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Protein discovery could unlock the secret to better TB treatment

UCL scientists have found a protein that could unlock the secret to quicker, more effective treatment of TB by waking TB bacteria in the body. Once the TB bacteria are active again, the disease becomes treatable using common drugs like antibiotics. Scientists believe that uncovering the molecular structure of this protein will lead the way to designing drugs which enable treatment of dormant and...

Timing is everything: First step in protein building revealed

Timing is everything, it seems, even inscience. A team led by Johns Hopkins scientists has unraveled the firststep in translating genetic information in order to build a protein,only to find that it's not one step but two.In a series of experiments, the scientists found that when yeast'sprotein-building machinery recognizes the starting line for a gene'sinstructions, it first alters its str...

Dinosaur DNA? New Patent Covers Degraded DNA recovery

The US Patent Office issued Patent # 6,872,552, "A Method of Reconstituting Nucleic Acid Molecules" today to Burt D. Ensley, Ph.D, Chairman of MatrixDesign, and CEO of DermaPlus, Inc. The patent covers methods for recovering and reconstituting genes from "degraded" DNA samples, and could allow scientists to reassemble everything from prehistoric, extinct animals to unsolved crime scenes. "...

Purdue proves concept of using nano-materials for drug discovery

Researchers at Purdue University have built and demonstrated a prototype for a new class of miniature devices to study synthetic cell membranes in an effort to speed the discovery of new drugs for a variety of diseases, including cancer. The researchers created a chip about one centimeter square that holds thousands of tiny vessels sitting on top of a material that contains numerous pores...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

Few things about growing older are asinevitable and obvious as “going gray,?yet scientists have been unableto explain the precise cause of this usually unwelcome transformation.In a report posted today on the Web site of the journal Science,researchers from Dana-Farber Cancer Institute and Children’s HospitalBoston say they have found the cellular cause of graying hair whileinvestigating th...

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Imaging Mass Spectrometry for Small Molecule Localization from Protein Discovery, Inc.

Description:ions and aligns them with histological images so you can localize drugs and metabolites prior to synthesizing radiolabeled c...
Company:Protein Discovery, Inc.

Small Non-coding RNA Discovery Microarray - Comprehensive Service from LC Sciences

Description:LC Sciences provides a comprehensive microarray service for systematic discovery of small regulatory/functional RNA embedded within non-coding RNAs (ncRNAs) using a novel Paraflo technology and proprietary probe design, which enables highly sensitive and specific direct detection of small RNAs (1). This comprehensive service includes custom probe design (according to submitted target RNA sequence...
Company:LC Sciences

BD Falcon Roller Bottle, smooth surface from BD Biosciences - Discovery Labware

Description:BD Falcon 850 cm Smooth-surface TufRol Roller Bottle, tissue-culture treated polystyrene, blow-molded one-piece design, with easy on/off non-vented cap, packed in double bag. (20/ca) Packaging: 20 / double pack, 20 / case...
Company:BD Biosciences - Discovery Labware

BD Falcon Roller Bottle, smooth surface from BD Biosciences - Discovery Labware

Description:BD Falcon 850 cm Smooth-surface TufRol Roller Bottle, tissue-culture treated polystyrene, blow-molded one-piece design, with easy on/off non-vented cap. (2/sp, 20/ca) Packaging: 2 / pack, 20 / case...
Company:BD Biosciences - Discovery Labware

BD Falcon 1536-well Black/Clear Microplates from BD Biosciences - Discovery Labware

Description:BD Falcon microtest assay plate. 1536 well 12l, black BD Optilux PS. Polystyrene, nonsterile, no lid (15/sp, 60/ca)...
Company:BD Biosciences - Discovery Labware

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pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins

Faster, easier screening for difficult transfections when using thecomplete control kit Stratagene We describe the vector pFB-ERV, an MMLV-based replication-defectiveretroviral vector for delivery of the ecdysone receptor proteins RXR and VgEcR.In stable cell lines infected with an estima...

High-Titer Retroviral Vectors for Gene Delivery

High-TiterRetroviral Vectors for Gene Delivery Stratagene The high-titer retroviral vectors pFB and pFB-Neo can be used with anyMoloney Murine L...

Recovery of DNA from LMP Agarose1

Resolve DNA fragments on a Low Melting Point (LMP) agarose gel in 1x Tris-Acetate-EDTA (TAE) buffer. Tris-Borate-EDTA (TBE) is not recommended as TBE gels are much more difficult to solubilize. Stain gel with Ethidium...

Efficient Recovery of Ultrapure Plasmid DNA

Nicole Passaretti, Vincent Prezioso, PhDBrinkmann Instruments, Inc., Westbury, NY Susanne WagnerEppendorfNethelerHinz GmbH, Hamburg, Germany Plasmids are naturally occurring, extrachromosomal DNA...

Effectene Transfection Reagent provides efficient gene delivery to primary neuronal cell cultures

Jochen Meier, Ivonne Strmel, Radu Iosub, Sonja Schmidt, and Rosemarie Grantyn Developmental Physiology, Johannes Mller Institute, Humboldt University Medical School (Charit), Berlin, Germany Efficient delivery of DNA to primary neuronal cell cultures is of critical importance...

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Oswald Avery

. He...

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Amphetamines Help Recovery of Stroke Patients

A new study from Doctors at UT Southwestern in Dallas soon report that amphetamines may speed up the recovery of speech in stroke patients who have lost the function. This study was done on patients who had suffered from ischemic stroke, or a stroke due to loss of blood and oxygen to the brain. Amphetamines were given to 30 stroke patients who lost their ability to spea...

Thyroid hormone treatment hastens recovery after cardiac surgery

Thyroid hormone treatment after surgery requiring heart bypass speeds recovery in children undergoing correction of congenital heart defects, according to a clinical trial published in The Lancet. The effects were greatest in the patients who underwent long and difficult surgeries. Following trauma or surgery or during a critical illness, thyroid hormone concentrations plummet. Ma...

Laboratory Testing Can Identify Risk of Pre-Term Labor and Delivery

A test for fetal fibronectin can predict whether a pregnant woman is at risk for early labor and delivery. Those at high risk for pre-term births are women with previous pre-term deliveries, those with multiple gestation pregnancy, and those who suffer from diabetes and/or hypertension. The current approach for finding whether a woman will go into premature labor is the use of a clinical...

Frozen Canadian baby stages miraculous recovery

When she was brought to the hospital, doctors declared her clinically dead, but lo and behold, she was awake and smiling on Monday in a miraculo...

Distraction therapy found very effective in postoperative patients

Controlling pain in patients following surgeries has been effectively taken care of by a new therapy called distraction therapy. Doctors at the Johns Hopkins Medical Institutions in the US have distracted patients with images and sounds from nature and have successfully controlled pain in patients following a painful procedure called bronchoscopy, which involves inserting the tube into t...

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Discovery Inline

Description:The Discovery Inline video magnifier is an easy to use, full color Auto-focus video magnifier that is designed so that the monitor (usually a television) sits on top of the video magnifier and is not built in. This allows for a change to a larger screen if desired in the future. Also available in black and white....
Company:Clarity

Discovery Inline Plus

Description:The Discovery Inline Plus is an easy to use, full color Autofocus video magnifier that is designed so that the monitor (either a computer or a television) sits on top of the video magnifier and is not built in. It has a built in SVGA adapter allowing it to be connected to a computer so that the magnified image from the video magnifier is displayed on the computer screen. It also has a feature cal...
Company:Clarity

Discovery M150 SE Microultracentrifuge

Description:Sorvall DiscoveryTMM150 SE Micro-ultra centrifuge continues to raise the standard for rapid, small volume sample processing, now with 1,048,000 x g performance and our new 4x5mL swinging bucket rotor. DiscoveryTMM150SE processes sample sizes from 0.2 ml to 8.3 ml, with a small floor footprint, brushless direct drive, very quiet operation, rotor imbalance detection, thermo-electric cooling, and a...
Company:ThermoFisher Scientific

Discovery M120 SE Microultracentrifuge

Description:The optimal combination of performance and rapid, small volume sample processing. New 4x5 mL swinging bucket rotor. DiscoveryTMM120 SE processes sample sizes from 0.2 ml to 8.3 ml, with a small floor footprint, brushless direct drive, very quiet operation, rotor imbalance detection, thermo-electric cooling, and automatic rotor locking....
Company:ThermoFisher Scientific

Discovery 100SE

Description:DiscoverySE Centrifuges. Workhorse. All in one. With speeds up to 100,000 rpm, the new Sorvall Discovery 100SE Ultracentrifuge offers unsurpassed performance. All the advanced features come with top-of-the-line performance, powerful functionality, and revolutionary ease of use, all built into the smallest, quietest, floor model ultra on the market....
Company:ThermoFisher Scientific

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New Quality Control Systems for Every Laboratory Application

Quality Control (QC) materials and procedures are key to meeting the needs of doctors and patients by verifying accuracy and precision of analytical methods. Vendors of these systems can be a valuable resource, designing customized QC materials and protocols to help lab managers ensure that analytical error st...

Urinalysis Analyzers: Large Capabilities in Every Size Device

Urine chemistry analysis, often conducted in a physicians office practice, can be instrumental in the detection of a wide array of ailments; UTIs, diabetes, several cancers, metabolic disorders, cardiovascular and kidney diseases. The estimated global market for urinalysis tests is well in excess of $600 million per year and is growing strongly. For such a fundamental, extensive and economic...

Pieris Progresses Proprietary Asthma Program: Validation of Pulmonary Delivery of Anticalin-Based Protein Product Candidate

FREISING-WEIHENSTEPHAN, Germany, July 10, 2007 /PRNewswire/ --Pieris AG, a bio-pharmaceutical company developing Anticalins(R), anovel class of targeted human protein therapeutics, today announcedsignificant progress in validating novel, effective products forthe potential treatment of asthma. In studies of its proprietaryPRS-060 Anticalin(R) candidate, the Company reports that theprotei...

TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment

LOD, Israel--(BUSINESS WIRE)--Jul 9, 2007 - TransPharma MedicalLtd., a specialty pharmaceutical company focused on the developmentand commercialization of drug products utilizing a proprietaryactive transdermal drug delivery technology, announced todaypromising results of its phase I clinical trials demonstrating thesafety and pharmacokinetic profile of its ViaDerm-hPTH (1-34)product for th...

Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme

CAMBRIDGE, U.K. 2nd July 2007 - CeNeS Pharmaceuticals (AIM:CEN)("CeNeS" or "the Company") the Cambridge-based biopharmaceuticalcompany today announced that a paper published this week in CNSDrugs(1) further supports the hypothesis that acatechol-O-methyltransferase (COMT) inhibitor that acts in thebrain would be a useful agent to address profound cognitivedeficits in schizophrenia and bi...

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Recovery

This is a time of <b...