczema , vesicular hand eczema ). Authoritative facts about the skin from the New Zealand... fluid filled ... Pompholyx, also known as dyshidrotic eczema , is a vesicular eczema of the palms and soles in which clear fluid filled, tense blisters...

Chickenpox

... or chicken pox is a highly contagious illness caused by primary infection with varicella zoster virus (VZV). It generally starts with a vesicular skin rash appearing in two or three waves, mainly on the body and... Although it's more common in kids under age 12, anyone can get chickenpo...

Chicken pox

... or chicken pox is a highly contagious illness caused by primary infection with varicella zoster virus (VZV). It generally begins with a vesicular skin rash appearing in two or three waves, mainly on the body and... Although it's more common in kids under age 12, anyone can get chickenpox...

Bacillus anthracis

...us anthracis is a large, rod shaped bacterium. ... Structure of a bacillus anthracis bacterium ... Bacillus anthracis . Marek's Disease. vesicular Stomatitis. Retraction. ADDL News. Printable ... Bacillus anthracis . Anthrax, caused by Bacillus anthracis , is ... Parent: Bacillus ant...
Vesicular in Biological News

Breakthrough technology observes synapse in real time, supporting theory of vesicular recycling

NEW YORK (Dec. 13, 2007) -- For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate. In doing so, they've also laid to rest a competing theory as to how key cellular processes ...

'Neurological work-arounds' offer hope to people with monoamine-related disorders

... To reach this conclusion, Krantz, Simon and colleagues bred fruit flies with what should have been a devastating, life-threatening mutation in the vesicular monoamine transporter gene. This mutation caused their brain cells to be unable to release monoamine neurotransmitters such as serotonin and dopamine....

Molecular Biology of the Cell celebrates 25 years of publication

...brane Transport of Small Molecules and the Electrical Properties of Membranes 12. Intracellular Compartments and Protein Sorting 13. Intracellular vesicular Traffic 14. Energy Conversion: Mitochondria and Chloroplasts 15. Mechanisms of Cell Communication 16. The Cytoskeleton 17. The Cell Cycle 18...

All eukaryotic kinases share 1 common set of substrates

...erally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death. Dysregulation of protein phosphorylation plays a major role in many diseases such as cancer and neurodegenerative...

Jefferson scientists find rabies-based vaccine could be effective against HIV

...ifferent immune system boosts, but didn’t see enhanced immune responses. They then developed a new vector, a viral surface protein from another virus, vesicular stomatitis virus (VSV). Two years after the initial immunization, they gave a booster vaccine with the rabies-VSV vector, and saw SIV/HIV-specific imm...

Ocean virus identified in human blood samples

...types of Vesiviruses ?named in part for the disease they can cause in hogs, vesicular exanthema of swine - are found in many other species. In a research arti...proven as a cause - with abortion, diarrhea, severe respiratory disease and vesicular disease. In another study to be published soon, a population of Thorough...

Researchers report breakthrough against world’s deadliest viruses

...we want it to go." The study describes how Canadian researchers developed the vaccines by replacing a surface protein in an animal pathogen, called vesicular stomatitis virus, with a surface protein from either the Ebola or Marburg viruses. Following extensive work, including trials with mice and guinea pig...

A puzzle piece found in unraveling the wiring of the brain

...the exocyst) which is known to be required for secretion (or exocytosis) of vesicular compartments in yeast. vesicular compartments are small organelles that transport proteins from one site to ...
Vesicular in Biological Technology

Neurocrine Biosciences Reports Second Quarter 2009 Results

...ion will be compared to standard-of-care treatment; enrollment of 50 subjects is planned. VMAT2 Update The highly selective blockade of the vesicular Monoamine Transporter 2 (VMAT2) with NBI-98854 should be of clinical benefit in patients with a variety of CNS diseases, especially those with involun...

Neurocrine Biosciences Reports First Quarter 2009 Results

... on the safety, tolerability and efficacy of UCN2 in this group. Initiation of this trial is expected in mid-2009 pending regulatory approval. vesicular Monoamine Transporter 2 Inhibitor (VMAT2 ) VMAT2 is a protein concentrated in the human brain that is essential for the transmission of nerv...

Mathematical models reveal how organisms transcend the sum of their genes

...ive rise to behavior?" He and Lim, now a postdoctoral fellow at the University of California-Berkeley, computationally modeled the lifecycle of the vesicular stomatitis virus (VSV), a well-studied virus with only five genes and years of background research on its growth and function. Virologists have pr...

New Mammalian Expression Vectors Employ Stable, High-Level Fluorescence Humanized Renilla GFP Reporter

... The pFB-hrGFP retroviral reporter vector is available as plasmid DNA and as a transduction-ready, replication-incompetent, vesicular stomatitis virus (VSV)-G pseudotyped high-titer retroviral supernatant. In plasmid form, the pFB-hrGFP retroviral vector must be...

Safe Production of High-Titer Retrovirus

...teins themselves (except for the VSV-G protein, which is derived from the vesicular stomatatitis virus). Host Range of Envelope Proteins (1,5) ...dered relatively safe compared with other viral systems. The vesicular stomatitis virus G protein (VSV-G) 5 is rapidly becoming the most popula...
Vesicular in Biological Products

Human Interferon Gamma Bioassay Services from PBL InterferonSource

Description:...of samples, although assay times may vary. The bioactivity of human interferon gamma is measured using human mesothelioma cells (H226) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 30-60 u/ml. Standard for Human IFN gamma (NIH reference: Gg23-901-530)....
Company:PBL InterferonSource

Pig Interferon Alpha Bioassay Services from PBL InterferonSource

Description:...eceipt of samples, although assay times may vary. The bioactivity of pig interferon alpha is measured using bovine kidney cells (MDBK) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 15-30 u/ml. Units are determined with respect to the Human IFN alpha 2a standard (NIH reference: Gxa01-90...
Company:PBL InterferonSource

Human Interferon Beta Bioassay Services from PBL InterferonSource

Description:...ceipt of samples, although assay times may vary. The bioactivity of human interferon beta is measured using monkey kidney cells (Vero) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 20-40 u/ml. Standard for Human IFN beta (NIH reference: Gxb02-901-535)....
Company:PBL InterferonSource

Human Interferon Omega Bioassay Services from PBL InterferonSource

Description:...eipt of samples, although assay times may vary. The bioactivity of human interferon omega is measured using bovine kidney cells (MDBK) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 15-30 u/ml. Standard for Human IFN omega (NIBSC Code: 94/754)....
Company:PBL InterferonSource

Human Interferon Alpha Bioassay Services from PBL InterferonSource

Description:...es may vary. The bioactivity of human interferon alpha is measured using bovine kidney cells (MDBK) or human mesothelioma cells (H226) challenged with vesicular stomatitis virus (VSV). Assay Sensitivity: 15-30 u/ml (MDBK), 5-10 u/ml (H226). Standard for Human IFN alpha 2a (NIH reference: Gxa01-901-535)....
Company:PBL InterferonSource
Vesicular in Biological Definition

Arbovirus

...es from different families and even orders can be arboviruses. List of arboviruses (not complete): Dengue fever Ross River virus vesicular stomatitis virus West Nile virus Yellow fever ...

Foot and mouth disease

... Symptoms of FMD in humans include malaise, fever, vomiting, red ulcerative lesions (surface-eroding damaged spots) of the oral tissues, and sometimes vesicular lesions (small blisters) of the skin. There is another viral disease with similar symptoms, commonly referred to as “hand, foot, and mouth dise...

Golgi apparatus

...by cisternae progression (the movement of the apparatus itself, building new cisternae at the cis face and destroying them at the trans face) or by vesicular transport (small vesicles transport the proteins from one cisterna to the next, while the cisternae remain unchanged). Lately, it is also proposed...

RNA virus

... Paramyxoviridae : Mumps Picornaviridae : Polio Reoviridae Retroviridae : Human Immunodeficiency Virus Rhabdoviridae : Rabies - vesicular stomatitis virus Togaviridae Filoviridae : Ebola See also DNA virus Virus classification ...

Vesicular stomatitis virus

... |- valign=top |Species:|| vesicular stomatitis Indiana virus |- valign=top |Species:|| vesicular stomatitis New Jersey virus vesicular stomatitis virus (VSV) is a virus in the famil...
Vesicular in Biological Dictionary

Sarcoplasmic reticulum

...lasmic reticulum was first obtained as paniculate material from ... Since the identification of the sarcoplasmic reticulum as the ATP-dependent vesicular ... But the primary function of the SARCOPLASMIC RETICULUM is to STORE CALCIUM IONS. Sarcoplasmic reticulum is very abundant in skeletal m...

Plasmalemma

...lemma is the sarcolemma. ... ... operating between the Golgi complex and the basolateral (sinusoidal) plasmalemma . ... plasmalemma by separate vesicular carriers as in glandular cells capable of ... They appear outside of plasmalemma in the separation cavity (Fig.15) ... Its membrane is in close...

Graafian follicle

...irected from Graafian follicle ) ... Mature vesicular follicles are sometimes called Graafian fol...he ovary containing a maturing ovum ... Mature vesicular follicles are sometimes called Graafian folli...medical term. What does ... graafian follicles vesicular ovarian f's; ... graafian follicle ... What...
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