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Vasomotor in Medical News

More Clinical Data Required to Support European Approval of Desvenlafaxine as a Potential Treatment for Vasomotor Symptoms

MADISON, N.J., March 12 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), announced today that it would need to conduct additional clinical studies to address questions from the Committee for Medicinal Products for Human Use (CHMP) regarding the risk-benefit p...

Menopause Is More Than A Hot Flash

...s been without her period for a full year. While some women experience no menopausal symptoms, others suffer severe symptoms that require treatment. vasomotor symptoms (hot flashes and night sweats) and vaginal atrophy are the most common menopausal symptoms. Although the majority of women experience "natur...

New Data: Efficacy and Responder Analyses of Divigel(R) (estradiol gel) 0.1 percent for the Treatment of Menopause

...cy trial were to determine the percent of postmenopausal women who achieved a greater than 50 percent reduction in the frequency of moderate to severe vasomotor symptoms (MSVMS), or hot flashes, and to assess the change from baseline in a quality of life (Kupperman) index score that evaluated various menopausa...

Quality of life may impact coping strategies of young women with breast cancer

... From a developmental perspective, younger women face unique issues such as premature onset of menopause that may lead to infertility, sudden onset of vasomotor symptoms (hot flashes and/or night sweats) and long-term consequences of ovarian decline; changes in relationships with one's partner and/or children;...

Newly Published Menopause Study: 'Bioidentical' and FDA-Approved Divigel(R) (estradiol gel) 0.1 Percent Safe and Effective Treatment for Moderate to Severe Hot Flashes Associated With Menopause

...adiol gel or lotion available for the treatment of vasomotor symptoms (1-4). Data showed a statistically signi...daily frequency and severity of moderate to severe vasomotor symptoms. Change from baseline in the signs of vul...ignificant reductions in frequency and severity of vasomotor symptoms from baseline compared with placebo, as e...

FDA Approves Duramed's Synthetic Conjugated Estrogens-A Vaginal Cream

...has been without her period for a full year. While some women experience no menopausal symptoms, others suffer severe symptoms that require treatment. vasomotor symptoms (night sweats, hot flashes) and vaginal symptoms (such as vaginal dryness and pain with intercourse) are common menopausal symptoms. Although...

Hot Flashes, Night Sweats a Good Sign for Breast Cancer Patients

...urrence rate after nine years (18 percent) than women who didn't report new vasomotor symptoms (23 percent). The 31.4 percent of women who reported new joint sym...e December print issue of The Lancet Oncology . "The appearance of new vasomotor symptoms or joint symptoms within the first three months is a useful biomar...

KV Pharmaceutical Company Reports Fiscal 2009 First Quarter Results

...g option for women experiencing moderate-to-severe vasomotor symptoms associated with menopause, particularly w...d provides convenient relief of moderate-to-severe vasomotor symptoms. Evamist(TM) targets an annual $1.3 bil... unprecedented number of women may be experiencing vasomotor symptoms related to menopause: the Centers for Dis...

Sleep problems associated with menopause vary among ethnic groups

...again. They were also asked about the frequency of vasomotor systems such as hot flashes, cold sweats, and nigh...were hormone users did not influence the effect of vasomotor systems or changing hormone levels on sleep sympto...sleep and waking several times. Women who reported vasomotor symptoms on more days in the preceding two weeks a...

Hot flashes underreported and linked to forgetfulness

... memory dysfunction," Maki said. "So, the two together worsen memory in women the next day." The study suggests that if women are treated for their vasomotor symptoms it may improve memory function in women with hot flashes, said Maki. ...
Vasomotor in Medical Technology

Wyeth Reports Publication of Phase 3 Data for Bazedoxifene/Conjugated Estrogens, an Investigational Compound Being Studied for the Treatment of Menopausal Symptoms

...for the treatment of moderate-to-severe menopausal vasomotor symptoms such as hot flushes, night sweats and vul...one mineral density (BMD) at two years, menopausal vasomotor symptoms at four and 12 weeks, vaginal maturation ...o 64 years). Of these women, 17 million experience vasomotor symptoms; 9 million experience moderate to severe ...

Radius Initiates Phase 2a Clinical Trial of RAD1901 in Menopausal Hot Flashes

... company's first-in-class SERM designed to relieve vasomotor symptoms without side effects associated with horm...M) undergoing clinical evaluation for treatment of vasomotor symptoms (menopausal hot flashes). The clinical tr...nstrated positive effects in preclinical models of vasomotor symptoms and a favorable safety profile in Phase I...

Independent Physician Surveys Show if Approved, MF101 Could Become First-Line Treatment for Menopause Symptoms

... list of treatment options for menopausal symptoms, physicians also reported the following: -- The accepted threshold for efficacy of a drug for vasomotor symptoms is a 58% reduction in moderate to severe hot flashes, and, -- The number one concern for women when considering treatment options for ...

Wyeth Presents New Phase 3 Data and Updates Regulatory Timing for NDA Filing of Bazedoxifene/Conjugated Estrogens

...20 million women of menopausal age (45-54 years) in the United States. As many as 50 percent to 90 percent of women going through menopause experience vasomotor symptoms, such as hot flashes, which can greatly impact a woman's life. Furthermore, between 10 percent and 40 percent of postmenopausal women experie...

New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes

...enopausal women presenting with moderate to severe vasomotor symptoms. The study compared placebo to Divigel(R)...ificant reduction in the frequency and severity of vasomotor symptoms by week four. The Divigel(R) 0.25 g group...ificant reduction in the frequency and severity of vasomotor symptoms by week seven. Statistically significant ...

Wyeth Presents Phase 3 Data for Pristiq, an Investigational Non-Hormonal Therapy for Menopausal Hot Flashes and Night Sweats

...nlafaxine) for the treatment of moderate-to-severe vasomotor symptoms (hot flashes and night sweats) associated...svenlafaxine Succinate for Treatment of Menopausal vasomotor Symptoms This one-year, multicenter, randomized,...nlafaxine Succinate in the Treatment of Menopausal vasomotor Symptoms This six month multicenter, randomized,...

Bionovo's MF101 Shows Positive Safety, Tolerability and Efficacy in Phase 2 Trial

...ptoms. The favorable dose response trend signals that MF101 may become a clear alternative to traditional postmenopausal hormone therapy for relief of vasomotor symptoms. We are excited by the prospect of moving forward with the development of a product that could potentially have such broad reach and positive...

New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy

...transdermal estrogen therapy that was approved by the U.S. Food and Drug Administration (FDA) in December 2006 for the treatment of moderate-to-severe vasomotor symptoms (hot flashes) associated with menopause. About Estrogens Estrogen products today are approved for the treatment of menopausal symptoms, i...

New Proof of Genistein's Efficacy and Safety for Osteopenia and Osteoporosis Published in Annals of Internal Medicine

... baseline and 6 percent per year over those taking the placebo. -- No adverse events were reported in the study. All participants were monitored for vasomotor symptoms, vaginal bleeding, breast tenderness, endometrial thickness, depression, irritability, insomnia, and gastrointestinal (GI) symptoms, as well ...
Vasomotor in Medical Definition

Pathology

...ronchopneumonia ) Other acute lower respiratory infections Bronchitis - Bronchiolitis Other diseases of upper respiratory tract vasomotor rhinitis - Hay fever - Atrophic rhinitis - Nasal polyp - Adenoid hypertrophy - Peritonsillar abscess - Vocal fold nodule - Laryngospasm ...
Vasomotor in Medical Dictionary

Vasomotor rhinitis

...ipping. It is caused by chronic or acute... vasomotor rhinitis affects millions of Americans and resu.... ... No specific test is available to diagnose vasomotor rhinitis . ... vasomotor rhinitis . Postural reflexes. Primary ciliary dy...

Vasoconstriction

...iated with renal vasoconstriction favour the vasodilatory response ... Vasoconstriction , narrowing of blood vessels. It is mediated by the vasomotor center in the brain stem, causing reflex changes in the heart rate with. Wolff suggested that the vasoconstriction occurring during the aura ...
Vasomotor in Biological News

Heart protein regulates blood vessel maintenance

...of the BMPs. "We also found that FHL2 is important in the regulation of vasomotor tone, or the contraction and relaxation of muscles in the blood vessel. This is important because dysfunction in vasomotor tone is thought to cause high blood pressure. Our study demonstrates that F...

Study finds link between hot flashes and lower bone density in women

... between the ages of 42 and 52 who participated in the bone sub-study of the Study of Women's Health Across the Nation to determine whether women with vasomotor symptoms (VMS) which include hot flashes and night sweats had lower bone mineral density. The researchers found that postmenopausal women wit...

PET imaging shows young smokers quick benefit of quitting

...e to cold stimulation (also called 15O-water PET) in healthy young smokers," noted the co-author of "Smoking Cessation Normalizes Coronary Endothelial vasomotor Response Assessed With 15O-Water and PET in Healthy Young Smokers." Researchers from the Japanese university also noted that improvement was "preserve...
Vasomotor in Biological Technology

Hot Information for Physicians Treating Vasomotor Symptoms During the Menopausal Transition

MONTVALE, N.J., March 25 /PRNewswire/ -- How long is the menopausal transition? New data suggest that it's longer than most women -- and their health care providers -- think. Clinicians often face challenges determining if women will experience menopausal symptoms and when and how long these s...

Study Data Results Showed Desvenlafaxine Significantly Reduced Moderate to Severe Vasomotor Symptoms in Menopausal Women Versus Placebo

COLLEGEVILLE, Pa., Oct. 15 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), reported that new study data presented today at the 63rd Annual Meeting of the American Society for Reproductive Medicine (ASRM) showed that women who received 100 mg/day or 150 mg/da...

Bionovo Announces Publication of Positive Phase 2 Trial Results for Menerba(TM)

...f a peer-reviewed article in the journal, Menopause, reporting Menerba(TM) (formerly MF101) is well tolerated, safe and effective for the treatment of vasomotor symptoms (hot flashes and night sweats) associated with menopause. The Phase 2 clinical trial was designed to evaluate the safety and efficacy ...

Azur Pharma Ltd. Enters Into Definitive Agreement With BioSante Pharmaceuticals Inc [nasdaq: BPAX], to Acquire U.S. Rights to Elestrin (TM)

...ion of estradiol which is indicated for the treatment of moderate to severe vasomotor symptoms associated with menopause. Elestrin was approved by the U.S. Food ...FDA approval by BioSante, indicated for the treatment of moderate-to-severe vasomotor symptoms associated with menopause, currently marketed in the U.S. ...

Vasomotor Symptoms? Create an Individual Treatment Plan for Your Patient

...wire/ -- The increasing frequency and intensity of vasomotor symptoms is a challenge for women experiencing men...tice have recently published a supplement titled vasomotor symptoms: Managing the transition from perimenopau...cotherapies, and alternative medicines in treating vasomotor symptoms. OBG Management - - The number ...

Retrospective Analysis of Phase 3 Data Suggest Wyeth's Investigational Compound Bazedoxifene/Conjugated Estrogens Comparable to Placebo on Incidence of Abnormal Mammograms

... of Wyeth (NYSE: WYE ), for the treatment of moderate-to-severe menopausal vasomotor symptoms such as hot flashes and night sweats, and for the prevention of po...any as 50 percent to 90 percent of women going through menopause experience vasomotor symptoms, such as hot flashes, which can greatly impact a woman's life. Fur...

Bionovo Reports First Quarter 2008 Financial Results

...ults from two independent physician surveys which showed the Company's drug candidate MF101 could become first-line treatment for menopausal vasomotor symptoms (hot flashes). In both qualitative and quantitative studies, 124 board certified physicians in internal medicine or obstetrics and ...

FDA Approves PRISTIQ(TM) for the Treatment of Adult Patients with Major Depressive Disorder

...ill be approved in the future for other indications (including treatment of vasomotor symptoms associated with menopause) and/or in other countries. Other risks ...afaxine for the treatment of major depressive disorder and the treatment of vasomotor symptoms, as to which no assurance can be given); government cost-containme...

Novavax Enters Into Estrasorb(R) Asset Sale and Supply Agreements with Graceway Pharmaceuticals, LLC

...a supply agreement for the product with Graceway Pharmaceuticals, LLC(TM) ("Graceway"). Estrasorb is indicated for the treatment of moderate to severe vasomotor symptoms associated with menopause. Novavax will retain the rights to commercialize Estrasorb in other parts of the world. In a separate but related...

KV Pharmaceutical Company Reports Record Revenues for Fiscal 2008 Second Quarter and Six Months on a Preliminary Basis

...uisition of Evamist(TM), a transdermal estradiol spray for the treatment of vasomotor symptoms associated with menopause. Excluding this write-off, earnings (non...ed dose transdermal estradiol spray for the treatment of moderate to severe vasomotor symptoms due to menopause. The Company expects to launch the product after ...
Vasomotor in Biological Definition

Thermoregulation

... by the skin, respiration becomes far more important. But for man the great heat regulator is undoubtedly the skin, which regulates heat loss by its vasomotor mechanism, and also by the nervous mechanism of perspiration. Dilatation of the cutaneous vascular areas leads to a larger flow of blood through the s...
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