variants

UCSD researchers discover variants of natural tumor suppressor

Building on their 2005 discovery of an enzyme that is a natural tumor suppressor, researchers at the University of California, San Diego (UCSD) School of Medicine have now identified two variants of that enzyme which could provide new targets for therapies to treat diabetes, heart and neurological disease. The findings, by Alexandra C. Newton, Ph.D., UCSD professor of pharmacology, and colleague...

Identified main genetic variants involved in response to HIV

This international collaboration has been the largest ever to have taken place in a large scale study on genetic differences between patients infected by HIV, and is the first study of this kind in the field of infectious disease. Catalan participants have been coordinated by Javier Martínez-Picado, ICREA research professor in the Foundation irsiCaixa of Hospital Germans Trias i Pujol, and Jos...

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Using XL1-Red Mutator Strain to Generate Esterase Variants

XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...

Purification and Characterization of beta-Lactoglobulin Genetic Variants A and B Using Preparative Electrophoresis and Isoelectric Focusing

K. H. Valkonen*, N. Marttinen*, H.-L. Malinen*, V.-P. Jaakola** and T. Alatossava* * Biotechnology Laboratory, REDEC of Kajaani, University of Oulu, FIN-88600 Sotkamo, Finland ** Department of Biological and Environmental Science, University of Jyvskyl, PL 35, FIN-40351 Jyvskyl, Finland...

Detection of Apolipoprotein Gene Variants by DGGE Using the DCode System

Clive R. Pullinger, Arghavan K. Shahidi, Andrea L. Verhagen and John P. Kane Department of Biochemistry and Biophysics, University of California, San Francisco, California In a numb...

variants at Medicine News

Gene Variants Linked to Early Heart Attack Discovered

Two gene variations have been discovered by scientists at UCSF, Celera Genomics and The Cleveland Clinic which have been linked to an increased risk// for early heart attack, or myocardial infarction (MI). One of the genes, known as VAMP8, normally expresses a protein essential for early stages of clotting. When clotting occurs in a coronary blood vessel, it can lead to heart attack. Kn...

Striking a Gold Mine: H5N1 Vaccine may Serve as an Antidote for Mutants and Variants

As a breather and news that spells heaven for millions of avian influenza patients there is a research by scientists at St. Jude Children’s Research Hospital //. According to them they have developed in the lab a vaccine that is potent against one antigenic variant of the avian influenza virus H5N1. The scientific discovery is that this vaccine also has the ability to protect humans again...

Susceptibility Of TB In Humans Might Be Due To Three Human Gene Variants

A new study has reported that there appears to be three variations of a human gene that seem to cause an impact on humans upon their susceptibility towards tuberculosis// . Researchers hope that these findings would provide sufficient knowledge as to why some patients infected with the Mycobacterium tuberculosis pathogen develop the full-blown disease while others are seemingly not affect...

Gene variants hold clues about vulnerability to cardiovascular disease

Researchers led by Duke University Medical Center scientists have discovered that alterations in a gene that triggers other genes may hold clues to the reasons why// certain people are vulnerable to heart disease. This gene termed, as GATA2 and the army of genes it manipulates may actually show an individual’s propensity to coronary artery disease. This finding may also show the way for t...

Gene Variants Linked to Preterm Birth in Hispanic Women

Four gene variants in Hispanic women are linked to spontaneous preterm birth, according to researchers at Yale School of Medicine and Washington University.// The research was presented at the Society for Gynecologic Investigation Conference in Reno, Nevada on March 16. Preterm birth is a major cause of illness and death in newborns. A genetic cause of preterm birth was su...

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ultra2 A1c and Hemoglobin Variants Analyzer

Description:The ultra2 is an HPLC system designed to provide fast and accurate measurements of patient hemoglobin levels and aid in the comprehensive identification and quantitation of hemoglobin variants delivering unparalleled results for glycemic control. The A1c assay combines the speed and precision of HPLC with the accuracy of boronate affinity columns. The result is a precise assessment of tru...
Company:Primus Corporation

variants at Medicine Technology

ACC Presentation Indicates Interleukin-1 Gene Variants Determine Increased Risk for Coronary Artery Disease from Oxidized Phospholipids

WALTHAM, Mass.--(BUSINESS WIRE)--Mar 27, 2007 - InterleukinGenetics, Inc. (AMEX:ILI) and collaborators at the University ofCalifornia San Diego today reported at the American College ofCardiology annual meeting that associations between coronary arterydisease (CAD) and both oxidized phospholipids (OxPL) and Lp(a)levels appear to be dependent on pro-inflammatory variants of theinterleukin-1...